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The map label for this gene is kaiC

Identifier: 17230378

GI number: 17230378

Start: 3523433

End: 3524992

Strand: Direct

Name: kaiC

Synonym: alr2886

Alternate gene names: 17230378

Gene position: 3523433-3524992 (Clockwise)

Preceding gene: 17230377

Following gene: 17230379

Centisome position: 54.94

GC content: 42.12

Gene sequence:

>1560_bases
ATGAGTGAGAAAGAGCAGCAGGAACAACAAAATACATCTGGTAATGGTGTAGAAAAAATTCGCACGATGATTGAAGGCTT
TGACGATATTAGTCATGGCGGCTTGCCCGTTGGTAGAACTACTTTAGTCAGTGGAACCTCTGGAACAGGCAAAACTTTAT
TATCTCTACAGTTTCTCTTTAACGGCATCAGCTTCTTTGATGAACCAGGTGTATTTGTCACCTTTGAAGAATCGCCCAGC
GACATCATCAAAAATGCTCATATTTTTGGCTGGAACTTACAACGCCTAATTAATGAGGGTAAATTATTTATTCTGGACGC
ATCCCCCGACCCAGAAGGTCAAGATATCGTTGGTAACTTTGACCTTTCTGCATTAATTGAGCGCTTGCAATATGCCATTC
GCAAATACAAAGCCAAAAGAGTATCCATCGACTCCATCACCGCCGTATTCCAGCAGTATGAAGCAGTGGGAGTGGTGCGT
CGAGAGATTTTTCGCCTAGTAGCGCGTCTCAAACAACTGAATGTCACTACAATAATTACCACCGAACGCAGCGAAGAATA
TGGGCCAGTAGCCTCCTTTGGTGTAGAGGAATTTGTATCCGATAACGTGGTCATAGCCCGTAACGTTTTAGAAGGAGAAC
GTCGCCGCCGCACCATTGAAATACTGAAATTGCGCGGTACAACTCACATGAAAGGTGAGTATCCTTTCACAATTACCAAT
GATGGTGTGAACATTTTCCCATTAGGAGCAATGCGCTTGACTCAAAGGTCTTCTAATGTCCGGGTTTCTTCTGGTGTTAA
AACTCTAGATGGAATGTGCGGTGGTGGGTTCTTTAAAGACTCAATTATTTTAGCCACAGGCGCTACAGGTACAGGTAAAA
CCCTGTTAGTGAGCAAATTTTTACAAAATGGCTGCGTCAACAACGAGCGAGCGATATTATTCGCTTATGAAGAATCACGC
GCTCAACTATCTCGGAATGCTTATTCTTGGGGTATTGATTTTGAAGAATTAGAAAGCCAAGGTTTACTGAAAATTATTTG
TACCTACCCAGAATCAACTGGCTTAGAAGACCACCTGCAAATTATTAAGTCCGAAATTGCCTATTTTAAACCAGCGAGAA
TTGCTATTGATTCACTGTCAGCACTTGCTAGAGGTGTAAGTAATAATGCTTTCCGGCAGTTTGTTATTGGTGTCACAGGT
TATGCCAAACAAGAAGAAATTACTGGCTTCTTTACTAACACAACTGACCAATTTATGGGGTCTCATTCCATAACTGACTC
TCACATCTCTACAATTACCGACACAATCTTAATGCTACAGTACGTAGAGATTCGTGGGGAAATGTCAAGAGCAATTAACG
TATTTAAGATGAGAGGTTCCTGGCACGACAAAGGAATCAGAGAATATAATATCACGGCAGATGGCCCAGAAATTCAAGAT
TCTTTCCGTAACTACGAAAGAATTGTCAGTGGCTCTCCTACCCGCGTTAGTATTGACGAGAAAGCGGAACTTTCTCGGAT
AGTCAGACGTTTTGAAGACAAACAGGGTTCCGATTCCTAA

Upstream 100 bases:

>100_bases
ATTGGGAAGCACAAAGTAATCTTTAATCTTTGGTGTTAAAAATAATTTACCAACTTTAGTCATATAAAAACTGGGGATAG
CACCCCATTATTAGCAAACG

Downstream 100 bases:

>100_bases
ATTTGGTATCGTACTATATTCCTCTTTAAATTTAGTATCGTGCTATATTCTGTGGTGAAGAAAAGTTTTCTGCCGCCAGA
TTAATTTTCGTGTGAGGGGA

Product: circadian clock protein KaiC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 519; Mature: 518

Protein sequence:

>519_residues
MSEKEQQEQQNTSGNGVEKIRTMIEGFDDISHGGLPVGRTTLVSGTSGTGKTLLSLQFLFNGISFFDEPGVFVTFEESPS
DIIKNAHIFGWNLQRLINEGKLFILDASPDPEGQDIVGNFDLSALIERLQYAIRKYKAKRVSIDSITAVFQQYEAVGVVR
REIFRLVARLKQLNVTTIITTERSEEYGPVASFGVEEFVSDNVVIARNVLEGERRRRTIEILKLRGTTHMKGEYPFTITN
DGVNIFPLGAMRLTQRSSNVRVSSGVKTLDGMCGGGFFKDSIILATGATGTGKTLLVSKFLQNGCVNNERAILFAYEESR
AQLSRNAYSWGIDFEELESQGLLKIICTYPESTGLEDHLQIIKSEIAYFKPARIAIDSLSALARGVSNNAFRQFVIGVTG
YAKQEEITGFFTNTTDQFMGSHSITDSHISTITDTILMLQYVEIRGEMSRAINVFKMRGSWHDKGIREYNITADGPEIQD
SFRNYERIVSGSPTRVSIDEKAELSRIVRRFEDKQGSDS

Sequences:

>Translated_519_residues
MSEKEQQEQQNTSGNGVEKIRTMIEGFDDISHGGLPVGRTTLVSGTSGTGKTLLSLQFLFNGISFFDEPGVFVTFEESPS
DIIKNAHIFGWNLQRLINEGKLFILDASPDPEGQDIVGNFDLSALIERLQYAIRKYKAKRVSIDSITAVFQQYEAVGVVR
REIFRLVARLKQLNVTTIITTERSEEYGPVASFGVEEFVSDNVVIARNVLEGERRRRTIEILKLRGTTHMKGEYPFTITN
DGVNIFPLGAMRLTQRSSNVRVSSGVKTLDGMCGGGFFKDSIILATGATGTGKTLLVSKFLQNGCVNNERAILFAYEESR
AQLSRNAYSWGIDFEELESQGLLKIICTYPESTGLEDHLQIIKSEIAYFKPARIAIDSLSALARGVSNNAFRQFVIGVTG
YAKQEEITGFFTNTTDQFMGSHSITDSHISTITDTILMLQYVEIRGEMSRAINVFKMRGSWHDKGIREYNITADGPEIQD
SFRNYERIVSGSPTRVSIDEKAELSRIVRRFEDKQGSDS
>Mature_518_residues
SEKEQQEQQNTSGNGVEKIRTMIEGFDDISHGGLPVGRTTLVSGTSGTGKTLLSLQFLFNGISFFDEPGVFVTFEESPSD
IIKNAHIFGWNLQRLINEGKLFILDASPDPEGQDIVGNFDLSALIERLQYAIRKYKAKRVSIDSITAVFQQYEAVGVVRR
EIFRLVARLKQLNVTTIITTERSEEYGPVASFGVEEFVSDNVVIARNVLEGERRRRTIEILKLRGTTHMKGEYPFTITND
GVNIFPLGAMRLTQRSSNVRVSSGVKTLDGMCGGGFFKDSIILATGATGTGKTLLVSKFLQNGCVNNERAILFAYEESRA
QLSRNAYSWGIDFEELESQGLLKIICTYPESTGLEDHLQIIKSEIAYFKPARIAIDSLSALARGVSNNAFRQFVIGVTGY
AKQEEITGFFTNTTDQFMGSHSITDSHISTITDTILMLQYVEIRGEMSRAINVFKMRGSWHDKGIREYNITADGPEIQDS
FRNYERIVSGSPTRVSIDEKAELSRIVRRFEDKQGSDS

Specific function: Core component of the kaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The kaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by actin

COG id: COG0467

COG function: function code T; RecA-superfamily ATPases implicated in signal transduction

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 2 kaiC domains

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): KAIC_NOSS1 (Q8YT40)

Other databases:

- EMBL:   AB071284
- EMBL:   BA000019
- PIR:   AG2166
- RefSeq:   NP_486926.1
- ProteinModelPortal:   Q8YT40
- SMR:   Q8YT40
- STRING:   Q8YT40
- GeneID:   1106484
- GenomeReviews:   BA000019_GR
- KEGG:   ana:alr2886
- NMPDR:   fig|103690.1.peg.3193
- eggNOG:   COG0467
- HOGENOM:   HBG519240
- OMA:   AFRQFVI
- ProtClustDB:   PRK09302
- BioCyc:   NSP103690:ALR2886-MONOMER
- GO:   GO:0006350
- HAMAP:   MF_01836
- InterPro:   IPR014774
- InterPro:   IPR013503
- InterPro:   IPR010624
- TIGRFAMs:   TIGR02655

Pfam domain/function: PF06745 KaiC

EC number: =2.7.11.1

Molecular weight: Translated: 57920; Mature: 57789

Theoretical pI: Translated: 5.79; Mature: 5.79

Prosite motif: PS51146 KAIC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEKEQQEQQNTSGNGVEKIRTMIEGFDDISHGGLPVGRTTLVSGTSGTGKTLLSLQFLF
CCCHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHH
NGISFFDEPGVFVTFEESPSDIIKNAHIFGWNLQRLINEGKLFILDASPDPEGQDIVGNF
CCHHHCCCCCEEEEECCCCHHHHCCCEEECCCHHHHHCCCCEEEEECCCCCCCCCEEECC
DLSALIERLQYAIRKYKAKRVSIDSITAVFQQYEAVGVVRREIFRLVARLKQLNVTTIIT
CHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEE
TERSEEYGPVASFGVEEFVSDNVVIARNVLEGERRRRTIEILKLRGTTHMKGEYPFTITN
ECCCCCCCCHHHHCHHHHHCCCEEEEHHHHHHHHHHCEEEEEEECCCCCCCCCCCEEEEC
DGVNIFPLGAMRLTQRSSNVRVSSGVKTLDGMCGGGFFKDSIILATGATGTGKTLLVSKF
CCCEEEEECHHHHHHCCCCEEECCCCHHHCCCCCCCEECCCEEEEECCCCCCHHHHHHHH
LQNGCVNNERAILFAYEESRAQLSRNAYSWGIDFEELESQGLLKIICTYPESTGLEDHLQ
HHCCCCCCCCEEEEEECHHHHHHHCCCEECCCCHHHHCCCCEEEEEEECCCCCCHHHHHH
IIKSEIAYFKPARIAIDSLSALARGVSNNAFRQFVIGVTGYAKQEEITGFFTNTTDQFMG
HHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHEECCCCCCCHHCCEEECCCHHHHCC
SHSITDSHISTITDTILMLQYVEIRGEMSRAINVFKMRGSWHDKGIREYNITADGPEIQD
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEHEEECCCCCCCCCEEEECCCCCCHHHH
SFRNYERIVSGSPTRVSIDEKAELSRIVRRFEDKQGSDS
HHHHHHHHHCCCCCEEECCHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SEKEQQEQQNTSGNGVEKIRTMIEGFDDISHGGLPVGRTTLVSGTSGTGKTLLSLQFLF
CCHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHH
NGISFFDEPGVFVTFEESPSDIIKNAHIFGWNLQRLINEGKLFILDASPDPEGQDIVGNF
CCHHHCCCCCEEEEECCCCHHHHCCCEEECCCHHHHHCCCCEEEEECCCCCCCCCEEECC
DLSALIERLQYAIRKYKAKRVSIDSITAVFQQYEAVGVVRREIFRLVARLKQLNVTTIIT
CHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEE
TERSEEYGPVASFGVEEFVSDNVVIARNVLEGERRRRTIEILKLRGTTHMKGEYPFTITN
ECCCCCCCCHHHHCHHHHHCCCEEEEHHHHHHHHHHCEEEEEEECCCCCCCCCCCEEEEC
DGVNIFPLGAMRLTQRSSNVRVSSGVKTLDGMCGGGFFKDSIILATGATGTGKTLLVSKF
CCCEEEEECHHHHHHCCCCEEECCCCHHHCCCCCCCEECCCEEEEECCCCCCHHHHHHHH
LQNGCVNNERAILFAYEESRAQLSRNAYSWGIDFEELESQGLLKIICTYPESTGLEDHLQ
HHCCCCCCCCEEEEEECHHHHHHHCCCEECCCCHHHHCCCCEEEEEEECCCCCCHHHHHH
IIKSEIAYFKPARIAIDSLSALARGVSNNAFRQFVIGVTGYAKQEEITGFFTNTTDQFMG
HHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHEECCCCCCCHHCCEEECCCHHHHCC
SHSITDSHISTITDTILMLQYVEIRGEMSRAINVFKMRGSWHDKGIREYNITADGPEIQD
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEHEEECCCCCCCCCEEEECCCCCCHHHH
SFRNYERIVSGSPTRVSIDEKAELSRIVRRFEDKQGSDS
HHHHHHHHHCCCCCEEECCHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11759840