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The map label for this gene is trpE2 [H]

Identifier: 172087686

GI number: 172087686

Start: 1137447

End: 1138370

Strand: Reverse

Name: trpE2 [H]

Synonym: VF_2602

Alternate gene names: 172087686

Gene position: 1138370-1137447 (Counterclockwise)

Preceding gene: 172087687

Following gene: 59711640

Centisome position: 39.29

GC content: 37.77

Gene sequence:

>924_bases
ATGCCAATACAATATAATTTAACACAAGATCAACGAATTAGCAGGGAGGCTATAATGCGTTCATCACATTCACAAGATAG
TAAACTTGAACTACTTTGCCTTGATGTCCCATACGTTTCAGATCCAACGGAGCTGTATTCCACATTGTGTGCTGACGGCG
CAATGAGTTTATTACTTGAATCTGCAGAAGTAGATTCAAAAGAAGACCTAAAAAGTCTAATGCTAATTGACGCTGCTGTT
AGAATTCATTGCTTTGGCAAAGACGTAACTTTAGAAGCAATGACAACAAATGGTGAACTATTATTAGCTCAACTTGCTCA
ATGCTTACCATCGACATTGATTCAATCAGTTTCAAATAATCTGTTAACACTTCATTTCCCTGATGCTAATCAAGATCTAG
ATGAAGACAGCCGTCTTCGAGAACTGTCATCATTTGATGCATTACGCTTTATTCAACATCAATTCGACTTATCAGGCTTA
CCTTCAAATGCATTATTCCTTGGCGGTTTATTTGCTTATGACTTAGTAGCCAATTTTGAAAATCTAGGTAATGCTGATTC
AACAAATAAGTGCCCGGATTACCTTTTTTATATTGCAGAGACACTGCTGGTTATTGACCATCAAACTCAAAAGTCCACGT
TACAAGGTACGCTTTTTTCCCAAAATGAAGAAATAAAGCAACAAGTATCAAAACGTTTGTCTTCCATAAAAACATTCTGC
TCTGAATCTCATGATGTTCCATTAGCGCCAGTCTTAACTGAATGTGATGCAGTTCCAAGTGTCTCTGATGATGATTTGCC
AAACGGTTTTAAATTTAAAAGAATTTGTCATCAAAGGAGATGTGTTCCAAGTTGTTCCTTCTCGTCGTTTTACTCTGCCT
TGCCCTGCTCCACTTTCCGCTTACCGCGAACTGAAGATCGGTAA

Upstream 100 bases:

>100_bases
AAAGCACAATTGAGAAATAACGATGAAATAATATACAAACCGCCTTTTAGCCCTCATAAGTTTTAACAAAAGAGTGGCAA
CAACTGTGAAATATGCGACT

Downstream 100 bases:

>100_bases
CCCAAGTCCTTATATGTTCTATCTGCAAGATCGTGATTTCACACTGTTTGGAGCCTCTCCTGAATCAGCTCTTAAATATT
GCAAAGTCAGCAATCAAGTT

Product: component I of anthranilate synthase

Products: NA

Alternate protein names: Anthranilate synthase component I [H]

Number of amino acids: Translated: 307; Mature: 306

Protein sequence:

>307_residues
MPIQYNLTQDQRISREAIMRSSHSQDSKLELLCLDVPYVSDPTELYSTLCADGAMSLLLESAEVDSKEDLKSLMLIDAAV
RIHCFGKDVTLEAMTTNGELLLAQLAQCLPSTLIQSVSNNLLTLHFPDANQDLDEDSRLRELSSFDALRFIQHQFDLSGL
PSNALFLGGLFAYDLVANFENLGNADSTNKCPDYLFYIAETLLVIDHQTQKSTLQGTLFSQNEEIKQQVSKRLSSIKTFC
SESHDVPLAPVLTECDAVPSVSDDDLPNGFKFKRICHQRRCVPSCSFSSFYSALPCSTFRLPRTEDR

Sequences:

>Translated_307_residues
MPIQYNLTQDQRISREAIMRSSHSQDSKLELLCLDVPYVSDPTELYSTLCADGAMSLLLESAEVDSKEDLKSLMLIDAAV
RIHCFGKDVTLEAMTTNGELLLAQLAQCLPSTLIQSVSNNLLTLHFPDANQDLDEDSRLRELSSFDALRFIQHQFDLSGL
PSNALFLGGLFAYDLVANFENLGNADSTNKCPDYLFYIAETLLVIDHQTQKSTLQGTLFSQNEEIKQQVSKRLSSIKTFC
SESHDVPLAPVLTECDAVPSVSDDDLPNGFKFKRICHQRRCVPSCSFSSFYSALPCSTFRLPRTEDR
>Mature_306_residues
PIQYNLTQDQRISREAIMRSSHSQDSKLELLCLDVPYVSDPTELYSTLCADGAMSLLLESAEVDSKEDLKSLMLIDAAVR
IHCFGKDVTLEAMTTNGELLLAQLAQCLPSTLIQSVSNNLLTLHFPDANQDLDEDSRLRELSSFDALRFIQHQFDLSGLP
SNALFLGGLFAYDLVANFENLGNADSTNKCPDYLFYIAETLLVIDHQTQKSTLQGTLFSQNEEIKQQVSKRLSSIKTFCS
ESHDVPLAPVLTECDAVPSVSDDDLPNGFKFKRICHQRRCVPSCSFSSFYSALPCSTFRLPRTEDR

Specific function: Tryptophan biosynthesis; first step. [C]

COG id: COG0147

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component I

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate synthase component I family [H]

Homologues:

Organism=Escherichia coli, GI1787518, Length=231, Percent_Identity=45.4545454545455, Blast_Score=189, Evalue=3e-49,

Paralogues:

None

Copy number: 700 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005801
- InterPro:   IPR019999
- InterPro:   IPR006805
- InterPro:   IPR005257
- InterPro:   IPR015890 [H]

Pfam domain/function: PF04715 Anth_synt_I_N; PF00425 Chorismate_bind [H]

EC number: =4.1.3.27 [H]

Molecular weight: Translated: 34310; Mature: 34179

Theoretical pI: Translated: 4.49; Mature: 4.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
3.6 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPIQYNLTQDQRISREAIMRSSHSQDSKLELLCLDVPYVSDPTELYSTLCADGAMSLLLE
CCEECCCCHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHH
SAEVDSKEDLKSLMLIDAAVRIHCFGKDVTLEAMTTNGELLLAQLAQCLPSTLIQSVSNN
HHCCCCHHHHHHHHHHHHHHEEEEECCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCC
LLTLHFPDANQDLDEDSRLRELSSFDALRFIQHQFDLSGLPSNALFLGGLFAYDLVANFE
EEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
NLGNADSTNKCPDYLFYIAETLLVIDHQTQKSTLQGTLFSQNEEIKQQVSKRLSSIKTFC
HCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
SESHDVPLAPVLTECDAVPSVSDDDLPNGFKFKRICHQRRCVPSCSFSSFYSALPCSTFR
CCCCCCCCHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCC
LPRTEDR
CCCCCCC
>Mature Secondary Structure 
PIQYNLTQDQRISREAIMRSSHSQDSKLELLCLDVPYVSDPTELYSTLCADGAMSLLLE
CEECCCCHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHH
SAEVDSKEDLKSLMLIDAAVRIHCFGKDVTLEAMTTNGELLLAQLAQCLPSTLIQSVSNN
HHCCCCHHHHHHHHHHHHHHEEEEECCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCC
LLTLHFPDANQDLDEDSRLRELSSFDALRFIQHQFDLSGLPSNALFLGGLFAYDLVANFE
EEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
NLGNADSTNKCPDYLFYIAETLLVIDHQTQKSTLQGTLFSQNEEIKQQVSKRLSSIKTFC
HCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
SESHDVPLAPVLTECDAVPSVSDDDLPNGFKFKRICHQRRCVPSCSFSSFYSALPCSTFR
CCCCCCCCHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCC
LPRTEDR
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1773058; 12620739 [H]