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The map label for this gene is grsT [H]

Identifier: 17229537

GI number: 17229537

Start: 2450627

End: 2451388

Strand: Direct

Name: grsT [H]

Synonym: alr2045

Alternate gene names: 17229537

Gene position: 2450627-2451388 (Clockwise)

Preceding gene: 17229536

Following gene: 17229538

Centisome position: 38.21

GC content: 43.18

Gene sequence:

>762_bases
ATGAAGACCAACACATCAAGTTACAACTCTTGGGTAATTTGTCCCAAGCCAAATCCTGTAGCGGCTTTGCGTTTATTTTG
CTTTCCTTATGCGGGTGGTAGTTCTTTTATCTTTCGCACTTGGTCAAATTATCTACCTGCATCTGTAGAGGTGTGTGCTA
TTGAACTTCCTGGGCGAGGAAGACAAATGCAGTTAGCGCCTTTTCACAAGATGGAACCGCTTGTGGATGCGATCGCCTCC
GCTATCTACCCATATTTAGACAAGCCATTCGCCTTCCTGGGACATAGCATGGGTGGCTTGGTCAGCTTTGAAGTGGCGCG
TTTCCTGCACAAACAGTATGATATTCACCCGGTTCACTTGTTTATATCCGGTCGTCGCCCCCCACACATTCCCGATTTAC
ATCCACCTATTCATAATCTACCCGAACCAGCTTTTATAGAAGAACTACGCCATCTCAACGGTACACCATCGACAGTATTA
GAAAATGCAGAACTAATGCAGCTATTTTTGCCGATTTTACGAGCTGATTTTGCAGTTTTAGAAACTTATATTTATACTCC
TGAATTACCTTTAGAATGTCCCCTTACAGTTTTTGGCGGATTACAAGATTCGGAAGTTAGTTGTGATGAGTTGCAAGCAT
GGCGAGAGCAGACAAAGGCTGACTTTAACTTACATATATTCCCCGGCGACCACTTTTTTCTGCACTCGGCTCAATCTCTT
GTACTCGAACAATTGGCTAAATATTTGTCTATGAATGTTTAA

Upstream 100 bases:

>100_bases
GAACGATTAATCATAAATAATTTCTCAGTTTCTATTTGTAGAGAGGTTTAACTTCTCTACAATGGTTTTGTTGAGAAAAA
ATCCCAGATAATTCAATGTA

Downstream 100 bases:

>100_bases
AACCCTTACACCCCTATACACCCCTACACCCCTACACCCCTAAACACCCACACCCAATCTCAACAAAAAATCTGCGTGCA
TAAGTCCTAACTTTAAAAAA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 253; Mature: 253

Protein sequence:

>253_residues
MKTNTSSYNSWVICPKPNPVAALRLFCFPYAGGSSFIFRTWSNYLPASVEVCAIELPGRGRQMQLAPFHKMEPLVDAIAS
AIYPYLDKPFAFLGHSMGGLVSFEVARFLHKQYDIHPVHLFISGRRPPHIPDLHPPIHNLPEPAFIEELRHLNGTPSTVL
ENAELMQLFLPILRADFAVLETYIYTPELPLECPLTVFGGLQDSEVSCDELQAWREQTKADFNLHIFPGDHFFLHSAQSL
VLEQLAKYLSMNV

Sequences:

>Translated_253_residues
MKTNTSSYNSWVICPKPNPVAALRLFCFPYAGGSSFIFRTWSNYLPASVEVCAIELPGRGRQMQLAPFHKMEPLVDAIAS
AIYPYLDKPFAFLGHSMGGLVSFEVARFLHKQYDIHPVHLFISGRRPPHIPDLHPPIHNLPEPAFIEELRHLNGTPSTVL
ENAELMQLFLPILRADFAVLETYIYTPELPLECPLTVFGGLQDSEVSCDELQAWREQTKADFNLHIFPGDHFFLHSAQSL
VLEQLAKYLSMNV
>Mature_253_residues
MKTNTSSYNSWVICPKPNPVAALRLFCFPYAGGSSFIFRTWSNYLPASVEVCAIELPGRGRQMQLAPFHKMEPLVDAIAS
AIYPYLDKPFAFLGHSMGGLVSFEVARFLHKQYDIHPVHLFISGRRPPHIPDLHPPIHNLPEPAFIEELRHLNGTPSTVL
ENAELMQLFLPILRADFAVLETYIYTPELPLECPLTVFGGLQDSEVSCDELQAWREQTKADFNLHIFPGDHFFLHSAQSL
VLEQLAKYLSMNV

Specific function: Probable thioesterase involved in the biosynthesis of gramicidin S [H]

COG id: COG3208

COG function: function code Q; Predicted thioesterase involved in non-ribosomal peptide biosynthesis

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioesterase family [H]

Homologues:

Organism=Homo sapiens, GI89257335, Length=228, Percent_Identity=34.2105263157895, Blast_Score=128, Evalue=5e-30,
Organism=Homo sapiens, GI8922871, Length=281, Percent_Identity=29.1814946619217, Blast_Score=107, Evalue=1e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012223
- InterPro:   IPR001031 [H]

Pfam domain/function: PF00975 Thioesterase [H]

EC number: NA

Molecular weight: Translated: 28620; Mature: 28620

Theoretical pI: Translated: 6.22; Mature: 6.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTNTSSYNSWVICPKPNPVAALRLFCFPYAGGSSFIFRTWSNYLPASVEVCAIELPGRG
CCCCCCCCCEEEEECCCCHHHHHHHHEEECCCCCCEEEECHHHCCCCCEEEEEEECCCCC
RQMQLAPFHKMEPLVDAIASAIYPYLDKPFAFLGHSMGGLVSFEVARFLHKQYDIHPVHL
CEEEECCCHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCHHHHHHHHHHHHHCCCEEEEE
FISGRRPPHIPDLHPPIHNLPEPAFIEELRHLNGTPSTVLENAELMQLFLPILRADFAVL
EEECCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
ETYIYTPELPLECPLTVFGGLQDSEVSCDELQAWREQTKADFNLHIFPGDHFFLHSAQSL
HHHHCCCCCCCCCCHHHHCCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHH
VLEQLAKYLSMNV
HHHHHHHHHCCCC
>Mature Secondary Structure
MKTNTSSYNSWVICPKPNPVAALRLFCFPYAGGSSFIFRTWSNYLPASVEVCAIELPGRG
CCCCCCCCCEEEEECCCCHHHHHHHHEEECCCCCCEEEECHHHCCCCCEEEEEEECCCCC
RQMQLAPFHKMEPLVDAIASAIYPYLDKPFAFLGHSMGGLVSFEVARFLHKQYDIHPVHL
CEEEECCCHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCHHHHHHHHHHHHHCCCEEEEE
FISGRRPPHIPDLHPPIHNLPEPAFIEELRHLNGTPSTVLENAELMQLFLPILRADFAVL
EEECCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
ETYIYTPELPLECPLTVFGGLQDSEVSCDELQAWREQTKADFNLHIFPGDHFFLHSAQSL
HHHHCCCCCCCCCCHHHHCCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHH
VLEQLAKYLSMNV
HHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2477357; 7512553 [H]