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The map label for this gene is exoB [H]

Identifier: 17230345

GI number: 17230345

Start: 3474859

End: 3475869

Strand: Reverse

Name: exoB [H]

Synonym: all2853

Alternate gene names: 17230345

Gene position: 3475869-3474859 (Counterclockwise)

Preceding gene: 17230346

Following gene: 17230344

Centisome position: 54.19

GC content: 43.92

Gene sequence:

>1011_bases
ATGAATCAAAAAGTTTTAGTTACCGGTGGTGCTGGCTACATTGGTTCTCATGTGGTGCGCCAGCTAGGTGAAGCCGGCTA
CGATGTTGTTGTGTATGATAACTGCTCTACAGGTTCACCCCAAGCCGTACTACATGGTGAGTTAATTATCGGTGATTTAA
AAAATTCCGAATGCCTTTCTCAAGTATTTCATCAACATAAATTTACGGCAGTTTTACACTTCGCCGCTAGCCTGAGCGTA
CCAGAATCTGTTGCCCGTCCCCTAGACTACTACGCTAACAACACGCGCAACACTTTAAATTTACTTCGTTGTTGTCACGA
CACAGGTGTTAACCAAATAATCTTTTCTAGCACCGCAGCCGTTTATGGACAACCGGAAACTGCCGTTGTCACCGAATCTA
CAGCAACTGAACCGATTAATCCCTATGGACGCTCAAAACTTTCTTGTGAATGGTTGATTCGTGACCACGCCAAAGCTTCT
GATCTACGCTATGTCATTCTACGTTACTTTAATGTTGCCGGAGCCGAACCCGGTGGGCGATTGGGACAGATGACAAAAGA
CGCATCTCATTTAATTCGTGTCACTTGTGATGCTGCACTCAAACGCAGATTAGGAGTAAAAATTTTTGGTACAGATTTCC
CCACACCAGACGGAACGGCAATTAGAGACTACATTCATGTAGAAGACCTCGCAACAGCACATTTAGACGCTTTAGTTTAT
TTAGAGCAAGGTAACAGCAGCCAAATTCTTAACTGTGGTTATGGACAAGGCTATAGTGTCCGTCAAGTTATCGACCGGGT
GAAGGCAATTTCTGGCGTAGATTTTCCGGTGATAGAAGCGGAGCGTCGTTCTGGTGATCCGGTTTGTGTGACAGCTTGTA
CTGATAAAATTCGTCAAGTATTAGGATGGCAACCTAAATATGACGATATAGATCAAATAGTTCATAGTACCCTCGCTTGG
GAAATGAGTAAACAAGAATTGTTCCTCAATTCACTAGCTGGCGCTGCTTAA

Upstream 100 bases:

>100_bases
AGCTAGCTTATGACCTCTACTACATCAAGAATTACTCCCTAGCTTTAGATTTAGCGATCGCTCTCAAAACTATTCGAGTA
GTATTATTAGGTAAAGGTAG

Downstream 100 bases:

>100_bases
CTAATTCGCAATTCGTAATTAAGGACTCAACACTTTTTACTCATCACTCAATACTTTGTTCATCGAGAAAGTCTATGTGA
TCACTAAGGAACAAAATCTT

Product: UDP-glucose 4-epimerase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 336; Mature: 336

Protein sequence:

>336_residues
MNQKVLVTGGAGYIGSHVVRQLGEAGYDVVVYDNCSTGSPQAVLHGELIIGDLKNSECLSQVFHQHKFTAVLHFAASLSV
PESVARPLDYYANNTRNTLNLLRCCHDTGVNQIIFSSTAAVYGQPETAVVTESTATEPINPYGRSKLSCEWLIRDHAKAS
DLRYVILRYFNVAGAEPGGRLGQMTKDASHLIRVTCDAALKRRLGVKIFGTDFPTPDGTAIRDYIHVEDLATAHLDALVY
LEQGNSSQILNCGYGQGYSVRQVIDRVKAISGVDFPVIEAERRSGDPVCVTACTDKIRQVLGWQPKYDDIDQIVHSTLAW
EMSKQELFLNSLAGAA

Sequences:

>Translated_336_residues
MNQKVLVTGGAGYIGSHVVRQLGEAGYDVVVYDNCSTGSPQAVLHGELIIGDLKNSECLSQVFHQHKFTAVLHFAASLSV
PESVARPLDYYANNTRNTLNLLRCCHDTGVNQIIFSSTAAVYGQPETAVVTESTATEPINPYGRSKLSCEWLIRDHAKAS
DLRYVILRYFNVAGAEPGGRLGQMTKDASHLIRVTCDAALKRRLGVKIFGTDFPTPDGTAIRDYIHVEDLATAHLDALVY
LEQGNSSQILNCGYGQGYSVRQVIDRVKAISGVDFPVIEAERRSGDPVCVTACTDKIRQVLGWQPKYDDIDQIVHSTLAW
EMSKQELFLNSLAGAA
>Mature_336_residues
MNQKVLVTGGAGYIGSHVVRQLGEAGYDVVVYDNCSTGSPQAVLHGELIIGDLKNSECLSQVFHQHKFTAVLHFAASLSV
PESVARPLDYYANNTRNTLNLLRCCHDTGVNQIIFSSTAAVYGQPETAVVTESTATEPINPYGRSKLSCEWLIRDHAKAS
DLRYVILRYFNVAGAEPGGRLGQMTKDASHLIRVTCDAALKRRLGVKIFGTDFPTPDGTAIRDYIHVEDLATAHLDALVY
LEQGNSSQILNCGYGQGYSVRQVIDRVKAISGVDFPVIEAERRSGDPVCVTACTDKIRQVLGWQPKYDDIDQIVHSTLAW
EMSKQELFLNSLAGAA

Specific function: Galactose metabolism; third step. [C]

COG id: COG1087

COG function: function code M; UDP-glucose 4-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI56237023, Length=345, Percent_Identity=37.9710144927536, Blast_Score=208, Evalue=5e-54,
Organism=Homo sapiens, GI56118217, Length=345, Percent_Identity=37.9710144927536, Blast_Score=208, Evalue=5e-54,
Organism=Homo sapiens, GI189083684, Length=345, Percent_Identity=37.9710144927536, Blast_Score=208, Evalue=5e-54,
Organism=Homo sapiens, GI42516563, Length=314, Percent_Identity=25.796178343949, Blast_Score=90, Evalue=4e-18,
Organism=Homo sapiens, GI7657641, Length=322, Percent_Identity=27.0186335403727, Blast_Score=89, Evalue=5e-18,
Organism=Escherichia coli, GI1786974, Length=330, Percent_Identity=37.8787878787879, Blast_Score=207, Evalue=5e-55,
Organism=Escherichia coli, GI1790049, Length=328, Percent_Identity=27.7439024390244, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1788353, Length=370, Percent_Identity=26.2162162162162, Blast_Score=84, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI71982038, Length=346, Percent_Identity=36.1271676300578, Blast_Score=198, Evalue=3e-51,
Organism=Caenorhabditis elegans, GI71982035, Length=344, Percent_Identity=35.7558139534884, Blast_Score=196, Evalue=1e-50,
Organism=Caenorhabditis elegans, GI17539532, Length=316, Percent_Identity=24.0506329113924, Blast_Score=86, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17568069, Length=267, Percent_Identity=26.5917602996255, Blast_Score=72, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI115532424, Length=334, Percent_Identity=24.251497005988, Blast_Score=68, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI6319493, Length=319, Percent_Identity=39.4984326018809, Blast_Score=206, Evalue=4e-54,
Organism=Drosophila melanogaster, GI19923002, Length=346, Percent_Identity=37.2832369942197, Blast_Score=197, Evalue=8e-51,
Organism=Drosophila melanogaster, GI21356223, Length=315, Percent_Identity=25.7142857142857, Blast_Score=94, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR005886
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 36734; Mature: 36734

Theoretical pI: Translated: 6.43; Mature: 6.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQKVLVTGGAGYIGSHVVRQLGEAGYDVVVYDNCSTGSPQAVLHGELIIGDLKNSECLS
CCCEEEEECCCCHHHHHHHHHHHHCCCEEEEECCCCCCCCCEEEEEEEEEEECCCHHHHH
QVFHQHKFTAVLHFAASLSVPESVARPLDYYANNTRNTLNLLRCCHDTGVNQIIFSSTAA
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEECCHH
VYGQPETAVVTESTATEPINPYGRSKLSCEWLIRDHAKASDLRYVILRYFNVAGAEPGGR
CCCCCCCEEEECCCCCCCCCCCCCCCCEEEEHHHCCCCHHHHHHHHHHHHHHCCCCCCCH
LGQMTKDASHLIRVTCDAALKRRLGVKIFGTDFPTPDGTAIRDYIHVEDLATAHLDALVY
HHHHHHHHHHHEEHHHHHHHHHHCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHEEEEE
LEQGNSSQILNCGYGQGYSVRQVIDRVKAISGVDFPVIEAERRSGDPVCVTACTDKIRQV
EECCCCCCEEECCCCCCCCHHHHHHHHHHHCCCCCCEEEHHCCCCCCEEEEHHHHHHHHH
LGWQPKYDDIDQIVHSTLAWEMSKQELFLNSLAGAA
HCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNQKVLVTGGAGYIGSHVVRQLGEAGYDVVVYDNCSTGSPQAVLHGELIIGDLKNSECLS
CCCEEEEECCCCHHHHHHHHHHHHCCCEEEEECCCCCCCCCEEEEEEEEEEECCCHHHHH
QVFHQHKFTAVLHFAASLSVPESVARPLDYYANNTRNTLNLLRCCHDTGVNQIIFSSTAA
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEECCHH
VYGQPETAVVTESTATEPINPYGRSKLSCEWLIRDHAKASDLRYVILRYFNVAGAEPGGR
CCCCCCCEEEECCCCCCCCCCCCCCCCEEEEHHHCCCCHHHHHHHHHHHHHHCCCCCCCH
LGQMTKDASHLIRVTCDAALKRRLGVKIFGTDFPTPDGTAIRDYIHVEDLATAHLDALVY
HHHHHHHHHHHEEHHHHHHHHHHCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHEEEEE
LEQGNSSQILNCGYGQGYSVRQVIDRVKAISGVDFPVIEAERRSGDPVCVTACTDKIRQV
EECCCCCCEEECCCCCCCCHHHHHHHHHHHCCCCCCEEEHHCCCCCCEEEEHHHHHHHHH
LGWQPKYDDIDQIVHSTLAWEMSKQELFLNSLAGAA
HCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8026752 [H]