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The map label for this gene is dinB

Identifier: 170755759

GI number: 170755759

Start: 3004949

End: 3005998

Strand: Reverse

Name: dinB

Synonym: CLD_1757

Alternate gene names: 170755759

Gene position: 3005998-3004949 (Counterclockwise)

Preceding gene: 170754614

Following gene: 170754701

Centisome position: 75.94

GC content: 28.86

Gene sequence:

>1050_bases
ATGGATAGAGTTATTATACACGTTGATATGGATGCATTTTTTGCTTCTGTAGAACAAATGGATAATAAAAAACTTAGGGG
TAAACCTGTAATAGTAGGTGGAATAGGAGAAAGAGGAGTAGTTTCTACTGCATCTTATGAGGCAAGAAAATATGGGGTAC
ATTCAGCTATGCCTGTTTTTATAGCTAAAAAGAGATGCCCTTTTGGCATATATGTACCTGGAAGGCATGAGAGATATAAG
GAAGTTTCAAACAATATATTTAAAATATTATATAAGGTTACTCCTATTATTGAGCCTGTATCCATAGATGAAGCATATTT
AGACATCACCAATATTAAAGAAGAACCTATTAAAGTGGCAGAACATATAAAAAAGAAAGTTAAAAATGAAATGGGATTAA
CCTTATCTGTAGGAATTTCATATAATAAATTTCTAGCAAAGCTTGCTTCTGATTGGAATAAACCAGATGGTATAAAAATA
ATAAGGCAAGATATGATTCCAAGCATACTTATGCCACTTCCTATAAACAAGATTCATGGAATAGGTAAAAAGTCAGTGGA
AAAATTAAATAACATAGGTATTTATACTGTGGAAGATATGCATAAGCTATCTAGGGATTTTTGTATAGAGTATTTTGGAA
AATTCGGAGTAGAAATATACGAGAGAATAAGAGGAATAGATTATAGAGAAGTAAAAGTTAGTAGAGAAAGAAAGTCCATA
GGGAAGGAAATAACCCTTAAAAAGGATATAACAAATAAAGAGGAAATGAAAAAATATCTTTTGGATTTTTCAAATAAAGT
ATCTACTAATTTGTATAAAAGAAATAGTGGAGGAAAAACTGTTACTGTAAAAATAAAAACTTCTAATTTTCAAACTCATA
CAAGGAGTAAGACCGTAAATGATTATATAAGGGATAAAGATGAAATTTATAATATAGCCTGTGATATATTAGAACATATA
AATTTTAAGGAACCTATAAGACTTATAGGGCTTACTGTATCAAATTTAGGAGAAAATAAAATTAAGCAATTGACCTTTAA
TATTTATTAA

Upstream 100 bases:

>100_bases
AATGTTAAAAACATCTGTATTTAACTTTTGAAGATTTTGATATAATTATATGTAAGCTATATTAAAGTGTAAATTATAGT
TCAGAGAGGAATTCATATTT

Downstream 100 bases:

>100_bases
GTTAAATAAATTTCAGTAAATATAACTAAAAATAAATATTAATTTAAAGTTTACACAAAACTGTAATTGATTTATAAATA
ATATAAAATATATTGTAAAA

Product: DNA polymerase IV

Products: NA

Alternate protein names: Pol IV [H]

Number of amino acids: Translated: 349; Mature: 349

Protein sequence:

>349_residues
MDRVIIHVDMDAFFASVEQMDNKKLRGKPVIVGGIGERGVVSTASYEARKYGVHSAMPVFIAKKRCPFGIYVPGRHERYK
EVSNNIFKILYKVTPIIEPVSIDEAYLDITNIKEEPIKVAEHIKKKVKNEMGLTLSVGISYNKFLAKLASDWNKPDGIKI
IRQDMIPSILMPLPINKIHGIGKKSVEKLNNIGIYTVEDMHKLSRDFCIEYFGKFGVEIYERIRGIDYREVKVSRERKSI
GKEITLKKDITNKEEMKKYLLDFSNKVSTNLYKRNSGGKTVTVKIKTSNFQTHTRSKTVNDYIRDKDEIYNIACDILEHI
NFKEPIRLIGLTVSNLGENKIKQLTFNIY

Sequences:

>Translated_349_residues
MDRVIIHVDMDAFFASVEQMDNKKLRGKPVIVGGIGERGVVSTASYEARKYGVHSAMPVFIAKKRCPFGIYVPGRHERYK
EVSNNIFKILYKVTPIIEPVSIDEAYLDITNIKEEPIKVAEHIKKKVKNEMGLTLSVGISYNKFLAKLASDWNKPDGIKI
IRQDMIPSILMPLPINKIHGIGKKSVEKLNNIGIYTVEDMHKLSRDFCIEYFGKFGVEIYERIRGIDYREVKVSRERKSI
GKEITLKKDITNKEEMKKYLLDFSNKVSTNLYKRNSGGKTVTVKIKTSNFQTHTRSKTVNDYIRDKDEIYNIACDILEHI
NFKEPIRLIGLTVSNLGENKIKQLTFNIY
>Mature_349_residues
MDRVIIHVDMDAFFASVEQMDNKKLRGKPVIVGGIGERGVVSTASYEARKYGVHSAMPVFIAKKRCPFGIYVPGRHERYK
EVSNNIFKILYKVTPIIEPVSIDEAYLDITNIKEEPIKVAEHIKKKVKNEMGLTLSVGISYNKFLAKLASDWNKPDGIKI
IRQDMIPSILMPLPINKIHGIGKKSVEKLNNIGIYTVEDMHKLSRDFCIEYFGKFGVEIYERIRGIDYREVKVSRERKSI
GKEITLKKDITNKEEMKKYLLDFSNKVSTNLYKRNSGGKTVTVKIKTSNFQTHTRSKTVNDYIRDKDEIYNIACDILEHI
NFKEPIRLIGLTVSNLGENKIKQLTFNIY

Specific function: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits

COG id: COG0389

COG function: function code L; Nucleotidyltransferase/DNA polymerase involved in DNA repair

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 umuC domain [H]

Homologues:

Organism=Homo sapiens, GI84043967, Length=338, Percent_Identity=29.585798816568, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI7706681, Length=339, Percent_Identity=29.2035398230088, Blast_Score=128, Evalue=7e-30,
Organism=Homo sapiens, GI154350220, Length=329, Percent_Identity=27.6595744680851, Blast_Score=122, Evalue=4e-28,
Organism=Homo sapiens, GI5729982, Length=365, Percent_Identity=27.9452054794521, Blast_Score=119, Evalue=3e-27,
Organism=Homo sapiens, GI7705344, Length=115, Percent_Identity=45.2173913043478, Blast_Score=108, Evalue=5e-24,
Organism=Escherichia coli, GI1786425, Length=352, Percent_Identity=39.7727272727273, Blast_Score=236, Evalue=2e-63,
Organism=Escherichia coli, GI1787432, Length=295, Percent_Identity=26.4406779661017, Blast_Score=102, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI17537959, Length=327, Percent_Identity=26.9113149847095, Blast_Score=102, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI193205700, Length=286, Percent_Identity=32.5174825174825, Blast_Score=95, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI193205702, Length=285, Percent_Identity=31.5789473684211, Blast_Score=95, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI115534089, Length=350, Percent_Identity=26.8571428571429, Blast_Score=87, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6324921, Length=271, Percent_Identity=25.0922509225092, Blast_Score=78, Evalue=2e-15,
Organism=Drosophila melanogaster, GI19923006, Length=339, Percent_Identity=25.0737463126844, Blast_Score=120, Evalue=1e-27,
Organism=Drosophila melanogaster, GI21355641, Length=303, Percent_Identity=28.0528052805281, Blast_Score=116, Evalue=3e-26,
Organism=Drosophila melanogaster, GI24644984, Length=303, Percent_Identity=28.0528052805281, Blast_Score=116, Evalue=3e-26,
Organism=Drosophila melanogaster, GI24668444, Length=256, Percent_Identity=27.734375, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017962
- InterPro:   IPR017961
- InterPro:   IPR001126
- InterPro:   IPR017963
- InterPro:   IPR022880 [H]

Pfam domain/function: PF00817 IMS [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 40115; Mature: 40115

Theoretical pI: Translated: 10.05; Mature: 10.05

Prosite motif: PS50173 UMUC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRVIIHVDMDAFFASVEQMDNKKLRGKPVIVGGIGERGVVSTASYEARKYGVHSAMPVF
CCEEEEEEEHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCEECCCHHHHHHCCCCCCHHE
IAKKRCPFGIYVPGRHERYKEVSNNIFKILYKVTPIIEPVSIDEAYLDITNIKEEPIKVA
EECCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHEEHHCCCCHHHHHH
EHIKKKVKNEMGLTLSVGISYNKFLAKLASDWNKPDGIKIIRQDMIPSILMPLPINKIHG
HHHHHHHHHHCCCEEEECCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCHHHHC
IGKKSVEKLNNIGIYTVEDMHKLSRDFCIEYFGKFGVEIYERIRGIDYREVKVSRERKSI
CCHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHC
GKEITLKKDITNKEEMKKYLLDFSNKVSTNLYKRNSGGKTVTVKIKTSNFQTHTRSKTVN
CCEEEEECCCCCHHHHHHHHHHCCCHHHHHHEEECCCCCEEEEEEEECCCCCHHHHHHHH
DYIRDKDEIYNIACDILEHINFKEPIRLIGLTVSNLGENKIKQLTFNIY
HHHCCHHHHHHHHHHHHHHCCCCCCHHEEEEEHHHCCCHHHHHEEEECC
>Mature Secondary Structure
MDRVIIHVDMDAFFASVEQMDNKKLRGKPVIVGGIGERGVVSTASYEARKYGVHSAMPVF
CCEEEEEEEHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCEECCCHHHHHHCCCCCCHHE
IAKKRCPFGIYVPGRHERYKEVSNNIFKILYKVTPIIEPVSIDEAYLDITNIKEEPIKVA
EECCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHEEHHCCCCHHHHHH
EHIKKKVKNEMGLTLSVGISYNKFLAKLASDWNKPDGIKIIRQDMIPSILMPLPINKIHG
HHHHHHHHHHCCCEEEECCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCHHHHC
IGKKSVEKLNNIGIYTVEDMHKLSRDFCIEYFGKFGVEIYERIRGIDYREVKVSRERKSI
CCHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHC
GKEITLKKDITNKEEMKKYLLDFSNKVSTNLYKRNSGGKTVTVKIKTSNFQTHTRSKTVN
CCEEEEECCCCCHHHHHHHHHHCCCHHHHHHEEECCCCCEEEEEEEECCCCCHHHHHHHH
DYIRDKDEIYNIACDILEHINFKEPIRLIGLTVSNLGENKIKQLTFNIY
HHHCCHHHHHHHHHHHHHHCCCCCCHHEEEEEHHHCCCHHHHHEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11997336 [H]