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The map label for this gene is gcp [H]

Identifier: 17227606

GI number: 17227606

Start: 111955

End: 112995

Strand: Direct

Name: gcp [H]

Synonym: alr0110

Alternate gene names: 17227606

Gene position: 111955-112995 (Clockwise)

Preceding gene: 17227602

Following gene: 17227609

Centisome position: 1.75

GC content: 48.9

Gene sequence:

>1041_bases
ATGACAACTGTTTTAGCAATCGAAACCAGCTGTGATGAAACTGCCGTGGCAATTGTAAACAATCGTCAAGTTTTGAGTAG
TATCATAGCCTCGCAAATTTCCGTCCATCAGCAGTATGGTGGGGTAGTACCTGAAGTAGCCTCACGAGCGCACTTGGAAA
CGATAAATGGCGCGATCGCCCAAGCGATGGATCAAGCTCAACTAGGTTGGGATAAAATCGATGCGATCGCCGCCACTTGT
GCGCCTGGACTTGTAGGCGCGCTGTTAGTGGGGCTGACTGCTGCCAAAACTTTAGCAATCTTACACAACAAACCATTTTT
GGGAGTTCACCACCTCGAAGGTCACATCTACGCGACTTATTTGAGTGAGCCAACTTTAGATCCCCCTTTTCTTAGCTTAC
TGGTTTCTGGGGGACATACAAGCTTAATTTACGTTAAGGAATGTGGTAGGTATGAAAGTCTGGGTGAAACGCGTGATGAT
GCGGCTGGGGAAGCTTTTGACAAGGTAGCTAGGCTGTTAAAGCTAGGTTATCCTGGTGGCCCAGTCATTGATAAACTAGC
GCAAACAGGGAATCCTCAAGCCTTTGCGTTGCCTGAAGGAAAAGTGTCCTTGCCTGGTGGGGGATATCATCCCTATGATG
GCAGTTTTAGCGGCTTAAAGACGGCTGTACTTCGTCTAGTGCAGCAATTAGAGAAAGATGGCGATTCACTGCCTTTAGAG
GACATTGCCGCTAGCTTTCAGGCGACCGTAGCCAAGGCATTAACCAAGAGAGCGATCGCCTGTGCTTTAGATTATGGTCT
AGATACCATTGCCGTTGGTGGCGGGGTAGCCGCTAACAGTGGCTTGAGACAACACTTACAAGCAGCCACCGCCGCAAATA
ACCTCCGTGTCCTCTTCCCTCCGCTAAAATTCTGTACCGATAACGCCGCCATGATAGCCTGTGCAGCCGTAGACCACTTA
TCACGCGGACATACTTCCCCCATCACCTTAGGCGTGGAATCAAGGCTAAGTCTTAGCCAAGTGATGAAGTTATATCAGTA
G

Upstream 100 bases:

>100_bases
ATGGGGACTGGGGAAGTGGAGGGAAAAGAACATCCTTGACTTACTCATCTGCCTCATCTGCCTCATGTCCCCACTCAGCA
CTCCTTACTTCTTCGTAGCA

Downstream 100 bases:

>100_bases
TTGTCAGAGACGCGATTAATCGCGTCTGTACAGTAGTCAGTTGTTCATCTTTGGCTGTTGACCGATTACCAATTACCAAT
TACCAATGACTTAATATGAC

Product: putative DNA-binding/iron metalloprotein/AP endonuclease

Products: NA

Alternate protein names: Glycoprotease [H]

Number of amino acids: Translated: 346; Mature: 345

Protein sequence:

>346_residues
MTTVLAIETSCDETAVAIVNNRQVLSSIIASQISVHQQYGGVVPEVASRAHLETINGAIAQAMDQAQLGWDKIDAIAATC
APGLVGALLVGLTAAKTLAILHNKPFLGVHHLEGHIYATYLSEPTLDPPFLSLLVSGGHTSLIYVKECGRYESLGETRDD
AAGEAFDKVARLLKLGYPGGPVIDKLAQTGNPQAFALPEGKVSLPGGGYHPYDGSFSGLKTAVLRLVQQLEKDGDSLPLE
DIAASFQATVAKALTKRAIACALDYGLDTIAVGGGVAANSGLRQHLQAATAANNLRVLFPPLKFCTDNAAMIACAAVDHL
SRGHTSPITLGVESRLSLSQVMKLYQ

Sequences:

>Translated_346_residues
MTTVLAIETSCDETAVAIVNNRQVLSSIIASQISVHQQYGGVVPEVASRAHLETINGAIAQAMDQAQLGWDKIDAIAATC
APGLVGALLVGLTAAKTLAILHNKPFLGVHHLEGHIYATYLSEPTLDPPFLSLLVSGGHTSLIYVKECGRYESLGETRDD
AAGEAFDKVARLLKLGYPGGPVIDKLAQTGNPQAFALPEGKVSLPGGGYHPYDGSFSGLKTAVLRLVQQLEKDGDSLPLE
DIAASFQATVAKALTKRAIACALDYGLDTIAVGGGVAANSGLRQHLQAATAANNLRVLFPPLKFCTDNAAMIACAAVDHL
SRGHTSPITLGVESRLSLSQVMKLYQ
>Mature_345_residues
TTVLAIETSCDETAVAIVNNRQVLSSIIASQISVHQQYGGVVPEVASRAHLETINGAIAQAMDQAQLGWDKIDAIAATCA
PGLVGALLVGLTAAKTLAILHNKPFLGVHHLEGHIYATYLSEPTLDPPFLSLLVSGGHTSLIYVKECGRYESLGETRDDA
AGEAFDKVARLLKLGYPGGPVIDKLAQTGNPQAFALPEGKVSLPGGGYHPYDGSFSGLKTAVLRLVQQLEKDGDSLPLED
IAASFQATVAKALTKRAIACALDYGLDTIAVGGGVAANSGLRQHLQAATAANNLRVLFPPLKFCTDNAAMIACAAVDHLS
RGHTSPITLGVESRLSLSQVMKLYQ

Specific function: Could Be A Metalloprotease. [C]

COG id: COG0533

COG function: function code O; Metal-dependent proteases with possible chaperone activity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M22 family [H]

Homologues:

Organism=Homo sapiens, GI116812636, Length=342, Percent_Identity=35.3801169590643, Blast_Score=160, Evalue=2e-39,
Organism=Homo sapiens, GI8923380, Length=353, Percent_Identity=31.1614730878187, Blast_Score=125, Evalue=4e-29,
Organism=Escherichia coli, GI1789445, Length=342, Percent_Identity=42.9824561403509, Blast_Score=245, Evalue=3e-66,
Organism=Caenorhabditis elegans, GI17557464, Length=329, Percent_Identity=33.1306990881459, Blast_Score=149, Evalue=2e-36,
Organism=Caenorhabditis elegans, GI71995670, Length=334, Percent_Identity=33.2335329341317, Blast_Score=114, Evalue=1e-25,
Organism=Saccharomyces cerevisiae, GI6320099, Length=346, Percent_Identity=30.3468208092486, Blast_Score=126, Evalue=5e-30,
Organism=Saccharomyces cerevisiae, GI6322891, Length=298, Percent_Identity=29.5302013422819, Blast_Score=84, Evalue=3e-17,
Organism=Drosophila melanogaster, GI20129063, Length=346, Percent_Identity=35.8381502890173, Blast_Score=182, Evalue=4e-46,
Organism=Drosophila melanogaster, GI21357207, Length=344, Percent_Identity=29.3604651162791, Blast_Score=125, Evalue=5e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022450
- InterPro:   IPR000905
- InterPro:   IPR017860
- InterPro:   IPR017861 [H]

Pfam domain/function: PF00814 Peptidase_M22 [H]

EC number: =3.4.24.57 [H]

Molecular weight: Translated: 36273; Mature: 36142

Theoretical pI: Translated: 6.43; Mature: 6.43

Prosite motif: PS01016 GLYCOPROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTVLAIETSCDETAVAIVNNRQVLSSIIASQISVHQQYGGVVPEVASRAHLETINGAIA
CCEEEEEECCCCCEEEEEECCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
QAMDQAQLGWDKIDAIAATCAPGLVGALLVGLTAAKTLAILHNKPFLGVHHLEGHIYATY
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCEEEEEE
LSEPTLDPPFLSLLVSGGHTSLIYVKECGRYESLGETRDDAAGEAFDKVARLLKLGYPGG
ECCCCCCCHHHHHHHCCCCEEEEEEECCCCHHHCCCCCCHHHHHHHHHHHHHHHCCCCCC
PVIDKLAQTGNPQAFALPEGKVSLPGGGYHPYDGSFSGLKTAVLRLVQQLEKDGDSLPLE
HHHHHHHHCCCCCEEECCCCCEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHH
DIAASFQATVAKALTKRAIACALDYGLDTIAVGGGVAANSGLRQHLQAATAANNLRVLFP
HHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHCCCCEEEEC
PLKFCTDNAAMIACAAVDHLSRGHTSPITLGVESRLSLSQVMKLYQ
CHHHHCCCHHHHHHHHHHHHHCCCCCCEEECHHHHCCHHHHHHHHC
>Mature Secondary Structure 
TTVLAIETSCDETAVAIVNNRQVLSSIIASQISVHQQYGGVVPEVASRAHLETINGAIA
CEEEEEECCCCCEEEEEECCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
QAMDQAQLGWDKIDAIAATCAPGLVGALLVGLTAAKTLAILHNKPFLGVHHLEGHIYATY
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCEEEEEE
LSEPTLDPPFLSLLVSGGHTSLIYVKECGRYESLGETRDDAAGEAFDKVARLLKLGYPGG
ECCCCCCCHHHHHHHCCCCEEEEEEECCCCHHHCCCCCCHHHHHHHHHHHHHHHCCCCCC
PVIDKLAQTGNPQAFALPEGKVSLPGGGYHPYDGSFSGLKTAVLRLVQQLEKDGDSLPLE
HHHHHHHHCCCCCEEECCCCCEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHH
DIAASFQATVAKALTKRAIACALDYGLDTIAVGGGVAANSGLRQHLQAATAANNLRVLFP
HHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHCCCCEEEEC
PLKFCTDNAAMIACAAVDHLSRGHTSPITLGVESRLSLSQVMKLYQ
CHHHHCCCHHHHHHHHHHHHHCCCCCCEEECHHHHCCHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA