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The map label for this gene is helD [H]

Identifier: 170757744

GI number: 170757744

Start: 3147406

End: 3149697

Strand: Reverse

Name: helD [H]

Synonym: CLD_1639

Alternate gene names: 170757744

Gene position: 3149697-3147406 (Counterclockwise)

Preceding gene: 170754746

Following gene: 170755046

Centisome position: 79.57

GC content: 24.69

Gene sequence:

>2292_bases
ATGTCTATTGAAAAAGAAAGTTTTAATATTGAAAAAGAAAAACTAGATGAAACTATCGAATGGATAGAAGAAAAAATAAC
GTCTTTAAAGGAAAGAGAAGAACATATATCTAATAAAATAAATGAAATAAATAAGGAAGTTAAAGGAGCATATAATTATG
AAGTAGAGGCTCTTCAAAATTCTTTACAAATAAATAGAAAGAATTTAAATTCTTATAAATCATCAGTTTCTGTACCTTAT
TTTGCTAGAATTGATTTTAAGGAAAAATTAAAGGATAGTGAGAGTTTTTATATAGGAAAAGTAGGGCTATTAGATGAGGA
AGATAAAGAAGAGATGGTTGTAGATTGGAGATCGCCTATAGCAGATCTTTATTATAGTGGCGTACAAGGTAAAGCTTCCT
ATGAAGCTCCTATTGGAAATATAGAAGGGGAGCTTTTACTTAAGAGAAAGTTTATTATAAAAAATAAAAAGCTAATAGAT
GCCTTTGATGAGGGGATAAATGAAATTATATTAAATTTTAATGGGGAAGATGAACAAAATAGAGAAAAGGCTTTAATAGA
TGAATTCTTAAAAATTAACTTAGAAGAAAATAGAGGAAACAAATTAAAAGATATAGTTTCAACTATACAAAAAGAACAGA
ATGATATTATAAGAGCAGATATGTATAAGCCGCTTATAATACAAGGTTCTGCAGGTTCAGGAAAAACTACTATAGCTCTT
CATAGAATAGCCTATTTATTATATAAATATAAAAATAAAATTACAGGAGAGGATATAATAATACTAGCTCCCAATAAATT
GTTTTTAGATTATATATCTGAAGTTCTCCCTAATTTAGGAGTTGATAAAGTAAAACAAAGCACTTTTAATAAACTTTCTA
AAGAAATATTGAATTTCAATTATGAAATAATAGATAAGGATAAAAAATTATCTAAAATTATAGAAAATAAAAATAGAAAA
GAAAACAAATTTATAACTAATAGTAATAAATTAAAAGGTTCTTTAGTTTATAAAAAAATGCTAGATAGATATATAAAATA
TTTGGAATTAAATGATATGTTCATAGACGATATAAAAATAGATGGTTATGTAATATTTACTTCTAGAGAAATAATAAGAC
TTTATAAAAATGATTTAAAGCATCTTCCGCTAAATAAAAGAAAAATTGAAATAGGAAGATATTTAAAGAACAAAATAGAG
ACAAAAATTCAAGATGTATGGAATGATATAGATAAAGATTATATCTTAAAAATAAGAGAAGTAAGAGCAAAATACGAAGG
TGAAGAAGAAAGAACTAATATTATAAAATTATATGAAGAAAGAGACAATAAAAAGGAAAAAATAAAATTAGAAGCAGAAG
AAGTACTAAATAAAACTATTAGAGAATGGCTTATTGATGATGTAGTAGATGTATATAGAGATATGTATATTGATGAAGAA
AACTTAATTTATGCCACATCAGGCATAATACCAGAAGTTTTAGTTAATTATATAAAAAATAAAATAGAAAAAGAAATAGA
GAATGAAAAAATAGATGAAGAAGATCTAGCAGCACTTTTATACTTAAAAATAAAGATAGATGGAGTAGATAATTATAAAT
TTGCCCATATGGTTATAGATGAGGCTCAAGATTATAGTCCCTTAGAATTATATGTATTAAAATTGCTTTCAAAAGCTAGA
GGATATACTATAGTTGGTGATTTAGGTCAAAGTATATATTACTATAAAGGCATAGAAAACTGGGAAAAATTAATTAAAGA
AGTATATGAGGAAGGAGAATATATTCCACTAAAACAAAGTTATCGTTCTACAGTGGAAATAGTAGATTTTGCAAATAAAG
TACTAAGAAAACAAAAAAATAATTTAGAACCAGCTAAAGCAGTGTTAAGGCATGGAAAACATCCAAAAAAGATTCAGTAT
AAGGACGAAAAAGATTTCTATGAAAAATTAAATAGTGTTATTGAAACCATAGAAGAAAAGAAAGATAAAACTATAGCAAT
AATCTGCAAAGATTATGAGCAGTGTGAGAGTTTAAAAGAGTCTTTACATTTAAAAGAAGAAAAACAATGGGAAATAGTAA
CTAAAGATACTGAAATGTTACCTAAGAGAATAATTATACCATCATACATAACAAAAGGTTTAGAATTTGATTGTTCTATA
ATTTATGATTGTAGTGATGAAAATTATAGAGAAACTGAATTAGACAAAAAGATTTTATATGTAGTTCTAACAAGAGCATT
GCATGAAGAGTATATTTTTTATAAAGATAATATAACTAAGTTATTAATATAA

Upstream 100 bases:

>100_bases
TCTAGAGACGTCATAAAATAGGAAAGTTAAATAAAGTGAAAAAATTAGTGGTAAATATGTTAAAATATTAAGGGCGTCTT
TATATTTAGGGAGGTATATT

Downstream 100 bases:

>100_bases
GAGAAAATAAAATGAATTGTAAAATTATTATATTTAAGAAAATGATGATAATAGTTTAACAATATTTTGTATATTTCTAA
GCTTTTAAAAGCTAAAAATT

Product: putative helicase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 763; Mature: 762

Protein sequence:

>763_residues
MSIEKESFNIEKEKLDETIEWIEEKITSLKEREEHISNKINEINKEVKGAYNYEVEALQNSLQINRKNLNSYKSSVSVPY
FARIDFKEKLKDSESFYIGKVGLLDEEDKEEMVVDWRSPIADLYYSGVQGKASYEAPIGNIEGELLLKRKFIIKNKKLID
AFDEGINEIILNFNGEDEQNREKALIDEFLKINLEENRGNKLKDIVSTIQKEQNDIIRADMYKPLIIQGSAGSGKTTIAL
HRIAYLLYKYKNKITGEDIIILAPNKLFLDYISEVLPNLGVDKVKQSTFNKLSKEILNFNYEIIDKDKKLSKIIENKNRK
ENKFITNSNKLKGSLVYKKMLDRYIKYLELNDMFIDDIKIDGYVIFTSREIIRLYKNDLKHLPLNKRKIEIGRYLKNKIE
TKIQDVWNDIDKDYILKIREVRAKYEGEEERTNIIKLYEERDNKKEKIKLEAEEVLNKTIREWLIDDVVDVYRDMYIDEE
NLIYATSGIIPEVLVNYIKNKIEKEIENEKIDEEDLAALLYLKIKIDGVDNYKFAHMVIDEAQDYSPLELYVLKLLSKAR
GYTIVGDLGQSIYYYKGIENWEKLIKEVYEEGEYIPLKQSYRSTVEIVDFANKVLRKQKNNLEPAKAVLRHGKHPKKIQY
KDEKDFYEKLNSVIETIEEKKDKTIAIICKDYEQCESLKESLHLKEEKQWEIVTKDTEMLPKRIIIPSYITKGLEFDCSI
IYDCSDENYRETELDKKILYVVLTRALHEEYIFYKDNITKLLI

Sequences:

>Translated_763_residues
MSIEKESFNIEKEKLDETIEWIEEKITSLKEREEHISNKINEINKEVKGAYNYEVEALQNSLQINRKNLNSYKSSVSVPY
FARIDFKEKLKDSESFYIGKVGLLDEEDKEEMVVDWRSPIADLYYSGVQGKASYEAPIGNIEGELLLKRKFIIKNKKLID
AFDEGINEIILNFNGEDEQNREKALIDEFLKINLEENRGNKLKDIVSTIQKEQNDIIRADMYKPLIIQGSAGSGKTTIAL
HRIAYLLYKYKNKITGEDIIILAPNKLFLDYISEVLPNLGVDKVKQSTFNKLSKEILNFNYEIIDKDKKLSKIIENKNRK
ENKFITNSNKLKGSLVYKKMLDRYIKYLELNDMFIDDIKIDGYVIFTSREIIRLYKNDLKHLPLNKRKIEIGRYLKNKIE
TKIQDVWNDIDKDYILKIREVRAKYEGEEERTNIIKLYEERDNKKEKIKLEAEEVLNKTIREWLIDDVVDVYRDMYIDEE
NLIYATSGIIPEVLVNYIKNKIEKEIENEKIDEEDLAALLYLKIKIDGVDNYKFAHMVIDEAQDYSPLELYVLKLLSKAR
GYTIVGDLGQSIYYYKGIENWEKLIKEVYEEGEYIPLKQSYRSTVEIVDFANKVLRKQKNNLEPAKAVLRHGKHPKKIQY
KDEKDFYEKLNSVIETIEEKKDKTIAIICKDYEQCESLKESLHLKEEKQWEIVTKDTEMLPKRIIIPSYITKGLEFDCSI
IYDCSDENYRETELDKKILYVVLTRALHEEYIFYKDNITKLLI
>Mature_762_residues
SIEKESFNIEKEKLDETIEWIEEKITSLKEREEHISNKINEINKEVKGAYNYEVEALQNSLQINRKNLNSYKSSVSVPYF
ARIDFKEKLKDSESFYIGKVGLLDEEDKEEMVVDWRSPIADLYYSGVQGKASYEAPIGNIEGELLLKRKFIIKNKKLIDA
FDEGINEIILNFNGEDEQNREKALIDEFLKINLEENRGNKLKDIVSTIQKEQNDIIRADMYKPLIIQGSAGSGKTTIALH
RIAYLLYKYKNKITGEDIIILAPNKLFLDYISEVLPNLGVDKVKQSTFNKLSKEILNFNYEIIDKDKKLSKIIENKNRKE
NKFITNSNKLKGSLVYKKMLDRYIKYLELNDMFIDDIKIDGYVIFTSREIIRLYKNDLKHLPLNKRKIEIGRYLKNKIET
KIQDVWNDIDKDYILKIREVRAKYEGEEERTNIIKLYEERDNKKEKIKLEAEEVLNKTIREWLIDDVVDVYRDMYIDEEN
LIYATSGIIPEVLVNYIKNKIEKEIENEKIDEEDLAALLYLKIKIDGVDNYKFAHMVIDEAQDYSPLELYVLKLLSKARG
YTIVGDLGQSIYYYKGIENWEKLIKEVYEEGEYIPLKQSYRSTVEIVDFANKVLRKQKNNLEPAKAVLRHGKHPKKIQYK
DEKDFYEKLNSVIETIEEKKDKTIAIICKDYEQCESLKESLHLKEEKQWEIVTKDTEMLPKRIIIPSYITKGLEFDCSII
YDCSDENYRETELDKKILYVVLTRALHEEYIFYKDNITKLLI

Specific function: Catalyzes the unwinding of duplex DNA in the 3' to 5' direction; this reaction is dependent on the hydrolysis of ATP [H]

COG id: COG3973

COG function: function code R; Superfamily I DNA and RNA helicases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 uvrD-like helicase ATP-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: 3000 [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000212
- InterPro:   IPR014016 [H]

Pfam domain/function: PF00580 UvrD-helicase [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 90088; Mature: 89956

Theoretical pI: Translated: 5.30; Mature: 5.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIEKESFNIEKEKLDETIEWIEEKITSLKEREEHISNKINEINKEVKGAYNYEVEALQN
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHH
SLQINRKNLNSYKSSVSVPYFARIDFKEKLKDSESFYIGKVGLLDEEDKEEMVVDWRSPI
HHHHHHHHHHHHHHCCCCCEEEECCHHHHCCCCCCEEEEEECCCCCCCCHHHHHHHHHHH
ADLYYSGVQGKASYEAPIGNIEGELLLKRKFIIKNKKLIDAFDEGINEIILNFNGEDEQN
HHHHHCCCCCCCCCCCCCCCCCCHHEEHHHHHHCCCHHHHHHHCCHHHEEEECCCCCCCH
REKALIDEFLKINLEENRGNKLKDIVSTIQKEQNDIIRADMYKPLIIQGSAGSGKTTIAL
HHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCHHHCCCCEEEECCCCCCCHHHHH
HRIAYLLYKYKNKITGEDIIILAPNKLFLDYISEVLPNLGVDKVKQSTFNKLSKEILNFN
HHHHHHHHHHHCCCCCCCEEEECCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCC
YEIIDKDKKLSKIIENKNRKENKFITNSNKLKGSLVYKKMLDRYIKYLELNDMFIDDIKI
CEEECCHHHHHHHHHCCCCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHCCEEEEEEEE
DGYVIFTSREIIRLYKNDLKHLPLNKRKIEIGRYLKNKIETKIQDVWNDIDKDYILKIRE
CCEEEECHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
VRAKYEGEEERTNIIKLYEERDNKKEKIKLEAEEVLNKTIREWLIDDVVDVYRDMYIDEE
HHHHHCCCHHHHHHHHHHHHHCCCHHHEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
NLIYATSGIIPEVLVNYIKNKIEKEIENEKIDEEDLAALLYLKIKIDGVDNYKFAHMVID
CEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHEEEEEEEEECCCCCCEEHHHHHH
EAQDYSPLELYVLKLLSKARGYTIVGDLGQSIYYYKGIENWEKLIKEVYEEGEYIPLKQS
CCCCCCHHHHHHHHHHHHHCCEEEEECCCCCEEEECCHHHHHHHHHHHHHCCCEECCHHH
YRSTVEIVDFANKVLRKQKNNLEPAKAVLRHGKHPKKIQYKDEKDFYEKLNSVIETIEEK
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHC
KDKTIAIICKDYEQCESLKESLHLKEEKQWEIVTKDTEMLPKRIIIPSYITKGLEFDCSI
CCCEEEEEECCHHHHHHHHHHHCCCCCCCCEEEECCHHHHHHHCCCHHHHHCCCCCCEEE
IYDCSDENYRETELDKKILYVVLTRALHEEYIFYKDNITKLLI
EEECCCCCCCHHHHHHHHHHHHHHHHHHHHHEEEECCCHHHCC
>Mature Secondary Structure 
SIEKESFNIEKEKLDETIEWIEEKITSLKEREEHISNKINEINKEVKGAYNYEVEALQN
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHH
SLQINRKNLNSYKSSVSVPYFARIDFKEKLKDSESFYIGKVGLLDEEDKEEMVVDWRSPI
HHHHHHHHHHHHHHCCCCCEEEECCHHHHCCCCCCEEEEEECCCCCCCCHHHHHHHHHHH
ADLYYSGVQGKASYEAPIGNIEGELLLKRKFIIKNKKLIDAFDEGINEIILNFNGEDEQN
HHHHHCCCCCCCCCCCCCCCCCCHHEEHHHHHHCCCHHHHHHHCCHHHEEEECCCCCCCH
REKALIDEFLKINLEENRGNKLKDIVSTIQKEQNDIIRADMYKPLIIQGSAGSGKTTIAL
HHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCHHHCCCCEEEECCCCCCCHHHHH
HRIAYLLYKYKNKITGEDIIILAPNKLFLDYISEVLPNLGVDKVKQSTFNKLSKEILNFN
HHHHHHHHHHHCCCCCCCEEEECCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCC
YEIIDKDKKLSKIIENKNRKENKFITNSNKLKGSLVYKKMLDRYIKYLELNDMFIDDIKI
CEEECCHHHHHHHHHCCCCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHCCEEEEEEEE
DGYVIFTSREIIRLYKNDLKHLPLNKRKIEIGRYLKNKIETKIQDVWNDIDKDYILKIRE
CCEEEECHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
VRAKYEGEEERTNIIKLYEERDNKKEKIKLEAEEVLNKTIREWLIDDVVDVYRDMYIDEE
HHHHHCCCHHHHHHHHHHHHHCCCHHHEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
NLIYATSGIIPEVLVNYIKNKIEKEIENEKIDEEDLAALLYLKIKIDGVDNYKFAHMVID
CEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHEEEEEEEEECCCCCCEEHHHHHH
EAQDYSPLELYVLKLLSKARGYTIVGDLGQSIYYYKGIENWEKLIKEVYEEGEYIPLKQS
CCCCCCHHHHHHHHHHHHHCCEEEEECCCCCEEEECCHHHHHHHHHHHHHCCCEECCHHH
YRSTVEIVDFANKVLRKQKNNLEPAKAVLRHGKHPKKIQYKDEKDFYEKLNSVIETIEEK
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHC
KDKTIAIICKDYEQCESLKESLHLKEEKQWEIVTKDTEMLPKRIIIPSYITKGLEFDCSI
CCCEEEEEECCHHHHHHHHHHHCCCCCCCCEEEECCHHHHHHHCCCHHHHHCCCCCCEEE
IYDCSDENYRETELDKKILYVVLTRALHEEYIFYKDNITKLLI
EEECCCCCCCHHHHHHHHHHHHHHHHHHHHHEEEECCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]