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The map label for this gene is rsgA1

Identifier: 17229941

GI number: 17229941

Start: 2944744

End: 2945856

Strand: Direct

Name: rsgA1

Synonym: alr2449

Alternate gene names: 17229941

Gene position: 2944744-2945856 (Clockwise)

Preceding gene: 17229940

Following gene: 17229942

Centisome position: 45.91

GC content: 46.99

Gene sequence:

>1113_bases
ATGAGAGTTTTCACCACTGGACAGTTATTGGGTACGGTTGTAGCCGTGCAGGCCAATTTTTACAAAGTACAGCTAGACCA
AGAGGTAAGGGAGCAAGGGAGCAGAGGTGCAGGGGAGGAGGTGCATTTAGATTCTCCTCTACCCCTCTGTCCCCTGTCTC
TTCTTCTTTGCACTCGCAGAACCCGGTTGAAAAAAATCGGGCAACAGGTGATGGTGGGCGATCGCGTGGTCGTAGAGGAG
CCAGATTGGGCTGGGGGACGGGGGGCGATCGCTGATGTTCTATCGCGGCAAACCCAGTTAGATAGGCCACCAATCGCCAA
TGCTGACCAAATCCTGCTGGTTTTTGCTGTGGCTGACCCTCCCCTCGAACCCTATCAACTTAGCCGATTTCTCGTGAAGG
CGGAAACTACTGGACTAGATGTGGTTTTATGTTTGAATAAAAGCGATCTAGTTTCACCAGAAATACAGCAACAAATTAGC
GATCGCCTATTAGCTTGGGGTTATCAACCCTTATTTATTAGCGTCGAAAATCAGATAAATATTGACCAAATAGCCAAATA
TCTCAGCAATAAAATTACCGTAGTTGCTGGCCCTTCTGGTGTGGGTAAATCCAGCTTGATTAATGCTCTGATTCCCAACA
TTAACCTGCGCGTGGGGGAAGTTTCCGGTAAACTGGCTCGTGGTCGTCATACCACCCGCCATGTAGAGTTATTTGAGTTA
CCCAACGGTGGTTTACTGGCAGATACGCCGGGATTTAATCAGCCTGATGTGGATTGTAGTCCAGAAGAATTAGTACATTA
TTTCCCAGAAGCCAGAGAACGTTTAGCGATTGCTAGTTGTCGGTTTAACGACTGCTCACATCGAGACGAGCCAGATTGTG
CTGTGCGTGGTGATTGGGAACGATATGAACATTATCTAGAATTTTTAGCAGATGCGATCGCCAGGCAAACTCAGCTTTAC
CAACAAGCCGATCCCGAATCTACTTTGAAGCTCAAAACCAAAGGCAAAGGTCAGAGTCAATACGAACCTAAACTAGAAAG
TAAAAAATATCGCCGAACCTCCCGACGCACTCAAGTACAAGGCTTGCAAGATTTGTATCAAGAGGAAGAATAG

Upstream 100 bases:

>100_bases
AAGTTCCTGATAGCTTGACAATGGCAGGTTATCAGGTAGAACAAATCACAGACTGTACTGGCTATTTTTCTTTATTAATC
CGCCGTCCTGTAACTGCCCA

Downstream 100 bases:

>100_bases
GGACAATTAAGGGGCAGGGAGCAGGGAGCAGGGAGAATAACTTTAGCCAGCACTCATGGCTCCCCTCTCATCAGTCAACA
GCCAACAGTCATCACTTTTA

Product: ribosome-associated GTPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 370; Mature: 370

Protein sequence:

>370_residues
MRVFTTGQLLGTVVAVQANFYKVQLDQEVREQGSRGAGEEVHLDSPLPLCPLSLLLCTRRTRLKKIGQQVMVGDRVVVEE
PDWAGGRGAIADVLSRQTQLDRPPIANADQILLVFAVADPPLEPYQLSRFLVKAETTGLDVVLCLNKSDLVSPEIQQQIS
DRLLAWGYQPLFISVENQINIDQIAKYLSNKITVVAGPSGVGKSSLINALIPNINLRVGEVSGKLARGRHTTRHVELFEL
PNGGLLADTPGFNQPDVDCSPEELVHYFPEARERLAIASCRFNDCSHRDEPDCAVRGDWERYEHYLEFLADAIARQTQLY
QQADPESTLKLKTKGKGQSQYEPKLESKKYRRTSRRTQVQGLQDLYQEEE

Sequences:

>Translated_370_residues
MRVFTTGQLLGTVVAVQANFYKVQLDQEVREQGSRGAGEEVHLDSPLPLCPLSLLLCTRRTRLKKIGQQVMVGDRVVVEE
PDWAGGRGAIADVLSRQTQLDRPPIANADQILLVFAVADPPLEPYQLSRFLVKAETTGLDVVLCLNKSDLVSPEIQQQIS
DRLLAWGYQPLFISVENQINIDQIAKYLSNKITVVAGPSGVGKSSLINALIPNINLRVGEVSGKLARGRHTTRHVELFEL
PNGGLLADTPGFNQPDVDCSPEELVHYFPEARERLAIASCRFNDCSHRDEPDCAVRGDWERYEHYLEFLADAIARQTQLY
QQADPESTLKLKTKGKGQSQYEPKLESKKYRRTSRRTQVQGLQDLYQEEE
>Mature_370_residues
MRVFTTGQLLGTVVAVQANFYKVQLDQEVREQGSRGAGEEVHLDSPLPLCPLSLLLCTRRTRLKKIGQQVMVGDRVVVEE
PDWAGGRGAIADVLSRQTQLDRPPIANADQILLVFAVADPPLEPYQLSRFLVKAETTGLDVVLCLNKSDLVSPEIQQQIS
DRLLAWGYQPLFISVENQINIDQIAKYLSNKITVVAGPSGVGKSSLINALIPNINLRVGEVSGKLARGRHTTRHVELFEL
PNGGLLADTPGFNQPDVDCSPEELVHYFPEARERLAIASCRFNDCSHRDEPDCAVRGDWERYEHYLEFLADAIARQTQLY
QQADPESTLKLKTKGKGQSQYEPKLESKKYRRTSRRTQVQGLQDLYQEEE

Specific function: May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover

COG id: COG1162

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 engC GTPase domain

Homologues:

Organism=Escherichia coli, GI87082381, Length=292, Percent_Identity=30.4794520547945, Blast_Score=120, Evalue=1e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RSGA1_NOSS1 (Q8YUA3)

Other databases:

- EMBL:   BA000019
- PIR:   AB2112
- RefSeq:   NP_486489.1
- ProteinModelPortal:   Q8YUA3
- SMR:   Q8YUA3
- STRING:   Q8YUA3
- GeneID:   1106046
- GenomeReviews:   BA000019_GR
- KEGG:   ana:alr2449
- NMPDR:   fig|103690.1.peg.2756
- eggNOG:   COG1162
- HOGENOM:   HBG652450
- OMA:   RGDWERY
- PhylomeDB:   Q8YUA3
- ProtClustDB:   PRK12289
- BioCyc:   NSP103690:ALR2449-MONOMER
- HAMAP:   MF_01820
- InterPro:   IPR010914
- InterPro:   IPR016027
- InterPro:   IPR004881
- TIGRFAMs:   TIGR00157

Pfam domain/function: PF03193 DUF258; SSF50249 Nucleic_acid_OB

EC number: NA

Molecular weight: Translated: 41448; Mature: 41448

Theoretical pI: Translated: 5.75; Mature: 5.75

Prosite motif: PS50936 ENGC_GTPASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVFTTGQLLGTVVAVQANFYKVQLDQEVREQGSRGAGEEVHLDSPLPLCPLSLLLCTRR
CCEEECHHHHHHHHHEECCEEEEEECHHHHHCCCCCCCCEEEECCCCCHHHHHHHHHHHH
TRLKKIGQQVMVGDRVVVEEPDWAGGRGAIADVLSRQTQLDRPPIANADQILLVFAVADP
HHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCC
PLEPYQLSRFLVKAETTGLDVVLCLNKSDLVSPEIQQQISDRLLAWGYQPLFISVENQIN
CCCHHHHHHHHHEECCCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCC
IDQIAKYLSNKITVVAGPSGVGKSSLINALIPNINLRVGEVSGKLARGRHTTRHVELFEL
HHHHHHHHCCCEEEEECCCCCCHHHHHHHHCCCCEEEEECCCCCHHCCCCCCEEEEEEEC
PNGGLLADTPGFNQPDVDCSPEELVHYFPEARERLAIASCRFNDCSHRDEPDCAVRGDWE
CCCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHHEEHHHCCCCCCCCCCCCCCEECCCHH
RYEHYLEFLADAIARQTQLYQQADPESTLKLKTKGKGQSQYEPKLESKKYRRTSRRTQVQ
HHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHH
GLQDLYQEEE
HHHHHHCCCC
>Mature Secondary Structure
MRVFTTGQLLGTVVAVQANFYKVQLDQEVREQGSRGAGEEVHLDSPLPLCPLSLLLCTRR
CCEEECHHHHHHHHHEECCEEEEEECHHHHHCCCCCCCCEEEECCCCCHHHHHHHHHHHH
TRLKKIGQQVMVGDRVVVEEPDWAGGRGAIADVLSRQTQLDRPPIANADQILLVFAVADP
HHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCC
PLEPYQLSRFLVKAETTGLDVVLCLNKSDLVSPEIQQQISDRLLAWGYQPLFISVENQIN
CCCHHHHHHHHHEECCCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCC
IDQIAKYLSNKITVVAGPSGVGKSSLINALIPNINLRVGEVSGKLARGRHTTRHVELFEL
HHHHHHHHCCCEEEEECCCCCCHHHHHHHHCCCCEEEEECCCCCHHCCCCCCEEEEEEEC
PNGGLLADTPGFNQPDVDCSPEELVHYFPEARERLAIASCRFNDCSHRDEPDCAVRGDWE
CCCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHHEEHHHCCCCCCCCCCCCCCEECCCHH
RYEHYLEFLADAIARQTQLYQQADPESTLKLKTKGKGQSQYEPKLESKKYRRTSRRTQVQ
HHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHH
GLQDLYQEEE
HHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: GTP [C]

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11759840