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The map label for this gene is ddc [H]

Identifier: 170756008

GI number: 170756008

Start: 291175

End: 292599

Strand: Direct

Name: ddc [H]

Synonym: CLD_0532

Alternate gene names: 170756008

Gene position: 291175-292599 (Clockwise)

Preceding gene: 170756116

Following gene: 170754353

Centisome position: 7.36

GC content: 33.26

Gene sequence:

>1425_bases
ATGGATATAAATTTAAAGAATGATTTAGAGAATATGGATATTTTATTAGAAAAAATAACAATTAACGCCTTTGATTTTTT
AAAAGATATTAATGAAATAGCGACTTCCCCAAAAAGTACAAATGCTTATACACTTTCTCAATTAAACAAAGATGGGTTAG
GTGGAGAAAAAACATTAGAAGAGTTTATGCAAAGATTTTATAATGGAATAGTTTCATGTGCAGGATCAAAGTATTTTGGT
CTTGTAACTGGAGGTACAACTCCAGCAGCTTTGATGGGCGATTGGTTAGTAAGTACATTTGATCAAAATGCCACAGGCAG
AGATAATTCCAGTGCAGCAAAGCTTGAGGAAGAAACCATAAATTTATTAAAGCAGCTTTTGGGGTTGCCGGAAACATATT
CGGGAACATTTGTAACGGGAGCTACTATGGCTAACTTTGTTGGGCTAGCAATTGGAAGGCAGTGGCTAGCTAATGAATTA
GGTGTTAATATAGCTATAGATGGTCTGTATTCCATTCCACCAATAAAGATTGTAAGTTCTACTCCTCATTCAAGCATTTT
AAAAGCTATGTCTATGCTAGGCATGGGAAGAAAAAATATGCATTATATTCCTACGATTGATGGGAGAGAGGCTGTAGATG
TTGAAGCATTAGAAAGTTATTTAAAAAAGTTGAATGGAGAACCATGTATTGTTGTAGCAAATGCAGGAACAGTAAATACT
GTTGATTTTGATGATTTAAAAGAAATTGGAGAATTGAAGAAAAAATATAATTTTTTTCTCCATGTAGATGGAGCTTTTGG
AGGTTTTGCTTCTTGTTCAATAAAATACAAAAAACTTGTAGAAGGAATTGAAGCGGCAGATTCTATTACTATAGATGCAC
ATAAGTGGTTGAATGTTCCTTATGATAGCGCAATGCAGTTCACTAAACATCCTAAACTTCAACTTCAGGTTTTTCAAAAC
AACGCATTATATCTAGGAGAGCTTTCAGATAAACCTGATTTTGTTCATCTGACTCCAGAAAATTCAAGAAGGTTAAGAGC
TCTTCCTGCATGGTTTACCCTAAAGGCATATGGACAAAATGGATATCAGGAGATAATTGAGAGAAACTGTGATCTAGCAC
AATTGCTAAGTAAAAAAATTCATGAATCTAAAAATTTTAGATTGCTGTCAACTACTAAATTAAATGTAGTTTGCTTCACC
ATTAATCTTGAAAATGGTAATGTTAAATTAGAGCAAATACAGCAATTTTTAAATTTAGTTAATAAGGATGGCAGAGCATT
CTTTACTCAAACAGTATATAAAGGAATAGCAGGAATAAGGGCAGCTATAAGCAATTGGAGGACAGAGGAAAAAGATATTG
AAATCGCATGGGAAGTACTAAATAAGGCATATGAGTCCTATTATGAAACAATAACAGCAGATTGA

Upstream 100 bases:

>100_bases
AGGGATCATCTTCAACTATTAAGATTGATTATATATAATATGATACATATACTATATCACAATATTAAGTTACAAAGAAA
ACCATGAAAGGAGTATATCT

Downstream 100 bases:

>100_bases
TTTAGAAAAGTATTTTACAAGCTTTCAAACAGATAAGAATTTAGAGAAACTTAAGATTTTTCTAGTGTTAAGCACTATTT
TTAGATTCTTATATGTATTA

Product: putative amino acid decarboxylase

Products: NA

Alternate protein names: DABA decarboxylase; DABA-DC [H]

Number of amino acids: Translated: 474; Mature: 474

Protein sequence:

>474_residues
MDINLKNDLENMDILLEKITINAFDFLKDINEIATSPKSTNAYTLSQLNKDGLGGEKTLEEFMQRFYNGIVSCAGSKYFG
LVTGGTTPAALMGDWLVSTFDQNATGRDNSSAAKLEEETINLLKQLLGLPETYSGTFVTGATMANFVGLAIGRQWLANEL
GVNIAIDGLYSIPPIKIVSSTPHSSILKAMSMLGMGRKNMHYIPTIDGREAVDVEALESYLKKLNGEPCIVVANAGTVNT
VDFDDLKEIGELKKKYNFFLHVDGAFGGFASCSIKYKKLVEGIEAADSITIDAHKWLNVPYDSAMQFTKHPKLQLQVFQN
NALYLGELSDKPDFVHLTPENSRRLRALPAWFTLKAYGQNGYQEIIERNCDLAQLLSKKIHESKNFRLLSTTKLNVVCFT
INLENGNVKLEQIQQFLNLVNKDGRAFFTQTVYKGIAGIRAAISNWRTEEKDIEIAWEVLNKAYESYYETITAD

Sequences:

>Translated_474_residues
MDINLKNDLENMDILLEKITINAFDFLKDINEIATSPKSTNAYTLSQLNKDGLGGEKTLEEFMQRFYNGIVSCAGSKYFG
LVTGGTTPAALMGDWLVSTFDQNATGRDNSSAAKLEEETINLLKQLLGLPETYSGTFVTGATMANFVGLAIGRQWLANEL
GVNIAIDGLYSIPPIKIVSSTPHSSILKAMSMLGMGRKNMHYIPTIDGREAVDVEALESYLKKLNGEPCIVVANAGTVNT
VDFDDLKEIGELKKKYNFFLHVDGAFGGFASCSIKYKKLVEGIEAADSITIDAHKWLNVPYDSAMQFTKHPKLQLQVFQN
NALYLGELSDKPDFVHLTPENSRRLRALPAWFTLKAYGQNGYQEIIERNCDLAQLLSKKIHESKNFRLLSTTKLNVVCFT
INLENGNVKLEQIQQFLNLVNKDGRAFFTQTVYKGIAGIRAAISNWRTEEKDIEIAWEVLNKAYESYYETITAD
>Mature_474_residues
MDINLKNDLENMDILLEKITINAFDFLKDINEIATSPKSTNAYTLSQLNKDGLGGEKTLEEFMQRFYNGIVSCAGSKYFG
LVTGGTTPAALMGDWLVSTFDQNATGRDNSSAAKLEEETINLLKQLLGLPETYSGTFVTGATMANFVGLAIGRQWLANEL
GVNIAIDGLYSIPPIKIVSSTPHSSILKAMSMLGMGRKNMHYIPTIDGREAVDVEALESYLKKLNGEPCIVVANAGTVNT
VDFDDLKEIGELKKKYNFFLHVDGAFGGFASCSIKYKKLVEGIEAADSITIDAHKWLNVPYDSAMQFTKHPKLQLQVFQN
NALYLGELSDKPDFVHLTPENSRRLRALPAWFTLKAYGQNGYQEIIERNCDLAQLLSKKIHESKNFRLLSTTKLNVVCFT
INLENGNVKLEQIQQFLNLVNKDGRAFFTQTVYKGIAGIRAAISNWRTEEKDIEIAWEVLNKAYESYYETITAD

Specific function: Unknown

COG id: COG0076

COG function: function code E; Glutamate decarboxylase and related PLP-dependent proteins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the group II decarboxylase family [H]

Homologues:

Organism=Homo sapiens, GI92110055, Length=462, Percent_Identity=23.5930735930736, Blast_Score=116, Evalue=5e-26,
Organism=Homo sapiens, GI4503281, Length=413, Percent_Identity=24.6973365617433, Blast_Score=115, Evalue=6e-26,
Organism=Homo sapiens, GI132814448, Length=413, Percent_Identity=24.6973365617433, Blast_Score=115, Evalue=6e-26,
Organism=Homo sapiens, GI197383062, Length=400, Percent_Identity=26, Blast_Score=112, Evalue=6e-25,
Organism=Homo sapiens, GI197276620, Length=409, Percent_Identity=24.4498777506112, Blast_Score=105, Evalue=8e-23,
Organism=Homo sapiens, GI4503875, Length=409, Percent_Identity=24.4498777506112, Blast_Score=105, Evalue=8e-23,
Organism=Homo sapiens, GI58331246, Length=340, Percent_Identity=26.7647058823529, Blast_Score=102, Evalue=1e-21,
Organism=Homo sapiens, GI194294551, Length=334, Percent_Identity=26.3473053892216, Blast_Score=101, Evalue=2e-21,
Organism=Homo sapiens, GI190341074, Length=250, Percent_Identity=27.6, Blast_Score=75, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17534819, Length=464, Percent_Identity=24.1379310344828, Blast_Score=124, Evalue=7e-29,
Organism=Caenorhabditis elegans, GI17534817, Length=462, Percent_Identity=24.2424242424242, Blast_Score=124, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI17555682, Length=341, Percent_Identity=25.2199413489736, Blast_Score=103, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI71993062, Length=324, Percent_Identity=25.6172839506173, Blast_Score=103, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI71993058, Length=324, Percent_Identity=25.6172839506173, Blast_Score=103, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI71981217, Length=300, Percent_Identity=25.6666666666667, Blast_Score=98, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI71981211, Length=300, Percent_Identity=25.6666666666667, Blast_Score=98, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17551992, Length=284, Percent_Identity=25, Blast_Score=92, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI133931025, Length=238, Percent_Identity=24.7899159663866, Blast_Score=83, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17543922, Length=297, Percent_Identity=23.5690235690236, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24585139, Length=238, Percent_Identity=31.0924369747899, Blast_Score=134, Evalue=2e-31,
Organism=Drosophila melanogaster, GI221476190, Length=238, Percent_Identity=31.0924369747899, Blast_Score=134, Evalue=2e-31,
Organism=Drosophila melanogaster, GI24585143, Length=238, Percent_Identity=31.0924369747899, Blast_Score=134, Evalue=2e-31,
Organism=Drosophila melanogaster, GI24652373, Length=477, Percent_Identity=26.4150943396226, Blast_Score=132, Evalue=5e-31,
Organism=Drosophila melanogaster, GI17136594, Length=387, Percent_Identity=27.6485788113695, Blast_Score=132, Evalue=7e-31,
Organism=Drosophila melanogaster, GI28573972, Length=418, Percent_Identity=27.511961722488, Blast_Score=127, Evalue=1e-29,
Organism=Drosophila melanogaster, GI24586044, Length=456, Percent_Identity=23.6842105263158, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI21356415, Length=352, Percent_Identity=26.1363636363636, Blast_Score=109, Evalue=4e-24,
Organism=Drosophila melanogaster, GI17136190, Length=235, Percent_Identity=25.531914893617, Blast_Score=103, Evalue=4e-22,
Organism=Drosophila melanogaster, GI24585135, Length=235, Percent_Identity=25.531914893617, Blast_Score=102, Evalue=6e-22,
Organism=Drosophila melanogaster, GI24657193, Length=334, Percent_Identity=24.251497005988, Blast_Score=82, Evalue=9e-16,
Organism=Drosophila melanogaster, GI24657185, Length=334, Percent_Identity=24.251497005988, Blast_Score=82, Evalue=9e-16,
Organism=Drosophila melanogaster, GI24657188, Length=334, Percent_Identity=24.251497005988, Blast_Score=82, Evalue=9e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002129
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422
- InterPro:   IPR021115 [H]

Pfam domain/function: PF00282 Pyridoxal_deC [H]

EC number: =4.1.1.86 [H]

Molecular weight: Translated: 52819; Mature: 52819

Theoretical pI: Translated: 5.37; Mature: 5.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDINLKNDLENMDILLEKITINAFDFLKDINEIATSPKSTNAYTLSQLNKDGLGGEKTLE
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEHHHCCCCCCCCHHHHH
EFMQRFYNGIVSCAGSKYFGLVTGGTTPAALMGDWLVSTFDQNATGRDNSSAAKLEEETI
HHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHH
NLLKQLLGLPETYSGTFVTGATMANFVGLAIGRQWLANELGVNIAIDGLYSIPPIKIVSS
HHHHHHHCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHCCCEEEECCEECCCCEEEECC
TPHSSILKAMSMLGMGRKNMHYIPTIDGREAVDVEALESYLKKLNGEPCIVVANAGTVNT
CCHHHHHHHHHHHCCCCCCCEECCCCCCCCCCCHHHHHHHHHHCCCCCEEEEECCCCEEC
VDFDDLKEIGELKKKYNFFLHVDGAFGGFASCSIKYKKLVEGIEAADSITIDAHKWLNVP
CCHHHHHHHHHHHHHCEEEEEECCCCCCCHHCCCHHHHHHHHHHHCCCEEEEHHHHCCCC
YDSAMQFTKHPKLQLQVFQNNALYLGELSDKPDFVHLTPENSRRLRALPAWFTLKAYGQN
HHHHHHHHCCCCEEEEEEECCCEEEEECCCCCCEEEECCCCCCCEEECCCEEEEEECCCC
GYQEIIERNCDLAQLLSKKIHESKNFRLLSTTKLNVVCFTINLENGNVKLEQIQQFLNLV
HHHHHHHCCCCHHHHHHHHHHCCCCEEEEEEEEEEEEEEEEEECCCCEEHHHHHHHHHHH
NKDGRAFFTQTVYKGIAGIRAAISNWRTEEKDIEIAWEVLNKAYESYYETITAD
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDINLKNDLENMDILLEKITINAFDFLKDINEIATSPKSTNAYTLSQLNKDGLGGEKTLE
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEHHHCCCCCCCCHHHHH
EFMQRFYNGIVSCAGSKYFGLVTGGTTPAALMGDWLVSTFDQNATGRDNSSAAKLEEETI
HHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHH
NLLKQLLGLPETYSGTFVTGATMANFVGLAIGRQWLANELGVNIAIDGLYSIPPIKIVSS
HHHHHHHCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHCCCEEEECCEECCCCEEEECC
TPHSSILKAMSMLGMGRKNMHYIPTIDGREAVDVEALESYLKKLNGEPCIVVANAGTVNT
CCHHHHHHHHHHHCCCCCCCEECCCCCCCCCCCHHHHHHHHHHCCCCCEEEEECCCCEEC
VDFDDLKEIGELKKKYNFFLHVDGAFGGFASCSIKYKKLVEGIEAADSITIDAHKWLNVP
CCHHHHHHHHHHHHHCEEEEEECCCCCCCHHCCCHHHHHHHHHHHCCCEEEEHHHHCCCC
YDSAMQFTKHPKLQLQVFQNNALYLGELSDKPDFVHLTPENSRRLRALPAWFTLKAYGQN
HHHHHHHHCCCCEEEEEEECCCEEEEECCCCCCEEEECCCCCCCEEECCCEEEEEECCCC
GYQEIIERNCDLAQLLSKKIHESKNFRLLSTTKLNVVCFTINLENGNVKLEQIQQFLNLV
HHHHHHHCCCCHHHHHHHHHHCCCCEEEEEEEEEEEEEEEEEECCCCEEHHHHHHHHHHH
NKDGRAFFTQTVYKGIAGIRAAISNWRTEEKDIEIAWEVLNKAYESYYETITAD
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800; 9514614 [H]