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The map label for this gene is cbbY [H]

Identifier: 17231020

GI number: 17231020

Start: 4251208

End: 4251936

Strand: Direct

Name: cbbY [H]

Synonym: alr3528

Alternate gene names: 17231020

Gene position: 4251208-4251936 (Clockwise)

Preceding gene: 17231019

Following gene: 17231021

Centisome position: 66.28

GC content: 43.62

Gene sequence:

>729_bases
ATGAGTTTAAAGGCAATTCTGTTTGATTTCAATGGCGTAATCATTAACGATGAGCGCATCCACCTACAATTGATCGATGA
AATTCTTATTCAAGAAAATCTCCAACCCCAAAAAGTGCAAGAGCGTCAAGCTTCCTTAGGAAGGAGCGATCGCGCTTGTT
TTCAAGAATTGCTAGCAAATCGTGGTAGAGTCGTCAGCGATGATTCTTTAACTCAGTTACTCAACAGTAAAGCTCAAGCC
TACGTGCTGGAAGTGGAGAAATTAGAAAAACTGCCTATATATCCAGGTGTAGAAGACTTGATATATCAAGCGCGTTCCCG
TCATCTCCATTTAGGCATTGTTAGCGGTGCGGTTCGTCAAGAAATCGAACTAGTGCTTAATCATGCCAAACTAGCCGAGT
ACTTCACAGTTATTGTTGCAGGCGACGACATCACCACCAGCAAACCCAAACCAGATGGTTATTTACTAGCAGTGGAACGC
CTAAATCAAGAATATCCCCAATTAAATCTCTTGCCCCAAGAATGCTTGGCAATTGAAGATACCCCAGCAGGTATCGCAGC
CGCTAAACGAGCGCAAATGCAGGTAGTAGGCGTAGCCAATACATACCCCTTCCATATGTTACAACGCTGCTGTAACTGGA
CTGTCGATTATCTGAGTGACTTGGAACTAGAACGAGTCCAAAAAATATTTTCTGGCGGAGAATTTCCGGCGATCGTGAGT
GAGTGTTAA

Upstream 100 bases:

>100_bases
TAGCAACAGATACTAACCAAATAAAAGACAGACAATATATGCCAGCAATAGATAATAATAATTTGGAGGGTCTAGAATCT
CCAGCTTTTGGCATAGTGGC

Downstream 100 bases:

>100_bases
GATATTGTCTGATAGTATGGCGTTGATTAGGTAAGCATAGTTTGATCAACTTACCATTCAGCTATCTAAGGGGAATTAGC
TCAGTTGGTAGAGCGCTGCG

Product: hypothetical protein

Products: beta-D-glucose 6-phosphate

Alternate protein names: NA

Number of amino acids: Translated: 242; Mature: 241

Protein sequence:

>242_residues
MSLKAILFDFNGVIINDERIHLQLIDEILIQENLQPQKVQERQASLGRSDRACFQELLANRGRVVSDDSLTQLLNSKAQA
YVLEVEKLEKLPIYPGVEDLIYQARSRHLHLGIVSGAVRQEIELVLNHAKLAEYFTVIVAGDDITTSKPKPDGYLLAVER
LNQEYPQLNLLPQECLAIEDTPAGIAAAKRAQMQVVGVANTYPFHMLQRCCNWTVDYLSDLELERVQKIFSGGEFPAIVS
EC

Sequences:

>Translated_242_residues
MSLKAILFDFNGVIINDERIHLQLIDEILIQENLQPQKVQERQASLGRSDRACFQELLANRGRVVSDDSLTQLLNSKAQA
YVLEVEKLEKLPIYPGVEDLIYQARSRHLHLGIVSGAVRQEIELVLNHAKLAEYFTVIVAGDDITTSKPKPDGYLLAVER
LNQEYPQLNLLPQECLAIEDTPAGIAAAKRAQMQVVGVANTYPFHMLQRCCNWTVDYLSDLELERVQKIFSGGEFPAIVS
EC
>Mature_241_residues
SLKAILFDFNGVIINDERIHLQLIDEILIQENLQPQKVQERQASLGRSDRACFQELLANRGRVVSDDSLTQLLNSKAQAY
VLEVEKLEKLPIYPGVEDLIYQARSRHLHLGIVSGAVRQEIELVLNHAKLAEYFTVIVAGDDITTSKPKPDGYLLAVERL
NQEYPQLNLLPQECLAIEDTPAGIAAAKRAQMQVVGVANTYPFHMLQRCCNWTVDYLSDLELERVQKIFSGGEFPAIVSE
C

Specific function: Reversible Transformation Of Glucose 6-Phosphate And Beta-Glucose 1-Phosphate (By Similarity). [C]

COG id: COG0637

COG function: function code R; Predicted phosphatase/phosphohexomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family [H]

Homologues:

Organism=Escherichia coli, GI1787576, Length=217, Percent_Identity=27.6497695852535, Blast_Score=71, Evalue=8e-14,
Organism=Escherichia coli, GI1789787, Length=171, Percent_Identity=28.0701754385965, Blast_Score=64, Evalue=7e-12,
Organism=Escherichia coli, GI1789046, Length=194, Percent_Identity=25.7731958762887, Blast_Score=61, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006402
- InterPro:   IPR005833 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: 5.4.2.6

Molecular weight: Translated: 27232; Mature: 27100

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLKAILFDFNGVIINDERIHLQLIDEILIQENLQPQKVQERQASLGRSDRACFQELLAN
CCCEEEEEECCCEEECCCEEHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHC
RGRVVSDDSLTQLLNSKAQAYVLEVEKLEKLPIYPGVEDLIYQARSRHLHLGIVSGAVRQ
CCCEECCHHHHHHHHCCHHEEEHHHHHHHCCCCCCCHHHHHHHHHHCEEEEEHHHHHHHH
EIELVLNHAKLAEYFTVIVAGDDITTSKPKPDGYLLAVERLNQEYPQLNLLPQECLAIED
HHHHHHHHHHHHHHEEEEEECCCCCCCCCCCCCEEEEHHHHCCCCCCCCCCHHHHHEECC
TPAGIAAAKRAQMQVVGVANTYPFHMLQRCCNWTVDYLSDLELERVQKIFSGGEFPAIVS
CCCHHHHHHHHHEEEEEECCCCHHHHHHHHHCCHHHHHHCCCHHHHHHHHCCCCCCHHHC
EC
CC
>Mature Secondary Structure 
SLKAILFDFNGVIINDERIHLQLIDEILIQENLQPQKVQERQASLGRSDRACFQELLAN
CCEEEEEECCCEEECCCEEHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHC
RGRVVSDDSLTQLLNSKAQAYVLEVEKLEKLPIYPGVEDLIYQARSRHLHLGIVSGAVRQ
CCCEECCHHHHHHHHCCHHEEEHHHHHHHCCCCCCCHHHHHHHHHHCEEEEEHHHHHHHH
EIELVLNHAKLAEYFTVIVAGDDITTSKPKPDGYLLAVERLNQEYPQLNLLPQECLAIED
HHHHHHHHHHHHHHEEEEEECCCCCCCCCCCCCEEEEHHHHCCCCCCCCCCHHHHHEECC
TPAGIAAAKRAQMQVVGVANTYPFHMLQRCCNWTVDYLSDLELERVQKIFSGGEFPAIVS
CCCHHHHHHHHHEEEEEECCCCHHHHHHHHHCCHHHHHHCCCHHHHHHHHCCCCCCHHHC
EC
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: beta-D-glucose 1-phosphate

Specific reaction: beta-D-glucose 1-phosphate = beta-D-glucose 6-phosphate

General reaction: Group transfer (intramolecular phosphate group isomerization [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA