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The map label for this gene is lytC [H]

Identifier: 170757215

GI number: 170757215

Start: 469844

End: 471913

Strand: Direct

Name: lytC [H]

Synonym: CLD_0372

Alternate gene names: 170757215

Gene position: 469844-471913 (Clockwise)

Preceding gene: 170755070

Following gene: 170756257

Centisome position: 11.87

GC content: 27.54

Gene sequence:

>2070_bases
ATGGTAAAATCTAAAGAAAAAAACAAAATATTTTTTACCTTATTAGCCATTACTTTAATTTTTATTGTTAATTCTAATAA
GGTAAAAGCTAATGATGAGATTAATTTTAGAAGATTAGATGGTAAGGAACGATATGAGACCTCAGCTTCTATATGTAGTG
GTGGATGGGACACATCAGAGTATGCTGTTCTAGCAAGTGGAGAAGGATTTGCAGATGCTTTAAGTGCAGCTCCATTAGCT
AAGAAATATGATGCACCTATAATTTTAACAGGAAAAAATAAGTTGAATGATAATGCTAAGGATCAGCTAAAAAAATTAGA
TACTAAAGAGGTAATAATAGTTGGAGGACCTGGGTCAATTTCAGAAGATATAGTAACAGAACTAAAAGATCTAGGAATAA
AGGTTAATAGAATATATGGTGAAGATAGATATAAAACTAGTTTAAAAATTGCAAAGGAAATAGGAGTAAAAAATGGAATA
GTAGTTACAAATGGTCTAGGATTTGCTGATGCATTAGGTATGGCACCTATAGCAGCTAGTAAACAGATGCCTATTTTGTT
AACTCCTAGTGACAAATTAACAAGTGATACAATGGAGTTTTTAAAGAAAAGTTCTTATAATAAAAGCTATGTTTTAGGAG
GAACTGCTACAGTTAGTGATTATATAAAAAATTCATTAAAAAATCCAACTAGATTAAGTGGAGCTGATAGATATAAAACT
AATATAGCTATATTAAATCATTTTAAAGGGGATTTAAACCTGGATGAAGTATATATTGCTTCAGGAGATGGATATGCAGA
TGCTTTGTCTGGTTCAGTATTAGCTAGTAAAAATAAATCTCCAATAATATTAATAAATGATAATTTAAATAAAAGTACAA
AAGATTTTGTAAGTACTAATAAGTATAACTTTAAAAATGTAACAATATTTGGAGGAGAAGCAGTAGTAAAGGAGCCTACT
ATAAGCAGTTTGTTTGGAGCATTTAGATCTGGTGAAACAAGATCAGATACCAAAGAAGTTGTTGCAGAAAAATGGGATAG
ATCCTATCTTAAAGATTATCATATTGATTTACCAGAGGGTGGTAAATTGGATATAGAGTATGATATTAACAATTTTACTC
GTTTTGATTTAATTGTTTTAGATATAAAGAATAATGAAATCATAAAAAAATCCTATAATTATTTGAAGAACAATAAGAGC
ATTCATGATAACTATAATGATATAAGATTGCCTAAAGGAAAATATATCGTTAGGGTACATGCATTTAATATGGATGGAAC
TTACACAATTAAAGCAAAATATACTCAAGAGGGAGAAGGCTTTGAAAAGGAAAGTAATAATGATATAAAAACTGCAAATG
TTATAGAACCTAATAAAAGTATTATAGGAAGTATTCATAGCTATAATGATGTAGATTATTATAAATTTACATTAAATGAA
AAAGGAAGTTTAAAAATAAATTTAAAACATAATCAATATGGTAGATATGGATTTAAGGTTAGTTTGGTAGATGAAAATAA
TAAATCAATAGCAGAATTTATTAGTGGAGGAGAAGATATAAATTCTTATAGTAATAAATTAAGACTTTCTAAAGGAACTT
ATTTTGTAAGAATAGAGTGTGAAAAATGGAATGATGAACCCTTACAGTATGAGCTAAATTTAGTTTATGATATTGAAGGT
GAAAATTATGAGTCAGAGCCAAATGATTATATACAAGATGCTAATTATATAAAGTGCGATAAAGAGTATATAGGAAATAT
ACAGTCAATAAGTGATAGAGATTATTATAAAATAAATTTAAATTCAGATTCTAAAATAACAATTAACTTTAAACATGATG
AAGGATATGGAAAGTGGACTATTTATTTATGTGATAAGGACAATAAACCAATAAAACGATTTAAGTCCTATGGTTATGAG
ATTAGTAAGGACTTTGATCCAGTAGAACTAGAAGCAGGAGAATATTATGTGTCAGTAGAAGGGATAGATAGTATAGATTA
TACTATAAATGTAAAGCGAGAAGCACCAGATAAATCTAATAATGAGAATAAAAAAGTAAAAAGAAGATAA

Upstream 100 bases:

>100_bases
TATTTACACTTTATTCACAATGATTGGGTGAATTTTTATCCATGATTATGATAATATAGTATGATGGACCATTATATGAA
ATATTTAGGGGGTACGGGAT

Downstream 100 bases:

>100_bases
ATCATATCAAAAGACTATTAAATGAAATAATTCATTTAATAGTCTTTTATTTTCATGTAATTAATATTTATCATAGATAA
TAAGTAAGGAATATGAATTT

Product: amidase domain-containing protein

Products: NA

Alternate protein names: Cell wall hydrolase; Cell wall-associated polypeptide CWBP49; CWBP49; Major autolysin [H]

Number of amino acids: Translated: 689; Mature: 689

Protein sequence:

>689_residues
MVKSKEKNKIFFTLLAITLIFIVNSNKVKANDEINFRRLDGKERYETSASICSGGWDTSEYAVLASGEGFADALSAAPLA
KKYDAPIILTGKNKLNDNAKDQLKKLDTKEVIIVGGPGSISEDIVTELKDLGIKVNRIYGEDRYKTSLKIAKEIGVKNGI
VVTNGLGFADALGMAPIAASKQMPILLTPSDKLTSDTMEFLKKSSYNKSYVLGGTATVSDYIKNSLKNPTRLSGADRYKT
NIAILNHFKGDLNLDEVYIASGDGYADALSGSVLASKNKSPIILINDNLNKSTKDFVSTNKYNFKNVTIFGGEAVVKEPT
ISSLFGAFRSGETRSDTKEVVAEKWDRSYLKDYHIDLPEGGKLDIEYDINNFTRFDLIVLDIKNNEIIKKSYNYLKNNKS
IHDNYNDIRLPKGKYIVRVHAFNMDGTYTIKAKYTQEGEGFEKESNNDIKTANVIEPNKSIIGSIHSYNDVDYYKFTLNE
KGSLKINLKHNQYGRYGFKVSLVDENNKSIAEFISGGEDINSYSNKLRLSKGTYFVRIECEKWNDEPLQYELNLVYDIEG
ENYESEPNDYIQDANYIKCDKEYIGNIQSISDRDYYKINLNSDSKITINFKHDEGYGKWTIYLCDKDNKPIKRFKSYGYE
ISKDFDPVELEAGEYYVSVEGIDSIDYTINVKREAPDKSNNENKKVKRR

Sequences:

>Translated_689_residues
MVKSKEKNKIFFTLLAITLIFIVNSNKVKANDEINFRRLDGKERYETSASICSGGWDTSEYAVLASGEGFADALSAAPLA
KKYDAPIILTGKNKLNDNAKDQLKKLDTKEVIIVGGPGSISEDIVTELKDLGIKVNRIYGEDRYKTSLKIAKEIGVKNGI
VVTNGLGFADALGMAPIAASKQMPILLTPSDKLTSDTMEFLKKSSYNKSYVLGGTATVSDYIKNSLKNPTRLSGADRYKT
NIAILNHFKGDLNLDEVYIASGDGYADALSGSVLASKNKSPIILINDNLNKSTKDFVSTNKYNFKNVTIFGGEAVVKEPT
ISSLFGAFRSGETRSDTKEVVAEKWDRSYLKDYHIDLPEGGKLDIEYDINNFTRFDLIVLDIKNNEIIKKSYNYLKNNKS
IHDNYNDIRLPKGKYIVRVHAFNMDGTYTIKAKYTQEGEGFEKESNNDIKTANVIEPNKSIIGSIHSYNDVDYYKFTLNE
KGSLKINLKHNQYGRYGFKVSLVDENNKSIAEFISGGEDINSYSNKLRLSKGTYFVRIECEKWNDEPLQYELNLVYDIEG
ENYESEPNDYIQDANYIKCDKEYIGNIQSISDRDYYKINLNSDSKITINFKHDEGYGKWTIYLCDKDNKPIKRFKSYGYE
ISKDFDPVELEAGEYYVSVEGIDSIDYTINVKREAPDKSNNENKKVKRR
>Mature_689_residues
MVKSKEKNKIFFTLLAITLIFIVNSNKVKANDEINFRRLDGKERYETSASICSGGWDTSEYAVLASGEGFADALSAAPLA
KKYDAPIILTGKNKLNDNAKDQLKKLDTKEVIIVGGPGSISEDIVTELKDLGIKVNRIYGEDRYKTSLKIAKEIGVKNGI
VVTNGLGFADALGMAPIAASKQMPILLTPSDKLTSDTMEFLKKSSYNKSYVLGGTATVSDYIKNSLKNPTRLSGADRYKT
NIAILNHFKGDLNLDEVYIASGDGYADALSGSVLASKNKSPIILINDNLNKSTKDFVSTNKYNFKNVTIFGGEAVVKEPT
ISSLFGAFRSGETRSDTKEVVAEKWDRSYLKDYHIDLPEGGKLDIEYDINNFTRFDLIVLDIKNNEIIKKSYNYLKNNKS
IHDNYNDIRLPKGKYIVRVHAFNMDGTYTIKAKYTQEGEGFEKESNNDIKTANVIEPNKSIIGSIHSYNDVDYYKFTLNE
KGSLKINLKHNQYGRYGFKVSLVDENNKSIAEFISGGEDINSYSNKLRLSKGTYFVRIECEKWNDEPLQYELNLVYDIEG
ENYESEPNDYIQDANYIKCDKEYIGNIQSISDRDYYKINLNSDSKITINFKHDEGYGKWTIYLCDKDNKPIKRFKSYGYE
ISKDFDPVELEAGEYYVSVEGIDSIDYTINVKREAPDKSNNENKKVKRR

Specific function: Autolysins are involved in some important biological processes such as cell separation, cell-wall turnover, competence for genetic transformation, formation of the flagella - in particular of its basal body - and sporulation. Has a high affinity for teich

COG id: COG2247

COG function: function code M; Putative cell wall-binding domain

Gene ontology:

Cell location: Secreted, cell wall [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the N-acetylmuramoyl-L-alanine amidase 3 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007253
- InterPro:   IPR002508 [H]

Pfam domain/function: PF01520 Amidase_3; PF04122 CW_binding_2 [H]

EC number: =3.5.1.28 [H]

Molecular weight: Translated: 77859; Mature: 77859

Theoretical pI: Translated: 6.89; Mature: 6.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKSKEKNKIFFTLLAITLIFIVNSNKVKANDEINFRRLDGKERYETSASICSGGWDTSE
CCCCCCCCEEEHHHHHHHHEEEECCCEEECCCCEEEEECCCHHHHHCCHHHHCCCCCCCC
YAVLASGEGFADALSAAPLAKKYDAPIILTGKNKLNDNAKDQLKKLDTKEVIIVGGPGSI
EEEEECCCCHHHHHHCCCCHHHCCCCEEEECCCCCCCCHHHHHHHCCCCCEEEECCCCCC
SEDIVTELKDLGIKVNRIYGEDRYKTSLKIAKEIGVKNGIVVTNGLGFADALGMAPIAAS
HHHHHHHHHHCCEEEEEEECCCHHHHHHHHHHHCCCCCCEEEECCCCHHHHHCCCCCCCC
KQMPILLTPSDKLTSDTMEFLKKSSYNKSYVLGGTATVSDYIKNSLKNPTRLSGADRYKT
CCCCEEECCCCCCCHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHCCCCCCCCCCCHHEE
NIAILNHFKGDLNLDEVYIASGDGYADALSGSVLASKNKSPIILINDNLNKSTKDFVSTN
EEEEEEECCCCCCCCEEEEECCCCCHHHCCCCEEECCCCCCEEEECCCCCCCCHHHHCCC
KYNFKNVTIFGGEAVVKEPTISSLFGAFRSGETRSDTKEVVAEKWDRSYLKDYHIDLPEG
CCCCEEEEEECCCEEEECCCHHHHHHHHHCCCCCCHHHHHHHHHHCHHHHHHEEEECCCC
GKLDIEYDINNFTRFDLIVLDIKNNEIIKKSYNYLKNNKSIHDNYNDIRLPKGKYIVRVH
CEEEEEECCCCEEEEEEEEEEECCCCCHHHHHHHHHCCCCCCCCCCCEECCCCCEEEEEE
AFNMDGTYTIKAKYTQEGEGFEKESNNDIKTANVIEPNKSIIGSIHSYNDVDYYKFTLNE
EECCCCEEEEEEEECCCCCCCCCCCCCCCEEEEEECCCHHHHCCCCCCCCCEEEEEEECC
KGSLKINLKHNQYGRYGFKVSLVDENNKSIAEFISGGEDINSYSNKLRLSKGTYFVRIEC
CCCEEEEEECCCCCCEEEEEEEEECCCCHHHHHHCCCCHHHHHHCEEEEECCEEEEEEEE
EKWNDEPLQYELNLVYDIEGENYESEPNDYIQDANYIKCDKEYIGNIQSISDRDYYKINL
ECCCCCCEEEEEEEEEEECCCCCCCCCCHHHCCCCEEEECHHHCCCCCCCCCCCEEEEEE
NSDSKITINFKHDEGYGKWTIYLCDKDNKPIKRFKSYGYEISKDFDPVELEAGEYYVSVE
CCCCEEEEEEEECCCCCEEEEEEECCCCCHHHHHHHCCCEECCCCCCEEEECCCEEEEEE
GIDSIDYTINVKREAPDKSNNENKKVKRR
CCCCEEEEEEEEECCCCCCCCCCCCCCCC
>Mature Secondary Structure
MVKSKEKNKIFFTLLAITLIFIVNSNKVKANDEINFRRLDGKERYETSASICSGGWDTSE
CCCCCCCCEEEHHHHHHHHEEEECCCEEECCCCEEEEECCCHHHHHCCHHHHCCCCCCCC
YAVLASGEGFADALSAAPLAKKYDAPIILTGKNKLNDNAKDQLKKLDTKEVIIVGGPGSI
EEEEECCCCHHHHHHCCCCHHHCCCCEEEECCCCCCCCHHHHHHHCCCCCEEEECCCCCC
SEDIVTELKDLGIKVNRIYGEDRYKTSLKIAKEIGVKNGIVVTNGLGFADALGMAPIAAS
HHHHHHHHHHCCEEEEEEECCCHHHHHHHHHHHCCCCCCEEEECCCCHHHHHCCCCCCCC
KQMPILLTPSDKLTSDTMEFLKKSSYNKSYVLGGTATVSDYIKNSLKNPTRLSGADRYKT
CCCCEEECCCCCCCHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHCCCCCCCCCCCHHEE
NIAILNHFKGDLNLDEVYIASGDGYADALSGSVLASKNKSPIILINDNLNKSTKDFVSTN
EEEEEEECCCCCCCCEEEEECCCCCHHHCCCCEEECCCCCCEEEECCCCCCCCHHHHCCC
KYNFKNVTIFGGEAVVKEPTISSLFGAFRSGETRSDTKEVVAEKWDRSYLKDYHIDLPEG
CCCCEEEEEECCCEEEECCCHHHHHHHHHCCCCCCHHHHHHHHHHCHHHHHHEEEECCCC
GKLDIEYDINNFTRFDLIVLDIKNNEIIKKSYNYLKNNKSIHDNYNDIRLPKGKYIVRVH
CEEEEEECCCCEEEEEEEEEEECCCCCHHHHHHHHHCCCCCCCCCCCEECCCCCEEEEEE
AFNMDGTYTIKAKYTQEGEGFEKESNNDIKTANVIEPNKSIIGSIHSYNDVDYYKFTLNE
EECCCCEEEEEEEECCCCCCCCCCCCCCCEEEEEECCCHHHHCCCCCCCCCEEEEEEECC
KGSLKINLKHNQYGRYGFKVSLVDENNKSIAEFISGGEDINSYSNKLRLSKGTYFVRIEC
CCCEEEEEECCCCCCEEEEEEEEECCCCHHHHHHCCCCHHHHHHCEEEEECCEEEEEEEE
EKWNDEPLQYELNLVYDIEGENYESEPNDYIQDANYIKCDKEYIGNIQSISDRDYYKINL
ECCCCCCEEEEEEEEEEECCCCCCCCCCHHHCCCCEEEECHHHCCCCCCCCCCCEEEEEE
NSDSKITINFKHDEGYGKWTIYLCDKDNKPIKRFKSYGYEISKDFDPVELEAGEYYVSVE
CCCCEEEEEEEECCCCCEEEEEEECCCCCHHHHHHHCCCEECCCCCCEEEECCCEEEEEE
GIDSIDYTINVKREAPDKSNNENKKVKRR
CCCCEEEEEEEEECCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1357079; 1682302; 9384377 [H]