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The map label for this gene is nhaA2 [H]

Identifier: 17229632

GI number: 17229632

Start: 2569107

End: 2569664

Strand: Direct

Name: nhaA2 [H]

Synonym: alr2140

Alternate gene names: 17229632

Gene position: 2569107-2569664 (Clockwise)

Preceding gene: 17229631

Following gene: 17229633

Centisome position: 40.06

GC content: 43.91

Gene sequence:

>558_bases
ATGAACGATGATCGCAGCTACAGTTCCTTACTTGTACCCCCTTCAACTCAAGATTGGATGCAAGGTGTGCTGAGTGCCAA
GGTCGTGCTGGTGATGTATGGAGACTATCAATGCTCTAGAAGTGCGGACGTTTACAGGATGATTCAAGGAATCAAACAAG
AGCTGAGTGCTTCTTTTGGAGAAGATTATTTATGCTTTATCTTCCGTCATTTTCCGCAAACACAGATTCATCCTCATGCT
CAACGAGCCGCCGAAGTCGCTGAAGCCGCCGCTGCCCAAGGACAGTTTTGGCCAATGCACGATACTTTATTTGTTTATCA
ACAGAAGTTAGAGAACGGTTATCTTGTAGAGTACGCCAATGATTTGGGGCTTGATATTCCTCAGTTTCTCAAAAACTTGT
CTAAACAAGTATATGTCGATCGCATCCACGAAGATATCGAAAGTGGAATACACAGTGGAGTAACAACTGCCCCAGTCCTA
TTTATCAATACCATTCGATATACCGCACGCTGGAAAATGACAGAGTTGATGACAGCCATTGTTGCAGCAAGTCACTAA

Upstream 100 bases:

>100_bases
TGAAGGCAATTTCCTATATTGAATGTATGCAAATAGAGATGCAGTCAATGGATTGAGCAAGTCAATTGCAAAGTTCCATA
CTTACTGCAAACGTAAAAAA

Downstream 100 bases:

>100_bases
GCTCTATTTATATCTGACTTGTTTGTGAGTGCTAGTCGGCGATCGCGCATTTGCTCGCTAGTTTTTGCCTGTTTTGTTGA
ATTTAAACGCCTCACTGGAA

Product: hypothetical protein

Products: NA

Alternate protein names: Sodium/proton antiporter nhaA 2 [H]

Number of amino acids: Translated: 185; Mature: 185

Protein sequence:

>185_residues
MNDDRSYSSLLVPPSTQDWMQGVLSAKVVLVMYGDYQCSRSADVYRMIQGIKQELSASFGEDYLCFIFRHFPQTQIHPHA
QRAAEVAEAAAAQGQFWPMHDTLFVYQQKLENGYLVEYANDLGLDIPQFLKNLSKQVYVDRIHEDIESGIHSGVTTAPVL
FINTIRYTARWKMTELMTAIVAASH

Sequences:

>Translated_185_residues
MNDDRSYSSLLVPPSTQDWMQGVLSAKVVLVMYGDYQCSRSADVYRMIQGIKQELSASFGEDYLCFIFRHFPQTQIHPHA
QRAAEVAEAAAAQGQFWPMHDTLFVYQQKLENGYLVEYANDLGLDIPQFLKNLSKQVYVDRIHEDIESGIHSGVTTAPVL
FINTIRYTARWKMTELMTAIVAASH
>Mature_185_residues
MNDDRSYSSLLVPPSTQDWMQGVLSAKVVLVMYGDYQCSRSADVYRMIQGIKQELSASFGEDYLCFIFRHFPQTQIHPHA
QRAAEVAEAAAAQGQFWPMHDTLFVYQQKLENGYLVEYANDLGLDIPQFLKNLSKQVYVDRIHEDIESGIHSGVTTAPVL
FINTIRYTARWKMTELMTAIVAASH

Specific function: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons [H]

COG id: COG1651

COG function: function code O; Protein-disulfide isomerase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001853
- InterPro:   IPR023171
- InterPro:   IPR004670
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF01323 DSBA; PF06965 Na_H_antiport_1 [H]

EC number: NA

Molecular weight: Translated: 21055; Mature: 21055

Theoretical pI: Translated: 5.85; Mature: 5.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDDRSYSSLLVPPSTQDWMQGVLSAKVVLVMYGDYQCSRSADVYRMIQGIKQELSASFG
CCCCCCCCEEECCCCCHHHHHHHHHHHEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCC
EDYLCFIFRHFPQTQIHPHAQRAAEVAEAAAAQGQFWPMHDTLFVYQQKLENGYLVEYAN
CHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCEEEEECC
DLGLDIPQFLKNLSKQVYVDRIHEDIESGIHSGVTTAPVLFINTIRYTARWKMTELMTAI
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
VAASH
HHCCC
>Mature Secondary Structure
MNDDRSYSSLLVPPSTQDWMQGVLSAKVVLVMYGDYQCSRSADVYRMIQGIKQELSASFG
CCCCCCCCEEECCCCCHHHHHHHHHHHEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCC
EDYLCFIFRHFPQTQIHPHAQRAAEVAEAAAAQGQFWPMHDTLFVYQQKLENGYLVEYAN
CHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCEEEEECC
DLGLDIPQFLKNLSKQVYVDRIHEDIESGIHSGVTTAPVLFINTIRYTARWKMTELMTAI
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
VAASH
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA