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The map label for this gene is pucD [H]

Identifier: 170755102

GI number: 170755102

Start: 3117450

End: 3120005

Strand: Reverse

Name: pucD [H]

Synonym: CLD_1661

Alternate gene names: 170755102

Gene position: 3120005-3117450 (Counterclockwise)

Preceding gene: 170755370

Following gene: 170757832

Centisome position: 78.82

GC content: 33.8

Gene sequence:

>2556_bases
GTGTATGAATTTATATTAAATGAAAGAAATGTATCTGTTTCAGAGGATATTAATTTACTTAAATATTTGAGGGATAATGA
GGATTTAACTTCAGTAAAAAATGGGTGTGCAGAAGGAGCCTGTGGAGCCTGTATGATACTTGTTAATGGTAAGGCACTTA
GAGCCTGTATATGTACAACTGCAAAGGTGAATGGAAAAGATGTTAAGACTGTAGAGGGGTTAACAGAATTTGAAAAAGAT
GTTTTTACTTGGGCTTTTTCTAAAGCTGGAGCAGTACAGTGTGGATATTGTATTCCAGGGATGATAATAAGTGCAAAGGC
ACTTTTAGATAAAAATCTAAATCCAAATAAGAAAGAAATTAAAACTGCTATTAGAGGAAATGTATGTAGATGTACTGGAT
ATGTGAAAATAATAAAAGCCATTGAAATGGCAGCAGAGGCATTTAGAAATGGTAAACTTCCATTTGCGAAAGAATATAAA
GGAAAAATAGGTGAAAATATTCCAAGAATAGATGCAAAAGATAAAATTTTAGGTATAGGAAAATATGTAGATGACATGAA
GATAGAGGGAATGGTTTATGGTTCTGCTTTAAGATCAAAATATCCTAGAGCTTTAGTAAAAAGCATTGATATAAGTGAAG
CTTTAAAGCATCCAGATGTAGAAACAATTATCACAGCAAAAGATATTCCGGGAAAAAGATATATAGGACATATTATAAAA
GATTGGCCTGCAATGATAGATGTGGGTGAGGAAACAAGATATGTTGGAGATTCAGTAGCCTTAGTAGCTGCAAAAAATAA
GAAAGCTTTAAAAGAAATACTTAGTCTAATAAAAGTAGAATATGAAGAATTAGAACCTATTTCTAATCCTAATATTGCAA
TAGCTGAAGATGCTCCTAAAATTCATCCTAAGGGAAATATTTTAACAGTGGAAAAAGTTAATAGAGGAGATGTAGATGAG
GCAATAGCCAATTCTAAGTATGTGGTTACTAATCATTATTCTACTCCCTTTACTGAACATGCTTTTTTAGAGCCTGAAAG
TGCTTTAGCTATGCCAGATGGGGATGGAGTTATTATTTATACAGGAAGCCAAGGTATATATGATGAGCAGAGAGAGATTT
CTGAGCTTTTAGGGCTTCCTAAAGAAAAAGTAAGGACTATTAGCAAATATGTGGGTGGAGGCTTTGGTGGAAAAGAAGAT
ATGAGTGTACAACATCATGCCGCTCTTCTTGCATGGACTATTAAAAAGCCCATTAAAATAACTTTAAGTCGTAAGGAAAG
TATAAAGATTCATCCTAAAAGACATGCTATGGAAATGACAATTACTACTGCATGTGATGAAAAAGGAAATTTAACTGCTT
TTAAAGCAGATATTATATCAGATACTGGTGCCTATGCATCATTAGGAGGACCTGTACTTCAAAGAGCTTGTACTCATGCA
GCTGGCCCATATAAATGCCCTAATGTGAAAATAAAAGGTACCGCTGTATATACTAACAATCCCCCAGGAGGAGCTTTTAG
GGGATTTGGAGTAACACAATCAGTTTTTGGATCAGAGTGTAACTTAAATCTTTTAGCTGAAAAAGTTGGTATATCTCCTT
GGGAAATAAGGTTTAAAAACGCAGTAGAACCTGGAGATGCACTACCTAATGGACAAATTGCTGATAAAGGAACTGCAATT
AAAGAAACTATATTAGCTGTGAAAGATGTATATAAAAAGAGTAAATGTGCAGGAATAGCCTGTTGTATGAAAAACTCAGG
AGTTGGTGTTGGAATACCGGATATTGGAAGATGTAACTTAATAGTAATAGATGGAAAGGTTCATATAAGAACTAGTGCAG
CTTGCATAGGTCAAGGTCTTGGAACAATTCTTACACAAATAATATGTGAAACAATAGGTTTATTACCAGAACAGATAATT
TTAGATTTACCAGATACAAAATTTGCACCAGATTCAGGGACAACTACAGCATCAAGACAAACAGTATTTACTGGAGAGGC
CACAAGAATGGCATCATTAAAGCTTAAGGAAAAATTATTAACTACATCATTAGAAGAGTGTGAAGGTGAAGAATTTTATG
GAGAATATCAAAGTATTACAGATCCTATTAATTCTGATAAAAAGAATCCAGTAAGTCACGTGGCTTATGGCTATGCAACA
CAAGTTGTTATTCTTGACGATGATGGAAAAGTAGAAAGAGTAGTTGCAGCACATGATGTGGGAAAAGCTATAAATTTAAC
TAATGTAGAAGGACAAATTGAAGGTGGAATAGTTATGGGACTTGGGTATGCATTTACAGAAGATTATCCATTAAATAAAT
CTATCCCAACTGCTAAATTTGGCACATTAGGTTTGTTTAGAGCTACTGATATACCAGAAATTGAAACAACAATAATTGAA
AAGAATACTAATGATTTAGCTTATGGTGCAAAAGGAATAGGAGAAATTACAACTATACCAACAGCCCCAGCAGCTCAAGG
TGCTTACTATAAATTTGATGGAAACTTTAGAAAAAAGCTTCCACTTGAGGATACTGCTTATAGAAGGAAAAAATAA

Upstream 100 bases:

>100_bases
AGTAGTCATCGTATAAAGTTCATTTATAGTTTTATGCATTTAGACATATAAAGAGAAAATAATAGGCTTATTGATACATA
AATATATGGGGGTAATAAAT

Downstream 100 bases:

>100_bases
TTTTTTGCATGAAACTATTCTAAAATAGATTTAATTTTAACCATGCAAATATAAAAAAATATATATAAACTGCTTATTTT
TGAAACATTTAAACTTTTTA

Product: xanthine dehydrogenase family protein, molybdopterin-binding subunit

Products: NA

Alternate protein names: XDHase subunit D [H]

Number of amino acids: Translated: 851; Mature: 851

Protein sequence:

>851_residues
MYEFILNERNVSVSEDINLLKYLRDNEDLTSVKNGCAEGACGACMILVNGKALRACICTTAKVNGKDVKTVEGLTEFEKD
VFTWAFSKAGAVQCGYCIPGMIISAKALLDKNLNPNKKEIKTAIRGNVCRCTGYVKIIKAIEMAAEAFRNGKLPFAKEYK
GKIGENIPRIDAKDKILGIGKYVDDMKIEGMVYGSALRSKYPRALVKSIDISEALKHPDVETIITAKDIPGKRYIGHIIK
DWPAMIDVGEETRYVGDSVALVAAKNKKALKEILSLIKVEYEELEPISNPNIAIAEDAPKIHPKGNILTVEKVNRGDVDE
AIANSKYVVTNHYSTPFTEHAFLEPESALAMPDGDGVIIYTGSQGIYDEQREISELLGLPKEKVRTISKYVGGGFGGKED
MSVQHHAALLAWTIKKPIKITLSRKESIKIHPKRHAMEMTITTACDEKGNLTAFKADIISDTGAYASLGGPVLQRACTHA
AGPYKCPNVKIKGTAVYTNNPPGGAFRGFGVTQSVFGSECNLNLLAEKVGISPWEIRFKNAVEPGDALPNGQIADKGTAI
KETILAVKDVYKKSKCAGIACCMKNSGVGVGIPDIGRCNLIVIDGKVHIRTSAACIGQGLGTILTQIICETIGLLPEQII
LDLPDTKFAPDSGTTTASRQTVFTGEATRMASLKLKEKLLTTSLEECEGEEFYGEYQSITDPINSDKKNPVSHVAYGYAT
QVVILDDDGKVERVVAAHDVGKAINLTNVEGQIEGGIVMGLGYAFTEDYPLNKSIPTAKFGTLGLFRATDIPEIETTIIE
KNTNDLAYGAKGIGEITTIPTAPAAQGAYYKFDGNFRKKLPLEDTAYRRKK

Sequences:

>Translated_851_residues
MYEFILNERNVSVSEDINLLKYLRDNEDLTSVKNGCAEGACGACMILVNGKALRACICTTAKVNGKDVKTVEGLTEFEKD
VFTWAFSKAGAVQCGYCIPGMIISAKALLDKNLNPNKKEIKTAIRGNVCRCTGYVKIIKAIEMAAEAFRNGKLPFAKEYK
GKIGENIPRIDAKDKILGIGKYVDDMKIEGMVYGSALRSKYPRALVKSIDISEALKHPDVETIITAKDIPGKRYIGHIIK
DWPAMIDVGEETRYVGDSVALVAAKNKKALKEILSLIKVEYEELEPISNPNIAIAEDAPKIHPKGNILTVEKVNRGDVDE
AIANSKYVVTNHYSTPFTEHAFLEPESALAMPDGDGVIIYTGSQGIYDEQREISELLGLPKEKVRTISKYVGGGFGGKED
MSVQHHAALLAWTIKKPIKITLSRKESIKIHPKRHAMEMTITTACDEKGNLTAFKADIISDTGAYASLGGPVLQRACTHA
AGPYKCPNVKIKGTAVYTNNPPGGAFRGFGVTQSVFGSECNLNLLAEKVGISPWEIRFKNAVEPGDALPNGQIADKGTAI
KETILAVKDVYKKSKCAGIACCMKNSGVGVGIPDIGRCNLIVIDGKVHIRTSAACIGQGLGTILTQIICETIGLLPEQII
LDLPDTKFAPDSGTTTASRQTVFTGEATRMASLKLKEKLLTTSLEECEGEEFYGEYQSITDPINSDKKNPVSHVAYGYAT
QVVILDDDGKVERVVAAHDVGKAINLTNVEGQIEGGIVMGLGYAFTEDYPLNKSIPTAKFGTLGLFRATDIPEIETTIIE
KNTNDLAYGAKGIGEITTIPTAPAAQGAYYKFDGNFRKKLPLEDTAYRRKK
>Mature_851_residues
MYEFILNERNVSVSEDINLLKYLRDNEDLTSVKNGCAEGACGACMILVNGKALRACICTTAKVNGKDVKTVEGLTEFEKD
VFTWAFSKAGAVQCGYCIPGMIISAKALLDKNLNPNKKEIKTAIRGNVCRCTGYVKIIKAIEMAAEAFRNGKLPFAKEYK
GKIGENIPRIDAKDKILGIGKYVDDMKIEGMVYGSALRSKYPRALVKSIDISEALKHPDVETIITAKDIPGKRYIGHIIK
DWPAMIDVGEETRYVGDSVALVAAKNKKALKEILSLIKVEYEELEPISNPNIAIAEDAPKIHPKGNILTVEKVNRGDVDE
AIANSKYVVTNHYSTPFTEHAFLEPESALAMPDGDGVIIYTGSQGIYDEQREISELLGLPKEKVRTISKYVGGGFGGKED
MSVQHHAALLAWTIKKPIKITLSRKESIKIHPKRHAMEMTITTACDEKGNLTAFKADIISDTGAYASLGGPVLQRACTHA
AGPYKCPNVKIKGTAVYTNNPPGGAFRGFGVTQSVFGSECNLNLLAEKVGISPWEIRFKNAVEPGDALPNGQIADKGTAI
KETILAVKDVYKKSKCAGIACCMKNSGVGVGIPDIGRCNLIVIDGKVHIRTSAACIGQGLGTILTQIICETIGLLPEQII
LDLPDTKFAPDSGTTTASRQTVFTGEATRMASLKLKEKLLTTSLEECEGEEFYGEYQSITDPINSDKKNPVSHVAYGYAT
QVVILDDDGKVERVVAAHDVGKAINLTNVEGQIEGGIVMGLGYAFTEDYPLNKSIPTAKFGTLGLFRATDIPEIETTIIE
KNTNDLAYGAKGIGEITTIPTAPAAQGAYYKFDGNFRKKLPLEDTAYRRKK

Specific function: Oxidizes hypoxanthine and xanthine to uric acid [H]

COG id: COG1529

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI91823271, Length=711, Percent_Identity=26.5822784810127, Blast_Score=192, Evalue=1e-48,
Organism=Homo sapiens, GI71773480, Length=704, Percent_Identity=25.1420454545455, Blast_Score=149, Evalue=2e-35,
Organism=Escherichia coli, GI1789230, Length=737, Percent_Identity=29.1723202170963, Blast_Score=288, Evalue=8e-79,
Organism=Escherichia coli, GI1789246, Length=948, Percent_Identity=26.1603375527426, Blast_Score=260, Evalue=2e-70,
Organism=Escherichia coli, GI1786478, Length=732, Percent_Identity=23.9071038251366, Blast_Score=116, Evalue=7e-27,
Organism=Escherichia coli, GI1789232, Length=128, Percent_Identity=41.40625, Blast_Score=99, Evalue=8e-22,
Organism=Escherichia coli, GI1786480, Length=152, Percent_Identity=35.5263157894737, Blast_Score=92, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17540638, Length=716, Percent_Identity=25.6983240223464, Blast_Score=173, Evalue=3e-43,
Organism=Caenorhabditis elegans, GI32566215, Length=715, Percent_Identity=23.7762237762238, Blast_Score=125, Evalue=6e-29,
Organism=Caenorhabditis elegans, GI17539860, Length=756, Percent_Identity=23.1481481481481, Blast_Score=114, Evalue=3e-25,
Organism=Drosophila melanogaster, GI17737937, Length=686, Percent_Identity=27.1137026239067, Blast_Score=178, Evalue=2e-44,
Organism=Drosophila melanogaster, GI24647193, Length=691, Percent_Identity=24.0231548480463, Blast_Score=120, Evalue=3e-27,
Organism=Drosophila melanogaster, GI24647199, Length=645, Percent_Identity=22.7906976744186, Blast_Score=105, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24647201, Length=657, Percent_Identity=23.2876712328767, Blast_Score=99, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24647197, Length=148, Percent_Identity=29.0540540540541, Blast_Score=73, Evalue=8e-13,
Organism=Drosophila melanogaster, GI24647195, Length=148, Percent_Identity=29.0540540540541, Blast_Score=73, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000674
- InterPro:   IPR008274
- InterPro:   IPR017609 [H]

Pfam domain/function: PF01315 Ald_Xan_dh_C; PF02738 Ald_Xan_dh_C2 [H]

EC number: =1.17.1.4 [H]

Molecular weight: Translated: 92285; Mature: 92285

Theoretical pI: Translated: 7.67; Mature: 7.67

Prosite motif: PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYEFILNERNVSVSEDINLLKYLRDNEDLTSVKNGCAEGACGACMILVNGKALRACICTT
CCEEEECCCCCCHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCEEEEEECCCEEEEEEEEC
AKVNGKDVKTVEGLTEFEKDVFTWAFSKAGAVQCGYCIPGMIISAKALLDKNLNPNKKEI
CCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCHHHHHHHHHCCCCCCCHHHH
KTAIRGNVCRCTGYVKIIKAIEMAAEAFRNGKLPFAKEYKGKIGENIPRIDAKDKILGIG
HHHHCCCEEEEHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCHHCCCCCCCCCCCCEEECC
KYVDDMKIEGMVYGSALRSKYPRALVKSIDISEALKHPDVETIITAKDIPGKRYIGHIIK
CHHCCEEECEEEEHHHHHHHHHHHHHHHCCHHHHHCCCCCEEEEEECCCCCHHHHHHHHH
DWPAMIDVGEETRYVGDSVALVAAKNKKALKEILSLIKVEYEELEPISNPNIAIAEDAPK
CCHHHEECCCCHHCCCCCEEEEEECCHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCC
IHPKGNILTVEKVNRGDVDEAIANSKYVVTNHYSTPFTEHAFLEPESALAMPDGDGVIIY
CCCCCCEEEEEECCCCCHHHHHCCCCEEEEECCCCCCCCCEEECCCCCEECCCCCEEEEE
TGSQGIYDEQREISELLGLPKEKVRTISKYVGGGFGGKEDMSVQHHAALLAWTIKKPIKI
ECCCCCCHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHEEEEEEECCCEEE
TLSRKESIKIHPKRHAMEMTITTACDEKGNLTAFKADIISDTGAYASLGGPVLQRACTHA
EEECCCCEEECCCCCEEEEEEEEECCCCCCEEEEEEEHHCCCCCCHHCCHHHHHHHHHHC
AGPYKCPNVKIKGTAVYTNNPPGGAFRGFGVTQSVFGSECNLNLLAEKVGISPWEIRFKN
CCCCCCCCEEEEEEEEEECCCCCCCCCCCCCCHHHCCCCCCCEEHHHHHCCCCEEEEECC
AVEPGDALPNGQIADKGTAIKETILAVKDVYKKSKCAGIACCMKNSGVGVGIPDIGRCNL
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCEECCCCCCCEEE
IVIDGKVHIRTSAACIGQGLGTILTQIICETIGLLPEQIILDLPDTKFAPDSGTTTASRQ
EEECCEEEEEEHHHHHHCCHHHHHHHHHHHHHCCCCHHHEEECCCCCCCCCCCCCCCCCC
TVFTGEATRMASLKLKEKLLTTSLEECEGEEFYGEYQSITDPINSDKKNPVSHVAYGYAT
EEEECCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCHHHHEECEEE
QVVILDDDGKVERVVAAHDVGKAINLTNVEGQIEGGIVMGLGYAFTEDYPLNKSIPTAKF
EEEEECCCCCEEEEEEHHHCCCEEEEECCCCEECCCEEEEECEEECCCCCCCCCCCCCCC
GTLGLFRATDIPEIETTIIEKNTNDLAYGAKGIGEITTIPTAPAAQGAYYKFDGNFRKKL
CCEEEEECCCCCCCEEEEEECCCCCHHCCCCCCCCEEECCCCCCCCCCEEEECCCCCCCC
PLEDTAYRRKK
CCCCCHHHCCC
>Mature Secondary Structure
MYEFILNERNVSVSEDINLLKYLRDNEDLTSVKNGCAEGACGACMILVNGKALRACICTT
CCEEEECCCCCCHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCEEEEEECCCEEEEEEEEC
AKVNGKDVKTVEGLTEFEKDVFTWAFSKAGAVQCGYCIPGMIISAKALLDKNLNPNKKEI
CCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCHHHHHHHHHCCCCCCCHHHH
KTAIRGNVCRCTGYVKIIKAIEMAAEAFRNGKLPFAKEYKGKIGENIPRIDAKDKILGIG
HHHHCCCEEEEHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCHHCCCCCCCCCCCCEEECC
KYVDDMKIEGMVYGSALRSKYPRALVKSIDISEALKHPDVETIITAKDIPGKRYIGHIIK
CHHCCEEECEEEEHHHHHHHHHHHHHHHCCHHHHHCCCCCEEEEEECCCCCHHHHHHHHH
DWPAMIDVGEETRYVGDSVALVAAKNKKALKEILSLIKVEYEELEPISNPNIAIAEDAPK
CCHHHEECCCCHHCCCCCEEEEEECCHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCC
IHPKGNILTVEKVNRGDVDEAIANSKYVVTNHYSTPFTEHAFLEPESALAMPDGDGVIIY
CCCCCCEEEEEECCCCCHHHHHCCCCEEEEECCCCCCCCCEEECCCCCEECCCCCEEEEE
TGSQGIYDEQREISELLGLPKEKVRTISKYVGGGFGGKEDMSVQHHAALLAWTIKKPIKI
ECCCCCCHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHEEEEEEECCCEEE
TLSRKESIKIHPKRHAMEMTITTACDEKGNLTAFKADIISDTGAYASLGGPVLQRACTHA
EEECCCCEEECCCCCEEEEEEEEECCCCCCEEEEEEEHHCCCCCCHHCCHHHHHHHHHHC
AGPYKCPNVKIKGTAVYTNNPPGGAFRGFGVTQSVFGSECNLNLLAEKVGISPWEIRFKN
CCCCCCCCEEEEEEEEEECCCCCCCCCCCCCCHHHCCCCCCCEEHHHHHCCCCEEEEECC
AVEPGDALPNGQIADKGTAIKETILAVKDVYKKSKCAGIACCMKNSGVGVGIPDIGRCNL
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCEECCCCCCCEEE
IVIDGKVHIRTSAACIGQGLGTILTQIICETIGLLPEQIILDLPDTKFAPDSGTTTASRQ
EEECCEEEEEEHHHHHHCCHHHHHHHHHHHHHCCCCHHHEEECCCCCCCCCCCCCCCCCC
TVFTGEATRMASLKLKEKLLTTSLEECEGEEFYGEYQSITDPINSDKKNPVSHVAYGYAT
EEEECCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCHHHHEECEEE
QVVILDDDGKVERVVAAHDVGKAINLTNVEGQIEGGIVMGLGYAFTEDYPLNKSIPTAKF
EEEEECCCCCEEEEEEHHHCCCEEEEECCCCEECCCEEEEECEEECCCCCCCCCCCCCCC
GTLGLFRATDIPEIETTIIEKNTNDLAYGAKGIGEITTIPTAPAAQGAYYKFDGNFRKKL
CCEEEEECCCCCCCEEEEEECCCCCHHCCCCCCCCEEECCCCCCCCCCEEEECCCCCCCC
PLEDTAYRRKK
CCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377; 11344136 [H]