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The map label for this gene is glmM [H]

Identifier: 17229853

GI number: 17229853

Start: 2842854

End: 2845382

Strand: Direct

Name: glmM [H]

Synonym: alr2361

Alternate gene names: 17229853

Gene position: 2842854-2845382 (Clockwise)

Preceding gene: 17229851

Following gene: 17229855

Centisome position: 44.32

GC content: 46.18

Gene sequence:

>2529_bases
ATGCGTGCAGTGCTGATGGCAGGCGGTTCCGGAACGCGACTTCGCCCGTTAACTTGTGATCTACCAAAACCAATGGTACC
GATCCTCAATCGCCCAATTGCCGAACATATCATTAATCTCCTCAAGAGACATCACATTACAGAAGTTATTGCCACCTTGC
ATTATCTACCTGATGTCTTGCGAGACTATTTTCAAGATGGCGGTGATTTTGGTGTGCAGATGACCTACGCCGTCGAAGAA
GACCAGCCTCTGGGAACAGCAGGTTGCGTGAAAAACATTGCCGAACTTCTGGATGAAACTTTTTTAGTAATTAGCGGTGA
TAGCATCACAGATTTTGATTTAGGAGAAGCGATCGCTTTTCACAAACAAAAACAGTCAAAAGCTACTCTAATTTTAACAA
GGGTTCCTAACCCTATAGAATTTGGTGTCGTAATCACCGATGAAGCAGGCAAAATTAAACGCTTTTTAGAAAAACCATCT
ACCAGCGAAATTTTTTCTGATACCGTTAATACTGGAACATACATTCTGGAACCAGAAGTTTTAGAATATCTCCCATCCAA
TACAGAATGTGACTTTTCTAAAGATTTATTTCCTCTGCTGCTGGCCAAAGACGAGCCAATGTATGGTTACGTTGCCGAAG
GTTACTGGTGCGATGTCGGACACTTAGATGCTTATCGGGAAGCTCAGTATGATGGTTTAGATCGTAAGGTAAAACTAGAT
TTTGCTTACAGGGAAAATTCTCCTGGCTTGTGGATAGGACAAAATACTTATATTGACCCCTCTGCACATATAGAAGCCCC
AGCCGTGATAGGTAACAATTGCCGTATCGGTGCGAGAGTACAAATTGAGGCTGGAACTGTGATTGGGGATAATGTCACCA
TTGGTGCTGATGCCAATCTCAAGCGTCCGATTGTGTGGAATGGGGCAATTATTGGGGAAGAAGCCCAGTTGAGTGCTTGT
GTAATCTCTCGTGGAACCCGTGTAGACCGCCGCGCCCATGTGTTAGAAGCCTCTGTAGTGGGTTCTTTGTCCACGGTTGG
GGAAGAAGCCCAGATTAGCCCCGGTGTCAGAGTTTGGCCTAGTAAAAAGATTGAATCAGGGGCAATTTTAAACATCAACT
TGATTTGGGGTAACACCGCCCAACGAAACTTATTTGGGCAACGTGGGGTACAAGGATTAGCAAATATCGATATCAGCCCA
GAGTTTGCGGTGAAGTTAGGGGCTGCTTATGGTTCTACTTTAAAACCTGGTGCAAAAGTAACTGTGTCCCGTGACCAACG
CAATGTTTCCCGCATGGTGACGCGATCGCTCATTGCAGGTTTAATGTCTGTAGGTGTCGATATTCAAAACCTCGATGCAA
CAGCCATCCCCATCGCCCGGACAGTTATACCCACAATGGGAGTTGCGGGAGGGATTCATGTACGAGTACACCCCGATCGC
GCCGACTATATCCTGATAGAATTCATGGATCATAAGGGGATTAATATCTCCAAAGCCCAAGAAAAGAAAATTGAAGGGGC
TTATTTCAAGGAAGATATGCGCCGGGCTTTAACTCATGAAATTGGTGATGTGGCTTACCCCAGCCAAGTTATTGACCTTT
ACTGCACAGCTTTTGAGAAACTGTTGAATGTTTCTACCCTCAACAACAGCCGGGCAAAAGTCGTAATTGACTATGTTTAT
GCTGTATCTGGGGCTGTTTTACCCCAAATGCTAGATAAATTTGGTGCTGACGCAGTGGTACTAAATGCCAGTCTGAATAA
AAATGCTGTCACCACAACCGATAGGGAAACACTACTGACTCAGCTAGGTCATGTGGTGGAAGCGTTGAAGGCTAATTTCG
GTGTCCAAGTCTCCGCTAACGGCGAACAGCTCATTTTAGTTGACGAATCAGGCTACCCCATTCGCGGCGAACTATTAACC
GCACTGATGGTAGATATGATTTTGACTTCCAACCCCAGAGGGACGGTAGTTGTGCCGGTTCATGCTTCCAGTGCGGTGGA
ACAAGTCGCCCGTCGCCATGATGGTAGGATCATTCGCACCAAAGCCAATGCGACAGCCTTGATGGAAGCTTGTCAGAAAA
ATCCCAATGTGGTGTTAGGTGGTAGCGGCGAAACTGGCTTTATCTTTCCCCAACTGCATCCGGGGTTTGACTCCATGTTC
TGCATTGCCAAAATCATTGAAATGTTAACCATACAAGAGCGATCGCTGGCTACTGTACGATCAGAATTACCCCGTGTGAT
TTACAGAACCCACACCATCCGTTGTCCCTGGTCGGCTAAAGGTGCATTGATGCGCTACTTAGTGGAAACTCACCCAGCCC
AAAACCTCGAACTCATCGATGGGGTGAAGATTCGCCAACCCTTTGATGATAGTTGGTTGTTAGTTTTACCAGATGCTAGT
GAACCATTAGTACATTTGTATGCGAACAGTCACGAGCGCGACTGGGTAGATGAGACGGTGAGGGATTACCGTTCCCGTGT
GCAGAGTTTCGTAGAGAGACAGCAGGAATATCATCCGGCGGAAGTGTGA

Upstream 100 bases:

>100_bases
GGTGTTTCAAATATCAGTATCCATAGGAAACTAGATAAAAACACAATATACTCTCACGGGTTTAAACGCAGCTAACGCTG
CAAAAAGTTAAGGAGGATTT

Downstream 100 bases:

>100_bases
ATAGTTGATAATATGGGCGGTAATGGGTAATAGCTAATTGGTAATTGATTTTTACCATTAGCCATTACCCGTTACTGATT
GCCATCCACACAGAATAAAT

Product: mannose-1-phosphate guanyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 842; Mature: 842

Protein sequence:

>842_residues
MRAVLMAGGSGTRLRPLTCDLPKPMVPILNRPIAEHIINLLKRHHITEVIATLHYLPDVLRDYFQDGGDFGVQMTYAVEE
DQPLGTAGCVKNIAELLDETFLVISGDSITDFDLGEAIAFHKQKQSKATLILTRVPNPIEFGVVITDEAGKIKRFLEKPS
TSEIFSDTVNTGTYILEPEVLEYLPSNTECDFSKDLFPLLLAKDEPMYGYVAEGYWCDVGHLDAYREAQYDGLDRKVKLD
FAYRENSPGLWIGQNTYIDPSAHIEAPAVIGNNCRIGARVQIEAGTVIGDNVTIGADANLKRPIVWNGAIIGEEAQLSAC
VISRGTRVDRRAHVLEASVVGSLSTVGEEAQISPGVRVWPSKKIESGAILNINLIWGNTAQRNLFGQRGVQGLANIDISP
EFAVKLGAAYGSTLKPGAKVTVSRDQRNVSRMVTRSLIAGLMSVGVDIQNLDATAIPIARTVIPTMGVAGGIHVRVHPDR
ADYILIEFMDHKGINISKAQEKKIEGAYFKEDMRRALTHEIGDVAYPSQVIDLYCTAFEKLLNVSTLNNSRAKVVIDYVY
AVSGAVLPQMLDKFGADAVVLNASLNKNAVTTTDRETLLTQLGHVVEALKANFGVQVSANGEQLILVDESGYPIRGELLT
ALMVDMILTSNPRGTVVVPVHASSAVEQVARRHDGRIIRTKANATALMEACQKNPNVVLGGSGETGFIFPQLHPGFDSMF
CIAKIIEMLTIQERSLATVRSELPRVIYRTHTIRCPWSAKGALMRYLVETHPAQNLELIDGVKIRQPFDDSWLLVLPDAS
EPLVHLYANSHERDWVDETVRDYRSRVQSFVERQQEYHPAEV

Sequences:

>Translated_842_residues
MRAVLMAGGSGTRLRPLTCDLPKPMVPILNRPIAEHIINLLKRHHITEVIATLHYLPDVLRDYFQDGGDFGVQMTYAVEE
DQPLGTAGCVKNIAELLDETFLVISGDSITDFDLGEAIAFHKQKQSKATLILTRVPNPIEFGVVITDEAGKIKRFLEKPS
TSEIFSDTVNTGTYILEPEVLEYLPSNTECDFSKDLFPLLLAKDEPMYGYVAEGYWCDVGHLDAYREAQYDGLDRKVKLD
FAYRENSPGLWIGQNTYIDPSAHIEAPAVIGNNCRIGARVQIEAGTVIGDNVTIGADANLKRPIVWNGAIIGEEAQLSAC
VISRGTRVDRRAHVLEASVVGSLSTVGEEAQISPGVRVWPSKKIESGAILNINLIWGNTAQRNLFGQRGVQGLANIDISP
EFAVKLGAAYGSTLKPGAKVTVSRDQRNVSRMVTRSLIAGLMSVGVDIQNLDATAIPIARTVIPTMGVAGGIHVRVHPDR
ADYILIEFMDHKGINISKAQEKKIEGAYFKEDMRRALTHEIGDVAYPSQVIDLYCTAFEKLLNVSTLNNSRAKVVIDYVY
AVSGAVLPQMLDKFGADAVVLNASLNKNAVTTTDRETLLTQLGHVVEALKANFGVQVSANGEQLILVDESGYPIRGELLT
ALMVDMILTSNPRGTVVVPVHASSAVEQVARRHDGRIIRTKANATALMEACQKNPNVVLGGSGETGFIFPQLHPGFDSMF
CIAKIIEMLTIQERSLATVRSELPRVIYRTHTIRCPWSAKGALMRYLVETHPAQNLELIDGVKIRQPFDDSWLLVLPDAS
EPLVHLYANSHERDWVDETVRDYRSRVQSFVERQQEYHPAEV
>Mature_842_residues
MRAVLMAGGSGTRLRPLTCDLPKPMVPILNRPIAEHIINLLKRHHITEVIATLHYLPDVLRDYFQDGGDFGVQMTYAVEE
DQPLGTAGCVKNIAELLDETFLVISGDSITDFDLGEAIAFHKQKQSKATLILTRVPNPIEFGVVITDEAGKIKRFLEKPS
TSEIFSDTVNTGTYILEPEVLEYLPSNTECDFSKDLFPLLLAKDEPMYGYVAEGYWCDVGHLDAYREAQYDGLDRKVKLD
FAYRENSPGLWIGQNTYIDPSAHIEAPAVIGNNCRIGARVQIEAGTVIGDNVTIGADANLKRPIVWNGAIIGEEAQLSAC
VISRGTRVDRRAHVLEASVVGSLSTVGEEAQISPGVRVWPSKKIESGAILNINLIWGNTAQRNLFGQRGVQGLANIDISP
EFAVKLGAAYGSTLKPGAKVTVSRDQRNVSRMVTRSLIAGLMSVGVDIQNLDATAIPIARTVIPTMGVAGGIHVRVHPDR
ADYILIEFMDHKGINISKAQEKKIEGAYFKEDMRRALTHEIGDVAYPSQVIDLYCTAFEKLLNVSTLNNSRAKVVIDYVY
AVSGAVLPQMLDKFGADAVVLNASLNKNAVTTTDRETLLTQLGHVVEALKANFGVQVSANGEQLILVDESGYPIRGELLT
ALMVDMILTSNPRGTVVVPVHASSAVEQVARRHDGRIIRTKANATALMEACQKNPNVVLGGSGETGFIFPQLHPGFDSMF
CIAKIIEMLTIQERSLATVRSELPRVIYRTHTIRCPWSAKGALMRYLVETHPAQNLELIDGVKIRQPFDDSWLLVLPDAS
EPLVHLYANSHERDWVDETVRDYRSRVQSFVERQQEYHPAEV

Specific function: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate [H]

COG id: COG1109

COG function: function code G; Phosphomannomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family [H]

Homologues:

Organism=Homo sapiens, GI11761621, Length=372, Percent_Identity=31.7204301075269, Blast_Score=172, Evalue=9e-43,
Organism=Homo sapiens, GI11761619, Length=338, Percent_Identity=32.2485207100592, Blast_Score=165, Evalue=2e-40,
Organism=Homo sapiens, GI31881779, Length=369, Percent_Identity=25.4742547425474, Blast_Score=115, Evalue=2e-25,
Organism=Homo sapiens, GI45447090, Length=369, Percent_Identity=25.4742547425474, Blast_Score=115, Evalue=2e-25,
Organism=Escherichia coli, GI1789837, Length=377, Percent_Identity=25.1989389920424, Blast_Score=79, Evalue=9e-16,
Organism=Escherichia coli, GI1790224, Length=195, Percent_Identity=31.7948717948718, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1788351, Length=185, Percent_Identity=28.1081081081081, Blast_Score=65, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI133931050, Length=373, Percent_Identity=30.8310991957105, Blast_Score=155, Evalue=6e-38,
Organism=Caenorhabditis elegans, GI17509979, Length=370, Percent_Identity=30, Blast_Score=107, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17509981, Length=369, Percent_Identity=29.2682926829268, Blast_Score=100, Evalue=5e-21,
Organism=Saccharomyces cerevisiae, GI6320148, Length=373, Percent_Identity=31.6353887399464, Blast_Score=171, Evalue=4e-43,
Organism=Drosophila melanogaster, GI21355443, Length=374, Percent_Identity=32.620320855615, Blast_Score=175, Evalue=2e-43,
Organism=Drosophila melanogaster, GI24644084, Length=374, Percent_Identity=32.620320855615, Blast_Score=175, Evalue=2e-43,
Organism=Drosophila melanogaster, GI24653912, Length=383, Percent_Identity=23.4986945169713, Blast_Score=87, Evalue=5e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005841 [H]

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV [H]

EC number: =5.4.2.10 [H]

Molecular weight: Translated: 92694; Mature: 92694

Theoretical pI: Translated: 5.91; Mature: 5.91

Prosite motif: PS00101 HEXAPEP_TRANSFERASES ; PS00290 IG_MHC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAVLMAGGSGTRLRPLTCDLPKPMVPILNRPIAEHIINLLKRHHITEVIATLHYLPDVL
CCEEEEECCCCCEEEEEECCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RDYFQDGGDFGVQMTYAVEEDQPLGTAGCVKNIAELLDETFLVISGDSITDFDLGEAIAF
HHHHHCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHCCEEEEEECCCCCCCCCHHHHHH
HKQKQSKATLILTRVPNPIEFGVVITDEAGKIKRFLEKPSTSEIFSDTVNTGTYILEPEV
HHHCCCCEEEEEEECCCCEEEEEEEECCCHHHHHHHHCCCCHHHHHHHCCCCEEEECCHH
LEYLPSNTECDFSKDLFPLLLAKDEPMYGYVAEGYWCDVGHLDAYREAQYDGLDRKVKLD
HHHCCCCCCCCCCCCCHHHEEECCCCCEEEEECCEEECCCCCHHHHHHHCCCCCCEEEEE
FAYRENSPGLWIGQNTYIDPSAHIEAPAVIGNNCRIGARVQIEAGTVIGDNVTIGADANL
EEEECCCCCEEECCCCEECCCCCCCCCEEECCCCEECEEEEEEECEEECCCEEECCCCCC
KRPIVWNGAIIGEEAQLSACVISRGTRVDRRAHVLEASVVGSLSTVGEEAQISPGVRVWP
CCCEEECCEEECCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCEECC
SKKIESGAILNINLIWGNTAQRNLFGQRGVQGLANIDISPEFAVKLGAAYGSTLKPGAKV
CCCCCCCCEEEEEEEECCCHHHHHHHHHCCCHHHCCCCCCHHHEEEECCCCCCCCCCCEE
TVSRDQRNVSRMVTRSLIAGLMSVGVDIQNLDATAIPIARTVIPTMGVAGGIHVRVHPDR
EEECCHHHHHHHHHHHHHHHHHHHCCEEECCCCCHHHHHHHHHHHCCCCCCEEEEECCCC
ADYILIEFMDHKGINISKAQEKKIEGAYFKEDMRRALTHEIGDVAYPSQVIDLYCTAFEK
CCEEEEEEECCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
LLNVSTLNNSRAKVVIDYVYAVSGAVLPQMLDKFGADAVVLNASLNKNAVTTTDRETLLT
HHHHHCCCCCCCEEEEEEHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCEECCHHHHHHH
QLGHVVEALKANFGVQVSANGEQLILVDESGYPIRGELLTALMVDMILTSNPRGTVVVPV
HHHHHHHHHHHCCCEEEECCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEE
HASSAVEQVARRHDGRIIRTKANATALMEACQKNPNVVLGGSGETGFIFPQLHPGFDSMF
CCHHHHHHHHHHCCCEEEEEECCHHHHHHHHHCCCCEEEECCCCCCEEECCCCCCHHHHH
CIAKIIEMLTIQERSLATVRSELPRVIYRTHTIRCPWSAKGALMRYLVETHPAQNLELID
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHCCCCCCCCCC
GVKIRQPFDDSWLLVLPDASEPLVHLYANSHERDWVDETVRDYRSRVQSFVERQQEYHPA
CEEECCCCCCCCEEEECCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
EV
CC
>Mature Secondary Structure
MRAVLMAGGSGTRLRPLTCDLPKPMVPILNRPIAEHIINLLKRHHITEVIATLHYLPDVL
CCEEEEECCCCCEEEEEECCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RDYFQDGGDFGVQMTYAVEEDQPLGTAGCVKNIAELLDETFLVISGDSITDFDLGEAIAF
HHHHHCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHCCEEEEEECCCCCCCCCHHHHHH
HKQKQSKATLILTRVPNPIEFGVVITDEAGKIKRFLEKPSTSEIFSDTVNTGTYILEPEV
HHHCCCCEEEEEEECCCCEEEEEEEECCCHHHHHHHHCCCCHHHHHHHCCCCEEEECCHH
LEYLPSNTECDFSKDLFPLLLAKDEPMYGYVAEGYWCDVGHLDAYREAQYDGLDRKVKLD
HHHCCCCCCCCCCCCCHHHEEECCCCCEEEEECCEEECCCCCHHHHHHHCCCCCCEEEEE
FAYRENSPGLWIGQNTYIDPSAHIEAPAVIGNNCRIGARVQIEAGTVIGDNVTIGADANL
EEEECCCCCEEECCCCEECCCCCCCCCEEECCCCEECEEEEEEECEEECCCEEECCCCCC
KRPIVWNGAIIGEEAQLSACVISRGTRVDRRAHVLEASVVGSLSTVGEEAQISPGVRVWP
CCCEEECCEEECCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCEECC
SKKIESGAILNINLIWGNTAQRNLFGQRGVQGLANIDISPEFAVKLGAAYGSTLKPGAKV
CCCCCCCCEEEEEEEECCCHHHHHHHHHCCCHHHCCCCCCHHHEEEECCCCCCCCCCCEE
TVSRDQRNVSRMVTRSLIAGLMSVGVDIQNLDATAIPIARTVIPTMGVAGGIHVRVHPDR
EEECCHHHHHHHHHHHHHHHHHHHCCEEECCCCCHHHHHHHHHHHCCCCCCEEEEECCCC
ADYILIEFMDHKGINISKAQEKKIEGAYFKEDMRRALTHEIGDVAYPSQVIDLYCTAFEK
CCEEEEEEECCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
LLNVSTLNNSRAKVVIDYVYAVSGAVLPQMLDKFGADAVVLNASLNKNAVTTTDRETLLT
HHHHHCCCCCCCEEEEEEHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCEECCHHHHHHH
QLGHVVEALKANFGVQVSANGEQLILVDESGYPIRGELLTALMVDMILTSNPRGTVVVPV
HHHHHHHHHHHCCCEEEECCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEE
HASSAVEQVARRHDGRIIRTKANATALMEACQKNPNVVLGGSGETGFIFPQLHPGFDSMF
CCHHHHHHHHHHCCCEEEEEECCHHHHHHHHHCCCCEEEECCCCCCEEECCCCCCHHHHH
CIAKIIEMLTIQERSLATVRSELPRVIYRTHTIRCPWSAKGALMRYLVETHPAQNLELID
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHCCCCCCCCCC
GVKIRQPFDDSWLLVLPDASEPLVHLYANSHERDWVDETVRDYRSRVQSFVERQQEYHPA
CEEECCCCCCCCEEEECCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
EV
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA