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The map label for this gene is baiCD [H]

Identifier: 170756116

GI number: 170756116

Start: 290307

End: 290990

Strand: Direct

Name: baiCD [H]

Synonym: CLD_0533

Alternate gene names: 170756116

Gene position: 290307-290990 (Clockwise)

Preceding gene: 170757272

Following gene: 170756008

Centisome position: 7.33

GC content: 29.24

Gene sequence:

>684_bases
ATGAAGTTATTAAGAGATATAGTAAGAAAATTTGGAGATGCAGCTTTGAGAGCAAAAAAAGCTGGATTTGATGCCGTACA
AATTCATGCAGCTCATGGTTATCTATTAAGCCAATTTTTAACACCTTATTATAATAGAAGAAATGATGAATATGGAGGAG
ATATACACAATAGAGCAAAAATAATTTATGAAACAATAGAAGAAATAAGAAAAAGAGTGGGTAATGATTATCCAATTATG
ATAAAAATTAATTATGATGACCTTATGGAGAAAAATCCTGGTTTGACTACGGAAGAATCTATAGAGGTTTTTAAGAAAAT
GGATGAATTGGGTATAGATATAATTGAACCTAGTGCAGCTAACTTATCTTCAGGCGAAGCTAACTATCCATTTAGAACAG
GAATTAATTCTCTAGAAAAGCAATCATATTTTAAAGAAGACGTAATGAAAATTGCAAGTGAAGTAAAGGCAAAAGTAATT
TTGATGGGAGGAAATAGAAATATTAATTTAATGAATGAAATATTAAATACTACAGAAATTGAATATCTCTCATTATCTAG
ACCTTTACTTGCTGAACCAGATTTAATCAATAAGTGGATGGATAATAAAGATTATAAGCAAAAATGTGTTTCTTGTAATA
GATGTTGGGACGGTTTATCAAACTGCTGCATTTTTAGTAGATAG

Upstream 100 bases:

>100_bases
TTATTTGAAAAAACAAATATTAAAAATTTAGAGATAAAAAATAGATTTATTAGATCAGCAACTTGGGATCGTATGTCAGA
AGATGATGGTCATTTAAATA

Downstream 100 bases:

>100_bases
AATATTAAAAGATGGAATATTAAATGTCATTTTATATTAAATTTAATGATGGCAAATGATTTTTTTCAAAAGTAATTTCA
CGCCAGGGATCATCTTCAAC

Product: oxidoreductase, FAD/FMN-binding

Products: trans-transtetradehydroacyl-CoA; NADPH [C]

Alternate protein names: Bile acid-inducible operon protein C; Bile acid-inducible operon protein D [H]

Number of amino acids: Translated: 227; Mature: 227

Protein sequence:

>227_residues
MKLLRDIVRKFGDAALRAKKAGFDAVQIHAAHGYLLSQFLTPYYNRRNDEYGGDIHNRAKIIYETIEEIRKRVGNDYPIM
IKINYDDLMEKNPGLTTEESIEVFKKMDELGIDIIEPSAANLSSGEANYPFRTGINSLEKQSYFKEDVMKIASEVKAKVI
LMGGNRNINLMNEILNTTEIEYLSLSRPLLAEPDLINKWMDNKDYKQKCVSCNRCWDGLSNCCIFSR

Sequences:

>Translated_227_residues
MKLLRDIVRKFGDAALRAKKAGFDAVQIHAAHGYLLSQFLTPYYNRRNDEYGGDIHNRAKIIYETIEEIRKRVGNDYPIM
IKINYDDLMEKNPGLTTEESIEVFKKMDELGIDIIEPSAANLSSGEANYPFRTGINSLEKQSYFKEDVMKIASEVKAKVI
LMGGNRNINLMNEILNTTEIEYLSLSRPLLAEPDLINKWMDNKDYKQKCVSCNRCWDGLSNCCIFSR
>Mature_227_residues
MKLLRDIVRKFGDAALRAKKAGFDAVQIHAAHGYLLSQFLTPYYNRRNDEYGGDIHNRAKIIYETIEEIRKRVGNDYPIM
IKINYDDLMEKNPGLTTEESIEVFKKMDELGIDIIEPSAANLSSGEANYPFRTGINSLEKQSYFKEDVMKIASEVKAKVI
LMGGNRNINLMNEILNTTEIEYLSLSRPLLAEPDLINKWMDNKDYKQKCVSCNRCWDGLSNCCIFSR

Specific function: Catalyzes The NADP-Dependent Reduction Of 2,4-Dienoyl- CoA To Yield Trans-2- Enoyl-CoA. [C]

COG id: COG1902

COG function: function code C; NADH:flavin oxidoreductases, Old Yellow Enzyme family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family [H]

Homologues:

Organism=Escherichia coli, GI1789463, Length=213, Percent_Identity=28.6384976525822, Blast_Score=103, Evalue=8e-24,
Organism=Escherichia coli, GI1787939, Length=197, Percent_Identity=27.9187817258883, Blast_Score=79, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17565138, Length=198, Percent_Identity=32.8282828282828, Blast_Score=118, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI17540738, Length=199, Percent_Identity=34.1708542713568, Blast_Score=108, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI17559802, Length=196, Percent_Identity=32.6530612244898, Blast_Score=107, Evalue=4e-24,
Organism=Caenorhabditis elegans, GI72001454, Length=198, Percent_Identity=31.8181818181818, Blast_Score=107, Evalue=7e-24,
Organism=Caenorhabditis elegans, GI17564188, Length=199, Percent_Identity=31.1557788944724, Blast_Score=106, Evalue=8e-24,
Organism=Caenorhabditis elegans, GI17559804, Length=199, Percent_Identity=30.1507537688442, Blast_Score=105, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI17566914, Length=200, Percent_Identity=29, Blast_Score=91, Evalue=5e-19,
Organism=Saccharomyces cerevisiae, GI6321973, Length=71, Percent_Identity=43.6619718309859, Blast_Score=69, Evalue=5e-13,
Organism=Saccharomyces cerevisiae, GI6325086, Length=71, Percent_Identity=42.2535211267606, Blast_Score=68, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR013027
- InterPro:   IPR016040
- InterPro:   IPR001155
- InterPro:   IPR001327 [H]

Pfam domain/function: PF00724 Oxidored_FMN; PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: 1.3.1.34 [C]

Molecular weight: Translated: 26077; Mature: 26077

Theoretical pI: Translated: 6.76; Mature: 6.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLLRDIVRKFGDAALRAKKAGFDAVQIHAAHGYLLSQFLTPYYNRRNDEYGGDIHNRAK
CHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHH
IIYETIEEIRKRVGNDYPIMIKINYDDLMEKNPGLTTEESIEVFKKMDELGIDIIEPSAA
HHHHHHHHHHHHCCCCCEEEEEECHHHHHHCCCCCCHHHHHHHHHHHHHHCCEEECCCCC
NLSSGEANYPFRTGINSLEKQSYFKEDVMKIASEVKAKVILMGGNRNINLMNEILNTTEI
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCHHHHHHHHHHHHH
EYLSLSRPLLAEPDLINKWMDNKDYKQKCVSCNRCWDGLSNCCIFSR
HHHCCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHCCEECCC
>Mature Secondary Structure
MKLLRDIVRKFGDAALRAKKAGFDAVQIHAAHGYLLSQFLTPYYNRRNDEYGGDIHNRAK
CHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHH
IIYETIEEIRKRVGNDYPIMIKINYDDLMEKNPGLTTEESIEVFKKMDELGIDIIEPSAA
HHHHHHHHHHHHCCCCCEEEEEECHHHHHHCCCCCCHHHHHHHHHHHHHHCCEEECCCCC
NLSSGEANYPFRTGINSLEKQSYFKEDVMKIASEVKAKVILMGGNRNINLMNEILNTTEI
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCHHHHHHHHHHHHH
EYLSLSRPLLAEPDLINKWMDNKDYKQKCVSCNRCWDGLSNCCIFSR
HHHCCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: FAD. [C]

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: transDidehydroacyl-CoA; NADP+ [C]

Specific reaction: transDidehydroacyl-CoA + NADP+ =trans-transtetradehydroacyl-CoA + NADPH [C]

General reaction: Redox reaction [C]

Inhibitor: Iodoacetic acid; N-Ethyl maleimide [C]

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2254270 [H]