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The map label for this gene is degU [H]

Identifier: 17230648

GI number: 17230648

Start: 3820512

End: 3821198

Strand: Direct

Name: degU [H]

Synonym: alr3156

Alternate gene names: 17230648

Gene position: 3820512-3821198 (Clockwise)

Preceding gene: 17230647

Following gene: 17230649

Centisome position: 59.57

GC content: 40.76

Gene sequence:

>687_bases
ATGGCTTCTAACCCGGTAAAAATTCTGTTGGTTGAAGATGATGAACTCTTTCGCTTAGGCTTGCGGGTGCGATTACAACA
AGAAGCAGGCTTAGAAATTATTGCTGAGGCTGAAGATGGTGAAACAGCCCTTGATTTAATCAAGCAAAACTCTCTGGATG
TGGTGTTATTAGATGTAGGATTACCAGGGTTGGGGGGAATAGAAGCTTGTAAACAAATTAAGCAGCAAAATCCTCAACTA
CCAATTTTAGTTTTGACTTCCCATTCCCAAAAACCGTTAATTTCTAAATTAATTGAAGCAGGCGCTCAAGGATATTGTCT
CAAAGGAATTATCGCCGAAAAATTAGTATTGGCACTGCGTTCTGTCGCGGCTGGGGCTTCTTGGTGGGATGAAACTGCAA
CGAGGGAAATTCGCTCTTCTATTGAGTCTAGCCAGTCTCAACCGCCAGAACAAAATTTCCCAAAATCTGATCACCCTTTA
ACTGGACGTGAATTAGAAATTTTAGCTTTATTAGCTAAGGGGAAAACGAATCAAGAAATTGCTACGGTACTGTACATTAC
CCCTGGAACAGTTAGAGTTCATGTTCATGCTATTCTACACAAACTAGAGGTTAGCGATCGCCATCAAGCTGTAGTTGTTG
CTTTACAAAAACGGTTGATTCAAAATAGTGCGATCGCAAATGAATAG

Upstream 100 bases:

>100_bases
CATAACGGTATAATTTGGGCAGAGAATAGAGTTCCTACGGGTGCTATGTTTGCATTCAAATTGCCTTTTCTCCCATTTCA
GCCCTCTTTATCTGCGTCAG

Downstream 100 bases:

>100_bases
TTTACCCATTTGGGTAATGCAAAATAAAAAATTTAGATAAATTTTTTATTCCTGACATAAGGGACTTACAGAGTAAAAAA
TATCCAAATGTAGGGTGCGT

Product: two-component response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 228; Mature: 227

Protein sequence:

>228_residues
MASNPVKILLVEDDELFRLGLRVRLQQEAGLEIIAEAEDGETALDLIKQNSLDVVLLDVGLPGLGGIEACKQIKQQNPQL
PILVLTSHSQKPLISKLIEAGAQGYCLKGIIAEKLVLALRSVAAGASWWDETATREIRSSIESSQSQPPEQNFPKSDHPL
TGRELEILALLAKGKTNQEIATVLYITPGTVRVHVHAILHKLEVSDRHQAVVVALQKRLIQNSAIANE

Sequences:

>Translated_228_residues
MASNPVKILLVEDDELFRLGLRVRLQQEAGLEIIAEAEDGETALDLIKQNSLDVVLLDVGLPGLGGIEACKQIKQQNPQL
PILVLTSHSQKPLISKLIEAGAQGYCLKGIIAEKLVLALRSVAAGASWWDETATREIRSSIESSQSQPPEQNFPKSDHPL
TGRELEILALLAKGKTNQEIATVLYITPGTVRVHVHAILHKLEVSDRHQAVVVALQKRLIQNSAIANE
>Mature_227_residues
ASNPVKILLVEDDELFRLGLRVRLQQEAGLEIIAEAEDGETALDLIKQNSLDVVLLDVGLPGLGGIEACKQIKQQNPQLP
ILVLTSHSQKPLISKLIEAGAQGYCLKGIIAEKLVLALRSVAAGASWWDETATREIRSSIESSQSQPPEQNFPKSDHPLT
GRELEILALLAKGKTNQEIATVLYITPGTVRVHVHAILHKLEVSDRHQAVVVALQKRLIQNSAIANE

Specific function: Regulating factor for the production of extracellular proteases. The N-terminal region acts as an inhibitor, whereas the C-terminal region carries enhancing activity [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788222, Length=199, Percent_Identity=34.6733668341709, Blast_Score=129, Evalue=1e-31,
Organism=Escherichia coli, GI1788521, Length=219, Percent_Identity=34.2465753424658, Blast_Score=128, Evalue=3e-31,
Organism=Escherichia coli, GI1786747, Length=198, Percent_Identity=26.7676767676768, Blast_Score=91, Evalue=9e-20,
Organism=Escherichia coli, GI1787473, Length=216, Percent_Identity=30.0925925925926, Blast_Score=87, Evalue=8e-19,
Organism=Escherichia coli, GI1790102, Length=201, Percent_Identity=27.363184079602, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1789937, Length=216, Percent_Identity=24.537037037037, Blast_Score=64, Evalue=9e-12,
Organism=Escherichia coli, GI1788712, Length=173, Percent_Identity=22.5433526011561, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 24857; Mature: 24726

Theoretical pI: Translated: 5.96; Mature: 5.96

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00622 HTH_LUXR_1 ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.4 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASNPVKILLVEDDELFRLGLRVRLQQEAGLEIIAEAEDGETALDLIKQNSLDVVLLDVG
CCCCCEEEEEECCCHHEEHHHHEEEECCCCEEEEEECCCCHHHHHHHHCCCCCEEEEECC
LPGLGGIEACKQIKQQNPQLPILVLTSHSQKPLISKLIEAGAQGYCLKGIIAEKLVLALR
CCCCCHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHCCCCCEEHHHHHHHHHHHHHH
SVAAGASWWDETATREIRSSIESSQSQPPEQNFPKSDHPLTGRELEILALLAKGKTNQEI
HHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCEE
ATVLYITPGTVRVHVHAILHKLEVSDRHQAVVVALQKRLIQNSAIANE
EEEEEECCCEEEEHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
ASNPVKILLVEDDELFRLGLRVRLQQEAGLEIIAEAEDGETALDLIKQNSLDVVLLDVG
CCCCEEEEEECCCHHEEHHHHEEEECCCCEEEEEECCCCHHHHHHHHCCCCCEEEEECC
LPGLGGIEACKQIKQQNPQLPILVLTSHSQKPLISKLIEAGAQGYCLKGIIAEKLVLALR
CCCCCHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHCCCCCEEHHHHHHHHHHHHHH
SVAAGASWWDETATREIRSSIESSQSQPPEQNFPKSDHPLTGRELEILALLAKGKTNQEI
HHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCEE
ATVLYITPGTVRVHVHAILHKLEVSDRHQAVVVALQKRLIQNSAIANE
EEEEEECCCEEEEHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7765823 [H]