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The map label for this gene is 17230842

Identifier: 17230842

GI number: 17230842

Start: 4052475

End: 4053392

Strand: Direct

Name: 17230842

Synonym: alr3350

Alternate gene names: NA

Gene position: 4052475-4053392 (Clockwise)

Preceding gene: 17230837

Following gene: 17230843

Centisome position: 63.18

GC content: 43.9

Gene sequence:

>918_bases
ATGGAACTGCCAATTATTTATCACCCAGATTATGTTGCACCATTGCCTGAAGGACATCGCTTTCCGATGGCAAAATTCAA
AAAACTCTATGAATTGCTGTTAAGTGATGATGTAGCACAAACAGAGCAATTTTATACCCCAACCCTTCCACCCCTAGAGT
TAATCGAGTTAGTTCACACCCCAGACTACGTGCGGTCTTACTGCGAAGGTACACTAGATACCAAAGCACAACGTCGAATC
GGTTTACCTTGGAGTCCAGCACTAGCAAATCGTACCTGTATAGCGGTGGGTGGAACAATACTTACGGCGCAGTTAGCACT
CAGTCAAGGTTTAGCTTGCAATACGGCTGGCGGTACTCATCACGCTTTTCCTAGTTATGGTTCTGGTTTTTGTATTTTCA
ACGATTTAGCGATCGCCTCTCGTGTCCTCCAACAACAGCAAATAGTCCAAAAAATCCTCATTGTCGATTTGGATGTTCAT
CAAGGAGATGGTACAGCTTTTATTTTCCAAGATGATGACAGTGTTTTCACCTTCTCGATGCACTGCGAAATTAACTTCCC
AGGAACCAAGCAACACAGTGATTTAGATGTTCCCTTACCAGTAGGAATGGAGGATGATGCTTACCTACAAACCTTGGCAA
GTTATTTACCAGATTTGTTATCTGAGATCAAGCCTGACTTAGTATTATACGATGCTGGTGTTGATCCACATATAGGCGAT
CGCTTAGGTAAACTAGCTTTAACTGACACTGGCTTATTCCGCCGAGAAATGCAGGTTTTAACTACCTGTGTCAGTGCTGG
CTATCCAGTCGCCTGCGTAATTGGTGGCGGTTACGCTGATGATATGACATCCCTAGTTTGGCGACATTCCCTAGTACATC
GTGCCGCTAGTCAAGTCTATCGCCAATACAAGCTTTAA

Upstream 100 bases:

>100_bases
CTACCAAGCAATCTCTCATATATGGGCGATCGCCTAGAATTTCTCTGCTCAACATAGAATGTTTAGGCATATTCAGCACC
AGTCTGGGAAAATAAATAAC

Downstream 100 bases:

>100_bases
TAGATCATTAAATAATTAGACATTTCATGAGAATATAGATGACATCAGAATTTCTCATCTAGATCAAACATTAGTATTGA
GTCATCAATAATTAATTGTG

Product: histone deacetylase/AcuC/AphA family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 305; Mature: 305

Protein sequence:

>305_residues
MELPIIYHPDYVAPLPEGHRFPMAKFKKLYELLLSDDVAQTEQFYTPTLPPLELIELVHTPDYVRSYCEGTLDTKAQRRI
GLPWSPALANRTCIAVGGTILTAQLALSQGLACNTAGGTHHAFPSYGSGFCIFNDLAIASRVLQQQQIVQKILIVDLDVH
QGDGTAFIFQDDDSVFTFSMHCEINFPGTKQHSDLDVPLPVGMEDDAYLQTLASYLPDLLSEIKPDLVLYDAGVDPHIGD
RLGKLALTDTGLFRREMQVLTTCVSAGYPVACVIGGGYADDMTSLVWRHSLVHRAASQVYRQYKL

Sequences:

>Translated_305_residues
MELPIIYHPDYVAPLPEGHRFPMAKFKKLYELLLSDDVAQTEQFYTPTLPPLELIELVHTPDYVRSYCEGTLDTKAQRRI
GLPWSPALANRTCIAVGGTILTAQLALSQGLACNTAGGTHHAFPSYGSGFCIFNDLAIASRVLQQQQIVQKILIVDLDVH
QGDGTAFIFQDDDSVFTFSMHCEINFPGTKQHSDLDVPLPVGMEDDAYLQTLASYLPDLLSEIKPDLVLYDAGVDPHIGD
RLGKLALTDTGLFRREMQVLTTCVSAGYPVACVIGGGYADDMTSLVWRHSLVHRAASQVYRQYKL
>Mature_305_residues
MELPIIYHPDYVAPLPEGHRFPMAKFKKLYELLLSDDVAQTEQFYTPTLPPLELIELVHTPDYVRSYCEGTLDTKAQRRI
GLPWSPALANRTCIAVGGTILTAQLALSQGLACNTAGGTHHAFPSYGSGFCIFNDLAIASRVLQQQQIVQKILIVDLDVH
QGDGTAFIFQDDDSVFTFSMHCEINFPGTKQHSDLDVPLPVGMEDDAYLQTLASYLPDLLSEIKPDLVLYDAGVDPHIGD
RLGKLALTDTGLFRREMQVLTTCVSAGYPVACVIGGGYADDMTSLVWRHSLVHRAASQVYRQYKL

Specific function: Putative deacetylase [H]

COG id: COG0123

COG function: function code BQ; Deacetylases, including yeast histone deacetylase and acetoin utilization protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the histone deacetylase family [H]

Homologues:

Organism=Homo sapiens, GI217272877, Length=299, Percent_Identity=30.4347826086957, Blast_Score=130, Evalue=1e-30,
Organism=Homo sapiens, GI209862883, Length=272, Percent_Identity=29.7794117647059, Blast_Score=126, Evalue=3e-29,
Organism=Homo sapiens, GI13128860, Length=293, Percent_Identity=27.9863481228669, Blast_Score=102, Evalue=5e-22,
Organism=Homo sapiens, GI8923769, Length=308, Percent_Identity=27.9220779220779, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI293336691, Length=257, Percent_Identity=28.7937743190661, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI20070354, Length=254, Percent_Identity=32.2834645669291, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI13128864, Length=272, Percent_Identity=31.25, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI262073092, Length=234, Percent_Identity=29.4871794871795, Blast_Score=82, Evalue=7e-16,
Organism=Homo sapiens, GI13128862, Length=217, Percent_Identity=29.4930875576037, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI30795202, Length=163, Percent_Identity=36.8098159509202, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI30795204, Length=163, Percent_Identity=36.8098159509202, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI17158039, Length=163, Percent_Identity=36.8098159509202, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI169234807, Length=150, Percent_Identity=38.6666666666667, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI148539870, Length=150, Percent_Identity=38.6666666666667, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI153085395, Length=146, Percent_Identity=36.986301369863, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI62750347, Length=187, Percent_Identity=33.1550802139037, Blast_Score=79, Evalue=6e-15,
Organism=Homo sapiens, GI62750349, Length=187, Percent_Identity=33.1550802139037, Blast_Score=79, Evalue=7e-15,
Organism=Homo sapiens, GI262073088, Length=184, Percent_Identity=29.3478260869565, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI226529806, Length=141, Percent_Identity=33.3333333333333, Blast_Score=72, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI193207430, Length=308, Percent_Identity=28.8961038961039, Blast_Score=128, Evalue=3e-30,
Organism=Caenorhabditis elegans, GI17508561, Length=293, Percent_Identity=27.9863481228669, Blast_Score=98, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI17534739, Length=256, Percent_Identity=28.125, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17561978, Length=295, Percent_Identity=26.7796610169492, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI193206283, Length=182, Percent_Identity=32.4175824175824, Blast_Score=89, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17540332, Length=182, Percent_Identity=32.4175824175824, Blast_Score=88, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17540334, Length=182, Percent_Identity=32.4175824175824, Blast_Score=88, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI17537347, Length=210, Percent_Identity=31.9047619047619, Blast_Score=87, Evalue=9e-18,
Organism=Caenorhabditis elegans, GI193209491, Length=162, Percent_Identity=34.5679012345679, Blast_Score=77, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI25154020, Length=211, Percent_Identity=26.5402843601896, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI25154022, Length=211, Percent_Identity=26.5402843601896, Blast_Score=69, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6321244, Length=307, Percent_Identity=29.6416938110749, Blast_Score=99, Evalue=6e-22,
Organism=Saccharomyces cerevisiae, GI6323999, Length=209, Percent_Identity=31.1004784688995, Blast_Score=94, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6325325, Length=208, Percent_Identity=33.1730769230769, Blast_Score=92, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6324307, Length=173, Percent_Identity=30.635838150289, Blast_Score=77, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24649807, Length=309, Percent_Identity=31.3915857605178, Blast_Score=136, Evalue=2e-32,
Organism=Drosophila melanogaster, GI24657891, Length=293, Percent_Identity=27.9863481228669, Blast_Score=101, Evalue=5e-22,
Organism=Drosophila melanogaster, GI24644244, Length=218, Percent_Identity=29.8165137614679, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24642144, Length=188, Percent_Identity=32.4468085106383, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24642146, Length=188, Percent_Identity=32.4468085106383, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI281360899, Length=188, Percent_Identity=32.4468085106383, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI24642142, Length=188, Percent_Identity=32.4468085106383, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI24641720, Length=158, Percent_Identity=30.379746835443, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI281360799, Length=158, Percent_Identity=30.379746835443, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI281360801, Length=158, Percent_Identity=30.379746835443, Blast_Score=66, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000286 [H]

Pfam domain/function: PF00850 Hist_deacetyl [H]

EC number: NA

Molecular weight: Translated: 33718; Mature: 33718

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELPIIYHPDYVAPLPEGHRFPMAKFKKLYELLLSDDVAQTEQFYTPTLPPLELIELVHT
CCCCEEECCCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHCCCCCCHHHHHHHHCC
PDYVRSYCEGTLDTKAQRRIGLPWSPALANRTCIAVGGTILTAQLALSQGLACNTAGGTH
HHHHHHHHCCCCCCHHHHHCCCCCCCHHCCCEEEEECCHHHHHHHHHHCCCEECCCCCCC
HAFPSYGSGFCIFNDLAIASRVLQQQQIVQKILIVDLDVHQGDGTAFIFQDDDSVFTFSM
CCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCEEEEEECCCCEEEEEE
HCEINFPGTKQHSDLDVPLPVGMEDDAYLQTLASYLPDLLSEIKPDLVLYDAGVDPHIGD
EEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHH
RLGKLALTDTGLFRREMQVLTTCVSAGYPVACVIGGGYADDMTSLVWRHSLVHRAASQVY
HHCCEEECCCHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHH
RQYKL
HHHCC
>Mature Secondary Structure
MELPIIYHPDYVAPLPEGHRFPMAKFKKLYELLLSDDVAQTEQFYTPTLPPLELIELVHT
CCCCEEECCCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHCCCCCCHHHHHHHHCC
PDYVRSYCEGTLDTKAQRRIGLPWSPALANRTCIAVGGTILTAQLALSQGLACNTAGGTH
HHHHHHHHCCCCCCHHHHHCCCCCCCHHCCCEEEEECCHHHHHHHHHHCCCEECCCCCCC
HAFPSYGSGFCIFNDLAIASRVLQQQQIVQKILIVDLDVHQGDGTAFIFQDDDSVFTFSM
CCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCEEEEEECCCCEEEEEE
HCEINFPGTKQHSDLDVPLPVGMEDDAYLQTLASYLPDLLSEIKPDLVLYDAGVDPHIGD
EEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHH
RLGKLALTDTGLFRREMQVLTTCVSAGYPVACVIGGGYADDMTSLVWRHSLVHRAASQVY
HHCCEEECCCHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHH
RQYKL
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7678591 [H]