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The map label for this gene is map

Identifier: 170757409

GI number: 170757409

Start: 3766631

End: 3767380

Strand: Reverse

Name: map

Synonym: CLD_1046

Alternate gene names: 170757409

Gene position: 3767380-3766631 (Counterclockwise)

Preceding gene: 170755733

Following gene: 170754750

Centisome position: 95.18

GC content: 33.07

Gene sequence:

>750_bases
ATGATAACAATAAAAACCGATTCTGAAATAGAATACATGGTAAAAGCAGGAAAAGTTGTTGCTGAAGCCTTAGACACTTT
AGAAAAACATGTAAAGCCAGGAATAAGCACTGGAGAGTTAGATAGAATCGCAGAAGAGATTATATTAGGCAGAAATGCTA
AACCATCTTTTAAAGGATATTATGGTTTCCCAGCTTCTATATGTGCATCTGTGAATAATGAAGTAGTTCATGGAATACCA
AATAAAGATAGAATTTTAAATGAAGGAGACATAATTAGTATAGATTGTGGAGCTATTTTAAATGGATATCAGGGCGATGC
AGCAAGAACATTTCCAGTAGGAAATGTTTCAGAGGAAGCTGCTAAGCTAATAGAGGTTACAAAAAATAGTTTTTTCAAAG
GTATAGAAAAAGCTAAAGTTGGCAATAGATTAACTGATATATCTGCAGCTATTCAAGAATATGTTGAAAGTTATGGACTT
TCTATTGTAAGGGATTATGTAGGTCATGGCATAGGAAAAAACATGCATGAAGATCCAGAAATTCCTAACTTTGGTAGACC
AGGAAGGGGACCTAAATTATCAAAAGGAATGTGTTTAGCTATTGAGCCTATGGTTAATATAGGAGACTTCAATGTAAAAG
TTGAACCAAATAAATGGACTGTAGTTACTGTAGATGGTAGTTTATCTGCTCATTATGAAAATACTGTAGCTATACTAGAT
GATGGACCTAAAATAACCACTTTAATTTAA

Upstream 100 bases:

>100_bases
ATTATTATAAAGACAATGGTATAATCTCAGAGGTTAATGGGACTGAATCAATTAATGAGGTATTTGGAAATATTTCGAAT
ATCTTAGGGAGAGATAAATA

Downstream 100 bases:

>100_bases
TAGAGGTGAATATATTGGCTAAAGAGTGCCAGATTGGTAGATTGGTTTTATCGAAAGCAGGTAGAGATAAAGATAATAGT
TTCATTATAATAGATATACT

Product: methionine aminopeptidase, type I

Products: NA

Alternate protein names: MAP; Peptidase M [H]

Number of amino acids: Translated: 249; Mature: 249

Protein sequence:

>249_residues
MITIKTDSEIEYMVKAGKVVAEALDTLEKHVKPGISTGELDRIAEEIILGRNAKPSFKGYYGFPASICASVNNEVVHGIP
NKDRILNEGDIISIDCGAILNGYQGDAARTFPVGNVSEEAAKLIEVTKNSFFKGIEKAKVGNRLTDISAAIQEYVESYGL
SIVRDYVGHGIGKNMHEDPEIPNFGRPGRGPKLSKGMCLAIEPMVNIGDFNVKVEPNKWTVVTVDGSLSAHYENTVAILD
DGPKITTLI

Sequences:

>Translated_249_residues
MITIKTDSEIEYMVKAGKVVAEALDTLEKHVKPGISTGELDRIAEEIILGRNAKPSFKGYYGFPASICASVNNEVVHGIP
NKDRILNEGDIISIDCGAILNGYQGDAARTFPVGNVSEEAAKLIEVTKNSFFKGIEKAKVGNRLTDISAAIQEYVESYGL
SIVRDYVGHGIGKNMHEDPEIPNFGRPGRGPKLSKGMCLAIEPMVNIGDFNVKVEPNKWTVVTVDGSLSAHYENTVAILD
DGPKITTLI
>Mature_249_residues
MITIKTDSEIEYMVKAGKVVAEALDTLEKHVKPGISTGELDRIAEEIILGRNAKPSFKGYYGFPASICASVNNEVVHGIP
NKDRILNEGDIISIDCGAILNGYQGDAARTFPVGNVSEEAAKLIEVTKNSFFKGIEKAKVGNRLTDISAAIQEYVESYGL
SIVRDYVGHGIGKNMHEDPEIPNFGRPGRGPKLSKGMCLAIEPMVNIGDFNVKVEPNKWTVVTVDGSLSAHYENTVAILD
DGPKITTLI

Specific function: Removes the amino-terminal methionine from nascent proteins [H]

COG id: COG0024

COG function: function code J; Methionine aminopeptidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24A family [H]

Homologues:

Organism=Homo sapiens, GI164420681, Length=247, Percent_Identity=36.8421052631579, Blast_Score=177, Evalue=6e-45,
Organism=Homo sapiens, GI40385867, Length=246, Percent_Identity=37.3983739837398, Blast_Score=162, Evalue=2e-40,
Organism=Escherichia coli, GI1786364, Length=248, Percent_Identity=42.741935483871, Blast_Score=215, Evalue=3e-57,
Organism=Caenorhabditis elegans, GI71996291, Length=248, Percent_Identity=37.0967741935484, Blast_Score=170, Evalue=7e-43,
Organism=Saccharomyces cerevisiae, GI6323273, Length=248, Percent_Identity=37.5, Blast_Score=171, Evalue=1e-43,
Organism=Drosophila melanogaster, GI21355531, Length=246, Percent_Identity=41.0569105691057, Blast_Score=194, Evalue=4e-50,
Organism=Drosophila melanogaster, GI24583427, Length=246, Percent_Identity=38.6178861788618, Blast_Score=170, Evalue=7e-43,

Paralogues:

None

Copy number: 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR002467 [H]

Pfam domain/function: PF00557 Peptidase_M24 [H]

EC number: =3.4.11.18 [H]

Molecular weight: Translated: 26949; Mature: 26949

Theoretical pI: Translated: 5.19; Mature: 5.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITIKTDSEIEYMVKAGKVVAEALDTLEKHVKPGISTGELDRIAEEIILGRNAKPSFKGY
CEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCCCC
YGFPASICASVNNEVVHGIPNKDRILNEGDIISIDCGAILNGYQGDAARTFPVGNVSEEA
CCCHHHHHHHCCCCEEECCCCCCCCCCCCCEEEEEHHHHHCCCCCCCCEECCCCCCHHHH
AKLIEVTKNSFFKGIEKAKVGNRLTDISAAIQEYVESYGLSIVRDYVGHGIGKNMHEDPE
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
IPNFGRPGRGPKLSKGMCLAIEPMVNIGDFNVKVEPNKWTVVTVDGSLSAHYENTVAILD
CCCCCCCCCCCCCCCCEEEEEECCCCCCCEEEEECCCCEEEEEECCCCEECCCCEEEEEE
DGPKITTLI
CCCEEEEEC
>Mature Secondary Structure
MITIKTDSEIEYMVKAGKVVAEALDTLEKHVKPGISTGELDRIAEEIILGRNAKPSFKGY
CEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCCCC
YGFPASICASVNNEVVHGIPNKDRILNEGDIISIDCGAILNGYQGDAARTFPVGNVSEEA
CCCHHHHHHHCCCCEEECCCCCCCCCCCCCEEEEEHHHHHCCCCCCCCEECCCCCCHHHH
AKLIEVTKNSFFKGIEKAKVGNRLTDISAAIQEYVESYGLSIVRDYVGHGIGKNMHEDPE
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
IPNFGRPGRGPKLSKGMCLAIEPMVNIGDFNVKVEPNKWTVVTVDGSLSAHYENTVAILD
CCCCCCCCCCCCCCCCEEEEEECCCCCCCEEEEECCCCEEEEEECCCCEECCCCEEEEEE
DGPKITTLI
CCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11466286 [H]