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The map label for this gene is lktD [H]

Identifier: 17230167

GI number: 17230167

Start: 3242898

End: 3244421

Strand: Reverse

Name: lktD [H]

Synonym: all2675

Alternate gene names: 17230167

Gene position: 3244421-3242898 (Counterclockwise)

Preceding gene: 17230168

Following gene: 17230166

Centisome position: 50.59

GC content: 44.23

Gene sequence:

>1524_bases
ATGAGTTCCAACAACGGTAACGGTCGCCTGACAACGATAACACAGGAAACGAATATTACTCCCACACCACCTAAAACATC
AAATCCTGCTGCATCCTCCTTTGAACATCCCCTGATGCTCAAACAATCCTCTGGGTGGTCACGGGGGATATTATGGACAT
TGATGTTTGTCTCAATTGCAGCAGTAGCTTGGGCTAGTGTCTCCAAAATCGAACAAGCAGTTCCAGCCCAAGGAAAACTC
GAACCTCAAGATAATGTCAACGAGGTGCAAATCCCTATCGAGGGTGTCGTCAAAACCATTCACGTCAAAGATGGACACCG
TGTTAAAGCCGGGGATTTACTTGTAAGTCTTGATCCCACCGTTTCCCAAGCGCAGGAAAATTCCTTCCAAAAAGTTCGCA
CAGTTTTAGAACAAGAAAATCAATTTTACCAAGCACAACTAAGTGGTAAAGAGGACACCTCACCTACAGTCTCCATTCCG
GCGCAATTTGTCAGCTTAACCAGAAGCCGGGCGGTATTACTTGCCGAAAATCGTCTGTTTCAAGCTCAACTTGATGGCAA
TGCTGGGGAAATGTCCTTGAGTGCCGAACAGCGACAACGGGTAAAATCTGAATTAGAAGAGTTAACATCACGAGTTACAT
CTGCTCAGTTAGAAATTGACCAATTACAAAAGCAATACAGCCAAGCAGACATTAAACTTAAATCCAACCAAGAAAAATTG
AAAGTTAATGAGCAAATTCTCACAGATATCTCCGAATTGGCGTTAGAAGGGGGAATTTCCCGCATTCAATACCTCAACCA
GCAGCAGGAAGTAGAATCCATTCGTGCAGAAATTGCACAATTGCAAGAAGAAAAGATACGCTTGCAAGCGGCTATAGCCC
AAGCCCAAGCCAAAGTCCAAAACACCAAAGACATTGATAGAAGAGATTTAACCGCCCGTATTGGCAATAATAGCCAGAGA
ATAGCTGAGATTGACAGCCAATTAAGCAAAGCCATTGTCGATAACAAAAAACGCATCGCCGAACTTGACAGCCAACTCAG
TCAAACCAATCAGGCATTAAAGTATAGTGTAGTGCGATCGCCTGTTGATGGTGTAGTCTTTGACCTCAAAGCCCACGCCC
CCGGCTTTGTGGCTAAATCCACCGAACCAGTGCTGAAAATCGTACCCCAAACTAACTTAGTAGCAAAAGTTTCCATCACC
AACCAAGACATCGGCTTTATTAGAGAAGGAATGCGCGTTGATGTCCGCATAGATTCCTTCCCCTACAGCGAATTTGGCGA
TATCAAAGGTACTTTAACCTGGATTGGTTCTGATGCCCTACCACCAACCCAACTTCAGCCATACTACACCTTCCCAGCCA
CAGTCACCCTTGACCAACAATATCTTCTCAGCCAGCAACGTAAAATTGCCCTACAGTCGGGAATGTCATTAAACGCCAAC
ATCAAAATTAGAGAACGTACTGTCATGAGCATCTTTACTGATTTCTTCAATAAAACCGGAGAAAGCCTGAAATTCGTTCG
TTAA

Upstream 100 bases:

>100_bases
GAGTAATGAGTAATGAGTAAGGAGTAATGAGTCAGAATTTCTTCCCTCACTCCCTTCTCCCCCTGCTCCCCCAATTTCCA
GTCCCCAATCCCTAAATACT

Downstream 100 bases:

>100_bases
TACTCAGTTCGTAGTAAGGACTTTAGTCCTTAGAATGAGAGGACTAAAGTCCTCGCTACAAACAAATCTGTAGAAGTATT
GAAAAGTCGGATGAAGATTA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 507; Mature: 506

Protein sequence:

>507_residues
MSSNNGNGRLTTITQETNITPTPPKTSNPAASSFEHPLMLKQSSGWSRGILWTLMFVSIAAVAWASVSKIEQAVPAQGKL
EPQDNVNEVQIPIEGVVKTIHVKDGHRVKAGDLLVSLDPTVSQAQENSFQKVRTVLEQENQFYQAQLSGKEDTSPTVSIP
AQFVSLTRSRAVLLAENRLFQAQLDGNAGEMSLSAEQRQRVKSELEELTSRVTSAQLEIDQLQKQYSQADIKLKSNQEKL
KVNEQILTDISELALEGGISRIQYLNQQQEVESIRAEIAQLQEEKIRLQAAIAQAQAKVQNTKDIDRRDLTARIGNNSQR
IAEIDSQLSKAIVDNKKRIAELDSQLSQTNQALKYSVVRSPVDGVVFDLKAHAPGFVAKSTEPVLKIVPQTNLVAKVSIT
NQDIGFIREGMRVDVRIDSFPYSEFGDIKGTLTWIGSDALPPTQLQPYYTFPATVTLDQQYLLSQQRKIALQSGMSLNAN
IKIRERTVMSIFTDFFNKTGESLKFVR

Sequences:

>Translated_507_residues
MSSNNGNGRLTTITQETNITPTPPKTSNPAASSFEHPLMLKQSSGWSRGILWTLMFVSIAAVAWASVSKIEQAVPAQGKL
EPQDNVNEVQIPIEGVVKTIHVKDGHRVKAGDLLVSLDPTVSQAQENSFQKVRTVLEQENQFYQAQLSGKEDTSPTVSIP
AQFVSLTRSRAVLLAENRLFQAQLDGNAGEMSLSAEQRQRVKSELEELTSRVTSAQLEIDQLQKQYSQADIKLKSNQEKL
KVNEQILTDISELALEGGISRIQYLNQQQEVESIRAEIAQLQEEKIRLQAAIAQAQAKVQNTKDIDRRDLTARIGNNSQR
IAEIDSQLSKAIVDNKKRIAELDSQLSQTNQALKYSVVRSPVDGVVFDLKAHAPGFVAKSTEPVLKIVPQTNLVAKVSIT
NQDIGFIREGMRVDVRIDSFPYSEFGDIKGTLTWIGSDALPPTQLQPYYTFPATVTLDQQYLLSQQRKIALQSGMSLNAN
IKIRERTVMSIFTDFFNKTGESLKFVR
>Mature_506_residues
SSNNGNGRLTTITQETNITPTPPKTSNPAASSFEHPLMLKQSSGWSRGILWTLMFVSIAAVAWASVSKIEQAVPAQGKLE
PQDNVNEVQIPIEGVVKTIHVKDGHRVKAGDLLVSLDPTVSQAQENSFQKVRTVLEQENQFYQAQLSGKEDTSPTVSIPA
QFVSLTRSRAVLLAENRLFQAQLDGNAGEMSLSAEQRQRVKSELEELTSRVTSAQLEIDQLQKQYSQADIKLKSNQEKLK
VNEQILTDISELALEGGISRIQYLNQQQEVESIRAEIAQLQEEKIRLQAAIAQAQAKVQNTKDIDRRDLTARIGNNSQRI
AEIDSQLSKAIVDNKKRIAELDSQLSQTNQALKYSVVRSPVDGVVFDLKAHAPGFVAKSTEPVLKIVPQTNLVAKVSITN
QDIGFIREGMRVDVRIDSFPYSEFGDIKGTLTWIGSDALPPTQLQPYYTFPATVTLDQQYLLSQQRKIALQSGMSLNANI
KIRERTVMSIFTDFFNKTGESLKFVR

Specific function: Involved in the transport of the Leukotoxin [H]

COG id: COG0845

COG function: function code M; Membrane-fusion protein

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003997
- InterPro:   IPR006143
- InterPro:   IPR006144
- InterPro:   IPR010129 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 56350; Mature: 56218

Theoretical pI: Translated: 7.79; Mature: 7.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSNNGNGRLTTITQETNITPTPPKTSNPAASSFEHPLMLKQSSGWSRGILWTLMFVSIA
CCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHH
AVAWASVSKIEQAVPAQGKLEPQDNVNEVQIPIEGVVKTIHVKDGHRVKAGDLLVSLDPT
HHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEHHHEEEEEEECCCCEEEECCEEEEECCC
VSQAQENSFQKVRTVLEQENQFYQAQLSGKEDTSPTVSIPAQFVSLTRSRAVLLAENRLF
HHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCEEECCHHHHHHHHCCEEEEECCCEE
QAQLDGNAGEMSLSAEQRQRVKSELEELTSRVTSAQLEIDQLQKQYSQADIKLKSNQEKL
EEEECCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCHHH
KVNEQILTDISELALEGGISRIQYLNQQQEVESIRAEIAQLQEEKIRLQAAIAQAQAKVQ
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NTKDIDRRDLTARIGNNSQRIAEIDSQLSKAIVDNKKRIAELDSQLSQTNQALKYSVVRS
CCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHC
PVDGVVFDLKAHAPGFVAKSTEPVLKIVPQTNLVAKVSITNQDIGFIREGMRVDVRIDSF
CCCCEEEEEECCCCCCEECCCCCCEEECCCCCEEEEEEECCCCHHHHHCCCEEEEEECCC
PYSEFGDIKGTLTWIGSDALPPTQLQPYYTFPATVTLDQQYLLSQQRKIALQSGMSLNAN
CCCCCCCCCEEEEEECCCCCCCCCCCCEEECCEEEEECHHHHHHHHHHHHHHCCCCCCCE
IKIRERTVMSIFTDFFNKTGESLKFVR
EEEHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
SSNNGNGRLTTITQETNITPTPPKTSNPAASSFEHPLMLKQSSGWSRGILWTLMFVSIA
CCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHH
AVAWASVSKIEQAVPAQGKLEPQDNVNEVQIPIEGVVKTIHVKDGHRVKAGDLLVSLDPT
HHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEHHHEEEEEEECCCCEEEECCEEEEECCC
VSQAQENSFQKVRTVLEQENQFYQAQLSGKEDTSPTVSIPAQFVSLTRSRAVLLAENRLF
HHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCEEECCHHHHHHHHCCEEEEECCCEE
QAQLDGNAGEMSLSAEQRQRVKSELEELTSRVTSAQLEIDQLQKQYSQADIKLKSNQEKL
EEEECCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCHHH
KVNEQILTDISELALEGGISRIQYLNQQQEVESIRAEIAQLQEEKIRLQAAIAQAQAKVQ
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NTKDIDRRDLTARIGNNSQRIAEIDSQLSKAIVDNKKRIAELDSQLSQTNQALKYSVVRS
CCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHC
PVDGVVFDLKAHAPGFVAKSTEPVLKIVPQTNLVAKVSITNQDIGFIREGMRVDVRIDSF
CCCCEEEEEECCCCCCEECCCCCCEEECCCCCEEEEEEECCCCHHHHHCCCEEEEEECCC
PYSEFGDIKGTLTWIGSDALPPTQLQPYYTFPATVTLDQQYLLSQQRKIALQSGMSLNAN
CCCCCCCCCEEEEEECCCCCCCCCCCCEEECCEEEEECHHHHHHHHHHHHHHCCCCCCCE
IKIRERTVMSIFTDFFNKTGESLKFVR
EEEHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3040588; 2914876; 2707120 [H]