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The map label for this gene is ykuT [H]

Identifier: 170755204

GI number: 170755204

Start: 3943949

End: 3944818

Strand: Reverse

Name: ykuT [H]

Synonym: CLD_0843

Alternate gene names: 170755204

Gene position: 3944818-3943949 (Counterclockwise)

Preceding gene: 170754554

Following gene: 170756806

Centisome position: 99.66

GC content: 25.06

Gene sequence:

>870_bases
ATGAAATCATCATTTAAATTTGATTTTGATTTATCAAAAGGCGGAATAAAAATAGGAGACTTCCTTATAAGTTCAGATTC
TGTATACCATTTTATATCAGTAGTTATTAATATAGCGATTATATGTGCAATAATGTACTTATCTATAAAAATAGGTAATA
AAATAATAAATAGATTTGTTAAAAAACAAAGCAATTTGAAATTTTCATTAGATGATAAAAAAGCTACAACTGTAGGAACT
ATATTAAATAGTATATTAAGATACACAGTTTATTTTGTAGGTATCTTCGCTATAATAGAAATTTTATTTGGAAGAATAGG
TTCTATATTTGCAGGACTTGGTGGTGCAGCTATAGGATTAGGAGCTAAAGATCTTATAAAGGATGTAATAAGTGGATTTT
TTATATTGTTTGAAGATCAATTTTCAGTAGGGGATTATATAACTGTAGAAGATAAATCTGGAATAGTTGATACCATAGAA
CTTAGAGTAACTAAATTAAAAGATTTTAATGGAGATGTTCATATAATACCTAATGGTTTAATAAATAAAGTAACTAATCA
TGCTAAAAATGATATGAGATTTAAGATAGAAATCAATGTAGCTTACGAAGTAAATATAGAAGAAGCAATAAATAAAATTA
ATAAAGTATGTTTAGAGTATTCAAAAGAAAGAGAAGACATAGTAGTAGAACAACCAGCAGTGTATGGAATAACTTCATTA
GGGTCAAATGGAATAAGCATAGCTGTATATGGAAAAACAACTCCAATGAATCAATGGACTGCAGAAATTGAATTAAGAAA
GAAAATATTAATAGAACTAAAAAATGAAAATATAGAAATACCCTATAATAAATTTCAAATTATAAAATAA

Upstream 100 bases:

>100_bases
TTATGAAGATGTAAAAAAAATAATAGAAAGTAAAGAAATAAATATTAAAAATGTATATTTAAAGGAGGGTAAGGACTATC
AATTAGTCATGTAATGTTTT

Downstream 100 bases:

>100_bases
AAGGAGAGATTAGTTATGACTAAGACTTTTGATTTAGGGGATATAGTGGAAATGAAAAAATCTCATCCTTGTGGTCATAA
TAGGTGGGAAATAATAAGGA

Product: mechanosensitive ion channel family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 289; Mature: 289

Protein sequence:

>289_residues
MKSSFKFDFDLSKGGIKIGDFLISSDSVYHFISVVINIAIICAIMYLSIKIGNKIINRFVKKQSNLKFSLDDKKATTVGT
ILNSILRYTVYFVGIFAIIEILFGRIGSIFAGLGGAAIGLGAKDLIKDVISGFFILFEDQFSVGDYITVEDKSGIVDTIE
LRVTKLKDFNGDVHIIPNGLINKVTNHAKNDMRFKIEINVAYEVNIEEAINKINKVCLEYSKEREDIVVEQPAVYGITSL
GSNGISIAVYGKTTPMNQWTAEIELRKKILIELKNENIEIPYNKFQIIK

Sequences:

>Translated_289_residues
MKSSFKFDFDLSKGGIKIGDFLISSDSVYHFISVVINIAIICAIMYLSIKIGNKIINRFVKKQSNLKFSLDDKKATTVGT
ILNSILRYTVYFVGIFAIIEILFGRIGSIFAGLGGAAIGLGAKDLIKDVISGFFILFEDQFSVGDYITVEDKSGIVDTIE
LRVTKLKDFNGDVHIIPNGLINKVTNHAKNDMRFKIEINVAYEVNIEEAINKINKVCLEYSKEREDIVVEQPAVYGITSL
GSNGISIAVYGKTTPMNQWTAEIELRKKILIELKNENIEIPYNKFQIIK
>Mature_289_residues
MKSSFKFDFDLSKGGIKIGDFLISSDSVYHFISVVINIAIICAIMYLSIKIGNKIINRFVKKQSNLKFSLDDKKATTVGT
ILNSILRYTVYFVGIFAIIEILFGRIGSIFAGLGGAAIGLGAKDLIKDVISGFFILFEDQFSVGDYITVEDKSGIVDTIE
LRVTKLKDFNGDVHIIPNGLINKVTNHAKNDMRFKIEINVAYEVNIEEAINKINKVCLEYSKEREDIVVEQPAVYGITSL
GSNGISIAVYGKTTPMNQWTAEIELRKKILIELKNENIEIPYNKFQIIK

Specific function: May play a role in resistance to osmotic downshock [H]

COG id: COG0668

COG function: function code M; Small-conductance mechanosensitive channel

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mscS (TC 1.A.23) family [H]

Homologues:

Organism=Escherichia coli, GI87081787, Length=179, Percent_Identity=26.2569832402235, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI1786670, Length=215, Percent_Identity=25.5813953488372, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1787591, Length=221, Percent_Identity=25.7918552036199, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI2367355, Length=223, Percent_Identity=25.5605381165919, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1789291, Length=278, Percent_Identity=21.9424460431655, Blast_Score=61, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010920
- InterPro:   IPR011066
- InterPro:   IPR006685
- InterPro:   IPR011014 [H]

Pfam domain/function: PF00924 MS_channel [H]

EC number: NA

Molecular weight: Translated: 32325; Mature: 32325

Theoretical pI: Translated: 8.57; Mature: 8.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSSFKFDFDLSKGGIKIGDFLISSDSVYHFISVVINIAIICAIMYLSIKIGNKIINRFV
CCCCEEEEEECCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KKQSNLKFSLDDKKATTVGTILNSILRYTVYFVGIFAIIEILFGRIGSIFAGLGGAAIGL
HHCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCC
GAKDLIKDVISGFFILFEDQFSVGDYITVEDKSGIVDTIELRVTKLKDFNGDVHIIPNGL
CHHHHHHHHHCCEEEEEECCCCCCCEEEEECCCCCEEEEEEEEEEEECCCCCEEEECCHH
INKVTNHAKNDMRFKIEINVAYEVNIEEAINKINKVCLEYSKEREDIVVEQPAVYGITSL
HHHHHHCCCCCEEEEEEEEEEEEECHHHHHHHHHHHHHHHCCCCCCEEEECCCEEEECCC
GSNGISIAVYGKTTPMNQWTAEIELRKKILIELKNENIEIPYNKFQIIK
CCCCEEEEEEECCCCCCHHHHHHHHHHEEEEEECCCCEECCCHHEEEEC
>Mature Secondary Structure
MKSSFKFDFDLSKGGIKIGDFLISSDSVYHFISVVINIAIICAIMYLSIKIGNKIINRFV
CCCCEEEEEECCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KKQSNLKFSLDDKKATTVGTILNSILRYTVYFVGIFAIIEILFGRIGSIFAGLGGAAIGL
HHCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCC
GAKDLIKDVISGFFILFEDQFSVGDYITVEDKSGIVDTIELRVTKLKDFNGDVHIIPNGL
CHHHHHHHHHCCEEEEEECCCCCCCEEEEECCCCCEEEEEEEEEEEECCCCCEEEECCHH
INKVTNHAKNDMRFKIEINVAYEVNIEEAINKINKVCLEYSKEREDIVVEQPAVYGITSL
HHHHHHCCCCCEEEEEEEEEEEEECHHHHHHHHHHHHHHHCCCCCCEEEECCCEEEECCC
GSNGISIAVYGKTTPMNQWTAEIELRKKILIELKNENIEIPYNKFQIIK
CCCCEEEEEEECCCCCCHHHHHHHHHHEEEEEECCCCEECCCHHEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]