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The map label for this gene is rffM [H]

Identifier: 17229197

GI number: 17229197

Start: 2045637

End: 2046389

Strand: Direct

Name: rffM [H]

Synonym: alr1705

Alternate gene names: 17229197

Gene position: 2045637-2046389 (Clockwise)

Preceding gene: 17229192

Following gene: 17229198

Centisome position: 31.89

GC content: 43.96

Gene sequence:

>753_bases
ATGTTTCCATCATCTAAAGTGTTTTCAGTACTGGGAATTCCAGTTCATGTAATGAGTGACTATCCGAGTTGGTTACTGGA
ATGCCTGCGACAGGGGAAAGGCGCTCATGTAGTGACACTCAATGCAGAAATGACGATGCAGGCACAGCAAAATACATCAT
TGAACAACATAATTCAGAATGCTGAATTAGTAATTCCTGATGGTGCAGGAGTGGTGATGTATTTGCGGTGGCTTTGTTGG
CAAAAAGTCCAGCGCTGTCCGGGAATTGAACTGGCGGAAACTTTGTTAAAAGCAATCGGTCAAGAGCAAGCAGATAAAAC
TGTATTCTTCTATGGAGGAGCGCCAGGAGTAACTGCACAAGCGGCGAATGATTGGCAGCAAAAAATACCTAGTTTGAATA
TAGTAGGTACTCACTCCGGTTACCATTCTGCACAAGAAGAACAACAACTGCAAAAAACTCTCGCCCAATTACAACCACAG
GTAATTTTGGTTGGTTTGGGTGTTCCACGGCAAGAATTATGGATTGCCCAAAATCGTCACTTGTGTCCTCAAGCCATTTG
GATTGGTGTTGGTGGTAGTTTTGATATTTGGTCAGGAAGCAAAGATCGCGCCCCCGCTTGGTTGGCTAATAATAATTTGG
AATGGCTATATCGTTTATATAAAGAGCCTTGGCGTTGGCGGCGAATGTTGGCTCTGCCTCAGTTTGCGGTGAAAGCTTTT
GTTTACCGTTTGACTATGAAGGGTGCGATTTAG

Upstream 100 bases:

>100_bases
GCTTATTTGGATAAATTTACTCCTCTATCAGCCTAGAGGCAACCTATTAGAAAATTTGATAAACTATCGTCGAGAGAGTC
TGGTGTGAGGCTAAAGGGCT

Downstream 100 bases:

>100_bases
TACATCACTCACCCAAGAGATAGTACTTGCGCCATTTTGAAGATTAGAAAAATTTTAATTTTGAGTTTTGATTTTGGGAT
TCCCAGGCATGAGTTGGGAA

Product: UDP-N-acetyl-D-mannosaminuronic acid transferase

Products: NA

Alternate protein names: N-acetylglucosaminyldiphospho-undecaprenol N-acetyl-beta-D-mannosaminyltransferase; UDP-N-acetylmannosamine transferase [H]

Number of amino acids: Translated: 250; Mature: 250

Protein sequence:

>250_residues
MFPSSKVFSVLGIPVHVMSDYPSWLLECLRQGKGAHVVTLNAEMTMQAQQNTSLNNIIQNAELVIPDGAGVVMYLRWLCW
QKVQRCPGIELAETLLKAIGQEQADKTVFFYGGAPGVTAQAANDWQQKIPSLNIVGTHSGYHSAQEEQQLQKTLAQLQPQ
VILVGLGVPRQELWIAQNRHLCPQAIWIGVGGSFDIWSGSKDRAPAWLANNNLEWLYRLYKEPWRWRRMLALPQFAVKAF
VYRLTMKGAI

Sequences:

>Translated_250_residues
MFPSSKVFSVLGIPVHVMSDYPSWLLECLRQGKGAHVVTLNAEMTMQAQQNTSLNNIIQNAELVIPDGAGVVMYLRWLCW
QKVQRCPGIELAETLLKAIGQEQADKTVFFYGGAPGVTAQAANDWQQKIPSLNIVGTHSGYHSAQEEQQLQKTLAQLQPQ
VILVGLGVPRQELWIAQNRHLCPQAIWIGVGGSFDIWSGSKDRAPAWLANNNLEWLYRLYKEPWRWRRMLALPQFAVKAF
VYRLTMKGAI
>Mature_250_residues
MFPSSKVFSVLGIPVHVMSDYPSWLLECLRQGKGAHVVTLNAEMTMQAQQNTSLNNIIQNAELVIPDGAGVVMYLRWLCW
QKVQRCPGIELAETLLKAIGQEQADKTVFFYGGAPGVTAQAANDWQQKIPSLNIVGTHSGYHSAQEEQQLQKTLAQLQPQ
VILVGLGVPRQELWIAQNRHLCPQAIWIGVGGSFDIWSGSKDRAPAWLANNNLEWLYRLYKEPWRWRRMLALPQFAVKAF
VYRLTMKGAI

Specific function: Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, a key lipid intermediate in the de novo synthesis of teichoic acid (Potential) [H]

COG id: COG1922

COG function: function code M; Teichoic acid biosynthesis proteins

Gene ontology:

Cell location: Secreted, cell wall [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 26 family [H]

Homologues:

Organism=Escherichia coli, GI2367289, Length=202, Percent_Identity=34.6534653465347, Blast_Score=109, Evalue=2e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004629 [H]

Pfam domain/function: PF03808 Glyco_tran_WecB [H]

EC number: =2.4.1.187 [H]

Molecular weight: Translated: 28156; Mature: 28156

Theoretical pI: Translated: 9.15; Mature: 9.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFPSSKVFSVLGIPVHVMSDYPSWLLECLRQGKGAHVVTLNAEMTMQAQQNTSLNNIIQN
CCCCHHHHHHHCCCCEECCCCHHHHHHHHHCCCCCEEEEEECCEEEEHHHCCCHHHHHCC
AELVIPDGAGVVMYLRWLCWQKVQRCPGIELAETLLKAIGQEQADKTVFFYGGAPGVTAQ
CEEEEECCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCEEEEECCCCCCCHH
AANDWQQKIPSLNIVGTHSGYHSAQEEQQLQKTLAQLQPQVILVGLGVPRQELWIAQNRH
HHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHCCCC
LCPQAIWIGVGGSFDIWSGSKDRAPAWLANNNLEWLYRLYKEPWRWRRMLALPQFAVKAF
CCCEEEEEECCCCEECCCCCCCCCCEEEECCCHHHHHHHHHCHHHHHHHHHHHHHHHHHH
VYRLTMKGAI
HHHHHHCCCC
>Mature Secondary Structure
MFPSSKVFSVLGIPVHVMSDYPSWLLECLRQGKGAHVVTLNAEMTMQAQQNTSLNNIIQN
CCCCHHHHHHHCCCCEECCCCHHHHHHHHHCCCCCEEEEEECCEEEEHHHCCCHHHHHCC
AELVIPDGAGVVMYLRWLCWQKVQRCPGIELAETLLKAIGQEQADKTVFFYGGAPGVTAQ
CEEEEECCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCEEEEECCCCCCCHH
AANDWQQKIPSLNIVGTHSGYHSAQEEQQLQKTLAQLQPQVILVGLGVPRQELWIAQNRH
HHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHCCCC
LCPQAIWIGVGGSFDIWSGSKDRAPAWLANNNLEWLYRLYKEPWRWRRMLALPQFAVKAF
CCCEEEEEECCCCEECCCCCCCCCCEEEECCCHHHHHHHHHCHHHHHHHHHHHHHHHHHH
VYRLTMKGAI
HHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11882717 [H]