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The map label for this gene is bcd [H]

Identifier: 170755992

GI number: 170755992

Start: 2382579

End: 2383712

Strand: Reverse

Name: bcd [H]

Synonym: CLD_2384

Alternate gene names: 170755992

Gene position: 2383712-2382579 (Counterclockwise)

Preceding gene: 170754756

Following gene: 170756792

Centisome position: 60.22

GC content: 34.57

Gene sequence:

>1134_bases
ATGTTATTTAAAAAAGAGCATGAACTTTTAAGAAAGTCCGTAAGGGATTTTGTAGATAGGGAATTAAAAGATATTCCAGA
AGAAGTTGATACTGAGGGGAAATTACCTAAAGAGTTATTACAAAAACTTGCAAAATATAAATTCATAAGTCCTGTAATAC
CTAAGGAATATGGTGGAGCTGGAGCAGATTATGTATCATACTGCATAATAATGGAAGAAATCAGTAAAAGATGCGCATCT
ACTGGAACTTTTATAACAGCAGGAGCATCATTGGTAGCATTACCTTTACTTAATTTTGGAACAGATGAGCAAAAAGAAAA
ATATTTAAAGCCTCTTGCTAAAGGAGAATATATTGGATCTTTTGGGCTTACAGAGCCAGGAGCAGGATCTGATGCTGGTG
CGGGACAAACTACAGCAGTTTTAGAGGGAGATTATTATATTCTAAATGGAAGAAAAACATTTATTACAAATGCACCTATT
TGTGACTTTGCTATAGTAACAGCAATGACAGAAAAGGGTAAAGGATCAAGGGGGATTTCAGCCTTTATAGTTGAAAGTAA
ATGGGATGGATTTTCAACAGGAGCTCATGAAAATAAAATGGGCATTAGAGGAACTGAGACAGCGGATTTAATATTTGAAA
ATGTAAAAGTTCCTAAAGAAAACCTTATTGGAAAAGAAGGCAAAGGATTTAAAATAGCTCTAAATACTCTTGATGTTGGT
AGAATCGGGGTAGCAGCTCAAGCTCTTGGAATAGCTCAAGGTGCTTTAGATGAAGCTATAAAATATGTTAAGGAAAGAGT
TCAATTTGGTAGACCTTTAGCAAAATTCCAAAATACTCAATTTACAATTGCAGATATGGAAACAAAGGTTCAAGCTGCAA
GATGGCTTGTATATGATGCAGCAGAGAAAAAAGACAATGGTATAAATCCAGGGGTTGAATCTGCAATGGCTAAATACTAC
GCAGCAGAAATTGCAAATGAAGTAGCATATAAAGCATTACAATTACATGGTGGATATGGATTTATGAAGGATTATCCAAT
AGAAAGAATGTATAGAGATGCTAGAATTACATCCATATATGAAGGTACATCTCAAGTTCAGCAAATGGTTATTGCTGCGA
AAGCTCTTAAATAG

Upstream 100 bases:

>100_bases
ATGAAACTAAAAAAAGTATAGGGATTTATAAATACTTTAAAAAATTAAAATGAAAAATCACTACATTTTATTAAAGGTTT
AAATTTAAAAGGAGGAAAGT

Downstream 100 bases:

>100_bases
ATATATATGAGAAATAAACAAAATTGGAGGTTAAGAATTTGAGGATAGTAGTATGCGTTAAGCAAGTTCCAGATACAACA
GAAGTAAAGATAGATCCTAA

Product: acyl-CoA dehydrogenase family protein

Products: NA

Alternate protein names: Butyryl-CoA dehydrogenase; SCAD [H]

Number of amino acids: Translated: 377; Mature: 377

Protein sequence:

>377_residues
MLFKKEHELLRKSVRDFVDRELKDIPEEVDTEGKLPKELLQKLAKYKFISPVIPKEYGGAGADYVSYCIIMEEISKRCAS
TGTFITAGASLVALPLLNFGTDEQKEKYLKPLAKGEYIGSFGLTEPGAGSDAGAGQTTAVLEGDYYILNGRKTFITNAPI
CDFAIVTAMTEKGKGSRGISAFIVESKWDGFSTGAHENKMGIRGTETADLIFENVKVPKENLIGKEGKGFKIALNTLDVG
RIGVAAQALGIAQGALDEAIKYVKERVQFGRPLAKFQNTQFTIADMETKVQAARWLVYDAAEKKDNGINPGVESAMAKYY
AAEIANEVAYKALQLHGGYGFMKDYPIERMYRDARITSIYEGTSQVQQMVIAAKALK

Sequences:

>Translated_377_residues
MLFKKEHELLRKSVRDFVDRELKDIPEEVDTEGKLPKELLQKLAKYKFISPVIPKEYGGAGADYVSYCIIMEEISKRCAS
TGTFITAGASLVALPLLNFGTDEQKEKYLKPLAKGEYIGSFGLTEPGAGSDAGAGQTTAVLEGDYYILNGRKTFITNAPI
CDFAIVTAMTEKGKGSRGISAFIVESKWDGFSTGAHENKMGIRGTETADLIFENVKVPKENLIGKEGKGFKIALNTLDVG
RIGVAAQALGIAQGALDEAIKYVKERVQFGRPLAKFQNTQFTIADMETKVQAARWLVYDAAEKKDNGINPGVESAMAKYY
AAEIANEVAYKALQLHGGYGFMKDYPIERMYRDARITSIYEGTSQVQQMVIAAKALK
>Mature_377_residues
MLFKKEHELLRKSVRDFVDRELKDIPEEVDTEGKLPKELLQKLAKYKFISPVIPKEYGGAGADYVSYCIIMEEISKRCAS
TGTFITAGASLVALPLLNFGTDEQKEKYLKPLAKGEYIGSFGLTEPGAGSDAGAGQTTAVLEGDYYILNGRKTFITNAPI
CDFAIVTAMTEKGKGSRGISAFIVESKWDGFSTGAHENKMGIRGTETADLIFENVKVPKENLIGKEGKGFKIALNTLDVG
RIGVAAQALGIAQGALDEAIKYVKERVQFGRPLAKFQNTQFTIADMETKVQAARWLVYDAAEKKDNGINPGVESAMAKYY
AAEIANEVAYKALQLHGGYGFMKDYPIERMYRDARITSIYEGTSQVQQMVIAAKALK

Specific function: Unknown

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557233, Length=375, Percent_Identity=47.4666666666667, Blast_Score=363, Evalue=1e-100,
Organism=Homo sapiens, GI4501859, Length=370, Percent_Identity=41.3513513513514, Blast_Score=293, Evalue=2e-79,
Organism=Homo sapiens, GI226958412, Length=373, Percent_Identity=38.3378016085791, Blast_Score=262, Evalue=5e-70,
Organism=Homo sapiens, GI4557231, Length=373, Percent_Identity=37.8016085790885, Blast_Score=253, Evalue=2e-67,
Organism=Homo sapiens, GI187960098, Length=373, Percent_Identity=37.8016085790885, Blast_Score=253, Evalue=2e-67,
Organism=Homo sapiens, GI226958414, Length=370, Percent_Identity=38.1081081081081, Blast_Score=251, Evalue=5e-67,
Organism=Homo sapiens, GI7656849, Length=382, Percent_Identity=37.17277486911, Blast_Score=246, Evalue=3e-65,
Organism=Homo sapiens, GI4501857, Length=374, Percent_Identity=35.5614973262032, Blast_Score=243, Evalue=2e-64,
Organism=Homo sapiens, GI21361497, Length=358, Percent_Identity=38.268156424581, Blast_Score=230, Evalue=2e-60,
Organism=Homo sapiens, GI4557235, Length=328, Percent_Identity=36.5853658536585, Blast_Score=206, Evalue=3e-53,
Organism=Homo sapiens, GI76496475, Length=328, Percent_Identity=36.5853658536585, Blast_Score=206, Evalue=4e-53,
Organism=Homo sapiens, GI4503943, Length=366, Percent_Identity=30.0546448087432, Blast_Score=166, Evalue=2e-41,
Organism=Homo sapiens, GI7669494, Length=356, Percent_Identity=30.3370786516854, Blast_Score=159, Evalue=4e-39,
Organism=Homo sapiens, GI48976061, Length=293, Percent_Identity=31.0580204778157, Blast_Score=128, Evalue=9e-30,
Organism=Homo sapiens, GI211971008, Length=293, Percent_Identity=31.0580204778157, Blast_Score=128, Evalue=1e-29,
Organism=Homo sapiens, GI38505218, Length=401, Percent_Identity=27.930174563591, Blast_Score=125, Evalue=7e-29,
Organism=Homo sapiens, GI218563752, Length=202, Percent_Identity=31.6831683168317, Blast_Score=85, Evalue=1e-16,
Organism=Escherichia coli, GI87081958, Length=381, Percent_Identity=30.7086614173228, Blast_Score=173, Evalue=1e-44,
Organism=Escherichia coli, GI1786223, Length=381, Percent_Identity=29.6587926509186, Blast_Score=171, Evalue=1e-43,
Organism=Escherichia coli, GI87081702, Length=356, Percent_Identity=27.8089887640449, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI87082384, Length=308, Percent_Identity=23.7012987012987, Blast_Score=76, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17508101, Length=370, Percent_Identity=39.4594594594595, Blast_Score=284, Evalue=5e-77,
Organism=Caenorhabditis elegans, GI17534899, Length=345, Percent_Identity=42.0289855072464, Blast_Score=266, Evalue=2e-71,
Organism=Caenorhabditis elegans, GI17506239, Length=368, Percent_Identity=38.3152173913043, Blast_Score=263, Evalue=9e-71,
Organism=Caenorhabditis elegans, GI17570075, Length=370, Percent_Identity=38.3783783783784, Blast_Score=254, Evalue=5e-68,
Organism=Caenorhabditis elegans, GI17569725, Length=369, Percent_Identity=38.2113821138211, Blast_Score=254, Evalue=6e-68,
Organism=Caenorhabditis elegans, GI17533517, Length=377, Percent_Identity=37.6657824933687, Blast_Score=249, Evalue=1e-66,
Organism=Caenorhabditis elegans, GI17538396, Length=364, Percent_Identity=34.8901098901099, Blast_Score=239, Evalue=1e-63,
Organism=Caenorhabditis elegans, GI71990804, Length=270, Percent_Identity=43.7037037037037, Blast_Score=228, Evalue=5e-60,
Organism=Caenorhabditis elegans, GI71985184, Length=359, Percent_Identity=36.7688022284123, Blast_Score=225, Evalue=2e-59,
Organism=Caenorhabditis elegans, GI71982178, Length=275, Percent_Identity=38.5454545454545, Blast_Score=192, Evalue=2e-49,
Organism=Caenorhabditis elegans, GI71985192, Length=294, Percent_Identity=35.7142857142857, Blast_Score=180, Evalue=1e-45,
Organism=Caenorhabditis elegans, GI17534353, Length=366, Percent_Identity=32.5136612021858, Blast_Score=178, Evalue=4e-45,
Organism=Caenorhabditis elegans, GI17551932, Length=374, Percent_Identity=29.9465240641711, Blast_Score=176, Evalue=1e-44,
Organism=Caenorhabditis elegans, GI32563615, Length=225, Percent_Identity=38.6666666666667, Blast_Score=174, Evalue=9e-44,
Organism=Caenorhabditis elegans, GI17505929, Length=374, Percent_Identity=29.144385026738, Blast_Score=172, Evalue=3e-43,
Organism=Caenorhabditis elegans, GI17531909, Length=237, Percent_Identity=37.1308016877637, Blast_Score=158, Evalue=5e-39,
Organism=Caenorhabditis elegans, GI17562446, Length=342, Percent_Identity=32.7485380116959, Blast_Score=138, Evalue=4e-33,
Organism=Caenorhabditis elegans, GI17531913, Length=176, Percent_Identity=34.0909090909091, Blast_Score=106, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI86563381, Length=266, Percent_Identity=30.0751879699248, Blast_Score=96, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI86563383, Length=269, Percent_Identity=29.7397769516729, Blast_Score=96, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17540912, Length=378, Percent_Identity=24.0740740740741, Blast_Score=75, Evalue=7e-14,
Organism=Drosophila melanogaster, GI21356377, Length=375, Percent_Identity=48.2666666666667, Blast_Score=357, Evalue=9e-99,
Organism=Drosophila melanogaster, GI24646207, Length=375, Percent_Identity=42.1333333333333, Blast_Score=308, Evalue=4e-84,
Organism=Drosophila melanogaster, GI24666513, Length=367, Percent_Identity=38.6920980926431, Blast_Score=277, Evalue=8e-75,
Organism=Drosophila melanogaster, GI24660351, Length=366, Percent_Identity=38.2513661202186, Blast_Score=251, Evalue=4e-67,
Organism=Drosophila melanogaster, GI21355753, Length=374, Percent_Identity=36.3636363636364, Blast_Score=244, Evalue=6e-65,
Organism=Drosophila melanogaster, GI281363737, Length=386, Percent_Identity=34.1968911917098, Blast_Score=214, Evalue=6e-56,
Organism=Drosophila melanogaster, GI19920834, Length=373, Percent_Identity=28.9544235924933, Blast_Score=160, Evalue=1e-39,
Organism=Drosophila melanogaster, GI24652780, Length=264, Percent_Identity=26.1363636363636, Blast_Score=73, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: =1.3.99.2 [H]

Molecular weight: Translated: 41327; Mature: 41327

Theoretical pI: Translated: 7.99; Mature: 7.99

Prosite motif: PS00072 ACYL_COA_DH_1 ; PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLFKKEHELLRKSVRDFVDRELKDIPEEVDTEGKLPKELLQKLAKYKFISPVIPKEYGGA
CCCCHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCHHHHHHHHHHHHHCCCCCCHHCCCC
GADYVSYCIIMEEISKRCASTGTFITAGASLVALPLLNFGTDEQKEKYLKPLAKGEYIGS
CHHHHHHHHHHHHHHHHHHCCCCEEECCHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCC
FGLTEPGAGSDAGAGQTTAVLEGDYYILNGRKTFITNAPICDFAIVTAMTEKGKGSRGIS
CCCCCCCCCCCCCCCCEEEEEECCEEEECCCEEEEECCCHHHHHHHHHHHHCCCCCCCCE
AFIVESKWDGFSTGAHENKMGIRGTETADLIFENVKVPKENLIGKEGKGFKIALNTLDVG
EEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCHHHCCCCCCCCEEEEEEEECCC
RIGVAAQALGIAQGALDEAIKYVKERVQFGRPLAKFQNTQFTIADMETKVQAARWLVYDA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCEEEEEHHHHHHHHHHHHHEEC
AEKKDNGINPGVESAMAKYYAAEIANEVAYKALQLHGGYGFMKDYPIERMYRDARITSIY
HHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHH
EGTSQVQQMVIAAKALK
HHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLFKKEHELLRKSVRDFVDRELKDIPEEVDTEGKLPKELLQKLAKYKFISPVIPKEYGGA
CCCCHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCHHHHHHHHHHHHHCCCCCCHHCCCC
GADYVSYCIIMEEISKRCASTGTFITAGASLVALPLLNFGTDEQKEKYLKPLAKGEYIGS
CHHHHHHHHHHHHHHHHHHCCCCEEECCHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCC
FGLTEPGAGSDAGAGQTTAVLEGDYYILNGRKTFITNAPICDFAIVTAMTEKGKGSRGIS
CCCCCCCCCCCCCCCCEEEEEECCEEEECCCEEEEECCCHHHHHHHHHHHHCCCCCCCCE
AFIVESKWDGFSTGAHENKMGIRGTETADLIFENVKVPKENLIGKEGKGFKIALNTLDVG
EEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCHHHCCCCCCCCEEEEEEEECCC
RIGVAAQALGIAQGALDEAIKYVKERVQFGRPLAKFQNTQFTIADMETKVQAARWLVYDA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCEEEEEHHHHHHHHHHHHHEEC
AEKKDNGINPGVESAMAKYYAAEIANEVAYKALQLHGGYGFMKDYPIERMYRDARITSIY
HHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHH
EGTSQVQQMVIAAKALK
HHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8655474; 11466286 [H]