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The map label for this gene is yicJ [C]

Identifier: 17231197

GI number: 17231197

Start: 4473345

End: 4474808

Strand: Direct

Name: yicJ [C]

Synonym: alr3705

Alternate gene names: 17231197

Gene position: 4473345-4474808 (Clockwise)

Preceding gene: 17231195

Following gene: 17231198

Centisome position: 69.75

GC content: 41.19

Gene sequence:

>1464_bases
ATGAACGACTCTGCTGCTGATGGTTATGCCCAAAAGCCTAAGAATAGTCAAAAATTAGATTTGAAAACCAAGCTGGCTTA
CGGTGCTGGTGATTTAGGCCCAGCAATTACCGCCAATATTTCTATATTCTTTCTATTAATTTTCTTTACCAACGTTGCTG
GTATTCCGGCTGGTTTGGCGGGTAGTGTTTTAATGATTGGGAAAATCTGGGACGCTGTTAACGATCCTTTCGTGGGGGTA
TTGACGGATAAAACAAAGTCTCGGCGGTGGGGTCGTCGTTTGCCTTGGATGCTTTATGGGGCAATTCCTTTTGGAATTTT
CTTTTTCTTACAGTGGATTGTACCGCGATTTAGTAGCGACCAGGGTAGTAATGTTTGGGCTTTGTTTTGGTATTACGTAG
TGATTGGGTTGATTTCCCAGGTGTTTTATACAGTTGTAAACCTGCCTTATACAGCCCTGACTCCAGAACTTACCCAAGAT
TATGACGAACGCACTAGCCTGAATAGTTTTCGCTTTGCCTTTTCTATTGGTGGCAGCATTTTATCTTTAATTTTATCTAA
AGTTGTTTTGTCGTTGATTAGCGATCGCCAGCAACAGTATATAGTTTTAGCAGCAATTTGCACCGTCATCTCGGTTATAT
CATTATATTGGTGCGTCTTTGGCGTGCGCGAGCGGGTATTGGCATTTGAAGCAAAACGTATTCAAGTTGAGGAATCTGAC
TCTATCCCTTTCTTTGAACAATTAAAAATTGTTTTCAGCAATCGCCCCTTTCTATTTGTAATTGGCATATATTTGTTTTC
TTGGTTAGGAGTACAAATAACAGCCAGCATTATTCCCTACTTTGTCATCAATTGTATGTCTCTGCCTGAATCAGATGTAC
CCACAACGATGATTGCAGTACAAGGGACTGCTTTATTGATGTTATTTGTCTGGACGGCTTTAAGTAAAAAAATTGGTAAG
AAACTCGTTTATTTCTTGGGAATGAGTTCATGGATAATTGCAGCTGCTGGACTCTTTTTCTTACAACCTGGTCAAATAGG
TTTGATGTATGTCATGGCTATCATGGCGGGTGTGGGTGTATCCACAGCTTACTTAGTCCCCTGGTCAATGATTCCCGATG
TGATTGAATTAGACGAACTGCAAACTGGACAACGCCGAGAAGGTATTTTTTACGGCTTTATGGTTTTATTGCAGAAATTT
GGTTTGGCTTTCGGCTTATTTCTGGTAGGTAATGCCTTGCAAGCATCTGGTTTCAAAGAAGCTGTCGCTGGACAAACTAC
TCTACCAATACAACCAGAATCGGCTCTTTTCGCTATCCGCATTGCCGTTGGGCCTTTACCCACCATCTGTTTAATTTTTG
GCTTAGTCTTAACCTATTTCTACCCCATTACCCGTGAAATGCACGCGGAAATTCTGCTAAAACTCCAAGAACGTCAAAAG
CAGAGAGAAACAAATCCAGAGTGA

Upstream 100 bases:

>100_bases
TGATACTCTGACCAAGAAACGTAAAGGTCTGGCATAAGGTAAGTAGGTTTTAGGTGATACTAAAGGCGATCGCAATATTT
TAATATGAGCGCAAGGTATT

Downstream 100 bases:

>100_bases
TAAGTATAGGACTTACGCATGAAAACGAAAGATCAAGGGTTTGGAGAAGGGTATAGGGGTATATAAGTAGTTATTTCATT
CCCATTACCCATTCCAGATG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 487; Mature: 487

Protein sequence:

>487_residues
MNDSAADGYAQKPKNSQKLDLKTKLAYGAGDLGPAITANISIFFLLIFFTNVAGIPAGLAGSVLMIGKIWDAVNDPFVGV
LTDKTKSRRWGRRLPWMLYGAIPFGIFFFLQWIVPRFSSDQGSNVWALFWYYVVIGLISQVFYTVVNLPYTALTPELTQD
YDERTSLNSFRFAFSIGGSILSLILSKVVLSLISDRQQQYIVLAAICTVISVISLYWCVFGVRERVLAFEAKRIQVEESD
SIPFFEQLKIVFSNRPFLFVIGIYLFSWLGVQITASIIPYFVINCMSLPESDVPTTMIAVQGTALLMLFVWTALSKKIGK
KLVYFLGMSSWIIAAAGLFFLQPGQIGLMYVMAIMAGVGVSTAYLVPWSMIPDVIELDELQTGQRREGIFYGFMVLLQKF
GLAFGLFLVGNALQASGFKEAVAGQTTLPIQPESALFAIRIAVGPLPTICLIFGLVLTYFYPITREMHAEILLKLQERQK
QRETNPE

Sequences:

>Translated_487_residues
MNDSAADGYAQKPKNSQKLDLKTKLAYGAGDLGPAITANISIFFLLIFFTNVAGIPAGLAGSVLMIGKIWDAVNDPFVGV
LTDKTKSRRWGRRLPWMLYGAIPFGIFFFLQWIVPRFSSDQGSNVWALFWYYVVIGLISQVFYTVVNLPYTALTPELTQD
YDERTSLNSFRFAFSIGGSILSLILSKVVLSLISDRQQQYIVLAAICTVISVISLYWCVFGVRERVLAFEAKRIQVEESD
SIPFFEQLKIVFSNRPFLFVIGIYLFSWLGVQITASIIPYFVINCMSLPESDVPTTMIAVQGTALLMLFVWTALSKKIGK
KLVYFLGMSSWIIAAAGLFFLQPGQIGLMYVMAIMAGVGVSTAYLVPWSMIPDVIELDELQTGQRREGIFYGFMVLLQKF
GLAFGLFLVGNALQASGFKEAVAGQTTLPIQPESALFAIRIAVGPLPTICLIFGLVLTYFYPITREMHAEILLKLQERQK
QRETNPE
>Mature_487_residues
MNDSAADGYAQKPKNSQKLDLKTKLAYGAGDLGPAITANISIFFLLIFFTNVAGIPAGLAGSVLMIGKIWDAVNDPFVGV
LTDKTKSRRWGRRLPWMLYGAIPFGIFFFLQWIVPRFSSDQGSNVWALFWYYVVIGLISQVFYTVVNLPYTALTPELTQD
YDERTSLNSFRFAFSIGGSILSLILSKVVLSLISDRQQQYIVLAAICTVISVISLYWCVFGVRERVLAFEAKRIQVEESD
SIPFFEQLKIVFSNRPFLFVIGIYLFSWLGVQITASIIPYFVINCMSLPESDVPTTMIAVQGTALLMLFVWTALSKKIGK
KLVYFLGMSSWIIAAAGLFFLQPGQIGLMYVMAIMAGVGVSTAYLVPWSMIPDVIELDELQTGQRREGIFYGFMVLLQKF
GLAFGLFLVGNALQASGFKEAVAGQTTLPIQPESALFAIRIAVGPLPTICLIFGLVLTYFYPITREMHAEILLKLQERQK
QRETNPE

Specific function: Unknown

COG id: COG2211

COG function: function code G; Na+/melibiose symporter and related transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:galactoside symporter (TC 2.A.2) family [H]

Homologues:

Organism=Homo sapiens, GI42713696, Length=498, Percent_Identity=26.5060240963855, Blast_Score=162, Evalue=6e-40,
Organism=Homo sapiens, GI211063479, Length=511, Percent_Identity=25.8317025440313, Blast_Score=154, Evalue=2e-37,
Organism=Homo sapiens, GI122937339, Length=476, Percent_Identity=26.0504201680672, Blast_Score=147, Evalue=2e-35,
Organism=Homo sapiens, GI111378395, Length=416, Percent_Identity=23.7980769230769, Blast_Score=76, Evalue=5e-14,
Organism=Homo sapiens, GI111378391, Length=416, Percent_Identity=23.7980769230769, Blast_Score=76, Evalue=6e-14,
Organism=Homo sapiens, GI111378386, Length=416, Percent_Identity=23.7980769230769, Blast_Score=76, Evalue=9e-14,
Organism=Escherichia coli, GI87082306, Length=483, Percent_Identity=28.1573498964803, Blast_Score=174, Evalue=1e-44,
Organism=Escherichia coli, GI1786466, Length=483, Percent_Identity=27.9503105590062, Blast_Score=162, Evalue=4e-41,
Organism=Escherichia coli, GI145693206, Length=471, Percent_Identity=25.0530785562633, Blast_Score=134, Evalue=1e-32,
Organism=Escherichia coli, GI48994989, Length=481, Percent_Identity=25.987525987526, Blast_Score=130, Evalue=2e-31,
Organism=Escherichia coli, GI1790561, Length=485, Percent_Identity=24.5360824742268, Blast_Score=122, Evalue=5e-29,
Organism=Escherichia coli, GI1787902, Length=480, Percent_Identity=26.875, Blast_Score=121, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI17567067, Length=488, Percent_Identity=20.9016393442623, Blast_Score=80, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016196
- InterPro:   IPR001927
- InterPro:   IPR018043 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 54314; Mature: 54314

Theoretical pI: Translated: 8.73; Mature: 8.73

Prosite motif: PS00872 NA_GALACTOSIDE_SYMP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDSAADGYAQKPKNSQKLDLKTKLAYGAGDLGPAITANISIFFLLIFFTNVAGIPAGLA
CCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCC
GSVLMIGKIWDAVNDPFVGVLTDKTKSRRWGRRLPWMLYGAIPFGIFFFLQWIVPRFSSD
CHHHHHHHHHHHCCCCEEEEECCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCC
QGSNVWALFWYYVVIGLISQVFYTVVNLPYTALTPELTQDYDERTSLNSFRFAFSIGGSI
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCHHHHCHHHHCCCCHHHHHHHHHHHH
LSLILSKVVLSLISDRQQQYIVLAAICTVISVISLYWCVFGVRERVLAFEAKRIQVEESD
HHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCC
SIPFFEQLKIVFSNRPFLFVIGIYLFSWLGVQITASIIPYFVINCMSLPESDVPTTMIAV
CCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEE
QGTALLMLFVWTALSKKIGKKLVYFLGMSSWIIAAAGLFFLQPGQIGLMYVMAIMAGVGV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCC
STAYLVPWSMIPDVIELDELQTGQRREGIFYGFMVLLQKFGLAFGLFLVGNALQASGFKE
CHHEECCHHHCCCHHHHHHCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCHH
AVAGQTTLPIQPESALFAIRIAVGPLPTICLIFGLVLTYFYPITREMHAEILLKLQERQK
HHCCCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QRETNPE
HCCCCCC
>Mature Secondary Structure
MNDSAADGYAQKPKNSQKLDLKTKLAYGAGDLGPAITANISIFFLLIFFTNVAGIPAGLA
CCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCC
GSVLMIGKIWDAVNDPFVGVLTDKTKSRRWGRRLPWMLYGAIPFGIFFFLQWIVPRFSSD
CHHHHHHHHHHHCCCCEEEEECCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCC
QGSNVWALFWYYVVIGLISQVFYTVVNLPYTALTPELTQDYDERTSLNSFRFAFSIGGSI
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCHHHHCHHHHCCCCHHHHHHHHHHHH
LSLILSKVVLSLISDRQQQYIVLAAICTVISVISLYWCVFGVRERVLAFEAKRIQVEESD
HHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCC
SIPFFEQLKIVFSNRPFLFVIGIYLFSWLGVQITASIIPYFVINCMSLPESDVPTTMIAV
CCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEE
QGTALLMLFVWTALSKKIGKKLVYFLGMSSWIIAAAGLFFLQPGQIGLMYVMAIMAGVGV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCC
STAYLVPWSMIPDVIELDELQTGQRREGIFYGFMVLLQKFGLAFGLFLVGNALQASGFKE
CHHEECCHHHCCCHHHHHHCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCHH
AVAGQTTLPIQPESALFAIRIAVGPLPTICLIFGLVLTYFYPITREMHAEILLKLQERQK
HHCCCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QRETNPE
HCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]