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The map label for this gene is 170757810

Identifier: 170757810

GI number: 170757810

Start: 887795

End: 889009

Strand: Direct

Name: 170757810

Synonym: CLD_3794

Alternate gene names: NA

Gene position: 887795-889009 (Clockwise)

Preceding gene: 170756107

Following gene: 170754922

Centisome position: 22.43

GC content: 28.4

Gene sequence:

>1215_bases
ATGAAATTGAAAAATTTATTTAAAAGAAGCTTATCTCTTTTATTTTCATTTATAATGATTTTCACATTGGTTTCAGGCTT
AAATGTAAAGGCATTTTTAGGGGATGAACCCAAACAAACTCTTAATGTGGCTTTATATGAATATGTTCCTGATCCTATAC
GTTTTAAAAAAGCAGTTGAAACTGAGTGGAATAAGAAAGAACCTAATATAAGACTTAATTTTGTAGATTGGGATTGTTAT
AGTGAGGATCCACCAAAAGATTTAGATGTATTTGTTTTTGATGCAGTTTATTTATCTCATTTCGTAAAGGAAGGATATTT
ATCAGAAATTCCAGAAAAGGATATAAAAAATAAAGAAGATATTCTACCTTTCGCAATGGAAGGATGTACTATAAAAGGTT
CAGCTTATGCAATTCCTCAAATAATATGTACTAATCTCTTATTTAGTAGAAAAGGAGATTATGACATACAAAAAGTAAAT
TCTGTGTATGATTTATATGACAAGTTAGGAAAGTTCACATCAGAAGATATTATTCTTCCTAACAATAAAGGACTGTTAAT
AGATATGTCTGGAGGAACTAGTAAAGCTTGTATGTATCTAGATTCACTAATTGATACAACTCAAGAGTACACCAAATTTT
GTTCATTACCCAATTTAAATGAATTAAATAAAGATGCAATTGAAAGTTTAGTATTGTTACAATCAATGGCTGGAAAAAGT
CAGGCTAATTACTGGCCAGAAAATAATGATTCATATATTCGAGCTAAATGGTTTATTAACGGAAAAGGGAGAGCTTATAT
AGGTTATACTGAAGCAATGTCCCAAATGAAAGAATTTGCAAATGATATTGATTTTAAGACAATTTCTTTATCAAAAAATT
CTAATATTCCTATTTTTTATGGAGATGTGGTTGGAATAAACTCTTCTATAACGAATTCATATAAGAAAGAAAAAGCAATT
GAGCTTGCTAATATTATTACAGACAAAAACACTATGGTGAAAGCAGTTTCTCCAGATGAAAATAATAAATACCCTCAATA
TTTATTACCTGCTAGAAGAAGTGTATATCATGATTTAGAAAATAAGTATCCTATTTATGGTAGATTATATAAAATAGCTG
ATGATTCTAATAATAAGCTGTTTAGGACTGGCCCTGAAATACGTGAATGGTTAAAACAAGCAAAGAAAATTATTACTGAA
TATTTACAACAATGA

Upstream 100 bases:

>100_bases
TTGGGGGAGCGAAAAGAACAAACCACCCTTTATTATATTTGATGTAGAAAAATAACTGAATTTAGAGATACATTACATGC
ATAATGAAAGGAGTAAACCC

Downstream 100 bases:

>100_bases
TATAATAAATAATAATCATTGAAATTAAAGGTACTTTTATTATTAAAAGTGCCTTTTTGTAGAAGGGAGAAGAGTTTATG
AAGAAAGTACTTAGTATTGC

Product: putative thiaminase I

Products: NA

Alternate protein names: Thiaminase I; Thiamine pyridinylase [H]

Number of amino acids: Translated: 404; Mature: 404

Protein sequence:

>404_residues
MKLKNLFKRSLSLLFSFIMIFTLVSGLNVKAFLGDEPKQTLNVALYEYVPDPIRFKKAVETEWNKKEPNIRLNFVDWDCY
SEDPPKDLDVFVFDAVYLSHFVKEGYLSEIPEKDIKNKEDILPFAMEGCTIKGSAYAIPQIICTNLLFSRKGDYDIQKVN
SVYDLYDKLGKFTSEDIILPNNKGLLIDMSGGTSKACMYLDSLIDTTQEYTKFCSLPNLNELNKDAIESLVLLQSMAGKS
QANYWPENNDSYIRAKWFINGKGRAYIGYTEAMSQMKEFANDIDFKTISLSKNSNIPIFYGDVVGINSSITNSYKKEKAI
ELANIITDKNTMVKAVSPDENNKYPQYLLPARRSVYHDLENKYPIYGRLYKIADDSNNKLFRTGPEIREWLKQAKKIITE
YLQQ

Sequences:

>Translated_404_residues
MKLKNLFKRSLSLLFSFIMIFTLVSGLNVKAFLGDEPKQTLNVALYEYVPDPIRFKKAVETEWNKKEPNIRLNFVDWDCY
SEDPPKDLDVFVFDAVYLSHFVKEGYLSEIPEKDIKNKEDILPFAMEGCTIKGSAYAIPQIICTNLLFSRKGDYDIQKVN
SVYDLYDKLGKFTSEDIILPNNKGLLIDMSGGTSKACMYLDSLIDTTQEYTKFCSLPNLNELNKDAIESLVLLQSMAGKS
QANYWPENNDSYIRAKWFINGKGRAYIGYTEAMSQMKEFANDIDFKTISLSKNSNIPIFYGDVVGINSSITNSYKKEKAI
ELANIITDKNTMVKAVSPDENNKYPQYLLPARRSVYHDLENKYPIYGRLYKIADDSNNKLFRTGPEIREWLKQAKKIITE
YLQQ
>Mature_404_residues
MKLKNLFKRSLSLLFSFIMIFTLVSGLNVKAFLGDEPKQTLNVALYEYVPDPIRFKKAVETEWNKKEPNIRLNFVDWDCY
SEDPPKDLDVFVFDAVYLSHFVKEGYLSEIPEKDIKNKEDILPFAMEGCTIKGSAYAIPQIICTNLLFSRKGDYDIQKVN
SVYDLYDKLGKFTSEDIILPNNKGLLIDMSGGTSKACMYLDSLIDTTQEYTKFCSLPNLNELNKDAIESLVLLQSMAGKS
QANYWPENNDSYIRAKWFINGKGRAYIGYTEAMSQMKEFANDIDFKTISLSKNSNIPIFYGDVVGINSSITNSYKKEKAI
ELANIITDKNTMVKAVSPDENNKYPQYLLPARRSVYHDLENKYPIYGRLYKIADDSNNKLFRTGPEIREWLKQAKKIITE
YLQQ

Specific function: Degrades thiamine by replacing its thiazole moiety with a wide range of nucleophiles [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006059 [H]

Pfam domain/function: PF01547 SBP_bac_1 [H]

EC number: =2.5.1.2 [H]

Molecular weight: Translated: 46446; Mature: 46446

Theoretical pI: Translated: 6.57; Mature: 6.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLKNLFKRSLSLLFSFIMIFTLVSGLNVKAFLGDEPKQTLNVALYEYVPDPIRFKKAVE
CCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHCCCHHHHHHHHH
TEWNKKEPNIRLNFVDWDCYSEDPPKDLDVFVFDAVYLSHFVKEGYLSEIPEKDIKNKED
CCCCCCCCCEEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCC
ILPFAMEGCTIKGSAYAIPQIICTNLLFSRKGDYDIQKVNSVYDLYDKLGKFTSEDIILP
CCCCHHCCCEECCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEE
NNKGLLIDMSGGTSKACMYLDSLIDTTQEYTKFCSLPNLNELNKDAIESLVLLQSMAGKS
CCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCC
QANYWPENNDSYIRAKWFINGKGRAYIGYTEAMSQMKEFANDIDFKTISLSKNSNIPIFY
CCCCCCCCCCCEEEEEEEECCCCCEEEEHHHHHHHHHHHHHHCCEEEEEECCCCCCCEEE
GDVVGINSSITNSYKKEKAIELANIITDKNTMVKAVSPDENNKYPQYLLPARRSVYHDLE
CCEEECCHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHC
NKYPIYGRLYKIADDSNNKLFRTGPEIREWLKQAKKIITEYLQQ
CCCCHHEEEEEEECCCCCCEEECCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKLKNLFKRSLSLLFSFIMIFTLVSGLNVKAFLGDEPKQTLNVALYEYVPDPIRFKKAVE
CCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHCCCHHHHHHHHH
TEWNKKEPNIRLNFVDWDCYSEDPPKDLDVFVFDAVYLSHFVKEGYLSEIPEKDIKNKED
CCCCCCCCCEEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCC
ILPFAMEGCTIKGSAYAIPQIICTNLLFSRKGDYDIQKVNSVYDLYDKLGKFTSEDIILP
CCCCHHCCCEECCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEE
NNKGLLIDMSGGTSKACMYLDSLIDTTQEYTKFCSLPNLNELNKDAIESLVLLQSMAGKS
CCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCC
QANYWPENNDSYIRAKWFINGKGRAYIGYTEAMSQMKEFANDIDFKTISLSKNSNIPIFY
CCCCCCCCCCCEEEEEEEECCCCCEEEEHHHHHHHHHHHHHHCCEEEEEECCCCCCCEEE
GDVVGINSSITNSYKKEKAIELANIITDKNTMVKAVSPDENNKYPQYLLPARRSVYHDLE
CCEEECCHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHC
NKYPIYGRLYKIADDSNNKLFRTGPEIREWLKQAKKIITEYLQQ
CCCCHHEEEEEEECCCCCCEEECCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8631946; 9843405 [H]