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The map label for this gene is wecB [C]

Identifier: 17229989

GI number: 17229989

Start: 2997223

End: 2998335

Strand: Reverse

Name: wecB [C]

Synonym: all2497

Alternate gene names: 17229989

Gene position: 2998335-2997223 (Counterclockwise)

Preceding gene: 17229990

Following gene: 17229983

Centisome position: 46.75

GC content: 44.12

Gene sequence:

>1113_bases
ATGACTAATAAAAAACGAGTTTGCATTATCTTAGGGACACGCCCCGAAGCCATTAAACTAGCTCCGGTAATTCAGGTCTT
CCAAAAATCTCCAGACTTTGAGCTGCAAGTGATTTTAACTGGACAGCATCGTGAGATGGTGGAACAAGTGATGCAGCTGT
TCAACCTCAAGGCGGATTATGACCTAGAGATTATGCAGCCTCAACAGTCTCTAAGTGATATTACTTGTCGTAGTTTACGC
GGTTTGGAAGGTTTATTTATTCAAAATAAGCCAGATTTGGTGTTGGTACAAGGAGATACGACAACAGCTTTTGCGGCAAG
TTTAGCAGCCTTTTACCAAAAAATTCCTGTAGGTCATGTGGAAGCTGGGTTGAGAACAGATGAATTATTTAATCCTTACC
CAGAAGAAGCTAATCGGCGGTTGATTTCCCAAATTACCCAGTTGCACTTTGCACCAACGACTTTGGCTGTGGAAAACTTG
CAGCGTTCTGGTGTTTTAGGGGAAATTCACTTAACTGGTAATACTGTAATCGATGCTTTATTATATGTAGCCGCCAATGC
ACCAGCTTGCGATGTAGCTGGTTTAAACTGGGATGAGTATCGTGTGCTATTAGCTACAGTCCATCGGCGGGAAAATTGGG
GTGAGCCACTACAGGCGATCGCTCAAGGATTTTTGCAGATATTAGATAAGTTTCCTGATACCGCCTTGCTCTTACCCTTA
CACCGCAATCCCACAGTCCGCGAACCATTGCAAGCATTACTAGGGAATCATCCACGGGTATTTTTAACAGAACCCCTTGA
TTATGCCGAATTGGTAGGAGCAATCGGGCGATCGCACTTTTTATTGACTGATTCTGGTGGTTTGCAAGAAGAAGCGCCTA
GTCTGGGTAAACCAGTTCTGGTTCTCAGGGAAACGACAGAAAGACCGGAAGCAGTCACGGCGGGTACAGCTAAACTTGTG
GGTACTGACAGCAAAACTATTACCTCTGCTGCCAGTGAGTTATTGAGTAATCCAGTAGCTTATGATGCGATGGCTAATGC
AATTAATCCCTTTGGTGATGGTCATGCAGCCGAACGCATCTTAGAAATTGTGCAGAATTACTTCACTAGATGA

Upstream 100 bases:

>100_bases
TAAATATTATGCTAGGTCTTCCAGAAGAGTTAGGATTATGACGTTATTAGTTATCAGATTAACTAATGACTAATAACTAA
TGACTACTGACTAATGACCA

Downstream 100 bases:

>100_bases
GGTAGTGGCGATCGCCCTTACCCTCCGCCGAGGATCTACCCGACTCCGAAGAATTACGTAGATTAGGGATAGACTAAATG
AGGCTAAATGGATTCGTGAT

Product: UDP-N-acetyl glucosamine-2-epimerase

Products: NA

Alternate protein names: UDP-GlcNAc-2-epimerase [H]

Number of amino acids: Translated: 370; Mature: 369

Protein sequence:

>370_residues
MTNKKRVCIILGTRPEAIKLAPVIQVFQKSPDFELQVILTGQHREMVEQVMQLFNLKADYDLEIMQPQQSLSDITCRSLR
GLEGLFIQNKPDLVLVQGDTTTAFAASLAAFYQKIPVGHVEAGLRTDELFNPYPEEANRRLISQITQLHFAPTTLAVENL
QRSGVLGEIHLTGNTVIDALLYVAANAPACDVAGLNWDEYRVLLATVHRRENWGEPLQAIAQGFLQILDKFPDTALLLPL
HRNPTVREPLQALLGNHPRVFLTEPLDYAELVGAIGRSHFLLTDSGGLQEEAPSLGKPVLVLRETTERPEAVTAGTAKLV
GTDSKTITSAASELLSNPVAYDAMANAINPFGDGHAAERILEIVQNYFTR

Sequences:

>Translated_370_residues
MTNKKRVCIILGTRPEAIKLAPVIQVFQKSPDFELQVILTGQHREMVEQVMQLFNLKADYDLEIMQPQQSLSDITCRSLR
GLEGLFIQNKPDLVLVQGDTTTAFAASLAAFYQKIPVGHVEAGLRTDELFNPYPEEANRRLISQITQLHFAPTTLAVENL
QRSGVLGEIHLTGNTVIDALLYVAANAPACDVAGLNWDEYRVLLATVHRRENWGEPLQAIAQGFLQILDKFPDTALLLPL
HRNPTVREPLQALLGNHPRVFLTEPLDYAELVGAIGRSHFLLTDSGGLQEEAPSLGKPVLVLRETTERPEAVTAGTAKLV
GTDSKTITSAASELLSNPVAYDAMANAINPFGDGHAAERILEIVQNYFTR
>Mature_369_residues
TNKKRVCIILGTRPEAIKLAPVIQVFQKSPDFELQVILTGQHREMVEQVMQLFNLKADYDLEIMQPQQSLSDITCRSLRG
LEGLFIQNKPDLVLVQGDTTTAFAASLAAFYQKIPVGHVEAGLRTDELFNPYPEEANRRLISQITQLHFAPTTLAVENLQ
RSGVLGEIHLTGNTVIDALLYVAANAPACDVAGLNWDEYRVLLATVHRRENWGEPLQAIAQGFLQILDKFPDTALLLPLH
RNPTVREPLQALLGNHPRVFLTEPLDYAELVGAIGRSHFLLTDSGGLQEEAPSLGKPVLVLRETTERPEAVTAGTAKLVG
TDSKTITSAASELLSNPVAYDAMANAINPFGDGHAAERILEIVQNYFTR

Specific function: Catalyzes The Reversible Epimerization At C-2 Of UDP-N- Acetylglucosamine (UDP-Glcnac) And Thereby Provides Bacteria With UDP-N-Acetylmannosamine (UDP-Mannac), The Activated Donor Of Mannac Residues. Also Involved In Bacteriophage N4 Adsorption. [C]

COG id: COG0381

COG function: function code M; UDP-N-acetylglucosamine 2-epimerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-N-acetylglucosamine 2-epimerase family [H]

Homologues:

Organism=Escherichia coli, GI48994967, Length=376, Percent_Identity=50, Blast_Score=353, Evalue=1e-98,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003331 [H]

Pfam domain/function: PF02350 Epimerase_2 [H]

EC number: =5.1.3.14 [H]

Molecular weight: Translated: 40745; Mature: 40614

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNKKRVCIILGTRPEAIKLAPVIQVFQKSPDFELQVILTGQHREMVEQVMQLFNLKADY
CCCCCEEEEEECCCCCCCHHHHHHHHHHCCCCCEEEEEEECCHHHHHHHHHHHHCCCCCC
DLEIMQPQQSLSDITCRSLRGLEGLFIQNKPDLVLVQGDTTTAFAASLAAFYQKIPVGHV
CEEEECCHHHHHHHHHHHHCCCCCEEECCCCCEEEEECCCHHHHHHHHHHHHHHCCCCHH
EAGLRTDELFNPYPEEANRRLISQITQLHFAPTTLAVENLQRSGVLGEIHLTGNTVIDAL
HCCCCHHHHCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCEEEEEECCHHHHHHH
LYVAANAPACDVAGLNWDEYRVLLATVHRRENWGEPLQAIAQGFLQILDKFPDTALLLPL
HHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCEEEEEE
HRNPTVREPLQALLGNHPRVFLTEPLDYAELVGAIGRSHFLLTDSGGLQEEAPSLGKPVL
CCCCCHHHHHHHHHCCCCEEEEECCCCHHHHHHHHCCCEEEEECCCCCHHCCCCCCCCEE
VLRETTERPEAVTAGTAKLVGTDSKTITSAASELLSNPVAYDAMANAINPFGDGHAAERI
EEECCCCCCCCEECCCEEEECCCCHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCHHHHHH
LEIVQNYFTR
HHHHHHHHCC
>Mature Secondary Structure 
TNKKRVCIILGTRPEAIKLAPVIQVFQKSPDFELQVILTGQHREMVEQVMQLFNLKADY
CCCCEEEEEECCCCCCCHHHHHHHHHHCCCCCEEEEEEECCHHHHHHHHHHHHCCCCCC
DLEIMQPQQSLSDITCRSLRGLEGLFIQNKPDLVLVQGDTTTAFAASLAAFYQKIPVGHV
CEEEECCHHHHHHHHHHHHCCCCCEEECCCCCEEEEECCCHHHHHHHHHHHHHHCCCCHH
EAGLRTDELFNPYPEEANRRLISQITQLHFAPTTLAVENLQRSGVLGEIHLTGNTVIDAL
HCCCCHHHHCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCEEEEEECCHHHHHHH
LYVAANAPACDVAGLNWDEYRVLLATVHRRENWGEPLQAIAQGFLQILDKFPDTALLLPL
HHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCEEEEEE
HRNPTVREPLQALLGNHPRVFLTEPLDYAELVGAIGRSHFLLTDSGGLQEEAPSLGKPVL
CCCCCHHHHHHHHHCCCCEEEEECCCCHHHHHHHHCCCEEEEECCCCCHHCCCCCCCCEE
VLRETTERPEAVTAGTAKLVGTDSKTITSAASELLSNPVAYDAMANAINPFGDGHAAERI
EEECCCCCCCCEECCCEEEECCCCHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCHHHHHH
LEIVQNYFTR
HHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]