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The map label for this gene is luxQ [H]

Identifier: 17230612

GI number: 17230612

Start: 3775927

End: 3779787

Strand: Direct

Name: luxQ [H]

Synonym: alr3120

Alternate gene names: 17230612

Gene position: 3775927-3779787 (Clockwise)

Preceding gene: 17230611

Following gene: 17230613

Centisome position: 58.87

GC content: 46.83

Gene sequence:

>3861_bases
ATGGGAATATTAAAGAATAAATCCCGTTCCTTTTCCATGTTTAATTGCACAACGTCTCTCACCCCATCAGAACTGAAATC
AGCGATCATTCGTGATCCCCTGATAATCAAACCGGAGACAACGGTGATGGATGCGATCGCCCAAATGAGTGGCGTGCGGG
TTATGTGTGACACAGCTAAACTGGATGAAGTCCATCTAGAGGCACGATCAAGCTGCGTGTTGATAGTGGCAGCAGGGAGG
CTATTAGGTATCTTCACTGAGCGAGATGTAGTCAAACTGTGTAGCCAGAGGCGTTGTTTGGAGAATTTGGCGATTCGAGA
GGTGATGATTCATCCAGTCGTCACCCTACGTGAGTCTGAGTTCACCGATTTATTTTTTGCTGTTAATTTGCTCCAACAAT
ACCGCATTCGCCACATTCCGATTCTAGACGAGCAAGAGCGGGTGGTGGGGCTGCTAACCAATGAAAGTCTGCGGCACACT
TCTCGCTCTGTGGATCTCTTGCGGTTGCGTCTGGTGTCTGAGGTGATGACCTGTGAGGTGATTTGTGCTACACCAGATAG
TTCGATGTTGGCGATCGCCCAACAGATGACAGAGAATCGCGTCAGTTCTGTCATGATTGTGCAACTGGGACAGTTTCAAG
ACAAACCCCAGGAAATTCCGGTGGGAATTGTCACCGAGCGGGATATTGTCCAGTTTCAGGCATTAGGCTTGAATCTGGAA
ACCTGTCAGGTTCAGACGGTGATGAGTTCGCCGATTTTTGCCGTGAGACCAGACGATTCTCTGCGGTTCGTGCAGCAGAT
CATGGAGCAGCGTTTGATTCGCCGGTTGGCAGTGACAGGAGATCAGGGGGAGTTATTAGGCATCGTTACCCAAAGTAGTT
TACTACAAGCCCTTAACCCCTTAGAGGTATACAAACTGGCCCAGATGTTGGAAGAAAAGGTGGTGAGGTTAGAGACAGAG
AAGGTTCAACTGCTGGAAAATCGCACTGTTGAACTAGAGCAGCTAGTTGCAGACCGGACAGCTAGTCTCAAGGCTAAGGC
GGGCCGGGAACAAATAGTGTCTGATATCTCCAGACAAATTCGCTCTTCTCTAAGTTTACAAACCATTCTGGACACAACTG
TGGAGCAGGTGCGGCAATTGCTGGGTTGCGATCGCGTCAACATTTGGTATTTTGAAACAGAGTGGGAAAGTATCGTCATG
GCAGAATCTACCACATCTTCCACATCACTGCTGGGCGAACGGATTGAGGAACTCTGCTTTCAGCAACACTCTGCGGAGAT
TTATCGCCAGGGGCGGATTCGTGTCGTCCCAGATATCTACACTATAGAAATGACAGACTGTCACCGGGAGTTCCTGATCC
GCCTCCAGACGCGAGCCAAAATTTTGGTACCCCTGCTGTGTGGCGATGAATTATGGGGTTTGCTCAATGTCAGCGAAAGC
CAACACCCCCGCGAGTGGCAAACTGAAGAAGTTGAACTGCTGCAAGGGTTATCTGTACATCTGGCCATCGCCATTCACCA
AGCTACTACCCACCAAAAATTGCAGGAGCAATTAATCGCCCTTCAGCAAAGGTCAGATCAACTGCGAGGGAGTGAACAGC
GTTATATTACCCTCAGTCAAAACCTAGAAGCCAAAATTGAAGAACGCACGGCTGAACTCCAAGCACGAGAAGCCCAACTC
CAGAAAACATCGGATCGCTTGTCTATATCTCTCAAATCAGGGGCTATCGGCTGTTGGGACTGGGACATTGTAGAGAATAA
CATCTTTTGGGATGAGCGGATGTACGAACTCTATGGTGTCACCAAAACATCTGATTCCCGTTTAGTCTACGACACCTGGG
CAAATAGGCTACATCCCGATGACCGTGCCAATATTGAAGTATTAGTCCAGCAAGCAATTTTAGGACAGGCAGAATACGAT
ACTGAATTTCGTGTTATACATCCTGATGGCAGCATCCACTTCATCAAAGCCTATGGGGTGGTGGTGCGAGATGCTGAGGG
TAATCCTCAGAAAATGATTGGAGTCCACTTTGATATTAGCGATCGCAAAAAATCTGAGGAAATTATTCGCCAACAGGTAG
AAAGGGAGAAACTGCTACGAGAAATCACCCAGAGGATTCGTCAATCTCTAGACCTCCAGACCATTTTTGACATCGCTTGC
CAAGAAATCTGCCAAGTGATTCAGGCTGATCGGGTGGGCATTTTCAAGTTCTATCCCGAATCCAACTTTAATGACGGCGA
ATTTGTAGCTGAATCTGTCGTCAAAGAATTTCCCTCAGTGATAGCAATTCGGGTACACGACCACTGCTTTGGAGAAAACT
ATTCCTCTCTCTATGCTTTGGGTAGGTCTTATGTGGTTGATGATATTTATCACAGTGACATGACAACCTGTCACACTGAT
ATCTTGGCTCAGTTTCATGTGCGTGCCAATGTGATTATGCCGTTACTTTGCGGTGCTGAGTTGTGGGGTTTGCTGTGCAT
CCATCAGTGCGCGACAACTCGCCACTGGCAACAGTCAGAAATTGATTTTACACAACAACTTGCCACCCAGTTAGCGATCG
CCATTCAACAAGCAAGTCTGGTTGAGCAATTACAGCAAGAACTTGCCGAAAGACATCAGGCAGAACTAAAGCTTACCCAA
AGCAATCAACAACTGGCAATTTCTAACCAAGAACTCGCCCGTGCCACTCGTCTCAAAGATGAATTCTTGGCTAACATGAG
CCACGAACTTCGTACACCCCTCAATGCCATTCTCGGCATGACCGAAGGGTTACAAGAAGGAGTTTTTGGCATGATCAATA
ATAAACAATTCAAAGCTTTAGAAACCATTGAGCGTAGCAGCTCTCATTTACTGGATTTGATCAACGATATTCTCGATGTG
GCAAAAATTGAAGCCGGACAGATCAAACTGGATTGCACCACAATTTCAGTAGCTAATCTGTGTGAATCCAGTCTGGTGTT
TATCAAACAGCAGGCATTGCAAAAACGGATTCAGGTGGAAATCAAAATTCCCTTCAATTTACCTGACTTGTTCGTCGATG
AACGCCGGATTCGTCAGGTGTTAATTAACCTGCTCAACAATGCGGTCAAATTCACGCCTGAGGCAGGACGCATTTCCCTA
GAAGTTACTCAACTTTCCCCCGATATATCCACTGTGCAGAACTTCCTGCAAATTGCCGTGATCGATACAGGCATCGGCAT
TATGCAAGAGAATATCAACAAGCTATTTCAGCCCTTCATCCAAATCGATAGCGCTTTAAATCGTCAATATGAGGGTACAG
GGTTGGGACTGGCATTGGTGAAGAAAATTGTCGAACTCCACGGTGGTAGGGTGGGCTTAACTAGTGAACTAGGTATAGGC
AGCTGCTTCACGATTGAACTACCTTGTATTCCCAGTACTCCCGCATCACCGGACTTGATTCGAGATTTATTAACTACCCC
TACTCCAGAACTGGACTCCCCCACTGCTGATGAAGCCGTAAGCCTTGCCCCTGTGATATTGCTAGCAGAAGATAATAAAG
CCAATATCAAAACATTTTCTAGCTACCTCAGCGCCAAAGGCTATGACATTTTGTTGGCAACAAATGGTCAACAAGCCATA
GAACTGGCCACAATTCACCAGCCCGACTTGATTTTGATGGATATCCAAATGCCGGGAATCGACGGTCTAGAGGCAATCCG
ACAGATTCGCCTTGATCCTCAGTTAGTGAATATTCCCATTGTGGCACTCACGGCGCTGGCAATGACTGGCGATCGCGATC
GCTGTTTACAAGCCGGAGCCAATGACTACCTAACTAAACCCGTGAAGCTCAAGCAACTGGCGACCACTATTCAACAGCTT
TTAATTACAACAAAAAAATGA

Upstream 100 bases:

>100_bases
TGTATTTTCTTATCCTAAATATAGGCTGAAACCTTTACTATATAAAAATTAATAAATTGATAATTATCCTGTTGTAGTTC
ATGTAAATTATCTGTTATTG

Downstream 100 bases:

>100_bases
ATCTGCCCTCTATTCTCGTAATTGACGATCTCCCAGATAACTTTGATGTTATTGAAACCCTCTTAAGTGAGCAAGACTAT
ACACTACATTATGTTGCTAG

Product: two-component hybrid sensor and regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 1286; Mature: 1285

Protein sequence:

>1286_residues
MGILKNKSRSFSMFNCTTSLTPSELKSAIIRDPLIIKPETTVMDAIAQMSGVRVMCDTAKLDEVHLEARSSCVLIVAAGR
LLGIFTERDVVKLCSQRRCLENLAIREVMIHPVVTLRESEFTDLFFAVNLLQQYRIRHIPILDEQERVVGLLTNESLRHT
SRSVDLLRLRLVSEVMTCEVICATPDSSMLAIAQQMTENRVSSVMIVQLGQFQDKPQEIPVGIVTERDIVQFQALGLNLE
TCQVQTVMSSPIFAVRPDDSLRFVQQIMEQRLIRRLAVTGDQGELLGIVTQSSLLQALNPLEVYKLAQMLEEKVVRLETE
KVQLLENRTVELEQLVADRTASLKAKAGREQIVSDISRQIRSSLSLQTILDTTVEQVRQLLGCDRVNIWYFETEWESIVM
AESTTSSTSLLGERIEELCFQQHSAEIYRQGRIRVVPDIYTIEMTDCHREFLIRLQTRAKILVPLLCGDELWGLLNVSES
QHPREWQTEEVELLQGLSVHLAIAIHQATTHQKLQEQLIALQQRSDQLRGSEQRYITLSQNLEAKIEERTAELQAREAQL
QKTSDRLSISLKSGAIGCWDWDIVENNIFWDERMYELYGVTKTSDSRLVYDTWANRLHPDDRANIEVLVQQAILGQAEYD
TEFRVIHPDGSIHFIKAYGVVVRDAEGNPQKMIGVHFDISDRKKSEEIIRQQVEREKLLREITQRIRQSLDLQTIFDIAC
QEICQVIQADRVGIFKFYPESNFNDGEFVAESVVKEFPSVIAIRVHDHCFGENYSSLYALGRSYVVDDIYHSDMTTCHTD
ILAQFHVRANVIMPLLCGAELWGLLCIHQCATTRHWQQSEIDFTQQLATQLAIAIQQASLVEQLQQELAERHQAELKLTQ
SNQQLAISNQELARATRLKDEFLANMSHELRTPLNAILGMTEGLQEGVFGMINNKQFKALETIERSSSHLLDLINDILDV
AKIEAGQIKLDCTTISVANLCESSLVFIKQQALQKRIQVEIKIPFNLPDLFVDERRIRQVLINLLNNAVKFTPEAGRISL
EVTQLSPDISTVQNFLQIAVIDTGIGIMQENINKLFQPFIQIDSALNRQYEGTGLGLALVKKIVELHGGRVGLTSELGIG
SCFTIELPCIPSTPASPDLIRDLLTTPTPELDSPTADEAVSLAPVILLAEDNKANIKTFSSYLSAKGYDILLATNGQQAI
ELATIHQPDLILMDIQMPGIDGLEAIRQIRLDPQLVNIPIVALTALAMTGDRDRCLQAGANDYLTKPVKLKQLATTIQQL
LITTKK

Sequences:

>Translated_1286_residues
MGILKNKSRSFSMFNCTTSLTPSELKSAIIRDPLIIKPETTVMDAIAQMSGVRVMCDTAKLDEVHLEARSSCVLIVAAGR
LLGIFTERDVVKLCSQRRCLENLAIREVMIHPVVTLRESEFTDLFFAVNLLQQYRIRHIPILDEQERVVGLLTNESLRHT
SRSVDLLRLRLVSEVMTCEVICATPDSSMLAIAQQMTENRVSSVMIVQLGQFQDKPQEIPVGIVTERDIVQFQALGLNLE
TCQVQTVMSSPIFAVRPDDSLRFVQQIMEQRLIRRLAVTGDQGELLGIVTQSSLLQALNPLEVYKLAQMLEEKVVRLETE
KVQLLENRTVELEQLVADRTASLKAKAGREQIVSDISRQIRSSLSLQTILDTTVEQVRQLLGCDRVNIWYFETEWESIVM
AESTTSSTSLLGERIEELCFQQHSAEIYRQGRIRVVPDIYTIEMTDCHREFLIRLQTRAKILVPLLCGDELWGLLNVSES
QHPREWQTEEVELLQGLSVHLAIAIHQATTHQKLQEQLIALQQRSDQLRGSEQRYITLSQNLEAKIEERTAELQAREAQL
QKTSDRLSISLKSGAIGCWDWDIVENNIFWDERMYELYGVTKTSDSRLVYDTWANRLHPDDRANIEVLVQQAILGQAEYD
TEFRVIHPDGSIHFIKAYGVVVRDAEGNPQKMIGVHFDISDRKKSEEIIRQQVEREKLLREITQRIRQSLDLQTIFDIAC
QEICQVIQADRVGIFKFYPESNFNDGEFVAESVVKEFPSVIAIRVHDHCFGENYSSLYALGRSYVVDDIYHSDMTTCHTD
ILAQFHVRANVIMPLLCGAELWGLLCIHQCATTRHWQQSEIDFTQQLATQLAIAIQQASLVEQLQQELAERHQAELKLTQ
SNQQLAISNQELARATRLKDEFLANMSHELRTPLNAILGMTEGLQEGVFGMINNKQFKALETIERSSSHLLDLINDILDV
AKIEAGQIKLDCTTISVANLCESSLVFIKQQALQKRIQVEIKIPFNLPDLFVDERRIRQVLINLLNNAVKFTPEAGRISL
EVTQLSPDISTVQNFLQIAVIDTGIGIMQENINKLFQPFIQIDSALNRQYEGTGLGLALVKKIVELHGGRVGLTSELGIG
SCFTIELPCIPSTPASPDLIRDLLTTPTPELDSPTADEAVSLAPVILLAEDNKANIKTFSSYLSAKGYDILLATNGQQAI
ELATIHQPDLILMDIQMPGIDGLEAIRQIRLDPQLVNIPIVALTALAMTGDRDRCLQAGANDYLTKPVKLKQLATTIQQL
LITTKK
>Mature_1285_residues
GILKNKSRSFSMFNCTTSLTPSELKSAIIRDPLIIKPETTVMDAIAQMSGVRVMCDTAKLDEVHLEARSSCVLIVAAGRL
LGIFTERDVVKLCSQRRCLENLAIREVMIHPVVTLRESEFTDLFFAVNLLQQYRIRHIPILDEQERVVGLLTNESLRHTS
RSVDLLRLRLVSEVMTCEVICATPDSSMLAIAQQMTENRVSSVMIVQLGQFQDKPQEIPVGIVTERDIVQFQALGLNLET
CQVQTVMSSPIFAVRPDDSLRFVQQIMEQRLIRRLAVTGDQGELLGIVTQSSLLQALNPLEVYKLAQMLEEKVVRLETEK
VQLLENRTVELEQLVADRTASLKAKAGREQIVSDISRQIRSSLSLQTILDTTVEQVRQLLGCDRVNIWYFETEWESIVMA
ESTTSSTSLLGERIEELCFQQHSAEIYRQGRIRVVPDIYTIEMTDCHREFLIRLQTRAKILVPLLCGDELWGLLNVSESQ
HPREWQTEEVELLQGLSVHLAIAIHQATTHQKLQEQLIALQQRSDQLRGSEQRYITLSQNLEAKIEERTAELQAREAQLQ
KTSDRLSISLKSGAIGCWDWDIVENNIFWDERMYELYGVTKTSDSRLVYDTWANRLHPDDRANIEVLVQQAILGQAEYDT
EFRVIHPDGSIHFIKAYGVVVRDAEGNPQKMIGVHFDISDRKKSEEIIRQQVEREKLLREITQRIRQSLDLQTIFDIACQ
EICQVIQADRVGIFKFYPESNFNDGEFVAESVVKEFPSVIAIRVHDHCFGENYSSLYALGRSYVVDDIYHSDMTTCHTDI
LAQFHVRANVIMPLLCGAELWGLLCIHQCATTRHWQQSEIDFTQQLATQLAIAIQQASLVEQLQQELAERHQAELKLTQS
NQQLAISNQELARATRLKDEFLANMSHELRTPLNAILGMTEGLQEGVFGMINNKQFKALETIERSSSHLLDLINDILDVA
KIEAGQIKLDCTTISVANLCESSLVFIKQQALQKRIQVEIKIPFNLPDLFVDERRIRQVLINLLNNAVKFTPEAGRISLE
VTQLSPDISTVQNFLQIAVIDTGIGIMQENINKLFQPFIQIDSALNRQYEGTGLGLALVKKIVELHGGRVGLTSELGIGS
CFTIELPCIPSTPASPDLIRDLLTTPTPELDSPTADEAVSLAPVILLAEDNKANIKTFSSYLSAKGYDILLATNGQQAIE
LATIHQPDLILMDIQMPGIDGLEAIRQIRLDPQLVNIPIVALTALAMTGDRDRCLQAGANDYLTKPVKLKQLATTIQQLL
ITTKK

Specific function: At low cell density, in absence of AI-2 (autoinducer 2), luxQ has a kinase activity and autophosphorylates on a histidine residue. The phosphoryl group is then transferred to an aspartate residue in the response regulator domain. The phosphoryl group is t

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI48994928, Length=395, Percent_Identity=33.1645569620253, Blast_Score=184, Evalue=4e-47,
Organism=Escherichia coli, GI1788713, Length=400, Percent_Identity=32.25, Blast_Score=179, Evalue=7e-46,
Organism=Escherichia coli, GI1789149, Length=293, Percent_Identity=34.1296928327645, Blast_Score=157, Evalue=3e-39,
Organism=Escherichia coli, GI87081816, Length=344, Percent_Identity=33.4302325581395, Blast_Score=147, Evalue=4e-36,
Organism=Escherichia coli, GI145693157, Length=266, Percent_Identity=36.0902255639098, Blast_Score=139, Evalue=9e-34,
Organism=Escherichia coli, GI1788393, Length=258, Percent_Identity=27.906976744186, Blast_Score=104, Evalue=4e-23,
Organism=Escherichia coli, GI1786600, Length=236, Percent_Identity=31.3559322033898, Blast_Score=102, Evalue=1e-22,
Organism=Escherichia coli, GI1790436, Length=226, Percent_Identity=29.2035398230088, Blast_Score=101, Evalue=3e-22,
Organism=Escherichia coli, GI1786912, Length=256, Percent_Identity=28.515625, Blast_Score=93, Evalue=1e-19,
Organism=Escherichia coli, GI1786783, Length=235, Percent_Identity=28.936170212766, Blast_Score=92, Evalue=2e-19,
Organism=Escherichia coli, GI87082128, Length=237, Percent_Identity=29.535864978903, Blast_Score=90, Evalue=1e-18,
Organism=Escherichia coli, GI1788549, Length=246, Percent_Identity=28.0487804878049, Blast_Score=89, Evalue=2e-18,
Organism=Escherichia coli, GI1788381, Length=152, Percent_Identity=28.9473684210526, Blast_Score=82, Evalue=2e-16,
Organism=Escherichia coli, GI1787894, Length=237, Percent_Identity=29.1139240506329, Blast_Score=81, Evalue=4e-16,
Organism=Escherichia coli, GI1788279, Length=238, Percent_Identity=28.1512605042017, Blast_Score=78, Evalue=4e-15,
Organism=Escherichia coli, GI1790346, Length=239, Percent_Identity=28.0334728033473, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI1788394, Length=118, Percent_Identity=35.5932203389831, Blast_Score=73, Evalue=1e-13,
Organism=Escherichia coli, GI1790863, Length=122, Percent_Identity=32.7868852459016, Blast_Score=72, Evalue=2e-13,
Organism=Escherichia coli, GI87082012, Length=113, Percent_Identity=36.283185840708, Blast_Score=72, Evalue=2e-13,
Organism=Escherichia coli, GI1790861, Length=221, Percent_Identity=29.4117647058824, Blast_Score=71, Evalue=5e-13,
Organism=Escherichia coli, GI1788550, Length=117, Percent_Identity=34.1880341880342, Blast_Score=71, Evalue=5e-13,
Organism=Escherichia coli, GI1786784, Length=116, Percent_Identity=33.6206896551724, Blast_Score=69, Evalue=2e-12,
Organism=Escherichia coli, GI1786911, Length=108, Percent_Identity=33.3333333333333, Blast_Score=69, Evalue=3e-12,
Organism=Escherichia coli, GI1786599, Length=120, Percent_Identity=32.5, Blast_Score=67, Evalue=7e-12,
Organism=Escherichia coli, GI1790437, Length=120, Percent_Identity=31.6666666666667, Blast_Score=65, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6322044, Length=121, Percent_Identity=38.0165289256198, Blast_Score=74, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6323034, Length=171, Percent_Identity=31.5789473684211, Blast_Score=66, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR015387
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789
- ProDom:   PD142495 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF09308 LuxQ-periplasm; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 145127; Mature: 144996

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: PS50113 PAC ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN ; PS50046 PHYTOCHROME_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGILKNKSRSFSMFNCTTSLTPSELKSAIIRDPLIIKPETTVMDAIAQMSGVRVMCDTAK
CCCCCCCCCCEEEEEEECCCCHHHHHHHHHCCCEEECCCHHHHHHHHHHCCCEEEECCCC
LDEVHLEARSSCVLIVAAGRLLGIFTERDVVKLCSQRRCLENLAIREVMIHPVVTLRESE
HHHHHHHCCCCEEEEEECCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCC
FTDLFFAVNLLQQYRIRHIPILDEQERVVGLLTNESLRHTSRSVDLLRLRLVSEVMTCEV
HHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHEEEE
ICATPDSSMLAIAQQMTENRVSSVMIVQLGQFQDKPQEIPVGIVTERDIVQFQALGLNLE
EEECCCCHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCCEEEEECCHHHHHHHHCCCCH
TCQVQTVMSSPIFAVRPDDSLRFVQQIMEQRLIRRLAVTGDQGELLGIVTQSSLLQALNP
HHEEHHHHCCCEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEHHHHHHHCCH
LEVYKLAQMLEEKVVRLETEKVQLLENRTVELEQLVADRTASLKAKAGREQIVSDISRQI
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
RSSLSLQTILDTTVEQVRQLLGCDRVNIWYFETEWESIVMAESTTSSTSLLGERIEELCF
HHHCHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCEEEEECCCCCHHHHHHHHHHHHHH
QQHSAEIYRQGRIRVVPDIYTIEMTDCHREFLIRLQTRAKILVPLLCGDELWGLLNVSES
HHHHHHHHHCCCEEEECCEEEEEEHHHHHHHHHHHHCCCEEEEEEEECCHHHHEEECCCC
QHPREWQTEEVELLQGLSVHLAIAIHQATTHQKLQEQLIALQQRSDQLRGSEQRYITLSQ
CCCCCCCHHHHHHHCCCCEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECC
NLEAKIEERTAELQAREAQLQKTSDRLSISLKSGAIGCWDWDIVENNIFWDERMYELYGV
CCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCEEEEEEHHEECCCCCHHHHHHHHHCC
TKTSDSRLVYDTWANRLHPDDRANIEVLVQQAILGQAEYDTEFRVIHPDGSIHFIKAYGV
EECCCCEEEEEHHHHCCCCCCCCCHHHHHHHHHHCCCCCCCEEEEECCCCCEEEEEEEEE
VVRDAEGNPQKMIGVHFDISDRKKSEEIIRQQVEREKLLREITQRIRQSLDLQTIFDIAC
EEECCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
QEICQVIQADRVGIFKFYPESNFNDGEFVAESVVKEFPSVIAIRVHDHCFGENYSSLYAL
HHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHHCCCEEEEEEECCCCCCCHHHHHHH
GRSYVVDDIYHSDMTTCHTDILAQFHVRANVIMPLLCGAELWGLLCIHQCATTRHWQQSE
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
IDFTQQLATQLAIAIQQASLVEQLQQELAERHQAELKLTQSNQQLAISNQELARATRLKD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCEEEECHHHHHHHHHHHH
EFLANMSHELRTPLNAILGMTEGLQEGVFGMINNKQFKALETIERSSSHLLDLINDILDV
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
AKIEAGQIKLDCTTISVANLCESSLVFIKQQALQKRIQVEIKIPFNLPDLFVDERRIRQV
HHCCCCEEEEEEEEEHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCHHHHHHHHHHHH
LINLLNNAVKFTPEAGRISLEVTQLSPDISTVQNFLQIAVIDTGIGIMQENINKLFQPFI
HHHHHHHHEEECCCCCEEEEEEEECCCCHHHHHHHHHHHHEECCHHHHHHHHHHHHHHHH
QIDSALNRQYEGTGLGLALVKKIVELHGGRVGLTSELGIGSCFTIELPCIPSTPASPDLI
HHHHHHCCCCCCCCCHHHHHHHHHHHCCCCEEEECCCCCCEEEEEEECCCCCCCCCHHHH
RDLLTTPTPELDSPTADEAVSLAPVILLAEDNKANIKTFSSYLSAKGYDILLATNGQQAI
HHHHCCCCCCCCCCCCHHHHHHCEEEEEECCCCCHHHHHHHHHCCCCCEEEEEECCCCEE
ELATIHQPDLILMDIQMPGIDGLEAIRQIRLDPQLVNIPIVALTALAMTGDRDRCLQAGA
EEEEECCCCEEEEEEECCCCCHHHHHHHHCCCCEEECCHHHHHHHHHHCCCHHHHHHCCC
NDYLTKPVKLKQLATTIQQLLITTKK
CHHCCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
GILKNKSRSFSMFNCTTSLTPSELKSAIIRDPLIIKPETTVMDAIAQMSGVRVMCDTAK
CCCCCCCCCEEEEEEECCCCHHHHHHHHHCCCEEECCCHHHHHHHHHHCCCEEEECCCC
LDEVHLEARSSCVLIVAAGRLLGIFTERDVVKLCSQRRCLENLAIREVMIHPVVTLRESE
HHHHHHHCCCCEEEEEECCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCC
FTDLFFAVNLLQQYRIRHIPILDEQERVVGLLTNESLRHTSRSVDLLRLRLVSEVMTCEV
HHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHEEEE
ICATPDSSMLAIAQQMTENRVSSVMIVQLGQFQDKPQEIPVGIVTERDIVQFQALGLNLE
EEECCCCHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCCEEEEECCHHHHHHHHCCCCH
TCQVQTVMSSPIFAVRPDDSLRFVQQIMEQRLIRRLAVTGDQGELLGIVTQSSLLQALNP
HHEEHHHHCCCEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEHHHHHHHCCH
LEVYKLAQMLEEKVVRLETEKVQLLENRTVELEQLVADRTASLKAKAGREQIVSDISRQI
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
RSSLSLQTILDTTVEQVRQLLGCDRVNIWYFETEWESIVMAESTTSSTSLLGERIEELCF
HHHCHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCEEEEECCCCCHHHHHHHHHHHHHH
QQHSAEIYRQGRIRVVPDIYTIEMTDCHREFLIRLQTRAKILVPLLCGDELWGLLNVSES
HHHHHHHHHCCCEEEECCEEEEEEHHHHHHHHHHHHCCCEEEEEEEECCHHHHEEECCCC
QHPREWQTEEVELLQGLSVHLAIAIHQATTHQKLQEQLIALQQRSDQLRGSEQRYITLSQ
CCCCCCCHHHHHHHCCCCEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECC
NLEAKIEERTAELQAREAQLQKTSDRLSISLKSGAIGCWDWDIVENNIFWDERMYELYGV
CCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCEEEEEEHHEECCCCCHHHHHHHHHCC
TKTSDSRLVYDTWANRLHPDDRANIEVLVQQAILGQAEYDTEFRVIHPDGSIHFIKAYGV
EECCCCEEEEEHHHHCCCCCCCCCHHHHHHHHHHCCCCCCCEEEEECCCCCEEEEEEEEE
VVRDAEGNPQKMIGVHFDISDRKKSEEIIRQQVEREKLLREITQRIRQSLDLQTIFDIAC
EEECCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
QEICQVIQADRVGIFKFYPESNFNDGEFVAESVVKEFPSVIAIRVHDHCFGENYSSLYAL
HHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHHCCCEEEEEEECCCCCCCHHHHHHH
GRSYVVDDIYHSDMTTCHTDILAQFHVRANVIMPLLCGAELWGLLCIHQCATTRHWQQSE
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
IDFTQQLATQLAIAIQQASLVEQLQQELAERHQAELKLTQSNQQLAISNQELARATRLKD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCEEEECHHHHHHHHHHHH
EFLANMSHELRTPLNAILGMTEGLQEGVFGMINNKQFKALETIERSSSHLLDLINDILDV
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
AKIEAGQIKLDCTTISVANLCESSLVFIKQQALQKRIQVEIKIPFNLPDLFVDERRIRQV
HHCCCCEEEEEEEEEHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCHHHHHHHHHHHH
LINLLNNAVKFTPEAGRISLEVTQLSPDISTVQNFLQIAVIDTGIGIMQENINKLFQPFI
HHHHHHHHEEECCCCCEEEEEEEECCCCHHHHHHHHHHHHEECCHHHHHHHHHHHHHHHH
QIDSALNRQYEGTGLGLALVKKIVELHGGRVGLTSELGIGSCFTIELPCIPSTPASPDLI
HHHHHHCCCCCCCCCHHHHHHHHHHHCCCCEEEECCCCCCEEEEEEECCCCCCCCCHHHH
RDLLTTPTPELDSPTADEAVSLAPVILLAEDNKANIKTFSSYLSAKGYDILLATNGQQAI
HHHHCCCCCCCCCCCCHHHHHHCEEEEEECCCCCHHHHHHHHHCCCCCEEEEEECCCCEE
ELATIHQPDLILMDIQMPGIDGLEAIRQIRLDPQLVNIPIVALTALAMTGDRDRCLQAGA
EEEEECCCCEEEEEEECCCCCHHHHHHHHCCCCEEECCHHHHHHHHHHCCCHHHHHHCCC
NDYLTKPVKLKQLATTIQQLLITTKK
CHHCCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10952301; 12176318 [H]