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The map label for this gene is nahR [H]

Identifier: 17227849

GI number: 17227849

Start: 404006

End: 404923

Strand: Direct

Name: nahR [H]

Synonym: alr0353

Alternate gene names: 17227849

Gene position: 404006-404923 (Clockwise)

Preceding gene: 17227844

Following gene: 17227850

Centisome position: 6.3

GC content: 42.37

Gene sequence:

>918_bases
ATGGGATTAATAGATTTATCTTCCATTGACCTCAACCTACTGGTTACGTTTGAGGTGCTTTTTGAAGAGCGAAGTGTGAC
AGCAGCAGCCCAACGCTTGTATTTAGGACAACCAGCTATGAGTGCGGCTCTTGCAAGGCTACGAATACTATTTCAGGATG
AATTATTCATCCGTATTGGTCGGGAAATGCAGCCGACAGCAAAAGCTCTAGAAATTTCTCCAGGTATATCAGTTGCGCTC
CAGCAGATTCGACAGACATTAGAATCTAGTCAAACCTTTGACCCAACAACTTCTAAACATACCTTTGCCATTGGTAGTTC
GGACTACACCAGCTATGTTGTTCTACCCAAGTTGTTAGAGGTTTGTCGCCAGGTTGCACCAAGCATTGATTTTCGACTAA
TTGGTTTTGAGAAAGATAGTGTAGGAGACCTGTTAGAACAACGAGAAATTCATGTTGCGTTGGGTTTGTTTCAAAATCCA
CCCCGACAAACAAGACAAATGCCATTATTTGAAGAACACTTTGTTGGTCTTTGTCGGCGTGGACATCCTGTTGTTACTCA
GGAGAGTATGACACCGGAAACCTTTGCTCGTCTCCCTCAAGCTCTTTTTACTCTCCGAAGAGATGACATTGGTGAAATTG
ATAAGGTGCTTGCTCAATACAATCTTCAGCGTCGAGTCGTGTTGACTACCCCCCATTTGCTCATCTTGCCAACTGTCATT
TCATCTAGCGACTTGGTGACTGTCATTCCTTCACGACTGCTGACACCATTTGCTTATAAAGATACACTAGAAATTTTTGA
ACTTCCTGTAAAAACTGAACCTTGGATGATTTCTATGTTGTGGAGTAAACTTACAGATCAGGATCAAGCGAGTATTTGGT
TACGGCAGATGCTCAAAAGTGTTTGTGAGGGAATTTAA

Upstream 100 bases:

>100_bases
CTTTTGTTCCGTCATTTTTGTGACCTAAAGAATGCTTTTAGGTTTACTGTACTGAGATGTTATAAATTAAGCAAATTGAT
TGCAGCGATATATTTTATTA

Downstream 100 bases:

>100_bases
TCTAAATCTCCGCAGAATAAGCTTCATCTACTTTCAATGTTGTCCCTGTAATGAATTTGGCATTATCGGAAATCAGGAAA
GCAACTGTTTTGGCAAACTC

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 305; Mature: 304

Protein sequence:

>305_residues
MGLIDLSSIDLNLLVTFEVLFEERSVTAAAQRLYLGQPAMSAALARLRILFQDELFIRIGREMQPTAKALEISPGISVAL
QQIRQTLESSQTFDPTTSKHTFAIGSSDYTSYVVLPKLLEVCRQVAPSIDFRLIGFEKDSVGDLLEQREIHVALGLFQNP
PRQTRQMPLFEEHFVGLCRRGHPVVTQESMTPETFARLPQALFTLRRDDIGEIDKVLAQYNLQRRVVLTTPHLLILPTVI
SSSDLVTVIPSRLLTPFAYKDTLEIFELPVKTEPWMISMLWSKLTDQDQASIWLRQMLKSVCEGI

Sequences:

>Translated_305_residues
MGLIDLSSIDLNLLVTFEVLFEERSVTAAAQRLYLGQPAMSAALARLRILFQDELFIRIGREMQPTAKALEISPGISVAL
QQIRQTLESSQTFDPTTSKHTFAIGSSDYTSYVVLPKLLEVCRQVAPSIDFRLIGFEKDSVGDLLEQREIHVALGLFQNP
PRQTRQMPLFEEHFVGLCRRGHPVVTQESMTPETFARLPQALFTLRRDDIGEIDKVLAQYNLQRRVVLTTPHLLILPTVI
SSSDLVTVIPSRLLTPFAYKDTLEIFELPVKTEPWMISMLWSKLTDQDQASIWLRQMLKSVCEGI
>Mature_304_residues
GLIDLSSIDLNLLVTFEVLFEERSVTAAAQRLYLGQPAMSAALARLRILFQDELFIRIGREMQPTAKALEISPGISVALQ
QIRQTLESSQTFDPTTSKHTFAIGSSDYTSYVVLPKLLEVCRQVAPSIDFRLIGFEKDSVGDLLEQREIHVALGLFQNPP
RQTRQMPLFEEHFVGLCRRGHPVVTQESMTPETFARLPQALFTLRRDDIGEIDKVLAQYNLQRRVVLTTPHLLILPTVIS
SSDLVTVIPSRLLTPFAYKDTLEIFELPVKTEPWMISMLWSKLTDQDQASIWLRQMLKSVCEGI

Specific function: Regulates the expression of the naphthalene (nahA-F) and salicylate (nahG-M) metabolism genes [H]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081684, Length=305, Percent_Identity=25.9016393442623, Blast_Score=120, Evalue=8e-29,
Organism=Escherichia coli, GI87081766, Length=284, Percent_Identity=25.3521126760563, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1786820, Length=274, Percent_Identity=27.7372262773723, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI1790147, Length=299, Percent_Identity=23.0769230769231, Blast_Score=66, Evalue=3e-12,

Paralogues:

None

Copy number: 825 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34556; Mature: 34424

Theoretical pI: Translated: 5.71; Mature: 5.71

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGLIDLSSIDLNLLVTFEVLFEERSVTAAAQRLYLGQPAMSAALARLRILFQDELFIRIG
CCCCCCCCCCEEHEEHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHC
REMQPTAKALEISPGISVALQQIRQTLESSQTFDPTTSKHTFAIGSSDYTSYVVLPKLLE
CCCCCCHHHEECCCCHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHH
VCRQVAPSIDFRLIGFEKDSVGDLLEQREIHVALGLFQNPPRQTRQMPLFEEHFVGLCRR
HHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHEEHHHCCCCHHHHCCCCHHHHHHHHHHC
GHPVVTQESMTPETFARLPQALFTLRRDDIGEIDKVLAQYNLQRRVVLTTPHLLILPTVI
CCCCEECCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEEEECCCCEEEEHHH
SSSDLVTVIPSRLLTPFAYKDTLEIFELPVKTEPWMISMLWSKLTDQDQASIWLRQMLKS
CCCCHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHH
VCEGI
HHCCC
>Mature Secondary Structure 
GLIDLSSIDLNLLVTFEVLFEERSVTAAAQRLYLGQPAMSAALARLRILFQDELFIRIG
CCCCCCCCCEEHEEHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHC
REMQPTAKALEISPGISVALQQIRQTLESSQTFDPTTSKHTFAIGSSDYTSYVVLPKLLE
CCCCCCHHHEECCCCHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHH
VCRQVAPSIDFRLIGFEKDSVGDLLEQREIHVALGLFQNPPRQTRQMPLFEEHFVGLCRR
HHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHEEHHHCCCCHHHHCCCCHHHHHHHHHHC
GHPVVTQESMTPETFARLPQALFTLRRDDIGEIDKVLAQYNLQRRVVLTTPHLLILPTVI
CCCCEECCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEEEECCCCEEEEHHH
SSSDLVTVIPSRLLTPFAYKDTLEIFELPVKTEPWMISMLWSKLTDQDQASIWLRQMLKS
CCCCHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHH
VCEGI
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2703465; 2848005 [H]