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The map label for this gene is mshA [H]

Identifier: 17230862

GI number: 17230862

Start: 4078966

End: 4080255

Strand: Direct

Name: mshA [H]

Synonym: alr3370

Alternate gene names: 17230862

Gene position: 4078966-4080255 (Clockwise)

Preceding gene: 17230861

Following gene: 17230864

Centisome position: 63.6

GC content: 46.98

Gene sequence:

>1290_bases
GTGAAGCTCACTATGTTCCAAAATAAAAAACATCGGATCGCACTTATTTCTGTTTCTGGAGATCCAGCCGTTGAAATAGG
TCAAGAAGAAGCCGGTGGTCAGAACGTATATGTTCGAGAAGTAGGCTATGCACTAGCCGAACAAGGTTGGCAAGTTGATA
TGTTCACTCGCCGTATCAGTCCCGACCAGGCCGAGATTGTCCAACATAGTCCTAATTGCCGCACTATCCGCTTACAAGCG
GGGCCGGTTGAATTTATCGGACGTGATCACGTATTTGATTATTTACCGGAATTTGTTGCCGAATTCCAACGCTTCCAAAA
GCGCCAAGGTTATAACTATCAACTCATTCACACAAATTACTGGTTGTCATCTTGGGTGGGAATGCAACTGAAAAAGCAAC
AACCCTTGGTGTTGGTGCATACATACCACTCATTAGGAGCAATCAAATATCAAACGATCGCAGATATACCCGCCATTGCG
AATCAGCGATTAGCTATAGAAAAAGCTTGTTTAGAGAGTGTAGACACAGTAGTTGCCACCAGCCCCCAAGAACAGCAACA
TATGCGCGCCCTGGTTTCTAAGAAGGGACGCATAGAGATGATTCCTTGCGGGACTGACATTAATAACTTCGGAAACATTG
AAAAGTCGGCTGCACGGGAAAAACTGGGAATTGAGCCTGATGCCAAGATGGTATTTTATGTAGGTCGTTTTGATCCCCGT
AAAGGCATAGAAACCTTAGTCAGAGCGGTTGCTCAGTCTAGGTTGAGAGGTGAAGCAAACCTCCAGTTAGTAATTGGTGG
TGGTAGCCGTCCTGGTCAAAGTGATGGCAGAGAGCGCGATCGCATTGCGAATATTGTGGCTGAACTAGAACTGAACGATT
GCACCACCTTCGCTGGTCGCCTAGATCATGAAATCCTCCCTTACTACTACGCTGCGGCTGATGTTTGCGTTGTCCCCAGT
CACTACGAACCCTTTGGTTTAGTTGCTATTGAAGCGATGGCTAGCAAAACTCCCGTAATCGCCAGTAATGTAGGTGGATT
GCAATTTACAGTAGTTCCAGAAGTCACAGGTTTACTTGCACCTCCACAAGATGAGTCAGCTTTTGCTACAGCCATAGACC
GCATATTAGCCAACCCAACTTGGCGAGATCAGCTAGGCACAGCCGCCCGCCAGCGAGTGGAAACCACCTTCAGCTGGGCC
GGTGTAGCATCCCAATTGAGTCAGCTATACACTCATCTGTTAACTCAAAATGCGCCAGAAAAGAAGGAAAAAGAGGCTGT
TGCAGCGTAG

Upstream 100 bases:

>100_bases
TGGCTGGTAGCTTTACGCTTCGTTTTACCTGCCCTCGACTAGAGGGATGGATACTTATGTCCTAAATTCTGGTGTCTGAG
GAAGAAGTAGTTACCTTGAG

Downstream 100 bases:

>100_bases
TTAAAGTGAGTTTGGTGGAACCTAACCCCAATCCGGTTCCAAATTTAGGGTGCGTCAGTGCGATATAACCTAAATATACT
CAGAAATTACTCATACTGAC

Product: hypothetical protein

Products: NA

Alternate protein names: N-acetylglucosamine-inositol-phosphate N-acetylglucosaminyltransferase; GlcNAc-Ins-P N-acetylglucosaminyltransferase [H]

Number of amino acids: Translated: 429; Mature: 429

Protein sequence:

>429_residues
MKLTMFQNKKHRIALISVSGDPAVEIGQEEAGGQNVYVREVGYALAEQGWQVDMFTRRISPDQAEIVQHSPNCRTIRLQA
GPVEFIGRDHVFDYLPEFVAEFQRFQKRQGYNYQLIHTNYWLSSWVGMQLKKQQPLVLVHTYHSLGAIKYQTIADIPAIA
NQRLAIEKACLESVDTVVATSPQEQQHMRALVSKKGRIEMIPCGTDINNFGNIEKSAAREKLGIEPDAKMVFYVGRFDPR
KGIETLVRAVAQSRLRGEANLQLVIGGGSRPGQSDGRERDRIANIVAELELNDCTTFAGRLDHEILPYYYAAADVCVVPS
HYEPFGLVAIEAMASKTPVIASNVGGLQFTVVPEVTGLLAPPQDESAFATAIDRILANPTWRDQLGTAARQRVETTFSWA
GVASQLSQLYTHLLTQNAPEKKEKEAVAA

Sequences:

>Translated_429_residues
MKLTMFQNKKHRIALISVSGDPAVEIGQEEAGGQNVYVREVGYALAEQGWQVDMFTRRISPDQAEIVQHSPNCRTIRLQA
GPVEFIGRDHVFDYLPEFVAEFQRFQKRQGYNYQLIHTNYWLSSWVGMQLKKQQPLVLVHTYHSLGAIKYQTIADIPAIA
NQRLAIEKACLESVDTVVATSPQEQQHMRALVSKKGRIEMIPCGTDINNFGNIEKSAAREKLGIEPDAKMVFYVGRFDPR
KGIETLVRAVAQSRLRGEANLQLVIGGGSRPGQSDGRERDRIANIVAELELNDCTTFAGRLDHEILPYYYAAADVCVVPS
HYEPFGLVAIEAMASKTPVIASNVGGLQFTVVPEVTGLLAPPQDESAFATAIDRILANPTWRDQLGTAARQRVETTFSWA
GVASQLSQLYTHLLTQNAPEKKEKEAVAA
>Mature_429_residues
MKLTMFQNKKHRIALISVSGDPAVEIGQEEAGGQNVYVREVGYALAEQGWQVDMFTRRISPDQAEIVQHSPNCRTIRLQA
GPVEFIGRDHVFDYLPEFVAEFQRFQKRQGYNYQLIHTNYWLSSWVGMQLKKQQPLVLVHTYHSLGAIKYQTIADIPAIA
NQRLAIEKACLESVDTVVATSPQEQQHMRALVSKKGRIEMIPCGTDINNFGNIEKSAAREKLGIEPDAKMVFYVGRFDPR
KGIETLVRAVAQSRLRGEANLQLVIGGGSRPGQSDGRERDRIANIVAELELNDCTTFAGRLDHEILPYYYAAADVCVVPS
HYEPFGLVAIEAMASKTPVIASNVGGLQFTVVPEVTGLLAPPQDESAFATAIDRILANPTWRDQLGTAARQRVETTFSWA
GVASQLSQLYTHLLTQNAPEKKEKEAVAA

Specific function: Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 1 family. MshA subfamily [H]

Homologues:

Organism=Homo sapiens, GI14861836, Length=209, Percent_Identity=28.7081339712919, Blast_Score=71, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001296
- InterPro:   IPR017814
- InterPro:   IPR013534 [H]

Pfam domain/function: PF08323 Glyco_transf_5; PF00534 Glycos_transf_1 [H]

EC number: =2.4.1.250 [H]

Molecular weight: Translated: 47665; Mature: 47665

Theoretical pI: Translated: 6.85; Mature: 6.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLTMFQNKKHRIALISVSGDPAVEIGQEEAGGQNVYVREVGYALAEQGWQVDMFTRRIS
CEEEEEECCCCEEEEEEECCCCCEEECCCCCCCCEEEHHHHHHHHHHCCCEEEEHHHCCC
PDQAEIVQHSPNCRTIRLQAGPVEFIGRDHVFDYLPEFVAEFQRFQKRQGYNYQLIHTNY
CCHHHHHHCCCCCCEEEEECCCHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECC
WLSSWVGMQLKKQQPLVLVHTYHSLGAIKYQTIADIPAIANQRLAIEKACLESVDTVVAT
HHHHHHCCEECCCCCEEEEEECCCCCCEEEHHHHCCHHHHCCHHHHHHHHHHHHHHHHCC
SPQEQQHMRALVSKKGRIEMIPCGTDINNFGNIEKSAAREKLGIEPDAKMVFYVGRFDPR
CCHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCHHHHHHHHCCCCCCCEEEEEEECCCHH
KGIETLVRAVAQSRLRGEANLQLVIGGGSRPGQSDGRERDRIANIVAELELNDCTTFAGR
HHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHEECCCHHHHHHH
LDHEILPYYYAAADVCVVPSHYEPFGLVAIEAMASKTPVIASNVGGLQFTVVPEVTGLLA
CCCHHHHHHHHCCCEEEECCCCCCCHHHEEHHHHCCCCEEEECCCCEEEEECCCHHHCCC
PPQDESAFATAIDRILANPTWRDQLGTAARQRVETTFSWAGVASQLSQLYTHLLTQNAPE
CCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
KKEKEAVAA
HHHHHHCCC
>Mature Secondary Structure
MKLTMFQNKKHRIALISVSGDPAVEIGQEEAGGQNVYVREVGYALAEQGWQVDMFTRRIS
CEEEEEECCCCEEEEEEECCCCCEEECCCCCCCCEEEHHHHHHHHHHCCCEEEEHHHCCC
PDQAEIVQHSPNCRTIRLQAGPVEFIGRDHVFDYLPEFVAEFQRFQKRQGYNYQLIHTNY
CCHHHHHHCCCCCCEEEEECCCHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECC
WLSSWVGMQLKKQQPLVLVHTYHSLGAIKYQTIADIPAIANQRLAIEKACLESVDTVVAT
HHHHHHCCEECCCCCEEEEEECCCCCCEEEHHHHCCHHHHCCHHHHHHHHHHHHHHHHCC
SPQEQQHMRALVSKKGRIEMIPCGTDINNFGNIEKSAAREKLGIEPDAKMVFYVGRFDPR
CCHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCHHHHHHHHCCCCCCCEEEEEEECCCHH
KGIETLVRAVAQSRLRGEANLQLVIGGGSRPGQSDGRERDRIANIVAELELNDCTTFAGR
HHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHEECCCHHHHHHH
LDHEILPYYYAAADVCVVPSHYEPFGLVAIEAMASKTPVIASNVGGLQFTVVPEVTGLLA
CCCHHHHHHHHCCCEEEECCCCCCCHHHEEHHHHCCCCEEEECCCCEEEEECCCHHHCCC
PPQDESAFATAIDRILANPTWRDQLGTAARQRVETTFSWAGVASQLSQLYTHLLTQNAPE
CCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
KKEKEAVAA
HHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12840036 [H]