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The map label for this gene is prpC [H]

Identifier: 17228043

GI number: 17228043

Start: 639638

End: 641680

Strand: Direct

Name: prpC [H]

Synonym: alr0547

Alternate gene names: 17228043

Gene position: 639638-641680 (Clockwise)

Preceding gene: 17228042

Following gene: 17228044

Centisome position: 9.97

GC content: 44.2

Gene sequence:

>2043_bases
ATGCTGATTTGCCCTCAGTGTGAATTTGAAAACCCTAATGCTAACAAGTTTTGTCAAAAATGTGGTGCTTCTTTGTCCCA
CAAGGTTTGTTCTCAATGCAGCACTGAAGTACCAGTGAATGCTGAAAATTGCCATAACTGTGGTGCAGAAACCGGCACAG
TATGGCGGGCGATTATCGAGACGAAGGATTGGGCTTCTGACGTAAGTGTCAGCACTTTACTGAGCGCCAACTCTGTTGAT
GTAGCCTCCCACAAGGAAGAGCAAACAGAATTAGGGTTTGAGGAAGATGAAGAAGAGAAGATGATGCTGTCTCCATCATT
ATTCTCTGTTGGCTCATATTTGGATAAAGAACAACGCTATCAGATTTTGCAAGTGCTATCAGCCGCACATGATGAGGTTA
GCCTTAGGGTTTTGGACTGTCAACCATACCAATTATCACCAATTGAAGCAATATTAGCTAATCAGCAACAGGGGTTGGTG
ACTCCAGCAGTGGAAGCCAATGGTATTCCCAGTTTGGCTAGGGCTTATATGGTTTTACAATCCCAAAATCACACGGAAAT
TCCCCAGATTCATGATGCTTGGGAGGACGGCGATAACCAGATATTACTTATTGAAGACCGTTCTCACTACCAGTCTTTGC
TGGATTTATGGCAAAAGGAAACCACTAGTTCGCTAGAAATTTTACACTGGTTTTATCAAATGACCCAACTTTGGGTATTA
CTAGAACCATTAAAGTGTCACTACAGTTTGTGGGATTTGGCGAATTTGTGTTTAGATGAAGACCAGACAATTAGCTTACG
AAAACTGTACGTAAAACCACCTAAAAGCGAGTTAGCGATTGACTACTTACCACTGGATTTTAATCCTGAAACAGCACAAC
AAGAGGATGTAACATTGCCTATATTTGTGCAGCCCTCAAGTATTAAAGCCTTGGGAGAAGTTTGGCAGGCGCTATTTAGA
GAGTCTCAACGCACTCAATTTGGTTCCATCATCCAGATTTTAGGAGATTTGCAGCAGGGTAAGATTTACTCGATCGCTCA
GTTGCGATCGCGTTTACAAGAAGTCGCCACGGAACTAGAAGCAACTACGACCCCAATATTTGAGCCAATGGAAGCAGAAC
AAACGAATGCACCCACAGTCTTACAAGCAGATGATGTAGAAGATCCCTCTGGCAAGGGTGATGATATGCCCACAGTAGTG
CTGTCCGTGCAGTTAAGCAGTTTAGAAGATGCTGGTCGCACTGATGTTGGTCGTCAACGCCATCACAATGAGGACTACTT
TGGGATTGAAACTAAAACAGAAAAATTAGAACTGCCGAAAAACCGCATTCTACAAGCTCGTGGTTTGTATATTCTTTGTG
ATGGTATGGGCGGACACGCTGGCGGTGAAGTGGCTAGCGAGTTAGCCGTGATCACCTTACGCCAATACTTTCAGCAACAC
TGGACTGATAACCAATTACCAGCAGAAGAGATAATTCGTGAGTCAGTTTATCTGGCTAATCAAGCAATCTACGAAAAAAA
CCAACAAGAAGCCCGTTCTGGCGTAGGACGCATGGGTACTACTTTGGTAATGCTATTAGTTCAAGGTAGTCAAGCAGCAG
TTGCCCATGTGGGTGATAGCCGCCTCTACCGTGTGACTCGTAAGCGGGGGTTGGAACAAGTGACTGTAGATCATGAAGTT
GGTCAAAGAGAAATTGATCGAGGAGTAGAAGCAAGCATCGCTTATGCCCGTCCAGATGCTTACCAACTCACCCAGGCTTT
AGGCCCTCGTGATGAAACCGCCATTAATCCCAGTGTGGAGTTCTTTGATATCAATGAAGATAGCCTACTCGTTCTCGCTT
CCGATGGGTTATCTGATAACGATTTACTCGAAACTAACTGGCAAACTCACCTACTGCCATTATTAAGTTCTAGCGCTAAT
TTAGAGCAGGGAGTGGCAGAATTAATTGATCTGGCCAACCAATACAATGGTCATGACAACATTACTGCTATACTTGTCCG
GGCAAAAGTACGCCCAAATCTGGGGGAAGAGACTGGGGATTAA

Upstream 100 bases:

>100_bases
ACAACTTATTATGTCTACTATAGGCAAGGGCGGCCAGTTGTGGCACTTTGGATATTAGTGGCTAGAAGCACCTCGGAACG
GGAATTAAGGAACTTCCACT

Downstream 100 bases:

>100_bases
ATACTAAGGGTTATGAAGAAGCAAAGAGATAGGGTACAGGGGAGAAAACATTGACCTCATCCCTAATCCCAATCCCCAAT
CCCTAGTACCCAATCCCTAA

Product: putative protein serine/threonine phosphatase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 680; Mature: 680

Protein sequence:

>680_residues
MLICPQCEFENPNANKFCQKCGASLSHKVCSQCSTEVPVNAENCHNCGAETGTVWRAIIETKDWASDVSVSTLLSANSVD
VASHKEEQTELGFEEDEEEKMMLSPSLFSVGSYLDKEQRYQILQVLSAAHDEVSLRVLDCQPYQLSPIEAILANQQQGLV
TPAVEANGIPSLARAYMVLQSQNHTEIPQIHDAWEDGDNQILLIEDRSHYQSLLDLWQKETTSSLEILHWFYQMTQLWVL
LEPLKCHYSLWDLANLCLDEDQTISLRKLYVKPPKSELAIDYLPLDFNPETAQQEDVTLPIFVQPSSIKALGEVWQALFR
ESQRTQFGSIIQILGDLQQGKIYSIAQLRSRLQEVATELEATTTPIFEPMEAEQTNAPTVLQADDVEDPSGKGDDMPTVV
LSVQLSSLEDAGRTDVGRQRHHNEDYFGIETKTEKLELPKNRILQARGLYILCDGMGGHAGGEVASELAVITLRQYFQQH
WTDNQLPAEEIIRESVYLANQAIYEKNQQEARSGVGRMGTTLVMLLVQGSQAAVAHVGDSRLYRVTRKRGLEQVTVDHEV
GQREIDRGVEASIAYARPDAYQLTQALGPRDETAINPSVEFFDINEDSLLVLASDGLSDNDLLETNWQTHLLPLLSSSAN
LEQGVAELIDLANQYNGHDNITAILVRAKVRPNLGEETGD

Sequences:

>Translated_680_residues
MLICPQCEFENPNANKFCQKCGASLSHKVCSQCSTEVPVNAENCHNCGAETGTVWRAIIETKDWASDVSVSTLLSANSVD
VASHKEEQTELGFEEDEEEKMMLSPSLFSVGSYLDKEQRYQILQVLSAAHDEVSLRVLDCQPYQLSPIEAILANQQQGLV
TPAVEANGIPSLARAYMVLQSQNHTEIPQIHDAWEDGDNQILLIEDRSHYQSLLDLWQKETTSSLEILHWFYQMTQLWVL
LEPLKCHYSLWDLANLCLDEDQTISLRKLYVKPPKSELAIDYLPLDFNPETAQQEDVTLPIFVQPSSIKALGEVWQALFR
ESQRTQFGSIIQILGDLQQGKIYSIAQLRSRLQEVATELEATTTPIFEPMEAEQTNAPTVLQADDVEDPSGKGDDMPTVV
LSVQLSSLEDAGRTDVGRQRHHNEDYFGIETKTEKLELPKNRILQARGLYILCDGMGGHAGGEVASELAVITLRQYFQQH
WTDNQLPAEEIIRESVYLANQAIYEKNQQEARSGVGRMGTTLVMLLVQGSQAAVAHVGDSRLYRVTRKRGLEQVTVDHEV
GQREIDRGVEASIAYARPDAYQLTQALGPRDETAINPSVEFFDINEDSLLVLASDGLSDNDLLETNWQTHLLPLLSSSAN
LEQGVAELIDLANQYNGHDNITAILVRAKVRPNLGEETGD
>Mature_680_residues
MLICPQCEFENPNANKFCQKCGASLSHKVCSQCSTEVPVNAENCHNCGAETGTVWRAIIETKDWASDVSVSTLLSANSVD
VASHKEEQTELGFEEDEEEKMMLSPSLFSVGSYLDKEQRYQILQVLSAAHDEVSLRVLDCQPYQLSPIEAILANQQQGLV
TPAVEANGIPSLARAYMVLQSQNHTEIPQIHDAWEDGDNQILLIEDRSHYQSLLDLWQKETTSSLEILHWFYQMTQLWVL
LEPLKCHYSLWDLANLCLDEDQTISLRKLYVKPPKSELAIDYLPLDFNPETAQQEDVTLPIFVQPSSIKALGEVWQALFR
ESQRTQFGSIIQILGDLQQGKIYSIAQLRSRLQEVATELEATTTPIFEPMEAEQTNAPTVLQADDVEDPSGKGDDMPTVV
LSVQLSSLEDAGRTDVGRQRHHNEDYFGIETKTEKLELPKNRILQARGLYILCDGMGGHAGGEVASELAVITLRQYFQQH
WTDNQLPAEEIIRESVYLANQAIYEKNQQEARSGVGRMGTTLVMLLVQGSQAAVAHVGDSRLYRVTRKRGLEQVTVDHEV
GQREIDRGVEASIAYARPDAYQLTQALGPRDETAINPSVEFFDINEDSLLVLASDGLSDNDLLETNWQTHLLPLLSSSAN
LEQGVAELIDLANQYNGHDNITAILVRAKVRPNLGEETGD

Specific function: Protein phosphatase that dephosphorylates prkC and fusA (elongation factor G). PrpC and prkC are cotranscribed, which suggests that they form a functional couple in vivo, prpC's primary role being possibly to counter the action of prkC. May be involved in

COG id: COG0631

COG function: function code T; Serine/threonine protein phosphatase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PP2C-like domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015655
- InterPro:   IPR001932
- InterPro:   IPR014045 [H]

Pfam domain/function: PF00481 PP2C [H]

EC number: =3.1.3.16 [H]

Molecular weight: Translated: 75961; Mature: 75961

Theoretical pI: Translated: 4.29; Mature: 4.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLICPQCEFENPNANKFCQKCGASLSHKVCSQCSTEVPVNAENCHNCGAETGTVWRAIIE
CEECCCCCCCCCCHHHHHHHHCCHHHHHHHHHCCCCCCCCCHHHHCCCCCCHHHHHHHHH
TKDWASDVSVSTLLSANSVDVASHKEEQTELGFEEDEEEKMMLSPSLFSVGSYLDKEQRY
HHHHHCCCCHHHHHCCCCCCHHHCCHHHHHCCCCCCCCCCEEECCHHHHHHHHHCHHHHH
QILQVLSAAHDEVSLRVLDCQPYQLSPIEAILANQQQGLVTPAVEANGIPSLARAYMVLQ
HHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHH
SQNHTEIPQIHDAWEDGDNQILLIEDRSHYQSLLDLWQKETTSSLEILHWFYQMTQLWVL
CCCCCCCCCHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
LEPLKCHYSLWDLANLCLDEDQTISLRKLYVKPPKSELAIDYLPLDFNPETAQQEDVTLP
HHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCEEEEEECCCCCCCCCCCCCEEE
IFVQPSSIKALGEVWQALFRESQRTQFGSIIQILGDLQQGKIYSIAQLRSRLQEVATELE
EEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
ATTTPIFEPMEAEQTNAPTVLQADDVEDPSGKGDDMPTVVLSVQLSSLEDAGRTDVGRQR
HCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCEEEEEEEHHHHCCCCCCCCCHHH
HHNEDYFGIETKTEKLELPKNRILQARGLYILCDGMGGHAGGEVASELAVITLRQYFQQH
CCCCCEECCCCCHHHHCCCHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHH
WTDNQLPAEEIIRESVYLANQAIYEKNQQEARSGVGRMGTTLVMLLVQGSQAAVAHVGDS
CCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHCCCHHHHHHHHHHHCCCCEEEEECCCH
RLYRVTRKRGLEQVTVDHEVGQREIDRGVEASIAYARPDAYQLTQALGPRDETAINPSVE
HHHHHHHHCCCCEEECCHHHCHHHHHCCCCCEEEECCCCHHHHHHHCCCCCCCCCCCCEE
FFDINEDSLLVLASDGLSDNDLLETNWQTHLLPLLSSSANLEQGVAELIDLANQYNGHDN
EEECCCCCEEEEECCCCCCCCEECCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCC
ITAILVRAKVRPNLGEETGD
EEEEEEEEECCCCCCCCCCC
>Mature Secondary Structure
MLICPQCEFENPNANKFCQKCGASLSHKVCSQCSTEVPVNAENCHNCGAETGTVWRAIIE
CEECCCCCCCCCCHHHHHHHHCCHHHHHHHHHCCCCCCCCCHHHHCCCCCCHHHHHHHHH
TKDWASDVSVSTLLSANSVDVASHKEEQTELGFEEDEEEKMMLSPSLFSVGSYLDKEQRY
HHHHHCCCCHHHHHCCCCCCHHHCCHHHHHCCCCCCCCCCEEECCHHHHHHHHHCHHHHH
QILQVLSAAHDEVSLRVLDCQPYQLSPIEAILANQQQGLVTPAVEANGIPSLARAYMVLQ
HHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHH
SQNHTEIPQIHDAWEDGDNQILLIEDRSHYQSLLDLWQKETTSSLEILHWFYQMTQLWVL
CCCCCCCCCHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
LEPLKCHYSLWDLANLCLDEDQTISLRKLYVKPPKSELAIDYLPLDFNPETAQQEDVTLP
HHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCEEEEEECCCCCCCCCCCCCEEE
IFVQPSSIKALGEVWQALFRESQRTQFGSIIQILGDLQQGKIYSIAQLRSRLQEVATELE
EEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
ATTTPIFEPMEAEQTNAPTVLQADDVEDPSGKGDDMPTVVLSVQLSSLEDAGRTDVGRQR
HCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCEEEEEEEHHHHCCCCCCCCCHHH
HHNEDYFGIETKTEKLELPKNRILQARGLYILCDGMGGHAGGEVASELAVITLRQYFQQH
CCCCCEECCCCCHHHHCCCHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHH
WTDNQLPAEEIIRESVYLANQAIYEKNQQEARSGVGRMGTTLVMLLVQGSQAAVAHVGDS
CCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHCCCHHHHHHHHHHHCCCCEEEEECCCH
RLYRVTRKRGLEQVTVDHEVGQREIDRGVEASIAYARPDAYQLTQALGPRDETAINPSVE
HHHHHHHHCCCCEEECCHHHCHHHHHCCCCCEEEECCCCHHHHHHHCCCCCCCCCCCCEE
FFDINEDSLLVLASDGLSDNDLLETNWQTHLLPLLSSSANLEQGVAELIDLANQYNGHDN
EEECCCCCEEEEECCCCCCCCEECCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCC
ITAILVRAKVRPNLGEETGD
EEEEEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9534248; 9384377 [H]