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The map label for this gene is yciR [C]

Identifier: 17229798

GI number: 17229798

Start: 2777197

End: 2779032

Strand: Direct

Name: yciR [C]

Synonym: alr2306

Alternate gene names: 17229798

Gene position: 2777197-2779032 (Clockwise)

Preceding gene: 17229797

Following gene: 17229799

Centisome position: 43.3

GC content: 35.78

Gene sequence:

>1836_bases
ATGAATCATAAACAGTTAGACCCATATAAAAGCGATATTTTGATTATTGATGATATGGCAGACAATCTGCGTGTCTTGTC
ATCAATTCTTGCTAGGGAAGGATATAACGTTCGTAAAGCTTTAAATTGGCAAATGGCTTGCACCGCTTGTCAAACATTAT
TACCTGATTTGATTTTGCTTGATATTATGATGCCAGAGGTAGATGGTTATGAAGTTTGTCAAAGATTTAAAGCTTGGGAA
CTGACATCTGATATTCCAGTAATTTTTATTAGTGCTTTAGATGATGTTTTTGACAAAGTTAAGGCTTTTAAAGTTGGTGG
GGTAGATTATATTACTAAACCTTTTGAATTAGGAGAGGTCTTAGTACGTGTAAAAAATCAAATAGAATTGCGAACAGCGA
GAATAGAAATATTAACACTTAATGCTGAGTTAGAACAAAGAGTAAAGCAGCGTACTTGGGAGTTAGAAAAGGCTTTGCAA
AAACTCCAAATAGAAGTTAGTGCGCGTCAAAAGTTACAAGGCAAATTGCTTGATATGGCGCTGCATGATGCTCTGACTGG
TTTACCAAACAGAATTTTGTTTATCAGGAGATTAGGAAAAGCTTTAAATCGCGCTAAAGAAGAATCTAATTATCAATTTG
CAGTACTATTTTTAGACTGCGATCGCTTCAAGGTTGTCAATGATTCTTTAGGGCATTTAGTAGGAGATGAATTACTTATT
TCTATCGCTCATCGTCTCCAATCTTGTCTCACACCAGACGCTACTCTAGCAAGACTAGGCGGTGATGAATTTGGCATTTT
GTTAGAGGATATAAAAGATATCCGCATGGCAATTCAAATAGCCGATTACATTCTTCAACAACTATCAATGTCTTTTAAAC
TGTCTAGATACGAAGTTTTTATGAATGTCAGCATTGGCATTAATTGGGGTCATAAAGGATATGATCAACCAGAGTATCTG
CTGCGAGATGCTGATACAGCGATGTATCGTGCTAAAGATTCAGGAAGGTCTAGATATCATGTTTTTGACCCAGCAATGCA
CGAGGAAGTGATCAAAGCCTTAGAAAAGGAAAATGACTTACGTAGGTCAGTGGAAAAACAGGAATTTGTTATTTATTACC
AGCCAATTATTTCTTTGTCTACAGGTAAAATCTCCGGATTTGAAGCACTTGTTCGTTGGCAGCATCCAACTCACGGTTTG
ATTGCTCCGACAGAATTTATCCCTGTAGCGGAAGAAACTGGTCTAATTAATACTATCAATATATGGGTATTACAGTCAGC
TTGTCAGCAACTACGCATCTGGCAATCTCATCCAGGAACTCCTAATAATCTAACCATTAGTGTAAATTTAAGTGCTAAAT
TATTTTTGCAGACTAATTTCCTAACACAAGTCGATCAAATTATCAAAGAGACTCAAATAGATCCATCTAGTTTAGAGCTA
GAAATCACAGAAACTGTCATTATGGAAAATAATAATGAAATTAAAGTAATTCTCCAACAATTAAAGGAGCGTAAAATTAA
ACTAATAATGGATGACTTTGGTACAGGTTATTCGTCCCTGAGCTATTTACATATATTTCCTTTTAATGCACTAAAAATTG
ATAAATCATTTGTTAATCGGATGTTGGATAATCAGGAAAATATGGGATTAGTACCTGCGATGATTAGCATTGCTGCATCT
ATGGGTATGTCGGCGATCGCAGAAGGAGTTGAAACCCAAGAACAATTGGAACAACTGAAAAGTTTAAAATGTGATTTTGC
ACAAGGATATCTATTTTCTCAACCTATAGAGCAGAACTTGGTAATAGATTTTATCGCCTCAGCTACCCAATGGTAG

Upstream 100 bases:

>100_bases
AACAGTTACTCCAGAAAAATCAACTTTATCATTTTCTGAAGTATCTAGTAAATAACTATCAAGTTGAAAAAACTATGGCA
CTAACTAAAACAAATATAGA

Downstream 100 bases:

>100_bases
TTTAGGTTGATACTCCTGAATTTATAATTTCTCAATTCATATCTGTATAGCTTTATTTTTTAGTAATTATTTGATATTAG
TGTCAACAAAATATTTGTTG

Product: two-component response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 611; Mature: 611

Protein sequence:

>611_residues
MNHKQLDPYKSDILIIDDMADNLRVLSSILAREGYNVRKALNWQMACTACQTLLPDLILLDIMMPEVDGYEVCQRFKAWE
LTSDIPVIFISALDDVFDKVKAFKVGGVDYITKPFELGEVLVRVKNQIELRTARIEILTLNAELEQRVKQRTWELEKALQ
KLQIEVSARQKLQGKLLDMALHDALTGLPNRILFIRRLGKALNRAKEESNYQFAVLFLDCDRFKVVNDSLGHLVGDELLI
SIAHRLQSCLTPDATLARLGGDEFGILLEDIKDIRMAIQIADYILQQLSMSFKLSRYEVFMNVSIGINWGHKGYDQPEYL
LRDADTAMYRAKDSGRSRYHVFDPAMHEEVIKALEKENDLRRSVEKQEFVIYYQPIISLSTGKISGFEALVRWQHPTHGL
IAPTEFIPVAEETGLINTINIWVLQSACQQLRIWQSHPGTPNNLTISVNLSAKLFLQTNFLTQVDQIIKETQIDPSSLEL
EITETVIMENNNEIKVILQQLKERKIKLIMDDFGTGYSSLSYLHIFPFNALKIDKSFVNRMLDNQENMGLVPAMISIAAS
MGMSAIAEGVETQEQLEQLKSLKCDFAQGYLFSQPIEQNLVIDFIASATQW

Sequences:

>Translated_611_residues
MNHKQLDPYKSDILIIDDMADNLRVLSSILAREGYNVRKALNWQMACTACQTLLPDLILLDIMMPEVDGYEVCQRFKAWE
LTSDIPVIFISALDDVFDKVKAFKVGGVDYITKPFELGEVLVRVKNQIELRTARIEILTLNAELEQRVKQRTWELEKALQ
KLQIEVSARQKLQGKLLDMALHDALTGLPNRILFIRRLGKALNRAKEESNYQFAVLFLDCDRFKVVNDSLGHLVGDELLI
SIAHRLQSCLTPDATLARLGGDEFGILLEDIKDIRMAIQIADYILQQLSMSFKLSRYEVFMNVSIGINWGHKGYDQPEYL
LRDADTAMYRAKDSGRSRYHVFDPAMHEEVIKALEKENDLRRSVEKQEFVIYYQPIISLSTGKISGFEALVRWQHPTHGL
IAPTEFIPVAEETGLINTINIWVLQSACQQLRIWQSHPGTPNNLTISVNLSAKLFLQTNFLTQVDQIIKETQIDPSSLEL
EITETVIMENNNEIKVILQQLKERKIKLIMDDFGTGYSSLSYLHIFPFNALKIDKSFVNRMLDNQENMGLVPAMISIAAS
MGMSAIAEGVETQEQLEQLKSLKCDFAQGYLFSQPIEQNLVIDFIASATQW
>Mature_611_residues
MNHKQLDPYKSDILIIDDMADNLRVLSSILAREGYNVRKALNWQMACTACQTLLPDLILLDIMMPEVDGYEVCQRFKAWE
LTSDIPVIFISALDDVFDKVKAFKVGGVDYITKPFELGEVLVRVKNQIELRTARIEILTLNAELEQRVKQRTWELEKALQ
KLQIEVSARQKLQGKLLDMALHDALTGLPNRILFIRRLGKALNRAKEESNYQFAVLFLDCDRFKVVNDSLGHLVGDELLI
SIAHRLQSCLTPDATLARLGGDEFGILLEDIKDIRMAIQIADYILQQLSMSFKLSRYEVFMNVSIGINWGHKGYDQPEYL
LRDADTAMYRAKDSGRSRYHVFDPAMHEEVIKALEKENDLRRSVEKQEFVIYYQPIISLSTGKISGFEALVRWQHPTHGL
IAPTEFIPVAEETGLINTINIWVLQSACQQLRIWQSHPGTPNNLTISVNLSAKLFLQTNFLTQVDQIIKETQIDPSSLEL
EITETVIMENNNEIKVILQQLKERKIKLIMDDFGTGYSSLSYLHIFPFNALKIDKSFVNRMLDNQENMGLVPAMISIAAS
MGMSAIAEGVETQEQLEQLKSLKCDFAQGYLFSQPIEQNLVIDFIASATQW

Specific function: Unknown

COG id: COG3706

COG function: function code T; Response regulator containing a CheY-like receiver domain and a GGDEF domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 MHYT domain [H]

Homologues:

Organism=Escherichia coli, GI1787541, Length=432, Percent_Identity=35.8796296296296, Blast_Score=282, Evalue=4e-77,
Organism=Escherichia coli, GI87081921, Length=428, Percent_Identity=36.214953271028, Blast_Score=251, Evalue=7e-68,
Organism=Escherichia coli, GI226510982, Length=420, Percent_Identity=28.8095238095238, Blast_Score=194, Evalue=1e-50,
Organism=Escherichia coli, GI1786507, Length=240, Percent_Identity=35.8333333333333, Blast_Score=155, Evalue=5e-39,
Organism=Escherichia coli, GI87081845, Length=245, Percent_Identity=33.8775510204082, Blast_Score=148, Evalue=9e-37,
Organism=Escherichia coli, GI87081743, Length=252, Percent_Identity=33.3333333333333, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI1790496, Length=252, Percent_Identity=31.3492063492063, Blast_Score=147, Evalue=2e-36,
Organism=Escherichia coli, GI1787055, Length=270, Percent_Identity=29.2592592592593, Blast_Score=137, Evalue=2e-33,
Organism=Escherichia coli, GI1788849, Length=424, Percent_Identity=26.1792452830189, Blast_Score=128, Evalue=8e-31,
Organism=Escherichia coli, GI87081980, Length=235, Percent_Identity=30.2127659574468, Blast_Score=115, Evalue=1e-26,
Organism=Escherichia coli, GI1788502, Length=247, Percent_Identity=26.7206477732794, Blast_Score=114, Evalue=2e-26,
Organism=Escherichia coli, GI87082096, Length=422, Percent_Identity=24.6445497630332, Blast_Score=112, Evalue=1e-25,
Organism=Escherichia coli, GI1788381, Length=441, Percent_Identity=25.3968253968254, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1788956, Length=164, Percent_Identity=37.1951219512195, Blast_Score=91, Evalue=3e-19,
Organism=Escherichia coli, GI87081881, Length=179, Percent_Identity=35.195530726257, Blast_Score=89, Evalue=6e-19,
Organism=Escherichia coli, GI1787262, Length=207, Percent_Identity=30.4347826086957, Blast_Score=86, Evalue=1e-17,
Organism=Escherichia coli, GI1788550, Length=132, Percent_Identity=34.0909090909091, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI87081977, Length=178, Percent_Identity=31.4606741573034, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1788085, Length=163, Percent_Identity=31.9018404907975, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI1787802, Length=146, Percent_Identity=30.1369863013699, Blast_Score=77, Evalue=4e-15,
Organism=Escherichia coli, GI1787816, Length=160, Percent_Identity=32.5, Blast_Score=76, Evalue=6e-15,
Organism=Escherichia coli, GI1786911, Length=123, Percent_Identity=33.3333333333333, Blast_Score=76, Evalue=7e-15,
Organism=Escherichia coli, GI1786599, Length=113, Percent_Identity=33.6283185840708, Blast_Score=75, Evalue=9e-15,
Organism=Escherichia coli, GI1786584, Length=167, Percent_Identity=28.7425149700599, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI87082007, Length=183, Percent_Identity=30.6010928961749, Blast_Score=69, Evalue=8e-13,
Organism=Escherichia coli, GI1790437, Length=106, Percent_Identity=34.9056603773585, Blast_Score=67, Evalue=5e-12,
Organism=Escherichia coli, GI145693134, Length=172, Percent_Identity=31.3953488372093, Blast_Score=66, Evalue=6e-12,
Organism=Escherichia coli, GI1789809, Length=113, Percent_Identity=29.2035398230088, Blast_Score=65, Evalue=9e-12,
Organism=Escherichia coli, GI1788394, Length=72, Percent_Identity=40.2777777777778, Blast_Score=65, Evalue=2e-11,
Organism=Escherichia coli, GI1789650, Length=489, Percent_Identity=20.040899795501, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1786784, Length=123, Percent_Identity=30.0813008130081, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1790860, Length=117, Percent_Identity=26.4957264957265, Blast_Score=62, Evalue=8e-11,
Organism=Escherichia coli, GI1787229, Length=114, Percent_Identity=33.3333333333333, Blast_Score=62, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR005330 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF03707 MHYT [H]

EC number: NA

Molecular weight: Translated: 69696; Mature: 69696

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50883 EAL ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNHKQLDPYKSDILIIDDMADNLRVLSSILAREGYNVRKALNWQMACTACQTLLPDLILL
CCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
DIMMPEVDGYEVCQRFKAWELTSDIPVIFISALDDVFDKVKAFKVGGVDYITKPFELGEV
HHHCCCCCHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHEECCCHHHHCCCHHHHHH
LVRVKNQIELRTARIEILTLNAELEQRVKQRTWELEKALQKLQIEVSARQKLQGKLLDMA
HHHHHHHHEEEEEEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LHDALTGLPNRILFIRRLGKALNRAKEESNYQFAVLFLDCDRFKVVNDSLGHLVGDELLI
HHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCEEEHHHHHHHHHHHHHHH
SIAHRLQSCLTPDATLARLGGDEFGILLEDIKDIRMAIQIADYILQQLSMSFKLSRYEVF
HHHHHHHHHCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEE
MNVSIGINWGHKGYDQPEYLLRDADTAMYRAKDSGRSRYHVFDPAMHEEVIKALEKENDL
EEEEEEEECCCCCCCCHHHHHHCCCHHHHEECCCCCCEEEEECHHHHHHHHHHHHCCHHH
RRSVEKQEFVIYYQPIISLSTGKISGFEALVRWQHPTHGLIAPTEFIPVAEETGLINTIN
HHHHCCCCEEEEEECEEEECCCCCCCHHHHHEECCCCCCCCCCCCCCCCCCCCCCEEHHH
IWVLQSACQQLRIWQSHPGTPNNLTISVNLSAKLFLQTNFLTQVDQIIKETQIDPSSLEL
HHHHHHHHHHHHHHHCCCCCCCEEEEEEEEEEEEEEEHHHHHHHHHHHHHHCCCCCCEEE
EITETVIMENNNEIKVILQQLKERKIKLIMDDFGTGYSSLSYLHIFPFNALKIDKSFVNR
EEEEEEEEECCCHHHHHHHHHHHHHHEEEEHHCCCCCCCCCEEEEECCCCEEECHHHHHH
MLDNQENMGLVPAMISIAASMGMSAIAEGVETQEQLEQLKSLKCDFAQGYLFSQPIEQNL
HHCCCCCCCHHHHHHHHHHHHCHHHHHHCCCHHHHHHHHHHCCCCHHCCCCCCCCCCCHH
VIDFIASATQW
HHHHHHHCCCC
>Mature Secondary Structure
MNHKQLDPYKSDILIIDDMADNLRVLSSILAREGYNVRKALNWQMACTACQTLLPDLILL
CCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
DIMMPEVDGYEVCQRFKAWELTSDIPVIFISALDDVFDKVKAFKVGGVDYITKPFELGEV
HHHCCCCCHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHEECCCHHHHCCCHHHHHH
LVRVKNQIELRTARIEILTLNAELEQRVKQRTWELEKALQKLQIEVSARQKLQGKLLDMA
HHHHHHHHEEEEEEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LHDALTGLPNRILFIRRLGKALNRAKEESNYQFAVLFLDCDRFKVVNDSLGHLVGDELLI
HHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCEEEHHHHHHHHHHHHHHH
SIAHRLQSCLTPDATLARLGGDEFGILLEDIKDIRMAIQIADYILQQLSMSFKLSRYEVF
HHHHHHHHHCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEE
MNVSIGINWGHKGYDQPEYLLRDADTAMYRAKDSGRSRYHVFDPAMHEEVIKALEKENDL
EEEEEEEECCCCCCCCHHHHHHCCCHHHHEECCCCCCEEEEECHHHHHHHHHHHHCCHHH
RRSVEKQEFVIYYQPIISLSTGKISGFEALVRWQHPTHGLIAPTEFIPVAEETGLINTIN
HHHHCCCCEEEEEECEEEECCCCCCCHHHHHEECCCCCCCCCCCCCCCCCCCCCCEEHHH
IWVLQSACQQLRIWQSHPGTPNNLTISVNLSAKLFLQTNFLTQVDQIIKETQIDPSSLEL
HHHHHHHHHHHHHHHCCCCCCCEEEEEEEEEEEEEEEHHHHHHHHHHHHHHCCCCCCEEE
EITETVIMENNNEIKVILQQLKERKIKLIMDDFGTGYSSLSYLHIFPFNALKIDKSFVNR
EEEEEEEEECCCHHHHHHHHHHHHHHEEEEHHCCCCCCCCCEEEEECCCCEEECHHHHHH
MLDNQENMGLVPAMISIAASMGMSAIAEGVETQEQLEQLKSLKCDFAQGYLFSQPIEQNL
HHCCCCCCCHHHHHHHHHHHHCHHHHHHCCCHHHHHHHHHHCCCCHHCCCCCCCCCCCHH
VIDFIASATQW
HHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]