Click here to switch to the map view.

The map label for this gene is etfA [H]

Identifier: 170754986

GI number: 170754986

Start: 1119760

End: 1120962

Strand: Direct

Name: etfA [H]

Synonym: CLD_3558

Alternate gene names: 170754986

Gene position: 1119760-1120962 (Clockwise)

Preceding gene: 170757646

Following gene: 170756040

Centisome position: 28.29

GC content: 31.84

Gene sequence:

>1203_bases
ATGGGAAAATTAGTAGTAAATGAAGAAAAATTAACTCCTTCAATTATAGGGGAATTAGTTAAAATATGTCCTTTTGGAGC
ACTAGGAGAAAACAGCGGAAAAATAGAAATTTCAGCAGCCTGTAAAATGTGTAAGCTATGTGTTAAAAAAGGGCCAGCTG
GTGTTATGGAATTTGTAGAAGAAGAAAAATCACATATAGATAAGAGTATTTGGAAAGGCATAGCTGTATATGTAGATCAC
GTAGATGGAGATATTCATCCAGTAACTTACGAGCTTATAGGCAAAGCAAGAGAATTAGCGAATAAAATCAATCATCCAGT
ATATGCAGTATTTATTGGTCATGATATAAAGGAAAAAGCAGAAGAAATACTTCATTATGGAGTAGATGAAGTATTTGTAT
ACGATAATGAAAAATTGAAAGATTTTAGAATAGAACCATACACTAAAGCTATGGAAGATTTCATAAGCAAAGATAAACCA
TCTACATTATTAGTAGGTGCAACAACAATAGGAAGATCTCTTGCACCAAGAGTAGCAGCTAGATTTAGAACAGGACTTAC
AGCAGATTGTACAATATTAGATATAAAGGAAAATACAGATTTAGTACAAATAAGACCAGCCTTTGGTGGAAATATAATGG
CGCAAATAATAAATCCTAATAATAGACCTCAACTTGCAACAGTAAGATATAAGGTTATGGATGCACCAGAGCGAAGTGAA
GAAAAAAGTGGAAAAGTAACTCTTTGTAGCATAGACAAAAGTCAGTTAGATTCACAAATAAAAGTATTAAAGGTAACAAA
GAAACAAGTAGAAGAAAGCATATCAGATGCGGATATAATAATTGCAGTTGGAAGAGGACTTAAAAAAGAAAAAGATTTAG
ATATGATAAATGAACTAGCAGAATTAATAGGTGCTCAAATAGCTACAACAAGACCATTAATAGAAGCGGGATGGACAGAT
GCAAAACGTCAAATAGGTTTGAGTGGAAGAACAGTAAAACCTAAACTTATAATTACTTGTGGTATATCAGGCGCTGTACA
ATTTACAGCAGGAATGAATAATGCAGAGTGTATAGTAGCTATAAATAAAGATCCGAAGGCATCTATATTTAATGTAGCTC
ATTATGGAATAATAGGAGATATTTATGAAGTAATACCAACACTTATAAATAATATAAAAGAAGGTAAAAGATTAACTGTA
TAA

Upstream 100 bases:

>100_bases
TGGACAGGGAGCGGAGAAGAATTAGGAAATAAGTTAACAGCAAAACTTAAAGAATTGAAATTTGTATAAAATAAAGTAAT
ACTAATGGGAGGCTTTTAAT

Downstream 100 bases:

>100_bases
TTGCTAGAGTATTTAAGGACCAATTAACTAACTGATAATTCAATTTTGGAGGTAATTATTATGGAATATAAAAAATTAGA
TGTTAAAGATATAGAGTTTT

Product: electron transfer flavoprotein, alpha subunit/FixB family protein

Products: NA

Alternate protein names: Alpha-ETF; Electron transfer flavoprotein large subunit; ETFLS [H]

Number of amino acids: Translated: 400; Mature: 399

Protein sequence:

>400_residues
MGKLVVNEEKLTPSIIGELVKICPFGALGENSGKIEISAACKMCKLCVKKGPAGVMEFVEEEKSHIDKSIWKGIAVYVDH
VDGDIHPVTYELIGKARELANKINHPVYAVFIGHDIKEKAEEILHYGVDEVFVYDNEKLKDFRIEPYTKAMEDFISKDKP
STLLVGATTIGRSLAPRVAARFRTGLTADCTILDIKENTDLVQIRPAFGGNIMAQIINPNNRPQLATVRYKVMDAPERSE
EKSGKVTLCSIDKSQLDSQIKVLKVTKKQVEESISDADIIIAVGRGLKKEKDLDMINELAELIGAQIATTRPLIEAGWTD
AKRQIGLSGRTVKPKLIITCGISGAVQFTAGMNNAECIVAINKDPKASIFNVAHYGIIGDIYEVIPTLINNIKEGKRLTV

Sequences:

>Translated_400_residues
MGKLVVNEEKLTPSIIGELVKICPFGALGENSGKIEISAACKMCKLCVKKGPAGVMEFVEEEKSHIDKSIWKGIAVYVDH
VDGDIHPVTYELIGKARELANKINHPVYAVFIGHDIKEKAEEILHYGVDEVFVYDNEKLKDFRIEPYTKAMEDFISKDKP
STLLVGATTIGRSLAPRVAARFRTGLTADCTILDIKENTDLVQIRPAFGGNIMAQIINPNNRPQLATVRYKVMDAPERSE
EKSGKVTLCSIDKSQLDSQIKVLKVTKKQVEESISDADIIIAVGRGLKKEKDLDMINELAELIGAQIATTRPLIEAGWTD
AKRQIGLSGRTVKPKLIITCGISGAVQFTAGMNNAECIVAINKDPKASIFNVAHYGIIGDIYEVIPTLINNIKEGKRLTV
>Mature_399_residues
GKLVVNEEKLTPSIIGELVKICPFGALGENSGKIEISAACKMCKLCVKKGPAGVMEFVEEEKSHIDKSIWKGIAVYVDHV
DGDIHPVTYELIGKARELANKINHPVYAVFIGHDIKEKAEEILHYGVDEVFVYDNEKLKDFRIEPYTKAMEDFISKDKPS
TLLVGATTIGRSLAPRVAARFRTGLTADCTILDIKENTDLVQIRPAFGGNIMAQIINPNNRPQLATVRYKVMDAPERSEE
KSGKVTLCSIDKSQLDSQIKVLKVTKKQVEESISDADIIIAVGRGLKKEKDLDMINELAELIGAQIATTRPLIEAGWTDA
KRQIGLSGRTVKPKLIITCGISGAVQFTAGMNNAECIVAINKDPKASIFNVAHYGIIGDIYEVIPTLINNIKEGKRLTV

Specific function: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) [H]

COG id: COG2025

COG function: function code C; Electron transfer flavoprotein, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ETF alpha-subunit/fixB family [H]

Homologues:

Organism=Homo sapiens, GI4503607, Length=330, Percent_Identity=28.4848484848485, Blast_Score=132, Evalue=6e-31,
Organism=Homo sapiens, GI189181759, Length=268, Percent_Identity=30.2238805970149, Blast_Score=125, Evalue=5e-29,
Organism=Escherichia coli, GI1787990, Length=316, Percent_Identity=32.9113924050633, Blast_Score=142, Evalue=3e-35,
Organism=Escherichia coli, GI1786226, Length=308, Percent_Identity=27.5974025974026, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI87082157, Length=266, Percent_Identity=27.4436090225564, Blast_Score=91, Evalue=9e-20,
Organism=Caenorhabditis elegans, GI17506929, Length=318, Percent_Identity=29.2452830188679, Blast_Score=125, Evalue=4e-29,
Organism=Saccharomyces cerevisiae, GI6325261, Length=304, Percent_Identity=30.2631578947368, Blast_Score=126, Evalue=5e-30,
Organism=Drosophila melanogaster, GI17136898, Length=340, Percent_Identity=30, Blast_Score=135, Evalue=6e-32,
Organism=Drosophila melanogaster, GI24652801, Length=340, Percent_Identity=30, Blast_Score=135, Evalue=6e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001308
- InterPro:   IPR014730
- InterPro:   IPR014731
- InterPro:   IPR018206
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01012 ETF; PF00766 ETF_alpha [H]

EC number: NA

Molecular weight: Translated: 43928; Mature: 43796

Theoretical pI: Translated: 7.44; Mature: 7.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKLVVNEEKLTPSIIGELVKICPFGALGENSGKIEISAACKMCKLCVKKGPAGVMEFVE
CCCEEECCCCCCHHHHHHHHHHCCCCCCCCCCCEEEEHHHHHHHHHHHHCCCHHHHHHHH
EEKSHIDKSIWKGIAVYVDHVDGDIHPVTYELIGKARELANKINHPVYAVFIGHDIKEKA
HHHHHHHHHHHCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHH
EEILHYGVDEVFVYDNEKLKDFRIEPYTKAMEDFISKDKPSTLLVGATTIGRSLAPRVAA
HHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHH
RFRTGLTADCTILDIKENTDLVQIRPAFGGNIMAQIINPNNRPQLATVRYKVMDAPERSE
HHHCCCCCCEEEEEECCCCCEEEEECCCCCCEEEEEECCCCCCCEEEEEEEEECCCCCCC
EKSGKVTLCSIDKSQLDSQIKVLKVTKKQVEESISDADIIIAVGRGLKKEKDLDMINELA
CCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHH
ELIGAQIATTRPLIEAGWTDAKRQIGLSGRTVKPKLIITCGISGAVQFTAGMNNAECIVA
HHHCCHHHCCCCHHHCCCCCHHHHCCCCCCEECCEEEEEECCCCEEEEECCCCCCEEEEE
INKDPKASIFNVAHYGIIGDIYEVIPTLINNIKEGKRLTV
ECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
GKLVVNEEKLTPSIIGELVKICPFGALGENSGKIEISAACKMCKLCVKKGPAGVMEFVE
CCEEECCCCCCHHHHHHHHHHCCCCCCCCCCCEEEEHHHHHHHHHHHHCCCHHHHHHHH
EEKSHIDKSIWKGIAVYVDHVDGDIHPVTYELIGKARELANKINHPVYAVFIGHDIKEKA
HHHHHHHHHHHCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHH
EEILHYGVDEVFVYDNEKLKDFRIEPYTKAMEDFISKDKPSTLLVGATTIGRSLAPRVAA
HHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHH
RFRTGLTADCTILDIKENTDLVQIRPAFGGNIMAQIINPNNRPQLATVRYKVMDAPERSE
HHHCCCCCCEEEEEECCCCCEEEEECCCCCCEEEEEECCCCCCCEEEEEEEEECCCCCCC
EKSGKVTLCSIDKSQLDSQIKVLKVTKKQVEESISDADIIIAVGRGLKKEKDLDMINELA
CCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHH
ELIGAQIATTRPLIEAGWTDAKRQIGLSGRTVKPKLIITCGISGAVQFTAGMNNAECIVA
HHHCCHHHCCCCHHHCCCCCHHHHCCCCCCEECCEEEEEECCCCEEEEECCCCCCEEEEE
INKDPKASIFNVAHYGIIGDIYEVIPTLINNIKEGKRLTV
ECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9694853 [H]