Click here to switch to the map view.

The map label for this gene is arnT [H]

Identifier: 17229568

GI number: 17229568

Start: 2483211

End: 2484830

Strand: Direct

Name: arnT [H]

Synonym: alr2076

Alternate gene names: 17229568

Gene position: 2483211-2484830 (Clockwise)

Preceding gene: 17229567

Following gene: 17229571

Centisome position: 38.72

GC content: 42.72

Gene sequence:

>1620_bases
ATGCAGGAAGGAAGCTTTATTTGGGGTCATCTGGAAAGACAGCACCGCGCAGTTGATAAATGGATTGATCGCTTATGGCT
AGTAGTGTTGTTAATTGCAGCATTACTATTATTTAGCGTTAACTTGGGAGGATTACCCCTGCAAGATTGGGATGAGGGAA
CTATAGCCCAAATCGCTAGGGAAATAACACAAGAATCGGCCAATTCCCTACGTTGGCTATATCCCACCCTAAGAGGGCAA
CCTTATCACGATACACCGCCTCTCATGCACATACTGATTGCAGGGGCTTACTATTTAGGAGGTGTGAATGAATGGACAAC
ACGTTTACCAGGAGCAATTTTAACCGCCTTATCAGTACCATTACTATACTGTCTTGGTAGAGAGATATTCCGTCAACGCT
GGGCAGCGATTTATAGTGCCTTAATCTACTTAACCATGCTGCCTGTAGTCCGTTATGGGCGCTTGGCGATGTTAGAAGGG
GCGGTGGTGAGTTTCTTGTTGGTGATGATGCTGTGTGTATTGCGATCGCGTCGAGATTTACGCTACTGTCTCGGCATAGG
TTTAAGTTTAGGATTAATTTGTCTGACTCAAGGACTGTCAGGTTTTTTATTAGGTGCAGTCGTCTTAGTATTTTTGTTTT
GGGATACACCAAGGCTACTTACCAGTTATTATCTATGGATAGCGATCGCCATTGGGATTTTGCCTGTAGCTGCTTGGTAT
GGCGCTCAAATAGTACAATATGGCAATGATTTTGTCCAGAATGGCTTGCTTCTTCAATCCCTACAACAAACGGGTATAGT
TAATCACAAGAATGCTCAACCATCTTGGTTTTACATGGTTGAACTCCTTAAATGGACTTGGCCTTGGTTAATCTTCTTAC
CACAAACGACAAAGTTACTTTGGGAAAATCGCAATCTTAGCTGGGCAAGACTCATACTTGTATGGAGCATAGTTTATTTA
CTACTCATTTCTCTCATGAGTGTGAAGCTTGCTTGGTATATATTCCCCATTTACCCCAGCCTAGCCTTAGCTTTTGGCGC
ACAGTTAGCAGAAATAGAAAACTTACCTTTACTCTCATCCTATCCCCGCACTTGGGTCGCTGGTTTGTCAATCTTAGCCG
TAGTAGCTTCAGCTGCTAGCATTCACTTTAGTTGGGGTATCGCTGCCAAAACTGACCTACAGCTAATTTTTGCCGCAGTC
GCTTTGACAATGATTATGGGAGCTATTTTAGCAGAACGAGGCGACGGACAATTTCTCAAAATATTGTTTTGGGGTAGTTA
TATTTCCCTGCTGCTGTTGATGAAATCTAACTACTGGGTTTGGGAATTATGGCAAGCTTACCCTGTAAAACCTGTAGCGG
CCATGATAGAGAAAGCAAATCCAGCTGCAAAGAAGATTTATACATCTTTTCCTTATCATCGCCCATCATTGGATTTTTAT
AGCGATCGCCATATTATTCCCGCCTCTGTCGAAGAACTAAAACATCATTGGCACTACGACAGACAACCGTATCTACTCAT
CAGTTCATCAGATTCCCAACGTCTGCAATTAGACTCTGTTCAGCTACTAGACAAAACTGAAGGTTGGCAACTAGTAACCA
AAGAAACTAATCGGTTGTAA

Upstream 100 bases:

>100_bases
AGTATTTATTCAGTAAACAAGTTGTTACTGGGTGGCACATTAGAGATTCACTTTGATCTCTATGTAATCAAACCAGCAAG
TAAAATGATTATCATAGAAT

Downstream 100 bases:

>100_bases
AAAAGTGCAGAGTGATTTTAGGGTTAGCGGGGCGTTGAGCAACGTACTGAGTTAGGAGAAGGATATCATTAATTCTTATT
TCTCCCTGCTCCCTGCCCCC

Product: hypothetical protein

Products: NA

Alternate protein names: 4-amino-4-deoxy-L-arabinose lipid A transferase; Lipid IV(A) 4-amino-4-deoxy-L-arabinosyltransferase; Undecaprenyl phosphate-alpha-L-Ara4N transferase [H]

Number of amino acids: Translated: 539; Mature: 539

Protein sequence:

>539_residues
MQEGSFIWGHLERQHRAVDKWIDRLWLVVLLIAALLLFSVNLGGLPLQDWDEGTIAQIAREITQESANSLRWLYPTLRGQ
PYHDTPPLMHILIAGAYYLGGVNEWTTRLPGAILTALSVPLLYCLGREIFRQRWAAIYSALIYLTMLPVVRYGRLAMLEG
AVVSFLLVMMLCVLRSRRDLRYCLGIGLSLGLICLTQGLSGFLLGAVVLVFLFWDTPRLLTSYYLWIAIAIGILPVAAWY
GAQIVQYGNDFVQNGLLLQSLQQTGIVNHKNAQPSWFYMVELLKWTWPWLIFLPQTTKLLWENRNLSWARLILVWSIVYL
LLISLMSVKLAWYIFPIYPSLALAFGAQLAEIENLPLLSSYPRTWVAGLSILAVVASAASIHFSWGIAAKTDLQLIFAAV
ALTMIMGAILAERGDGQFLKILFWGSYISLLLLMKSNYWVWELWQAYPVKPVAAMIEKANPAAKKIYTSFPYHRPSLDFY
SDRHIIPASVEELKHHWHYDRQPYLLISSSDSQRLQLDSVQLLDKTEGWQLVTKETNRL

Sequences:

>Translated_539_residues
MQEGSFIWGHLERQHRAVDKWIDRLWLVVLLIAALLLFSVNLGGLPLQDWDEGTIAQIAREITQESANSLRWLYPTLRGQ
PYHDTPPLMHILIAGAYYLGGVNEWTTRLPGAILTALSVPLLYCLGREIFRQRWAAIYSALIYLTMLPVVRYGRLAMLEG
AVVSFLLVMMLCVLRSRRDLRYCLGIGLSLGLICLTQGLSGFLLGAVVLVFLFWDTPRLLTSYYLWIAIAIGILPVAAWY
GAQIVQYGNDFVQNGLLLQSLQQTGIVNHKNAQPSWFYMVELLKWTWPWLIFLPQTTKLLWENRNLSWARLILVWSIVYL
LLISLMSVKLAWYIFPIYPSLALAFGAQLAEIENLPLLSSYPRTWVAGLSILAVVASAASIHFSWGIAAKTDLQLIFAAV
ALTMIMGAILAERGDGQFLKILFWGSYISLLLLMKSNYWVWELWQAYPVKPVAAMIEKANPAAKKIYTSFPYHRPSLDFY
SDRHIIPASVEELKHHWHYDRQPYLLISSSDSQRLQLDSVQLLDKTEGWQLVTKETNRL
>Mature_539_residues
MQEGSFIWGHLERQHRAVDKWIDRLWLVVLLIAALLLFSVNLGGLPLQDWDEGTIAQIAREITQESANSLRWLYPTLRGQ
PYHDTPPLMHILIAGAYYLGGVNEWTTRLPGAILTALSVPLLYCLGREIFRQRWAAIYSALIYLTMLPVVRYGRLAMLEG
AVVSFLLVMMLCVLRSRRDLRYCLGIGLSLGLICLTQGLSGFLLGAVVLVFLFWDTPRLLTSYYLWIAIAIGILPVAAWY
GAQIVQYGNDFVQNGLLLQSLQQTGIVNHKNAQPSWFYMVELLKWTWPWLIFLPQTTKLLWENRNLSWARLILVWSIVYL
LLISLMSVKLAWYIFPIYPSLALAFGAQLAEIENLPLLSSYPRTWVAGLSILAVVASAASIHFSWGIAAKTDLQLIFAAV
ALTMIMGAILAERGDGQFLKILFWGSYISLLLLMKSNYWVWELWQAYPVKPVAAMIEKANPAAKKIYTSFPYHRPSLDFY
SDRHIIPASVEELKHHWHYDRQPYLLISSSDSQRLQLDSVQLLDKTEGWQLVTKETNRL

Specific function: Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides [H]

COG id: COG1807

COG function: function code M; 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 83 family [H]

Homologues:

Organism=Escherichia coli, GI1788591, Length=305, Percent_Identity=26.8852459016393, Blast_Score=80, Evalue=4e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022839
- InterPro:   IPR003342 [H]

Pfam domain/function: PF02366 PMT [H]

EC number: =2.4.2.43 [H]

Molecular weight: Translated: 61503; Mature: 61503

Theoretical pI: Translated: 9.02; Mature: 9.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCCCCCHHHHHHHHHCCCCCCCEEEEECCCCCCEEHHHHHHHHCCCCCEEECCCCCCC
>Mature Secondary Structure
MQEGSFIWGHLERQHRAVDKWIDRLWLVVLLIAALLLFSVNLGGLPLQDWDEGTIAQIAR
CCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHH
EITQESANSLRWLYPTLRGQPYHDTPPLMHILIAGAYYLGGVNEWTTRLPGAILTALSVP
HHHHHHHCCCEEEEHHHCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHCCHHHHHHHHHH
LLYCLGREIFRQRWAAIYSALIYLTMLPVVRYGRLAMLEGAVVSFLLVMMLCVLRSRRDL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCHH
RYCLGIGLSLGLICLTQGLSGFLLGAVVLVFLFWDTPRLLTSYYLWIAIAIGILPVAAWY
HHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
GAQIVQYGNDFVQNGLLLQSLQQTGIVNHKNAQPSWFYMVELLKWTWPWLIFLPQTTKLL
HHHHHHHCHHHHHCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCEEEEECCHHHHH
WENRNLSWARLILVWSIVYLLLISLMSVKLAWYIFPIYPSLALAFGAQLAEIENLPLLSS
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
YPRTWVAGLSILAVVASAASIHFSWGIAAKTDLQLIFAAVALTMIMGAILAERGDGQFLK
CCHHHHHHHHHHHHHHHHHHEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEE
ILFWGSYISLLLLMKSNYWVWELWQAYPVKPVAAMIEKANPAAKKIYTSFPYHRPSLDFY
HHHHHHHHHHHHHHHCCCCEEEHHHHCCCCHHHHHHHCCCHHHHHHHHCCCCCCCCCCCC
SDRHIIPASVEELKHHWHYDRQPYLLISSSDSQRLQLDSVQLLDKTEGWQLVTKETNRL
CCCCCCCHHHHHHHHHCCCCCCCEEEEECCCCCCEEHHHHHHHHCCCCCEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA