BacMap

Definition	Nostoc sp. PCC 7120, complete genome.
Accession	NC_003272
Length	6,413,771

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The map label for this gene is fabG [H]

Identifier: 17229376

GI number: 17229376

Start: 2250052

End: 2250735

Strand: Reverse

Name: fabG [H]

Synonym: all1884

Alternate gene names: 17229376

Gene position: 2250735-2250052 (Counterclockwise)

Preceding gene: 17229378

Following gene: 17229374

Centisome position: 35.09

GC content: 44.3

Gene sequence:

>684_bases
ATGGTCAAACTCATCCTCATTACTGGTGTCAGCCGAGGTCTGGGTTACGCTTTGACAGAGCGGTTTATTCAAGAAGGACA
TACGATTATTGGTTGCGCTCGTTCCCAAGTCACTGTTGAGAAATTAAGCCACAAATTTGGCTCACCCCACAACTTTGTCG
CCGTGGATGTAGCAGATGAGGCACAGGTAAAAGCTTGGGCAGAACTTATACTCAAGGAATACGAACCACCAGACATATTA
ATTAATAATGCAGCAATTGCTAATCAACCAGCACCTTTATGGGAAGTTCCCTCTACGGATTTTTCCCAATTGATTGATAT
CAATATCAAAGGGGTTGTGCATATAATTCGCTACTTTATACCTGCAATGGTACAGAAGCGACACGGCATTATCATTAACT
TGAGTTCCGGCTGGGGACGCTCTACTTCACCCTTAGTTGCTCCCTATTGTGCCTCTAAATGGGCAATTGAAGGGTTAACT
CGTGCTTTGGCGCAAGAACTACCTGCTGGGATGGCGGCTATTCCCCTCAATCCAGGGATTATTCACACGGATATGTTGGA
TATTTGTTTTGGAGAAGAAGCCGTCAATTACCCACCGATTTCTCAATGGGTATTAAAAGCTGTTCCCTTTATTCTCCAGT
TGAAACCCACAGATAACGGTGTACCCTTGACTGTTCCTAGTTGA

Upstream 100 bases:

>100_bases
ATCAGCCAATAGTATGAAATTCATGCGACTTCAGAGAGTTTAATCATTGGCAGTAATAGTATTTTATTGTTGAGCTTGCT
GAGACAATAAAAAGGAAAAT

Downstream 100 bases:

>100_bases
AATTAAGGGTTGGGAGGAGGGGGGTAACGGAAGCAGGGGGAGCAGAGGGAGCAAAGGGGAAGAACTAATGACAACTGACC
TGACTATCGATACAGCCAAA

Product: hypothetical protein

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 227; Mature: 227

Protein sequence:

>227_residues
MVKLILITGVSRGLGYALTERFIQEGHTIIGCARSQVTVEKLSHKFGSPHNFVAVDVADEAQVKAWAELILKEYEPPDIL
INNAAIANQPAPLWEVPSTDFSQLIDINIKGVVHIIRYFIPAMVQKRHGIIINLSSGWGRSTSPLVAPYCASKWAIEGLT
RALAQELPAGMAAIPLNPGIIHTDMLDICFGEEAVNYPPISQWVLKAVPFILQLKPTDNGVPLTVPS

Sequences:

>Translated_227_residues
MVKLILITGVSRGLGYALTERFIQEGHTIIGCARSQVTVEKLSHKFGSPHNFVAVDVADEAQVKAWAELILKEYEPPDIL
INNAAIANQPAPLWEVPSTDFSQLIDINIKGVVHIIRYFIPAMVQKRHGIIINLSSGWGRSTSPLVAPYCASKWAIEGLT
RALAQELPAGMAAIPLNPGIIHTDMLDICFGEEAVNYPPISQWVLKAVPFILQLKPTDNGVPLTVPS
>Mature_227_residues
MVKLILITGVSRGLGYALTERFIQEGHTIIGCARSQVTVEKLSHKFGSPHNFVAVDVADEAQVKAWAELILKEYEPPDIL
INNAAIANQPAPLWEVPSTDFSQLIDINIKGVVHIIRYFIPAMVQKRHGIIINLSSGWGRSTSPLVAPYCASKWAIEGLT
RALAQELPAGMAAIPLNPGIIHTDMLDICFGEEAVNYPPISQWVLKAVPFILQLKPTDNGVPLTVPS

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI20149619, Length=192, Percent_Identity=27.0833333333333, Blast_Score=82, Evalue=4e-16,
Organism=Homo sapiens, GI109715829, Length=193, Percent_Identity=28.4974093264249, Blast_Score=81, Evalue=6e-16,
Organism=Homo sapiens, GI40254992, Length=221, Percent_Identity=27.6018099547511, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI210032110, Length=188, Percent_Identity=27.1276595744681, Blast_Score=77, Evalue=9e-15,
Organism=Homo sapiens, GI22507405, Length=187, Percent_Identity=24.5989304812834, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI7706318, Length=193, Percent_Identity=24.3523316062176, Blast_Score=74, Evalue=8e-14,
Organism=Homo sapiens, GI150247226, Length=184, Percent_Identity=27.1739130434783, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI32483357, Length=185, Percent_Identity=28.6486486486486, Blast_Score=72, Evalue=3e-13,
Organism=Homo sapiens, GI40548397, Length=188, Percent_Identity=27.6595744680851, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI214010158, Length=188, Percent_Identity=27.6595744680851, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI214010156, Length=188, Percent_Identity=27.6595744680851, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI22758144, Length=188, Percent_Identity=27.6595744680851, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI4758504, Length=193, Percent_Identity=28.4974093264249, Blast_Score=71, Evalue=8e-13,
Organism=Homo sapiens, GI7705925, Length=211, Percent_Identity=25.5924170616114, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI15277342, Length=198, Percent_Identity=32.3232323232323, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI40807363, Length=196, Percent_Identity=28.5714285714286, Blast_Score=69, Evalue=2e-12,
Organism=Homo sapiens, GI142976729, Length=195, Percent_Identity=24.6153846153846, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI10190704, Length=168, Percent_Identity=29.1666666666667, Blast_Score=68, Evalue=9e-12,
Organism=Homo sapiens, GI44680136, Length=189, Percent_Identity=25.9259259259259, Blast_Score=66, Evalue=2e-11,
Organism=Homo sapiens, GI44680133, Length=189, Percent_Identity=25.9259259259259, Blast_Score=66, Evalue=2e-11,
Organism=Homo sapiens, GI17738292, Length=189, Percent_Identity=25.9259259259259, Blast_Score=66, Evalue=2e-11,
Organism=Homo sapiens, GI59889578, Length=163, Percent_Identity=27.6073619631902, Blast_Score=66, Evalue=3e-11,
Organism=Escherichia coli, GI1787335, Length=184, Percent_Identity=32.0652173913043, Blast_Score=101, Evalue=4e-23,
Organism=Escherichia coli, GI1787820, Length=179, Percent_Identity=30.1675977653631, Blast_Score=95, Evalue=4e-21,
Organism=Escherichia coli, GI1790717, Length=212, Percent_Identity=29.7169811320755, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI87082100, Length=188, Percent_Identity=32.9787234042553, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI2367175, Length=191, Percent_Identity=30.8900523560209, Blast_Score=71, Evalue=5e-14,
Organism=Escherichia coli, GI1786812, Length=184, Percent_Identity=27.7173913043478, Blast_Score=70, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17508895, Length=193, Percent_Identity=27.4611398963731, Blast_Score=84, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI17560676, Length=205, Percent_Identity=23.9024390243902, Blast_Score=77, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI17561402, Length=199, Percent_Identity=27.1356783919598, Blast_Score=74, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI193210355, Length=188, Percent_Identity=27.1276595744681, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI193204405, Length=208, Percent_Identity=31.7307692307692, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI71994604, Length=187, Percent_Identity=26.2032085561497, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI115534660, Length=189, Percent_Identity=26.4550264550265, Blast_Score=68, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17536651, Length=170, Percent_Identity=27.6470588235294, Blast_Score=68, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6323882, Length=192, Percent_Identity=29.1666666666667, Blast_Score=86, Evalue=7e-18,
Organism=Saccharomyces cerevisiae, GI6322226, Length=187, Percent_Identity=29.4117647058824, Blast_Score=78, Evalue=9e-16,
Organism=Saccharomyces cerevisiae, GI6322227, Length=194, Percent_Identity=26.2886597938144, Blast_Score=66, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6319635, Length=188, Percent_Identity=25, Blast_Score=63, Evalue=4e-11,
Organism=Drosophila melanogaster, GI21357041, Length=188, Percent_Identity=29.2553191489362, Blast_Score=77, Evalue=6e-15,
Organism=Drosophila melanogaster, GI24644339, Length=189, Percent_Identity=29.6296296296296, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI23397609, Length=185, Percent_Identity=27.027027027027, Blast_Score=75, Evalue=2e-14,
Organism=Drosophila melanogaster, GI21355319, Length=204, Percent_Identity=24.5098039215686, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24640492, Length=170, Percent_Identity=28.8235294117647, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24639444, Length=193, Percent_Identity=26.9430051813472, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI281364892, Length=173, Percent_Identity=30.0578034682081, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI21358495, Length=191, Percent_Identity=27.7486910994764, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI28571526, Length=194, Percent_Identity=28.8659793814433, Blast_Score=71, Evalue=5e-13,
Organism=Drosophila melanogaster, GI281364494, Length=198, Percent_Identity=28.2828282828283, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24648693, Length=229, Percent_Identity=24.0174672489083, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI21355889, Length=229, Percent_Identity=24.0174672489083, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24584748, Length=185, Percent_Identity=24.8648648648649, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI161076933, Length=185, Percent_Identity=24.8648648648649, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24641232, Length=225, Percent_Identity=24.8888888888889, Blast_Score=64, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 24778; Mature: 24778

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKLILITGVSRGLGYALTERFIQEGHTIIGCARSQVTVEKLSHKFGSPHNFVAVDVADE
CEEEEEEECCCCCCHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHCCCCCEEEEEECCH
AQVKAWAELILKEYEPPDILINNAAIANQPAPLWEVPSTDFSQLIDINIKGVVHIIRYFI
HHHHHHHHHHHHHCCCCCEEEECCEECCCCCCCCCCCCCCHHHHEECCHHHHHHHHHHHH
PAMVQKRHGIIINLSSGWGRSTSPLVAPYCASKWAIEGLTRALAQELPAGMAAIPLNPGI
HHHHHHCCCEEEEECCCCCCCCCCEECHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCE
IHTDMLDICFGEEAVNYPPISQWVLKAVPFILQLKPTDNGVPLTVPS
EEHHHHHHHCCCCCCCCCCHHHHHHHHCCEEEEEECCCCCCEEEECC
>Mature Secondary Structure
MVKLILITGVSRGLGYALTERFIQEGHTIIGCARSQVTVEKLSHKFGSPHNFVAVDVADE
CEEEEEEECCCCCCHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHCCCCCEEEEEECCH
AQVKAWAELILKEYEPPDILINNAAIANQPAPLWEVPSTDFSQLIDINIKGVVHIIRYFI
HHHHHHHHHHHHHCCCCCEEEECCEECCCCCCCCCCCCCCHHHHEECCHHHHHHHHHHHH
PAMVQKRHGIIINLSSGWGRSTSPLVAPYCASKWAIEGLTRALAQELPAGMAAIPLNPGI
HHHHHHCCCEEEEECCCCCCCCCCEECHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCE
IHTDMLDICFGEEAVNYPPISQWVLKAVPFILQLKPTDNGVPLTVPS
EEHHHHHHHCCCCCCCCCCHHHHHHHHCCEEEEEECCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]