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The map label for this gene is nlpD [C]

Identifier: 17230845

GI number: 17230845

Start: 4056687

End: 4058969

Strand: Direct

Name: nlpD [C]

Synonym: alr3353

Alternate gene names: 17230845

Gene position: 4056687-4058969 (Clockwise)

Preceding gene: 17230844

Following gene: 17230847

Centisome position: 63.25

GC content: 48.05

Gene sequence:

>2283_bases
GTGAAGGCTGTGTTGAAAAATACCCCTACCCGCGATGATGCCCCGGCAGATCAGTTCAACGTAGTAAACAATCAAGCTAA
TCGCCGGGCGCGGAGACAAGCGGCAATGATTGGCCTAGCCATATCAATGGGAGCAACCAGCCTTTTGGTGACTCGACAAA
GCGATCAAGCCCAAGCGGCTGCGCCTGTGGGTAGCCAAAAGGCAGCCTCAAGTATCCCTACTGCTACTGATTCCGAACTG
AAATTAGCTGCCACGCAACTGGGAACTTCCAGAGTTCTAGCGACCAGCGTGCCGGAGAACCCAGTCATCATGGAACCAAC
AGCAGTTTCACAGTTGCCTGGACTAGAAGCTAAGTGGCAAATTTTGTCCAGTGGAATGTCTGTGCAGCTTCCTGCATCAG
AGAATATTACTAAAAACATCGCCTTTCATAAAACTACTATCAACCACCAATCTCAACTGGCACAAGGGGAACAAACAACC
AAGCCAGTAAAAGAGATAGCAGCACAACTGAACAACGTTAACGGCGTGACTGCTGGGCAAAATACATTACCAACGACTCA
ACCACAAGCACTAGCTGATGACACAACCGCTAGCGATGGTATTAATGCCCAACTAAAAGCGCAGCAAGAATTTGCGCTCA
GTCGTTTACAAGAGAAATCGAGCCGTTTAAGAAAAAGTCTGGCGGAGTTGCGGTCTGAGGAGTCAAAAGATTTATCAAAA
GCTACTATTGGGTTAACACAGCCCACAAGTTTAGCTAATCAACTACCACCATTGACCACAAATGGTACAGTAATTGAGCA
GCAGTTAACAGTGGCTAATGGTAGCCAAGATAGCCTGGCAACGACAATCAAGCAGCCACAGCCGATTAACATACAAGTAC
AGCCATTAACTGAAACATCAGCATCAACTGCAAATACTTACGAAGTTAAGCCCGGAGATACCCTAGCGGCGATCGCCAGC
AGATACAACACTTCCGTTGCAGAATTAGTAAAAGTTAACAATCTCAGCAATCCTAACCAACTAAAAATCAGCCAACAACT
GATTATTCCCAGTGCTATAGACAGCAGCAGCACCATAGCTCAAGCACCAGCAATAATTAGCTCTAACAGAGTGCAGTACC
CTGGCACTCCTACAGTACCTAACTTCCCTGTAGATACTGCTAGAGTCAATCCCAGCTTGCCAGTTGCACAGCCCCCATCT
ATAGCTAACAACGACAGTGTACCTATCACTGTGCCAACACCAGGCGCTGATAGTGAAACACCAGTTGATACAATTGTTCC
ACTGGAATCAGCTTCAGCTCCTGCTGAAACCCAAGGGGTGGGTGGTAATGTACCAATACCCAAAGCCTTTATTGAAATAC
AGCGCCCTCAACAACCTGGAAAGAGAGCAGCCAGAGCGAAAGGCGATCGCTTACGTAGCTTACAAGCAGAAATCCAAAGA
TTACAGGCAAAATATCGGGATCAACAGACTGGCAATACACCTGTACCAGTAGTTGCCAATCAAAACAACAACACTGCCAT
ACCAATTCCCGTTACTAGCCCCAACAACTTTGCAGTAACTAGACCAATTTCCAGACAGCAAGAAATCGCCGTACCAATTG
CTGTACCCACACCATTAGCACCAAACGACAGTAACCATCCTGTTAAGCCTCAATTCCGGGCTACGCTCCCTGTTAATGAA
GCATTAAATCCAGAATTCCTGCCTAACAACGCCCCTCAGAATCCTTCCGTTAGAAGGGTAGCTACACCTCCTGTCCGTCT
CAATGCTTCTGAGTCGCTAGGAAGAATGCGAGGAACTACTGTGTCTCCAAAATTGCCACCTTTGGCAGCAGTAGACCAGT
ACTTACCACAAGCAATCGATGAAAGCGTGCCTCCCCCATCAGACTCCACCACAGCATTCATTTGGCCAGCAAAAGGCGTA
TTAACGTCTGGTTACGGCTGGCGCTGGGGAAGAATGCACAGAGGTATTGACATCGCTGCTCCGGTTGGTACGCCAGTGTT
CGCCGCAGCCGATGGCGTTGTAGAGAAATCTGGTTGGAATAGAGGCGGTTACGGTAATCTAGTGGATATTCGTCACCCCG
ATGGCAGCTTGACCCGTTACGCACACAACAGCAGGCTTTTAGTACAAGCAGGTCAACAAGTGCGTCAAGGGCAGCAAATC
GCCGCTATGGGTAGCACAGGCTTTAGCACAGGGCCCCACACTCACTTTGAAATCCATAAAACTGGCAAAGGAGCAATAAA
TCCTATAGCGATGCTACCAGCCACCACCAGCAACCGCATATAG

Upstream 100 bases:

>100_bases
GTGATCTAAATCATTGACTAGTATCCGACCGAAAAATCGAGGTCAGTTAAGCGCTAGTGATCATAGGAGGTCGTCTTTGA
AACGAGCATTGAAAAAAAGA

Downstream 100 bases:

>100_bases
TTCCTGGCTATCTTCGACTGAATAATTTCTTTGTTTGTAGAGGGGGGTTAACGTAACTCCCCTCTTTTATTTTTTAATTA
TCTTCGTCTCCCGTCTCAGC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 760; Mature: 760

Protein sequence:

>760_residues
MKAVLKNTPTRDDAPADQFNVVNNQANRRARRQAAMIGLAISMGATSLLVTRQSDQAQAAAPVGSQKAASSIPTATDSEL
KLAATQLGTSRVLATSVPENPVIMEPTAVSQLPGLEAKWQILSSGMSVQLPASENITKNIAFHKTTINHQSQLAQGEQTT
KPVKEIAAQLNNVNGVTAGQNTLPTTQPQALADDTTASDGINAQLKAQQEFALSRLQEKSSRLRKSLAELRSEESKDLSK
ATIGLTQPTSLANQLPPLTTNGTVIEQQLTVANGSQDSLATTIKQPQPINIQVQPLTETSASTANTYEVKPGDTLAAIAS
RYNTSVAELVKVNNLSNPNQLKISQQLIIPSAIDSSSTIAQAPAIISSNRVQYPGTPTVPNFPVDTARVNPSLPVAQPPS
IANNDSVPITVPTPGADSETPVDTIVPLESASAPAETQGVGGNVPIPKAFIEIQRPQQPGKRAARAKGDRLRSLQAEIQR
LQAKYRDQQTGNTPVPVVANQNNNTAIPIPVTSPNNFAVTRPISRQQEIAVPIAVPTPLAPNDSNHPVKPQFRATLPVNE
ALNPEFLPNNAPQNPSVRRVATPPVRLNASESLGRMRGTTVSPKLPPLAAVDQYLPQAIDESVPPPSDSTTAFIWPAKGV
LTSGYGWRWGRMHRGIDIAAPVGTPVFAAADGVVEKSGWNRGGYGNLVDIRHPDGSLTRYAHNSRLLVQAGQQVRQGQQI
AAMGSTGFSTGPHTHFEIHKTGKGAINPIAMLPATTSNRI

Sequences:

>Translated_760_residues
MKAVLKNTPTRDDAPADQFNVVNNQANRRARRQAAMIGLAISMGATSLLVTRQSDQAQAAAPVGSQKAASSIPTATDSEL
KLAATQLGTSRVLATSVPENPVIMEPTAVSQLPGLEAKWQILSSGMSVQLPASENITKNIAFHKTTINHQSQLAQGEQTT
KPVKEIAAQLNNVNGVTAGQNTLPTTQPQALADDTTASDGINAQLKAQQEFALSRLQEKSSRLRKSLAELRSEESKDLSK
ATIGLTQPTSLANQLPPLTTNGTVIEQQLTVANGSQDSLATTIKQPQPINIQVQPLTETSASTANTYEVKPGDTLAAIAS
RYNTSVAELVKVNNLSNPNQLKISQQLIIPSAIDSSSTIAQAPAIISSNRVQYPGTPTVPNFPVDTARVNPSLPVAQPPS
IANNDSVPITVPTPGADSETPVDTIVPLESASAPAETQGVGGNVPIPKAFIEIQRPQQPGKRAARAKGDRLRSLQAEIQR
LQAKYRDQQTGNTPVPVVANQNNNTAIPIPVTSPNNFAVTRPISRQQEIAVPIAVPTPLAPNDSNHPVKPQFRATLPVNE
ALNPEFLPNNAPQNPSVRRVATPPVRLNASESLGRMRGTTVSPKLPPLAAVDQYLPQAIDESVPPPSDSTTAFIWPAKGV
LTSGYGWRWGRMHRGIDIAAPVGTPVFAAADGVVEKSGWNRGGYGNLVDIRHPDGSLTRYAHNSRLLVQAGQQVRQGQQI
AAMGSTGFSTGPHTHFEIHKTGKGAINPIAMLPATTSNRI
>Mature_760_residues
MKAVLKNTPTRDDAPADQFNVVNNQANRRARRQAAMIGLAISMGATSLLVTRQSDQAQAAAPVGSQKAASSIPTATDSEL
KLAATQLGTSRVLATSVPENPVIMEPTAVSQLPGLEAKWQILSSGMSVQLPASENITKNIAFHKTTINHQSQLAQGEQTT
KPVKEIAAQLNNVNGVTAGQNTLPTTQPQALADDTTASDGINAQLKAQQEFALSRLQEKSSRLRKSLAELRSEESKDLSK
ATIGLTQPTSLANQLPPLTTNGTVIEQQLTVANGSQDSLATTIKQPQPINIQVQPLTETSASTANTYEVKPGDTLAAIAS
RYNTSVAELVKVNNLSNPNQLKISQQLIIPSAIDSSSTIAQAPAIISSNRVQYPGTPTVPNFPVDTARVNPSLPVAQPPS
IANNDSVPITVPTPGADSETPVDTIVPLESASAPAETQGVGGNVPIPKAFIEIQRPQQPGKRAARAKGDRLRSLQAEIQR
LQAKYRDQQTGNTPVPVVANQNNNTAIPIPVTSPNNFAVTRPISRQQEIAVPIAVPTPLAPNDSNHPVKPQFRATLPVNE
ALNPEFLPNNAPQNPSVRRVATPPVRLNASESLGRMRGTTVSPKLPPLAAVDQYLPQAIDESVPPPSDSTTAFIWPAKGV
LTSGYGWRWGRMHRGIDIAAPVGTPVFAAADGVVEKSGWNRGGYGNLVDIRHPDGSLTRYAHNSRLLVQAGQQVRQGQQI
AAMGSTGFSTGPHTHFEIHKTGKGAINPIAMLPATTSNRI

Specific function: May Be Involved In Stationary-Phase Survival. [C]

COG id: COG0739

COG function: function code M; Membrane proteins related to metalloendopeptidases

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M23B family [H]

Homologues:

Organism=Escherichia coli, GI1789099, Length=119, Percent_Identity=45.3781512605042, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI87082174, Length=122, Percent_Identity=42.6229508196721, Blast_Score=90, Evalue=6e-19,
Organism=Escherichia coli, GI87081989, Length=106, Percent_Identity=47.1698113207547, Blast_Score=89, Evalue=1e-18,
Organism=Escherichia coli, GI87082297, Length=121, Percent_Identity=39.6694214876033, Blast_Score=79, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011055
- InterPro:   IPR007340
- InterPro:   IPR016047
- InterPro:   IPR002886 [H]

Pfam domain/function: PF04225 OapA; PF01551 Peptidase_M23 [H]

EC number: NA

Molecular weight: Translated: 80571; Mature: 80571

Theoretical pI: Translated: 10.25; Mature: 10.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAVLKNTPTRDDAPADQFNVVNNQANRRARRQAAMIGLAISMGATSLLVTRQSDQAQAA
CCCCCCCCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHH
APVGSQKAASSIPTATDSELKLAATQLGTSRVLATSVPENPVIMEPTAVSQLPGLEAKWQ
CCCCCHHHHHCCCCCCCCCEEEHHHHCCCCEEEEECCCCCCEEECCCHHHHCCCCCHHHH
ILSSGMSVQLPASENITKNIAFHKTTINHQSQLAQGEQTTKPVKEIAAQLNNVNGVTAGQ
HHHCCCEEEECCCCCCHHCEEEEEEECCHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCC
NTLPTTQPQALADDTTASDGINAQLKAQQEFALSRLQEKSSRLRKSLAELRSEESKDLSK
CCCCCCCCCHHCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ATIGLTQPTSLANQLPPLTTNGTVIEQQLTVANGSQDSLATTIKQPQPINIQVQPLTETS
HEECCCCCHHHHHHCCCCCCCCEEEEEEEEECCCCCHHHHHHHCCCCCCEEEEEECCCCC
ASTANTYEVKPGDTLAAIASRYNTSVAELVKVNNLSNPNQLKISQQLIIPSAIDSSSTIA
CCCCCEEEECCCCHHHHHHHHHCCHHHHHHHHCCCCCCCEEEEEHEEECCCCCCCCCHHH
QAPAIISSNRVQYPGTPTVPNFPVDTARVNPSLPVAQPPSIANNDSVPITVPTPGADSET
HCCHHHCCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCC
PVDTIVPLESASAPAETQGVGGNVPIPKAFIEIQRPQQPGKRAARAKGDRLRSLQAEIQR
CCCEEEECCCCCCCCHHCCCCCCCCCCHHHHEECCCCCCHHHHHHHHHHHHHHHHHHHHH
LQAKYRDQQTGNTPVPVVANQNNNTAIPIPVTSPNNFAVTRPISRQQEIAVPIAVPTPLA
HHHHHHHCCCCCCCCCEEEECCCCEEEEEEECCCCCEEEECCCCCCCCEEEEEEECCCCC
PNDSNHPVKPQFRATLPVNEALNPEFLPNNAPQNPSVRRVATPPVRLNASESLGRMRGTT
CCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCEEEECCCEEECCHHHHHHHCCCC
VSPKLPPLAAVDQYLPQAIDESVPPPSDSTTAFIWPAKGVLTSGYGWRWGRMHRGIDIAA
CCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCEECCCCCCHHHHCCCEEEEC
PVGTPVFAAADGVVEKSGWNRGGYGNLVDIRHPDGSLTRYAHNSRLLVQAGQQVRQGQQI
CCCCCHHHHCCCCEECCCCCCCCCCCEEEEECCCCCEEEEECCCEEEEHHHHHHHCCCEE
AAMGSTGFSTGPHTHFEIHKTGKGAINPIAMLPATTSNRI
EEECCCCCCCCCCCEEEEEECCCCCCCCEEEECCCCCCCC
>Mature Secondary Structure
MKAVLKNTPTRDDAPADQFNVVNNQANRRARRQAAMIGLAISMGATSLLVTRQSDQAQAA
CCCCCCCCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHH
APVGSQKAASSIPTATDSELKLAATQLGTSRVLATSVPENPVIMEPTAVSQLPGLEAKWQ
CCCCCHHHHHCCCCCCCCCEEEHHHHCCCCEEEEECCCCCCEEECCCHHHHCCCCCHHHH
ILSSGMSVQLPASENITKNIAFHKTTINHQSQLAQGEQTTKPVKEIAAQLNNVNGVTAGQ
HHHCCCEEEECCCCCCHHCEEEEEEECCHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCC
NTLPTTQPQALADDTTASDGINAQLKAQQEFALSRLQEKSSRLRKSLAELRSEESKDLSK
CCCCCCCCCHHCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ATIGLTQPTSLANQLPPLTTNGTVIEQQLTVANGSQDSLATTIKQPQPINIQVQPLTETS
HEECCCCCHHHHHHCCCCCCCCEEEEEEEEECCCCCHHHHHHHCCCCCCEEEEEECCCCC
ASTANTYEVKPGDTLAAIASRYNTSVAELVKVNNLSNPNQLKISQQLIIPSAIDSSSTIA
CCCCCEEEECCCCHHHHHHHHHCCHHHHHHHHCCCCCCCEEEEEHEEECCCCCCCCCHHH
QAPAIISSNRVQYPGTPTVPNFPVDTARVNPSLPVAQPPSIANNDSVPITVPTPGADSET
HCCHHHCCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCC
PVDTIVPLESASAPAETQGVGGNVPIPKAFIEIQRPQQPGKRAARAKGDRLRSLQAEIQR
CCCEEEECCCCCCCCHHCCCCCCCCCCHHHHEECCCCCCHHHHHHHHHHHHHHHHHHHHH
LQAKYRDQQTGNTPVPVVANQNNNTAIPIPVTSPNNFAVTRPISRQQEIAVPIAVPTPLA
HHHHHHHCCCCCCCCCEEEECCCCEEEEEEECCCCCEEEECCCCCCCCEEEEEEECCCCC
PNDSNHPVKPQFRATLPVNEALNPEFLPNNAPQNPSVRRVATPPVRLNASESLGRMRGTT
CCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCEEEECCCEEECCHHHHHHHCCCC
VSPKLPPLAAVDQYLPQAIDESVPPPSDSTTAFIWPAKGVLTSGYGWRWGRMHRGIDIAA
CCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCEECCCCCCHHHHCCCEEEEC
PVGTPVFAAADGVVEKSGWNRGGYGNLVDIRHPDGSLTRYAHNSRLLVQAGQQVRQGQQI
CCCCCHHHHCCCCEECCCCCCCCCCCEEEEECCCCCEEEEECCCEEEEHHHHHHHCCCEE
AAMGSTGFSTGPHTHFEIHKTGKGAINPIAMLPATTSNRI
EEECCCCCCCCCCCEEEEEECCCCCCCCEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]