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The map label for this gene is argC

Identifier: 17229990

GI number: 17229990

Start: 2998395

End: 2999363

Strand: Reverse

Name: argC

Synonym: all2498

Alternate gene names: 17229990

Gene position: 2999363-2998395 (Counterclockwise)

Preceding gene: 17229992

Following gene: 17229989

Centisome position: 46.76

GC content: 45.82

Gene sequence:

>969_bases
ATGAATAAACCGAAAATTTTTATTGATGGGGAAGCGGGAACTACAGGCTTACAGATTTACTCACGCCTCAACGAGCGAGA
TGATATTGAGCTAGTTAGTATTGCAGCATCGAAGCGCAAAGATGCGGATGAGCGAGCAAAATTGCTCAATTCCGTCGATG
TAGCCATTCTTTGTTTACCTGATGATGCAGCGCGGGAAGCTGTTAGTTTAGTTAACAGTAGTCAGGTGAAGATTCTCGAT
GCTAGCACCGCTTATCGCACGGCTCAAGGTTGGGTATATGGTTTTCCGGAAATGAACCCAGGACAGCGAGAGAAAATCGC
CAATGCTCAGTTTGTGAGCAATCCGGGGTGTTATCCTACAGGGTTTTTAGCTTGTGTACGTCCGTTAATAGCTCAAGGTA
TTCTTCCCAGTAGCTTTCCCATAACAATTAATGCGGTGTCTGGCTACTCTGGGGGTGGTAAGAGCCTGATCCAAAAGTAT
GATAGCTTCCACGAGCAGCAGAAAGGCGCAACTTCAGATTATCCCTTCGGTATCTATGGTTTACAGTTCGGTCATAAACA
CGTTAAAGAGATGCACCAGCATTCTGGGTTAGCATCACCACCATTGTTTATCCCTGCGGTGGGTGACTTCGAGCAGGGAA
TGTTGGTGCAAATACCCTTACCTCTGTGGACTTTGGACAATCCGCCATCGGGTGAAGAGATTCATCAAGCGATCGCCCAA
TACTACCAAGGGGAAAAGTTTGTGCAGGTAGCCCCATTTAAAGACCCTAGCCTGTTACGTGACGGCACATTTTTAGACGC
AACGGCAGTTAACGGTACTAATATTGTTCAGGTTTTCGTCTTCGGTAACGATAATACGAAAGAAGCACTGTTAGTGGCTC
GACTAGATAATTTGGGCAAGGGTGCATCAGGAGCAGCAGTCCAAAACCTAAATATTATGCTAGGTCTTCCAGAAGAGTTA
GGATTATGA

Upstream 100 bases:

>100_bases
TGCTGACGCAACCTACCCAACTACCAAACCATCGATTTCGGATAATTTATTTTTTGGTGTTCCCTAAGGTAAAATTCAGT
ATACAAATGCTGAAGCCATT

Downstream 100 bases:

>100_bases
CGTTATTAGTTATCAGATTAACTAATGACTAATAACTAATGACTACTGACTAATGACCAATGACTAATAAAAAACGAGTT
TGCATTATCTTAGGGACACG

Product: N-acetyl-gamma-glutamyl-phosphate reductase

Products: NA

Alternate protein names: AGPR 2; N-acetyl-glutamate semialdehyde dehydrogenase 2; NAGSA dehydrogenase 2

Number of amino acids: Translated: 322; Mature: 322

Protein sequence:

>322_residues
MNKPKIFIDGEAGTTGLQIYSRLNERDDIELVSIAASKRKDADERAKLLNSVDVAILCLPDDAAREAVSLVNSSQVKILD
ASTAYRTAQGWVYGFPEMNPGQREKIANAQFVSNPGCYPTGFLACVRPLIAQGILPSSFPITINAVSGYSGGGKSLIQKY
DSFHEQQKGATSDYPFGIYGLQFGHKHVKEMHQHSGLASPPLFIPAVGDFEQGMLVQIPLPLWTLDNPPSGEEIHQAIAQ
YYQGEKFVQVAPFKDPSLLRDGTFLDATAVNGTNIVQVFVFGNDNTKEALLVARLDNLGKGASGAAVQNLNIMLGLPEEL
GL

Sequences:

>Translated_322_residues
MNKPKIFIDGEAGTTGLQIYSRLNERDDIELVSIAASKRKDADERAKLLNSVDVAILCLPDDAAREAVSLVNSSQVKILD
ASTAYRTAQGWVYGFPEMNPGQREKIANAQFVSNPGCYPTGFLACVRPLIAQGILPSSFPITINAVSGYSGGGKSLIQKY
DSFHEQQKGATSDYPFGIYGLQFGHKHVKEMHQHSGLASPPLFIPAVGDFEQGMLVQIPLPLWTLDNPPSGEEIHQAIAQ
YYQGEKFVQVAPFKDPSLLRDGTFLDATAVNGTNIVQVFVFGNDNTKEALLVARLDNLGKGASGAAVQNLNIMLGLPEEL
GL
>Mature_322_residues
MNKPKIFIDGEAGTTGLQIYSRLNERDDIELVSIAASKRKDADERAKLLNSVDVAILCLPDDAAREAVSLVNSSQVKILD
ASTAYRTAQGWVYGFPEMNPGQREKIANAQFVSNPGCYPTGFLACVRPLIAQGILPSSFPITINAVSGYSGGGKSLIQKY
DSFHEQQKGATSDYPFGIYGLQFGHKHVKEMHQHSGLASPPLFIPAVGDFEQGMLVQIPLPLWTLDNPPSGEEIHQAIAQ
YYQGEKFVQVAPFKDPSLLRDGTFLDATAVNGTNIVQVFVFGNDNTKEALLVARLDNLGKGASGAAVQNLNIMLGLPEEL
GL

Specific function: Arginine biosynthesis; third step. [C]

COG id: COG0002

COG function: function code E; Acetylglutamate semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAGSA dehydrogenase family. Type 2 subfamily

Homologues:

Organism=Escherichia coli, GI1790396, Length=291, Percent_Identity=28.1786941580756, Blast_Score=66, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6320913, Length=280, Percent_Identity=30.7142857142857, Blast_Score=90, Evalue=5e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ARGC2_NOSS1 (P54894)

Other databases:

- EMBL:   X65511
- EMBL:   BA000019
- PIR:   AC2118
- PIR:   S24753
- RefSeq:   NP_486538.1
- ProteinModelPortal:   P54894
- SMR:   P54894
- STRING:   P54894
- GeneID:   1106095
- GenomeReviews:   BA000019_GR
- KEGG:   ana:all2498
- NMPDR:   fig|103690.1.peg.2805
- eggNOG:   COG0002
- HOGENOM:   HBG294213
- OMA:   PIFVPSV
- ProtClustDB:   PRK11863
- BioCyc:   NSP103690:ALL2498-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01110
- InterPro:   IPR023013
- InterPro:   IPR010136
- InterPro:   IPR016040
- InterPro:   IPR000534
- Gene3D:   G3DSA:3.40.50.720
- SMART:   SM00859
- TIGRFAMs:   TIGR01851

Pfam domain/function: PF01118 Semialdhyde_dh

EC number: =1.2.1.38

Molecular weight: Translated: 34823; Mature: 34823

Theoretical pI: Translated: 5.16; Mature: 5.16

Prosite motif: PS01224 ARGC

Important sites: ACT_SITE 117-117

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKPKIFIDGEAGTTGLQIYSRLNERDDIELVSIAASKRKDADERAKLLNSVDVAILCLP
CCCCEEEEECCCCCHHHHHHHHCCCCCCEEEEEEEHHCCCCHHHHHHHHCCCCEEEEECC
DDAAREAVSLVNSSQVKILDASTAYRTAQGWVYGFPEMNPGQREKIANAQFVSNPGCYPT
CHHHHHHHHHHCCCCEEEEECCCHHEECCCEEEECCCCCCCHHHHHCCCEEECCCCCCCH
GFLACVRPLIAQGILPSSFPITINAVSGYSGGGKSLIQKYDSFHEQQKGATSDYPFGIYG
HHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEE
LQFGHKHVKEMHQHSGLASPPLFIPAVGDFEQGMLVQIPLPLWTLDNPPSGEEIHQAIAQ
HHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCEEEEECCCEEECCCCCCHHHHHHHHHH
YYQGEKFVQVAPFKDPSLLRDGTFLDATAVNGTNIVQVFVFGNDNTKEALLVARLDNLGK
HHCCCEEEEEECCCCCCHHCCCCEEEEEECCCCCEEEEEEECCCCCHHHEEEEEHHHCCC
GASGAAVQNLNIMLGLPEELGL
CCCCCEEEEEEEEEECCHHHCC
>Mature Secondary Structure
MNKPKIFIDGEAGTTGLQIYSRLNERDDIELVSIAASKRKDADERAKLLNSVDVAILCLP
CCCCEEEEECCCCCHHHHHHHHCCCCCCEEEEEEEHHCCCCHHHHHHHHCCCCEEEEECC
DDAAREAVSLVNSSQVKILDASTAYRTAQGWVYGFPEMNPGQREKIANAQFVSNPGCYPT
CHHHHHHHHHHCCCCEEEEECCCHHEECCCEEEECCCCCCCHHHHHCCCEEECCCCCCCH
GFLACVRPLIAQGILPSSFPITINAVSGYSGGGKSLIQKYDSFHEQQKGATSDYPFGIYG
HHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEE
LQFGHKHVKEMHQHSGLASPPLFIPAVGDFEQGMLVQIPLPLWTLDNPPSGEEIHQAIAQ
HHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCEEEEECCCEEECCCCCCHHHHHHHHHH
YYQGEKFVQVAPFKDPSLLRDGTFLDATAVNGTNIVQVFVFGNDNTKEALLVARLDNLGK
HHCCCEEEEEECCCCCCHHCCCCEEEEEECCCCCEEEEEEECCCCCHHHEEEEEHHHCCC
GASGAAVQNLNIMLGLPEELGL
CCCCCEEEEEEEEEECCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1406250; 7929012; 11759840