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The map label for this gene is yhcK [H]

Identifier: 172087714

GI number: 172087714

Start: 1689964

End: 1691412

Strand: Reverse

Name: yhcK [H]

Synonym: VF_1515

Alternate gene names: 172087714

Gene position: 1691412-1689964 (Counterclockwise)

Preceding gene: 59712126

Following gene: 59712121

Centisome position: 58.37

GC content: 35.68

Gene sequence:

>1449_bases
ATGAGGTTCGTTTATCTATCCGATTTGGATAATAATCAAAAGAATTTCTATAAAGAAGCAGATAGACAGTCAGCACTGCT
TTCAATGTTAATAGAGAAAGATATTGATTTTATAGGTGCAGGGGCAAACTTCTATCAAGTTGGCAGTAAAAAGGATTGGT
CTCAGTTTCCTTTGTTTGCGGATTCATTATTGCATCGTTCTAATAGTCTTATTTCACTTCAATGGATGGAGAAAGTTGAA
GAAAAAGACATTGATGAACATTTTCAACAAATACATAAAAACTACCCTTTAGCTAAATTATATACGGTTCCAAAAGACCA
ACCTAAAACCTATGGTTATGTGATGAAAAATCATGAGCCTATTTATATCGCAACCGATATTTATCCAAGAGATGAGAAGA
ACACGCCTTTAATTGGATTTTATTCATCAAGAGAGCGTTTTAACCTCGTAGTTGAAGAGTTTTTAACTACGGGCCGCCCG
AGTGTTTCAGATAAAATTCGTTTATTGCAAGATAGCCTTGATCAAAGCGCACAAAAAACAGGCATGCTAGTTTATCATCC
TGTATTTACTTCAGATAAAACAGCGTTAAAAGGGGTAATGGTTGGTGTCGTAAGAATTACCAGTTATTTTGACCGTTTAG
TTAATTCCACCTCATTAGGTGAAGAGTTGGTTGTACGCATTATTGATACGGGATTTGATGCTGGTGATGATCCTATTATG
TATCAAAGCAGTACGTGGAATAATTTCAAAGGAGTGGATTACACTACTAGCGTAAAAATCGAAAATCGCCTTTGGAAAAT
AGAATATAAGTCTGATAATAAATTAAATGAATATCAAAGACTTACGTTGATTTGGTTGTTTTTCGGTATCTTAACCATTT
CAATGCTTATTGCGGCACTCACTTCAGTTGTTACTCGAGATAAACAACGAATTGAAAATTTACTCGAAATTAGAACCAAA
GAATTACGTTACATGGCAATGCATGATGATCTTACAGGATTATTAAACAGACGTGCTATACGAGATGTTATTACTCGTTA
CATAGAAGCTGAAAAGCCGTTTGCTTTATTGTGTTTTGATATCGATAAGTTTAAACAAATCAACGATACATATGGCCATC
CCGAAGGGGATGAAGTATTGCGACATATTGGGCACCTAATGTCTGAAACATTAGGAAATAATGTCCACGTTTCACGTCTT
GGAGGAGATGAATTCTCTATTGTGTTGAAACTGAACAATATTGATGAATTAACGTTAATTTCAGAACAAATTCATGATCT
CGTCGCTACATCCCCAACGGTGTTTAATGATTTCGAAATTGCTCAAACAATCAGTCTTGGTGCTGTCCTTTGGCAAGGAG
AAACACTTGAAGAGTTGTTGAAGGCTGCTGATCAAGCGTTATATCAAAGTAAAACGATGGGGCGTAATCAAGTTACCATT
CGAGGCTGA

Upstream 100 bases:

>100_bases
ATTAAAGGGTTATCAACCGTTGGAGAGCAGAGTGTTTAAGAGTAATTACTTTTATGTAATGACCAGTTTTTTGTTAGCTC
TATCTCTAGGTCTATTAAGT

Downstream 100 bases:

>100_bases
ATTTTCAGCAATCAAATCTCATAGTGTCGCGCTTAGCGCTGAGTTTAGGTAGAATAGCGCTTCGCCTTTTATTGTGTACC
AAGGATCTTCATGAACTTTA

Product: GGDEF domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 482; Mature: 482

Protein sequence:

>482_residues
MRFVYLSDLDNNQKNFYKEADRQSALLSMLIEKDIDFIGAGANFYQVGSKKDWSQFPLFADSLLHRSNSLISLQWMEKVE
EKDIDEHFQQIHKNYPLAKLYTVPKDQPKTYGYVMKNHEPIYIATDIYPRDEKNTPLIGFYSSRERFNLVVEEFLTTGRP
SVSDKIRLLQDSLDQSAQKTGMLVYHPVFTSDKTALKGVMVGVVRITSYFDRLVNSTSLGEELVVRIIDTGFDAGDDPIM
YQSSTWNNFKGVDYTTSVKIENRLWKIEYKSDNKLNEYQRLTLIWLFFGILTISMLIAALTSVVTRDKQRIENLLEIRTK
ELRYMAMHDDLTGLLNRRAIRDVITRYIEAEKPFALLCFDIDKFKQINDTYGHPEGDEVLRHIGHLMSETLGNNVHVSRL
GGDEFSIVLKLNNIDELTLISEQIHDLVATSPTVFNDFEIAQTISLGAVLWQGETLEELLKAADQALYQSKTMGRNQVTI
RG

Sequences:

>Translated_482_residues
MRFVYLSDLDNNQKNFYKEADRQSALLSMLIEKDIDFIGAGANFYQVGSKKDWSQFPLFADSLLHRSNSLISLQWMEKVE
EKDIDEHFQQIHKNYPLAKLYTVPKDQPKTYGYVMKNHEPIYIATDIYPRDEKNTPLIGFYSSRERFNLVVEEFLTTGRP
SVSDKIRLLQDSLDQSAQKTGMLVYHPVFTSDKTALKGVMVGVVRITSYFDRLVNSTSLGEELVVRIIDTGFDAGDDPIM
YQSSTWNNFKGVDYTTSVKIENRLWKIEYKSDNKLNEYQRLTLIWLFFGILTISMLIAALTSVVTRDKQRIENLLEIRTK
ELRYMAMHDDLTGLLNRRAIRDVITRYIEAEKPFALLCFDIDKFKQINDTYGHPEGDEVLRHIGHLMSETLGNNVHVSRL
GGDEFSIVLKLNNIDELTLISEQIHDLVATSPTVFNDFEIAQTISLGAVLWQGETLEELLKAADQALYQSKTMGRNQVTI
RG
>Mature_482_residues
MRFVYLSDLDNNQKNFYKEADRQSALLSMLIEKDIDFIGAGANFYQVGSKKDWSQFPLFADSLLHRSNSLISLQWMEKVE
EKDIDEHFQQIHKNYPLAKLYTVPKDQPKTYGYVMKNHEPIYIATDIYPRDEKNTPLIGFYSSRERFNLVVEEFLTTGRP
SVSDKIRLLQDSLDQSAQKTGMLVYHPVFTSDKTALKGVMVGVVRITSYFDRLVNSTSLGEELVVRIIDTGFDAGDDPIM
YQSSTWNNFKGVDYTTSVKIENRLWKIEYKSDNKLNEYQRLTLIWLFFGILTISMLIAALTSVVTRDKQRIENLLEIRTK
ELRYMAMHDDLTGLLNRRAIRDVITRYIEAEKPFALLCFDIDKFKQINDTYGHPEGDEVLRHIGHLMSETLGNNVHVSRL
GGDEFSIVLKLNNIDELTLISEQIHDLVATSPTVFNDFEIAQTISLGAVLWQGETLEELLKAADQALYQSKTMGRNQVTI
RG

Specific function: Unknown

COG id: COG3614

COG function: function code T; Predicted periplasmic ligand-binding sensor domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GGDEF domain [H]

Homologues:

Organism=Escherichia coli, GI145693134, Length=241, Percent_Identity=32.3651452282158, Blast_Score=104, Evalue=2e-23,
Organism=Escherichia coli, GI1787262, Length=167, Percent_Identity=33.5329341317365, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI87081881, Length=165, Percent_Identity=35.7575757575758, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI87082007, Length=211, Percent_Identity=31.2796208530806, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI1788956, Length=162, Percent_Identity=36.4197530864198, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1788381, Length=205, Percent_Identity=31.219512195122, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI1786584, Length=202, Percent_Identity=30.1980198019802, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1787816, Length=153, Percent_Identity=33.3333333333333, Blast_Score=79, Evalue=7e-16,
Organism=Escherichia coli, GI1787056, Length=261, Percent_Identity=29.1187739463602, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1787541, Length=170, Percent_Identity=30.5882352941176, Blast_Score=76, Evalue=5e-15,
Organism=Escherichia coli, GI1788085, Length=165, Percent_Identity=29.6969696969697, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1787802, Length=168, Percent_Identity=30.3571428571429, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI87081974, Length=148, Percent_Identity=29.0540540540541, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI87081977, Length=185, Percent_Identity=32.972972972973, Blast_Score=65, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR011620 [H]

Pfam domain/function: PF07694 5TM-5TMR_LYT; PF00990 GGDEF [H]

EC number: NA

Molecular weight: Translated: 55480; Mature: 55480

Theoretical pI: Translated: 5.51; Mature: 5.51

Prosite motif: PS50839 CHASE ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFVYLSDLDNNQKNFYKEADRQSALLSMLIEKDIDFIGAGANFYQVGSKKDWSQFPLFA
CEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCEEECCCCCCCHHCCHHH
DSLLHRSNSLISLQWMEKVEEKDIDEHFQQIHKNYPLAKLYTVPKDQPKTYGYVMKNHEP
HHHHHCCCCEEEHHHHHHHHHCCHHHHHHHHHHCCCCEEEEECCCCCCCCCCEEEECCCC
IYIATDIYPRDEKNTPLIGFYSSRERFNLVVEEFLTTGRPSVSDKIRLLQDSLDQSAQKT
EEEEECCCCCCCCCCCEEEEECCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHC
GMLVYHPVFTSDKTALKGVMVGVVRITSYFDRLVNSTSLGEELVVRIIDTGFDAGDDPIM
CEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCEE
YQSSTWNNFKGVDYTTSVKIENRLWKIEYKSDNKLNEYQRLTLIWLFFGILTISMLIAAL
EECCCCCCCCCCCEEEEEEEECEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
TSVVTRDKQRIENLLEIRTKELRYMAMHDDLTGLLNRRAIRDVITRYIEAEKPFALLCFD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEE
IDKFKQINDTYGHPEGDEVLRHIGHLMSETLGNNVHVSRLGGDEFSIVLKLNNIDELTLI
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCEEEEEEECCCCHHHHH
SEQIHDLVATSPTVFNDFEIAQTISLGAVLWQGETLEELLKAADQALYQSKTMGRNQVTI
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHEECCHHHHHHHHHHHHHHHHHHCCCCCEEEE
RG
EC
>Mature Secondary Structure
MRFVYLSDLDNNQKNFYKEADRQSALLSMLIEKDIDFIGAGANFYQVGSKKDWSQFPLFA
CEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCEEECCCCCCCHHCCHHH
DSLLHRSNSLISLQWMEKVEEKDIDEHFQQIHKNYPLAKLYTVPKDQPKTYGYVMKNHEP
HHHHHCCCCEEEHHHHHHHHHCCHHHHHHHHHHCCCCEEEEECCCCCCCCCCEEEECCCC
IYIATDIYPRDEKNTPLIGFYSSRERFNLVVEEFLTTGRPSVSDKIRLLQDSLDQSAQKT
EEEEECCCCCCCCCCCEEEEECCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHC
GMLVYHPVFTSDKTALKGVMVGVVRITSYFDRLVNSTSLGEELVVRIIDTGFDAGDDPIM
CEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCEE
YQSSTWNNFKGVDYTTSVKIENRLWKIEYKSDNKLNEYQRLTLIWLFFGILTISMLIAAL
EECCCCCCCCCCCEEEEEEEECEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
TSVVTRDKQRIENLLEIRTKELRYMAMHDDLTGLLNRRAIRDVITRYIEAEKPFALLCFD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEE
IDKFKQINDTYGHPEGDEVLRHIGHLMSETLGNNVHVSRLGGDEFSIVLKLNNIDELTLI
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCEEEEEEECCCCHHHHH
SEQIHDLVATSPTVFNDFEIAQTISLGAVLWQGETLEELLKAADQALYQSKTMGRNQVTI
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHEECCHHHHHHHHHHHHHHHHHHCCCCCEEEE
RG
EC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969498; 9384377 [H]