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The map label for this gene is ipk

Identifier: 170754962

GI number: 170754962

Start: 158216

End: 159058

Strand: Direct

Name: ipk

Synonym: CLD_0665

Alternate gene names: 170754962

Gene position: 158216-159058 (Clockwise)

Preceding gene: 170755898

Following gene: 170755987

Centisome position: 4.0

GC content: 27.64

Gene sequence:

>843_bases
ATGTTATCAAAAGCTCATGCTAAAATAAATTTATCCTTAGATGTAATAGGAAAAAGAAAAGACGGATATCACCTTTTAAA
GATGTTAATGCAAACCATAGATTTATATGATTTAATAGAAATAAAAAAAATAAAAAAAGATATAATAATAGATTGTGATA
GAGAGTATATACCTAAAGATAGGAGAAATTTGGCATATAAAGCAGCAAGCTTATTTTTAGATAGATACAATATAGATTCT
GGAGTTAGAATAAACATAACTAAAAATATACCAGTAGCAGCAGGATTAGCAGGGGGAAGCACAGATGCGGCTACGGTATT
GAAAATAATGAGAGATATATTTGAGCCAGACATAAGTAATGAAGAATTAAAAGAGATAGCTTTAGATATTGGGGCAGATG
TGCCGTTTTGTATAGAGGGTGGGACAGCTCTTTGTGAAGGTATAGGAGAAAAAATTACTTCCATAAAAAATTTTAAAAAT
CAAATATTAGTATTAGTTAAACCTAATTTTGGGTTATCTACAAAAGATGTATACAATAATTTAAAAGTAGAAAAAATATA
TATTCATCCTAATACAACAAAATTAATACAATCAATAGAAGAAGATAATTTGGAATCTGTAGCTAGAAATATGAGGAATG
TCTTGGAAAACGTTACATTAAGAAAATACAAGACATTAAATTCTATAAAAAGTAATTTTATAGAGTTAGGAGCATTAGGA
AGTATGATGAGTGGTAGCGGACCAAGTGTATTTGGATTATTTGATGACATGCTAAAGGCTCAAATATGTTATGATAATAT
GAAAGAAAAGTATAAAGAAGTATTTATAACAAGAACAATATAA

Upstream 100 bases:

>100_bases
TAGCATAGGATTAAAGCTACAATTTATGAATATCATGATTGTAGCTTTAATTTTTTTGATGTATTATATATTCTATAATA
TATATTTTTGGAGGAATAAA

Downstream 100 bases:

>100_bases
TAGTTAAAAGACCATAGAAATATATTTCAAGAATTATCTATATGGTCTTTTTTTTATTATCTTAATATTTGTATATAAAC
AGAGTTCTTGGTGGCTGTCG

Product: 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase

Products: NA

Alternate protein names: CMK; 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase [H]

Number of amino acids: Translated: 280; Mature: 280

Protein sequence:

>280_residues
MLSKAHAKINLSLDVIGKRKDGYHLLKMLMQTIDLYDLIEIKKIKKDIIIDCDREYIPKDRRNLAYKAASLFLDRYNIDS
GVRINITKNIPVAAGLAGGSTDAATVLKIMRDIFEPDISNEELKEIALDIGADVPFCIEGGTALCEGIGEKITSIKNFKN
QILVLVKPNFGLSTKDVYNNLKVEKIYIHPNTTKLIQSIEEDNLESVARNMRNVLENVTLRKYKTLNSIKSNFIELGALG
SMMSGSGPSVFGLFDDMLKAQICYDNMKEKYKEVFITRTI

Sequences:

>Translated_280_residues
MLSKAHAKINLSLDVIGKRKDGYHLLKMLMQTIDLYDLIEIKKIKKDIIIDCDREYIPKDRRNLAYKAASLFLDRYNIDS
GVRINITKNIPVAAGLAGGSTDAATVLKIMRDIFEPDISNEELKEIALDIGADVPFCIEGGTALCEGIGEKITSIKNFKN
QILVLVKPNFGLSTKDVYNNLKVEKIYIHPNTTKLIQSIEEDNLESVARNMRNVLENVTLRKYKTLNSIKSNFIELGALG
SMMSGSGPSVFGLFDDMLKAQICYDNMKEKYKEVFITRTI
>Mature_280_residues
MLSKAHAKINLSLDVIGKRKDGYHLLKMLMQTIDLYDLIEIKKIKKDIIIDCDREYIPKDRRNLAYKAASLFLDRYNIDS
GVRINITKNIPVAAGLAGGSTDAATVLKIMRDIFEPDISNEELKEIALDIGADVPFCIEGGTALCEGIGEKITSIKNFKN
QILVLVKPNFGLSTKDVYNNLKVEKIYIHPNTTKLIQSIEEDNLESVARNMRNVLENVTLRKYKTLNSIKSNFIELGALG
SMMSGSGPSVFGLFDDMLKAQICYDNMKEKYKEVFITRTI

Specific function: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol [H]

COG id: COG1947

COG function: function code I; 4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GHMP kinase family. IspE subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787459, Length=270, Percent_Identity=30.7407407407407, Blast_Score=103, Evalue=9e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006204
- InterPro:   IPR013750
- InterPro:   IPR004424
- InterPro:   IPR020568
- InterPro:   IPR014721 [H]

Pfam domain/function: PF08544 GHMP_kinases_C; PF00288 GHMP_kinases_N [H]

EC number: =2.7.1.148 [H]

Molecular weight: Translated: 31490; Mature: 31490

Theoretical pI: Translated: 8.55; Mature: 8.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSKAHAKINLSLDVIGKRKDGYHLLKMLMQTIDLYDLIEIKKIKKDIIIDCDREYIPKD
CCCCCCEEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCHHHCCCH
RRNLAYKAASLFLDRYNIDSGVRINITKNIPVAAGLAGGSTDAATVLKIMRDIFEPDISN
HHHHHHHHHHHHHHHCCCCCCEEEEEECCCCEEEECCCCCCHHHHHHHHHHHHHCCCCCH
EELKEIALDIGADVPFCIEGGTALCEGIGEKITSIKNFKNQILVLVKPNFGLSTKDVYNN
HHHHHHHHHHCCCCCEEECCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHCC
LKVEKIYIHPNTTKLIQSIEEDNLESVARNMRNVLENVTLRKYKTLNSIKSNFIELGALG
CEEEEEEECCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SMMSGSGPSVFGLFDDMLKAQICYDNMKEKYKEVFITRTI
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEECC
>Mature Secondary Structure
MLSKAHAKINLSLDVIGKRKDGYHLLKMLMQTIDLYDLIEIKKIKKDIIIDCDREYIPKD
CCCCCCEEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCHHHCCCH
RRNLAYKAASLFLDRYNIDSGVRINITKNIPVAAGLAGGSTDAATVLKIMRDIFEPDISN
HHHHHHHHHHHHHHHCCCCCCEEEEEECCCCEEEECCCCCCHHHHHHHHHHHHHCCCCCH
EELKEIALDIGADVPFCIEGGTALCEGIGEKITSIKNFKNQILVLVKPNFGLSTKDVYNN
HHHHHHHHHHCCCCCEEECCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHCC
LKVEKIYIHPNTTKLIQSIEEDNLESVARNMRNVLENVTLRKYKTLNSIKSNFIELGALG
CEEEEEEECCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SMMSGSGPSVFGLFDDMLKAQICYDNMKEKYKEVFITRTI
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA