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The map label for this gene is xisA

Identifier: 17228937

GI number: 17228937

Start: 1700741

End: 1702159

Strand: Direct

Name: xisA

Synonym: alr1442

Alternate gene names: 17228937

Gene position: 1700741-1702159 (Clockwise)

Preceding gene: 17228936

Following gene: 17228938

Centisome position: 26.52

GC content: 38.27

Gene sequence:

>1419_bases
ATGCAAAATCAGGGTCAAGACAAATATCAACAAGCCTTTGCAGACTTAGAGCCACTTTCATCTACCGACGGCAGTTTTCT
CGGCTCAAGTCTGCAAGCACAGCAGCAAAGAGAACACATGAGAACAAAAGTACTACAAGACCTAGACAAGGTAAATCTGC
GTTTGAAGTCTGCAAAGACGAAAGTCTCAGTTCGAGAATCTAACGGAAGTCTGCAATTACGAGCAACGTTACCAATTAAA
CCTGGAGATAAGGACACCAACGGTACAGGCAGAAAGCAATACAATCTCAGCTTGAATATCCCTGCAAACTTGGATGGACT
GAAGACGGCTGAGGAAGAAGCTTATGAATTAGGTAAATTAATCGCTCGGAAAACCTTTGAATGGAATGATAAATATTTAG
GCAAAGAAGCCACTAAAAAAGATTCACAAACAATAGGTGATTTACTAGAAAAATTTGCAGAAGAGTATTTTAAAACCCAT
AAACGCACCACTAAAAGCGAACATACCTTTTTTTACTATTTTTCCCGCACCCAACGATATACCAATTCCAAAGATTTAGC
AACGGCGGAAAATCTCATCAATTCAATTGAGCAAATCGATAAAGAATGGGCGAGATATAATGCCGCCAGAGCCATATCAG
CTTTTTGCATAACATTCAATATAGAAATTGATTTGTCCCAGTATTCCAAAATGCCTGATCGCAATTCGCGCAACATCCCC
ACAGATGCAGAAATACTATCAGGAATTACCAAATTTGAAGACTATCTAGTTACCAGAGGAAATCAAGTTAATGAAGATGT
AAAAGATAGCTGGCAACTTTGGCGCTGGACATATGGAATGTTAGCAGTTTTTGGTTTACGCCCCAGGGAAATTTTTATTA
ACCCTAATATTGATTGGTGGTTAAGCAAAGAGAATATAGACCTCACATGGAAAGTAGACAAAGAATGTAAAACTGGTGAA
AGACAAGCATTACCCTTACATAAAGAATGGATTGATGAGTTTGATTTAAGAAATCCGAAATATTTAGAAATGCTGGCAAC
AGCAATTAGTAAAAAAGATAAAACAAATCATGCTGAAATAACAGCCTTAACTCAGCGTATTAGTTGGTGGTTTCGGAAAG
TCGAATTAGATTTTAAACCCTATGATTTACGTCACGCCTGGGCAATTAGAGCGCATATTTTAGGCATACCAATCAAAGCG
GCGGCTGATAATTTGGGGCATAGTATGCAGGTTCATACACAAACCTATCAGCGCTGGTTCTCGCTAGATATGCGGAAGTT
AGCGATTAATCAGGCTTTGACTAAGAGGAATGAATTTGAGGTGATTAGGGAGGAGAATGCTAAATTGCAGATAGAAAATG
AAAGGTTGAGGATGGAAATTGAGAAGTTAAAGATGGAAATAGCTTATAAGAATAGTTGA

Upstream 100 bases:

>100_bases
TTTCAACAGCTTAATGTTTGCACTGAGCAGTGTTAGTGATGAACATTGTTTGCTGATAACACATTAATTTTTAGGCTAAA
TATAGGCTAATACCACAGCG

Downstream 100 bases:

>100_bases
ATTTTATAAAAATAATCTGCTCAATGCTTACAGTAAAAAAAGCTTTAAATAATATTTAAAAAAAATACAATCATAAAATA
TGAGTAATTAATATCTTAAA

Product: nifD element site-specific recombinase

Products: NA

Alternate protein names: NifD element site-specific recombinase

Number of amino acids: Translated: 472; Mature: 472

Protein sequence:

>472_residues
MQNQGQDKYQQAFADLEPLSSTDGSFLGSSLQAQQQREHMRTKVLQDLDKVNLRLKSAKTKVSVRESNGSLQLRATLPIK
PGDKDTNGTGRKQYNLSLNIPANLDGLKTAEEEAYELGKLIARKTFEWNDKYLGKEATKKDSQTIGDLLEKFAEEYFKTH
KRTTKSEHTFFYYFSRTQRYTNSKDLATAENLINSIEQIDKEWARYNAARAISAFCITFNIEIDLSQYSKMPDRNSRNIP
TDAEILSGITKFEDYLVTRGNQVNEDVKDSWQLWRWTYGMLAVFGLRPREIFINPNIDWWLSKENIDLTWKVDKECKTGE
RQALPLHKEWIDEFDLRNPKYLEMLATAISKKDKTNHAEITALTQRISWWFRKVELDFKPYDLRHAWAIRAHILGIPIKA
AADNLGHSMQVHTQTYQRWFSLDMRKLAINQALTKRNEFEVIREENAKLQIENERLRMEIEKLKMEIAYKNS

Sequences:

>Translated_472_residues
MQNQGQDKYQQAFADLEPLSSTDGSFLGSSLQAQQQREHMRTKVLQDLDKVNLRLKSAKTKVSVRESNGSLQLRATLPIK
PGDKDTNGTGRKQYNLSLNIPANLDGLKTAEEEAYELGKLIARKTFEWNDKYLGKEATKKDSQTIGDLLEKFAEEYFKTH
KRTTKSEHTFFYYFSRTQRYTNSKDLATAENLINSIEQIDKEWARYNAARAISAFCITFNIEIDLSQYSKMPDRNSRNIP
TDAEILSGITKFEDYLVTRGNQVNEDVKDSWQLWRWTYGMLAVFGLRPREIFINPNIDWWLSKENIDLTWKVDKECKTGE
RQALPLHKEWIDEFDLRNPKYLEMLATAISKKDKTNHAEITALTQRISWWFRKVELDFKPYDLRHAWAIRAHILGIPIKA
AADNLGHSMQVHTQTYQRWFSLDMRKLAINQALTKRNEFEVIREENAKLQIENERLRMEIEKLKMEIAYKNS
>Mature_472_residues
MQNQGQDKYQQAFADLEPLSSTDGSFLGSSLQAQQQREHMRTKVLQDLDKVNLRLKSAKTKVSVRESNGSLQLRATLPIK
PGDKDTNGTGRKQYNLSLNIPANLDGLKTAEEEAYELGKLIARKTFEWNDKYLGKEATKKDSQTIGDLLEKFAEEYFKTH
KRTTKSEHTFFYYFSRTQRYTNSKDLATAENLINSIEQIDKEWARYNAARAISAFCITFNIEIDLSQYSKMPDRNSRNIP
TDAEILSGITKFEDYLVTRGNQVNEDVKDSWQLWRWTYGMLAVFGLRPREIFINPNIDWWLSKENIDLTWKVDKECKTGE
RQALPLHKEWIDEFDLRNPKYLEMLATAISKKDKTNHAEITALTQRISWWFRKVELDFKPYDLRHAWAIRAHILGIPIKA
AADNLGHSMQVHTQTYQRWFSLDMRKLAINQALTKRNEFEVIREENAKLQIENERLRMEIEKLKMEIAYKNS

Specific function: Essential for DNA excision. Site specific recombinase necessary for the excision of the 11 kb nifD element during heterocyst differentiation

COG id: COG0582

COG function: function code L; Integrase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xisA/xisC recombinase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): XISA_NOSS1 (P08862)

Other databases:

- EMBL:   U38537
- EMBL:   BA000019
- PIR:   A24782
- PIR:   AG1986
- RefSeq:   NP_485485.1
- ProteinModelPortal:   P08862
- STRING:   P08862
- GeneID:   1105037
- GenomeReviews:   BA000019_GR
- KEGG:   ana:alr1442
- NMPDR:   fig|103690.1.peg.1751
- eggNOG:   COG0582
- HOGENOM:   HBG581461
- OMA:   ININRAL
- ProtClustDB:   CLSK2518496
- BioCyc:   NSP103690:ALR1442-MONOMER
- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- Gene3D:   G3DSA:1.10.443.10

Pfam domain/function: PF00589 Phage_integrase; SSF56349 DNA_brk_join_enz

EC number: NA

Molecular weight: Translated: 55228; Mature: 55228

Theoretical pI: Translated: 9.29; Mature: 9.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQNQGQDKYQQAFADLEPLSSTDGSFLGSSLQAQQQREHMRTKVLQDLDKVNLRLKSAKT
CCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEECCCE
KVSVRESNGSLQLRATLPIKPGDKDTNGTGRKQYNLSLNIPANLDGLKTAEEEAYELGKL
EEEEEECCCCEEEEEEECCCCCCCCCCCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHH
IARKTFEWNDKYLGKEATKKDSQTIGDLLEKFAEEYFKTHKRTTKSEHTFFYYFSRTQRY
HHHCCCCCCCHHCCCHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECHHHC
TNSKDLATAENLINSIEQIDKEWARYNAARAISAFCITFNIEIDLSQYSKMPDRNSRNIP
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEEEEEHHHHHCCCCCCCCCCC
TDAEILSGITKFEDYLVTRGNQVNEDVKDSWQLWRWTYGMLAVFGLRPREIFINPNIDWW
CHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCEE
LSKENIDLTWKVDKECKTGERQALPLHKEWIDEFDLRNPKYLEMLATAISKKDKTNHAEI
EECCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCHHH
TALTQRISWWFRKVELDFKPYDLRHAWAIRAHILGIPIKAAADNLGHSMQVHTQTYQRWF
HHHHHHHHHHHHHEECCCCCCCCHHHHHHHHHHCCCCHHHHHHCCCCCEEEHHHHHHHHH
SLDMRKLAINQALTKRNEFEVIREENAKLQIENERLRMEIEKLKMEIAYKNS
HHHHHHHHHHHHHHCCCHHHHHHCCCCEEEEEHHHHHHHHHHHHEEEEECCC
>Mature Secondary Structure
MQNQGQDKYQQAFADLEPLSSTDGSFLGSSLQAQQQREHMRTKVLQDLDKVNLRLKSAKT
CCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEECCCE
KVSVRESNGSLQLRATLPIKPGDKDTNGTGRKQYNLSLNIPANLDGLKTAEEEAYELGKL
EEEEEECCCCEEEEEEECCCCCCCCCCCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHH
IARKTFEWNDKYLGKEATKKDSQTIGDLLEKFAEEYFKTHKRTTKSEHTFFYYFSRTQRY
HHHCCCCCCCHHCCCHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECHHHC
TNSKDLATAENLINSIEQIDKEWARYNAARAISAFCITFNIEIDLSQYSKMPDRNSRNIP
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEEEEEHHHHHCCCCCCCCCCC
TDAEILSGITKFEDYLVTRGNQVNEDVKDSWQLWRWTYGMLAVFGLRPREIFINPNIDWW
CHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCEE
LSKENIDLTWKVDKECKTGERQALPLHKEWIDEFDLRNPKYLEMLATAISKKDKTNHAEI
EECCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCHHH
TALTQRISWWFRKVELDFKPYDLRHAWAIRAHILGIPIKAAADNLGHSMQVHTQTYQRWF
HHHHHHHHHHHHHEECCCCCCCCHHHHHHHHHHCCCCHHHHHHCCCCCEEEHHHHHHHHH
SLDMRKLAINQALTKRNEFEVIREENAKLQIENERLRMEIEKLKMEIAYKNS
HHHHHHHHHHHHHHCCCHHHHHHCCCCEEEEEHHHHHHHHHHHHEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3006922; 11759840; 3144039