Click here to switch to the map view.

The map label for this gene is aroK

Identifier: 170757837

GI number: 170757837

Start: 2023080

End: 2023592

Strand: Reverse

Name: aroK

Synonym: CLD_2738

Alternate gene names: 170757837

Gene position: 2023592-2023080 (Counterclockwise)

Preceding gene: 170754438

Following gene: 170755184

Centisome position: 51.12

GC content: 25.73

Gene sequence:

>513_bases
TTGGAGAATATTGTTTTAATAGGCATGCCTTTAAGTGGAAAAAGCACTTTAGGTAGAGAGCTTAGTAAGATTTTAAAATA
TGATCTTATAGATACGGATACACTTATAGAAGAGATGGAAGATAAAAGTATAAAGGAAATATTTAAAATATATGGGGAAG
ATTACTTTAGAGAAAAGGAATTAGAAATTATAAATAAATTAAAAAAAGAAAGTAATAAAGTTATATCTACAGGTGGAGGA
CTTCCCATATATAATAAAAATATATATGAACTAAAAAATATTGGCTTTACAGTATATCTTAAGGTACCATTGGAAGAGTT
AATTAAAAGAATGGTAAAGAAGGAATATGATACAAGACCCCTTTTAAAAAACAATGATACAAAATTTTTAGAGGAAATGT
ATAAAAATAGGATAGAGATTTATGAAAAGGCTCATACTATAATATGCAATACTAACTACGAAGAAAGCTTAATTAAAATT
GTAAGAGCCTATAAAAAATGGAAGGGTATATAA

Upstream 100 bases:

>100_bases
TAAATCTGAGATTTGTTTAATATTATATAATTATAATAAACTATTGTTACATAAGTATTTTGATTGAAAGTATAATTTTT
TAGTAAAGATGGTGGTGAGT

Downstream 100 bases:

>100_bases
AAGAAAAAAATAACAATATATGTATTTTATGAAAAAATATTTGCAAATAACCATAATATTATTTGCAAATAAAGTGAAGT
TTTGATAAAATATCATTGTT

Product: shikimate kinase

Products: NA

Alternate protein names: SK [H]

Number of amino acids: Translated: 170; Mature: 170

Protein sequence:

>170_residues
MENIVLIGMPLSGKSTLGRELSKILKYDLIDTDTLIEEMEDKSIKEIFKIYGEDYFREKELEIINKLKKESNKVISTGGG
LPIYNKNIYELKNIGFTVYLKVPLEELIKRMVKKEYDTRPLLKNNDTKFLEEMYKNRIEIYEKAHTIICNTNYEESLIKI
VRAYKKWKGI

Sequences:

>Translated_170_residues
MENIVLIGMPLSGKSTLGRELSKILKYDLIDTDTLIEEMEDKSIKEIFKIYGEDYFREKELEIINKLKKESNKVISTGGG
LPIYNKNIYELKNIGFTVYLKVPLEELIKRMVKKEYDTRPLLKNNDTKFLEEMYKNRIEIYEKAHTIICNTNYEESLIKI
VRAYKKWKGI
>Mature_170_residues
MENIVLIGMPLSGKSTLGRELSKILKYDLIDTDTLIEEMEDKSIKEIFKIYGEDYFREKELEIINKLKKESNKVISTGGG
LPIYNKNIYELKNIGFTVYLKVPLEELIKRMVKKEYDTRPLLKNNDTKFLEEMYKNRIEIYEKAHTIICNTNYEESLIKI
VRAYKKWKGI

Specific function: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate [H]

COG id: COG0703

COG function: function code E; Shikimate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate kinase family [H]

Homologues:

Organism=Homo sapiens, GI153792148, Length=174, Percent_Identity=29.8850574712644, Blast_Score=74, Evalue=9e-14,
Organism=Escherichia coli, GI87082255, Length=159, Percent_Identity=30.188679245283, Blast_Score=75, Evalue=2e-15,
Organism=Escherichia coli, GI1786587, Length=165, Percent_Identity=30.3030303030303, Blast_Score=72, Evalue=3e-14,

Paralogues:

None

Copy number: 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000623 [H]

Pfam domain/function: PF01202 SKI [H]

EC number: =2.7.1.71 [H]

Molecular weight: Translated: 20083; Mature: 20083

Theoretical pI: Translated: 9.09; Mature: 9.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENIVLIGMPLSGKSTLGRELSKILKYDLIDTDTLIEEMEDKSIKEIFKIYGEDYFREKE
CCCEEEEEECCCCCHHHHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHCHHHHHHHH
LEIINKLKKESNKVISTGGGLPIYNKNIYELKNIGFTVYLKVPLEELIKRMVKKEYDTRP
HHHHHHHHHHCCCEEECCCCCCCCCCCHHHHHHCCEEEEEECCHHHHHHHHHHHCCCCCC
LLKNNDTKFLEEMYKNRIEIYEKAHTIICNTNYEESLIKIVRAYKKWKGI
CCCCCCHHHHHHHHHHHHHHHHHHCEEEECCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MENIVLIGMPLSGKSTLGRELSKILKYDLIDTDTLIEEMEDKSIKEIFKIYGEDYFREKE
CCCEEEEEECCCCCHHHHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHCHHHHHHHH
LEIINKLKKESNKVISTGGGLPIYNKNIYELKNIGFTVYLKVPLEELIKRMVKKEYDTRP
HHHHHHHHHHCCCEEECCCCCCCCCCCHHHHHHCCEEEEEECCHHHHHHHHHHHCCCCCC
LLKNNDTKFLEEMYKNRIEIYEKAHTIICNTNYEESLIKIVRAYKKWKGI
CCCCCCHHHHHHHHHHHHHHHHHHCEEEECCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA