BacMap

Definition	Nostoc sp. PCC 7120, complete genome.
Accession	NC_003272
Length	6,413,771

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The map label for this gene is hetN [H]

Identifier: 17231245

GI number: 17231245

Start: 4530462

End: 4531253

Strand: Reverse

Name: hetN [H]

Synonym: all3753

Alternate gene names: 17231245

Gene position: 4531253-4530462 (Counterclockwise)

Preceding gene: 17231251

Following gene: 17231242

Centisome position: 70.65

GC content: 36.99

Gene sequence:

>792_bases
ATGAACACAACACATAAGCAGACTGCTCTAATTACTGGTGCAGCTAGTGGTATTGGTTATGAATTAGTGTGTATTTTCGC
TGAAAATGATTACAATCTCGTATTAGTAGATCGGGCAAAGGAAAAACTAGAAGAAATAGCGATTGAGTTTCAAGATAAAT
TCGGAATTTCTGTTAAGCCTATTGTCCGAGATTTATCTAAAACAACATCTCCTGAAGAAATTTTTCAAGAGGTAGAACAG
GCAAATATTAAAGTTGATGTGCTAGTCAATAATGCTGGGTTTGGTACTTATGGATTATTTAATGACACTAACCTTACTGA
TGAACTAGAAATGCTACAGGTAAATGTGGTATGTACTACCCATTTAACTAAGTTATTTCTCAAAAATATGGTTCAGCAAG
GTGAGGGAAAAATATTAAATGTCTCTTCTGCTGCGGCTTTTCAACCAGGGCCTTTGATGGCCGTTTATTTTGCGACTAAA
GCCTACGTATTATCTTTTTCTGAAGCACTCGCCAATGAATTAGACGGTACAGGTGTCACTGTGACGGTTCTTTGCCCAGG
AACAACACAGTCTGCTTTCCATCAAAGAACGGGGATGGCAGATTCTAAACTAGTCAAAGGTAAAAGGATGATGGATGCGT
CAACAGTAGCCGATATTGGTTATCGTGGTTTAATGCAGGGTAAAACAATTGTTATTCCTGGTTTGATCAATAAAATCATG
GCGAAAAGTATCAGATTTATCCCCAGGAAACTAGTAACTAAAATTGTCAGGAATATGCAGGAAAATAAATAA

Upstream 100 bases:

>100_bases
TTATCATTTTGGTTTTTAAAATAGGTCAATTCCTTAATTATCAAGTCTCTTTTGATAAATACAGACCTAGTTAATCTATT
GAAATCACCCAACATCAAAC

Downstream 100 bases:

>100_bases
TGATCTATTTGGTCGATAGTTATTAATAATTAAGTGTTGAGTTGAAAATTAAGACTTCCAACCCAACACTTCCTAATTTT
CTTGAGACATTGAATTAACA

Product: hypothetical protein

Products: 3-oxoacyl-[acyl-carrier protein]; NADPH; H+

Alternate protein names: NA

Number of amino acids: Translated: 263; Mature: 263

Protein sequence:

>263_residues
MNTTHKQTALITGAASGIGYELVCIFAENDYNLVLVDRAKEKLEEIAIEFQDKFGISVKPIVRDLSKTTSPEEIFQEVEQ
ANIKVDVLVNNAGFGTYGLFNDTNLTDELEMLQVNVVCTTHLTKLFLKNMVQQGEGKILNVSSAAAFQPGPLMAVYFATK
AYVLSFSEALANELDGTGVTVTVLCPGTTQSAFHQRTGMADSKLVKGKRMMDASTVADIGYRGLMQGKTIVIPGLINKIM
AKSIRFIPRKLVTKIVRNMQENK

Sequences:

>Translated_263_residues
MNTTHKQTALITGAASGIGYELVCIFAENDYNLVLVDRAKEKLEEIAIEFQDKFGISVKPIVRDLSKTTSPEEIFQEVEQ
ANIKVDVLVNNAGFGTYGLFNDTNLTDELEMLQVNVVCTTHLTKLFLKNMVQQGEGKILNVSSAAAFQPGPLMAVYFATK
AYVLSFSEALANELDGTGVTVTVLCPGTTQSAFHQRTGMADSKLVKGKRMMDASTVADIGYRGLMQGKTIVIPGLINKIM
AKSIRFIPRKLVTKIVRNMQENK
>Mature_263_residues
MNTTHKQTALITGAASGIGYELVCIFAENDYNLVLVDRAKEKLEEIAIEFQDKFGISVKPIVRDLSKTTSPEEIFQEVEQ
ANIKVDVLVNNAGFGTYGLFNDTNLTDELEMLQVNVVCTTHLTKLFLKNMVQQGEGKILNVSSAAAFQPGPLMAVYFATK
AYVLSFSEALANELDGTGVTVTVLCPGTTQSAFHQRTGMADSKLVKGKRMMDASTVADIGYRGLMQGKTIVIPGLINKIM
AKSIRFIPRKLVTKIVRNMQENK

Specific function: May be involved in repressing heterocyst differentiation and may be essential for preventing all vegetative cells from differentiating [H]

COG id: COG0300

COG function: function code R; Short-chain dehydrogenases of various substrate specificities

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI4557649, Length=190, Percent_Identity=36.8421052631579, Blast_Score=108, Evalue=7e-24,
Organism=Homo sapiens, GI7705855, Length=265, Percent_Identity=27.9245283018868, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI226371731, Length=226, Percent_Identity=29.646017699115, Blast_Score=89, Evalue=3e-18,
Organism=Homo sapiens, GI7706318, Length=186, Percent_Identity=33.3333333333333, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI210032110, Length=265, Percent_Identity=28.3018867924528, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI20149619, Length=212, Percent_Identity=29.2452830188679, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI32483357, Length=199, Percent_Identity=26.6331658291457, Blast_Score=78, Evalue=6e-15,
Organism=Homo sapiens, GI142976729, Length=194, Percent_Identity=34.020618556701, Blast_Score=78, Evalue=8e-15,
Organism=Homo sapiens, GI40254992, Length=178, Percent_Identity=29.2134831460674, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI126723191, Length=181, Percent_Identity=27.6243093922652, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI109715829, Length=200, Percent_Identity=26, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI31542939, Length=192, Percent_Identity=31.25, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI66933014, Length=168, Percent_Identity=30.3571428571429, Blast_Score=65, Evalue=5e-11,
Organism=Homo sapiens, GI33667109, Length=192, Percent_Identity=28.125, Blast_Score=65, Evalue=8e-11,
Organism=Escherichia coli, GI87082100, Length=197, Percent_Identity=31.4720812182741, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1787820, Length=180, Percent_Identity=31.1111111111111, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1787335, Length=181, Percent_Identity=25.9668508287293, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1786701, Length=192, Percent_Identity=26.5625, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI87082160, Length=181, Percent_Identity=28.1767955801105, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1788459, Length=199, Percent_Identity=26.1306532663317, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI1786812, Length=188, Percent_Identity=28.1914893617021, Blast_Score=64, Evalue=7e-12,
Organism=Escherichia coli, GI1787526, Length=188, Percent_Identity=26.5957446808511, Blast_Score=61, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI71994604, Length=194, Percent_Identity=31.4432989690722, Blast_Score=90, Evalue=9e-19,
Organism=Caenorhabditis elegans, GI71994600, Length=193, Percent_Identity=31.6062176165803, Blast_Score=87, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI17562904, Length=205, Percent_Identity=30.7317073170732, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17562908, Length=205, Percent_Identity=29.7560975609756, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI72000259, Length=210, Percent_Identity=31.4285714285714, Blast_Score=74, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17562906, Length=203, Percent_Identity=28.5714285714286, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17508895, Length=199, Percent_Identity=28.1407035175879, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17551412, Length=197, Percent_Identity=27.4111675126904, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17562910, Length=216, Percent_Identity=27.3148148148148, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI25152911, Length=186, Percent_Identity=29.5698924731183, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17560220, Length=202, Percent_Identity=28.7128712871287, Blast_Score=70, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17563726, Length=200, Percent_Identity=28, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17562990, Length=209, Percent_Identity=29.1866028708134, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI115534694, Length=204, Percent_Identity=28.921568627451, Blast_Score=65, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17559104, Length=204, Percent_Identity=26.9607843137255, Blast_Score=64, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI193203115, Length=209, Percent_Identity=30.622009569378, Blast_Score=64, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI193203117, Length=209, Percent_Identity=30.622009569378, Blast_Score=64, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI193204405, Length=209, Percent_Identity=27.7511961722488, Blast_Score=64, Evalue=9e-11,
Organism=Saccharomyces cerevisiae, GI6319635, Length=226, Percent_Identity=25.6637168141593, Blast_Score=73, Evalue=5e-14,
Organism=Saccharomyces cerevisiae, GI6323882, Length=196, Percent_Identity=29.0816326530612, Blast_Score=71, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6322067, Length=187, Percent_Identity=31.0160427807487, Blast_Score=69, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24640442, Length=188, Percent_Identity=36.1702127659575, Blast_Score=107, Evalue=9e-24,
Organism=Drosophila melanogaster, GI24584752, Length=182, Percent_Identity=34.0659340659341, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24584744, Length=198, Percent_Identity=34.3434343434343, Blast_Score=99, Evalue=4e-21,
Organism=Drosophila melanogaster, GI28574402, Length=198, Percent_Identity=34.3434343434343, Blast_Score=99, Evalue=4e-21,
Organism=Drosophila melanogaster, GI24584748, Length=187, Percent_Identity=32.620320855615, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI161076933, Length=187, Percent_Identity=32.620320855615, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24644339, Length=190, Percent_Identity=34.7368421052632, Blast_Score=91, Evalue=6e-19,
Organism=Drosophila melanogaster, GI28571526, Length=206, Percent_Identity=31.0679611650485, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI21358495, Length=208, Percent_Identity=28.8461538461538, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI21357041, Length=206, Percent_Identity=28.6407766990291, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24580925, Length=211, Percent_Identity=29.8578199052133, Blast_Score=74, Evalue=8e-14,
Organism=Drosophila melanogaster, GI23397609, Length=197, Percent_Identity=28.9340101522843, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI116007236, Length=232, Percent_Identity=27.1551724137931, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI21355631, Length=258, Percent_Identity=28.2945736434109, Blast_Score=65, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.1.1.100

Molecular weight: Translated: 28848; Mature: 28848

Theoretical pI: Translated: 8.05; Mature: 8.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTTHKQTALITGAASGIGYELVCIFAENDYNLVLVDRAKEKLEEIAIEFQDKFGISVKP
CCCCCCCEEEEEECCCCCCEEEEEEEECCCCEEEEEHHHHHHHHHHHHHHHHHCCCCHHH
IVRDLSKTTSPEEIFQEVEQANIKVDVLVNNAGFGTYGLFNDTNLTDELEMLQVNVVCTT
HHHHHHCCCCHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCCCCEEEEEEEEHHHH
HLTKLFLKNMVQQGEGKILNVSSAAAFQPGPLMAVYFATKAYVLSFSEALANELDGTGVT
HHHHHHHHHHHHCCCCCEEEECCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHCCCCCEE
VTVLCPGTTQSAFHQRTGMADSKLVKGKRMMDASTVADIGYRGLMQGKTIVIPGLINKIM
EEEEECCCCHHHHHHHCCCCHHHHHCCHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHH
AKSIRFIPRKLVTKIVRNMQENK
HHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNTTHKQTALITGAASGIGYELVCIFAENDYNLVLVDRAKEKLEEIAIEFQDKFGISVKP
CCCCCCCEEEEEECCCCCCEEEEEEEECCCCEEEEEHHHHHHHHHHHHHHHHHCCCCHHH
IVRDLSKTTSPEEIFQEVEQANIKVDVLVNNAGFGTYGLFNDTNLTDELEMLQVNVVCTT
HHHHHHCCCCHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCCCCEEEEEEEEHHHH
HLTKLFLKNMVQQGEGKILNVSSAAAFQPGPLMAVYFATKAYVLSFSEALANELDGTGVT
HHHHHHHHHHHHCCCCCEEEECCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHCCCCCEE
VTVLCPGTTQSAFHQRTGMADSKLVKGKRMMDASTVADIGYRGLMQGKTIVIPGLINKIM
EEEEECCCCHHHHHHHCCCCHHHHHCCHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHH
AKSIRFIPRKLVTKIVRNMQENK
HHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: (3R)-3-hydroxyacyl-[acyl-carrier protein]; NADP+

Specific reaction: (3R)-3-hydroxyacyl-[acyl-carrier protein] + NADP+ = 3-oxoacyl-[acyl-carrier protein] + NADPH + H+

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8157596; 11759840 [H]