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The map label for this gene is hypE

Identifier: 170754871

GI number: 170754871

Start: 1955091

End: 1956095

Strand: Reverse

Name: hypE

Synonym: CLD_2807

Alternate gene names: 170754871

Gene position: 1956095-1955091 (Counterclockwise)

Preceding gene: 170754472

Following gene: 170757268

Centisome position: 49.42

GC content: 28.86

Gene sequence:

>1005_bases
GTGAATGAATTTATTACATTAAGTCATGGGCATGGAGGCAAATATACTCATGATCTTATAGAAAAGCTTATGTATAAATA
TTTTAATAATAAAACTCTCATAGAAGGTATAGATTCTGCAACTTTTAATATAGAAAAAGGAAAGTTAGCCTTTACTACAG
ATTCCTTTGTAGTAAAACCCTTATTTTTCAATGGGGGAGATATAGGAAAGTTGGCTGTATGTGGTACTGTGAATGATTTG
TCTGTATCTGGAGCTAAACCTCTTTATTTAAGCTGTTCCTTTATAATAGAAGAGGGATTTCCTATAGAAAAATTAGAGAT
TATAGTAAAATCTATGACAAACACTGCTAAAGAAGCTAACGTTTTAATAGTAACAGGAGATACTAAGGTGGTAGAAAAAG
GATCTGTAGATCAAATTTTTATAAATACTTCAGGCATAGGAATTATAGAAGAGCAATATTCTATTAAAAATATTGAAGAA
GGTGATAAAGTTATAGTTACAGGAAACGTAGGGGATCATGGAACAGCTATAGCTTTAGATAGGTATAATTTAAACATAAA
AGGAAATTTTAAAAGCGATTGTACACCAGTCAATGCTATAACTAACAAATTAAAAGAATACTATCCTTATATAAAAGTGA
TGAAAGATCCTACTAGGGGAGGAATTGCTACAACTTTAAATGAAATATCATCACTAAGTAAAAATTTAGGCATATGTGTT
TGGGAAGATAAAATACCTATAAAAAATGAAGTTAAAGCAATAAATGAAATGTTAGGTCTAGATCCTTTATACATGGCCTG
TGAAGGAAGAATAGTTATGGTGGTAAAAGATCAATATGCAAAGGATATACTAAAAATCATAAAAGAAATAGATAATTGTA
AAAATGCAGAAATAATAGGTACTTTTGTGAAAAATTCATACAATATAGTATATGTAGAAAATTTTTTAGGTGGCACACGA
ATAATAAATATGTTAGAAGGAGATATGCTTCCAAGAATATGTTAA

Upstream 100 bases:

>100_bases
AAATAACTGACTTTTAAACAGAAAGGTAGAATCGTAAATTGATGATTTAGTTTAAATACTTTCCAAAGAATAATTCTAAG
ATACAAGGAGGAAATATGCA

Downstream 100 bases:

>100_bases
ATACATTCTAGTTAATTAAAAAGTTTATTTTAAGTTATGATGATTAAGTTCCTATAAAGTTAGAAAATATCATAGATGAA
CTTATATCTCTTTATTATAC

Product: hydrogenase expression/formation protein HypE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 334; Mature: 334

Protein sequence:

>334_residues
MNEFITLSHGHGGKYTHDLIEKLMYKYFNNKTLIEGIDSATFNIEKGKLAFTTDSFVVKPLFFNGGDIGKLAVCGTVNDL
SVSGAKPLYLSCSFIIEEGFPIEKLEIIVKSMTNTAKEANVLIVTGDTKVVEKGSVDQIFINTSGIGIIEEQYSIKNIEE
GDKVIVTGNVGDHGTAIALDRYNLNIKGNFKSDCTPVNAITNKLKEYYPYIKVMKDPTRGGIATTLNEISSLSKNLGICV
WEDKIPIKNEVKAINEMLGLDPLYMACEGRIVMVVKDQYAKDILKIIKEIDNCKNAEIIGTFVKNSYNIVYVENFLGGTR
IINMLEGDMLPRIC

Sequences:

>Translated_334_residues
MNEFITLSHGHGGKYTHDLIEKLMYKYFNNKTLIEGIDSATFNIEKGKLAFTTDSFVVKPLFFNGGDIGKLAVCGTVNDL
SVSGAKPLYLSCSFIIEEGFPIEKLEIIVKSMTNTAKEANVLIVTGDTKVVEKGSVDQIFINTSGIGIIEEQYSIKNIEE
GDKVIVTGNVGDHGTAIALDRYNLNIKGNFKSDCTPVNAITNKLKEYYPYIKVMKDPTRGGIATTLNEISSLSKNLGICV
WEDKIPIKNEVKAINEMLGLDPLYMACEGRIVMVVKDQYAKDILKIIKEIDNCKNAEIIGTFVKNSYNIVYVENFLGGTR
IINMLEGDMLPRIC
>Mature_334_residues
MNEFITLSHGHGGKYTHDLIEKLMYKYFNNKTLIEGIDSATFNIEKGKLAFTTDSFVVKPLFFNGGDIGKLAVCGTVNDL
SVSGAKPLYLSCSFIIEEGFPIEKLEIIVKSMTNTAKEANVLIVTGDTKVVEKGSVDQIFINTSGIGIIEEQYSIKNIEE
GDKVIVTGNVGDHGTAIALDRYNLNIKGNFKSDCTPVNAITNKLKEYYPYIKVMKDPTRGGIATTLNEISSLSKNLGICV
WEDKIPIKNEVKAINEMLGLDPLYMACEGRIVMVVKDQYAKDILKIIKEIDNCKNAEIIGTFVKNSYNIVYVENFLGGTR
IINMLEGDMLPRIC

Specific function: Unknown

COG id: COG0309

COG function: function code O; Hydrogenase maturation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypE family [H]

Homologues:

Organism=Escherichia coli, GI226510967, Length=337, Percent_Identity=40.6528189910979, Blast_Score=264, Evalue=5e-72,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR011854
- InterPro:   IPR016188 [H]

Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C [H]

EC number: NA

Molecular weight: Translated: 36982; Mature: 36982

Theoretical pI: Translated: 5.50; Mature: 5.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNEFITLSHGHGGKYTHDLIEKLMYKYFNNKTLIEGIDSATFNIEKGKLAFTTDSFVVKP
CCCEEEEECCCCCCHHHHHHHHHHHHHHCCCEEEECCCCCEEEEECCEEEEEECCEEEEE
LFFNGGDIGKLAVCGTVNDLSVSGAKPLYLSCSFIIEEGFPIEKLEIIVKSMTNTAKEAN
EEECCCCCCEEEEEECCCCCCCCCCCCEEEEEEEEEECCCCHHHHHHHHHHHHCCHHHCE
VLIVTGDTKVVEKGSVDQIFINTSGIGIIEEQYSIKNIEEGDKVIVTGNVGDHGTAIALD
EEEEECCCEEEECCCCCEEEEECCCCEEEECCCCCCCCCCCCEEEEECCCCCCCCEEEEE
RYNLNIKGNFKSDCTPVNAITNKLKEYYPYIKVMKDPTRGGIATTLNEISSLSKNLGICV
EEEEEEECCCCCCCCCHHHHHHHHHHHCCEEEEEECCCCCCHHHHHHHHHHHHHHCCEEE
WEDKIPIKNEVKAINEMLGLDPLYMACEGRIVMVVKDQYAKDILKIIKEIDNCKNAEIIG
EECCCCCHHHHHHHHHHHCCCCEEEECCCEEEEEECCHHHHHHHHHHHHHHCCCCCEEEE
TFVKNSYNIVYVENFLGGTRIINMLEGDMLPRIC
EECCCCEEEEEEECCCCHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MNEFITLSHGHGGKYTHDLIEKLMYKYFNNKTLIEGIDSATFNIEKGKLAFTTDSFVVKP
CCCEEEEECCCCCCHHHHHHHHHHHHHHCCCEEEECCCCCEEEEECCEEEEEECCEEEEE
LFFNGGDIGKLAVCGTVNDLSVSGAKPLYLSCSFIIEEGFPIEKLEIIVKSMTNTAKEAN
EEECCCCCCEEEEEECCCCCCCCCCCCEEEEEEEEEECCCCHHHHHHHHHHHHCCHHHCE
VLIVTGDTKVVEKGSVDQIFINTSGIGIIEEQYSIKNIEEGDKVIVTGNVGDHGTAIALD
EEEEECCCEEEECCCCCEEEEECCCCEEEECCCCCCCCCCCCEEEEECCCCCCCCEEEEE
RYNLNIKGNFKSDCTPVNAITNKLKEYYPYIKVMKDPTRGGIATTLNEISSLSKNLGICV
EEEEEEECCCCCCCCCHHHHHHHHHHHCCEEEEEECCCCCCHHHHHHHHHHHHHHCCEEE
WEDKIPIKNEVKAINEMLGLDPLYMACEGRIVMVVKDQYAKDILKIIKEIDNCKNAEIIG
EECCCCCHHHHHHHHHHHCCCCEEEECCCEEEEEECCHHHHHHHHHHHHHHCCCCCEEEE
TFVKNSYNIVYVENFLGGTRIINMLEGDMLPRIC
EECCCCEEEEEEECCCCHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8510650; 7906310; 12597275 [H]