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The map label for this gene is nrdR

Identifier: 170754467

GI number: 170754467

Start: 2656968

End: 2657423

Strand: Reverse

Name: nrdR

Synonym: CLD_2106

Alternate gene names: 170754467

Gene position: 2657423-2656968 (Counterclockwise)

Preceding gene: 170757352

Following gene: 170755258

Centisome position: 67.14

GC content: 29.39

Gene sequence:

>456_bases
TTGAAGTGTCCCTACTGTGCATATGGAGAAAGCAAAGTGGTAGATTCAAGATCTACAGAGGATGGGAGTTCCATAAGAAG
AAGAAGAGAATGTCTAAAATGTAATAGAAGATATACTACCTATGAAAAAATAGAAACTACACCTATTCTTGTTATAAAAA
AAAATATGAGTAGGGAATATTTTGATAGAAATAAGATAGTAAATGGTCTTATGAAAGCTTGTCAAAAGAGACCAGTGTCA
AGAAAGCAAATTGAACAAATAGCAAATGAAGTGGAAAGGCATATAAGCAATGAAATGCTTACAGAAGTAAATACAGATAA
AATAGGGCAAATAATAATGAAGAATTTAAAAAAGATAGATGAAGTATCTTATGTTAGGTTTGCGTCTGTATATAGACAGT
TTAAAGATATTAATACCTTTATGGAAGAGATTAAAAATCTAATGGATAAGAATTAA

Upstream 100 bases:

>100_bases
ATTGAAAATTTAAGTATATAGTAGAAAAAATGGAGAAAAAGTGTATAATTAATATATATAGCTAAATTTTAGTAATCTAA
AGAAAAGGATGTGGATTAAA

Downstream 100 bases:

>100_bases
GTATAAAGAATTAAAATTAATTTAAGCATGTAAAAACTTAATGCTATTATGGTAATAGTATTGGGTTTTTTATTTTGTAA
TTTTTATCATATGACTACCC

Product: transcriptional regulator NrdR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 151; Mature: 151

Protein sequence:

>151_residues
MKCPYCAYGESKVVDSRSTEDGSSIRRRRECLKCNRRYTTYEKIETTPILVIKKNMSREYFDRNKIVNGLMKACQKRPVS
RKQIEQIANEVERHISNEMLTEVNTDKIGQIIMKNLKKIDEVSYVRFASVYRQFKDINTFMEEIKNLMDKN

Sequences:

>Translated_151_residues
MKCPYCAYGESKVVDSRSTEDGSSIRRRRECLKCNRRYTTYEKIETTPILVIKKNMSREYFDRNKIVNGLMKACQKRPVS
RKQIEQIANEVERHISNEMLTEVNTDKIGQIIMKNLKKIDEVSYVRFASVYRQFKDINTFMEEIKNLMDKN
>Mature_151_residues
MKCPYCAYGESKVVDSRSTEDGSSIRRRRECLKCNRRYTTYEKIETTPILVIKKNMSREYFDRNKIVNGLMKACQKRPVS
RKQIEQIANEVERHISNEMLTEVNTDKIGQIIMKNLKKIDEVSYVRFASVYRQFKDINTFMEEIKNLMDKN

Specific function: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes

COG id: COG1327

COG function: function code K; Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-cone domain

Homologues:

Organism=Escherichia coli, GI1786615, Length=149, Percent_Identity=45.6375838926174, Blast_Score=142, Evalue=1e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NRDR_CLOB1 (A7FW99)

Other databases:

- EMBL:   CP000726
- RefSeq:   YP_001384710.1
- STRING:   A7FW99
- GeneID:   5397760
- GenomeReviews:   CP000726_GR
- KEGG:   cba:CLB_2406
- eggNOG:   COG1327
- HOGENOM:   HBG351755
- OMA:   FASVYRD
- ProtClustDB:   PRK00464
- BioCyc:   CBOT441770:CLB_2406-MONOMER
- GO:   GO:0006350
- HAMAP:   MF_00440
- InterPro:   IPR005144
- InterPro:   IPR003796
- TIGRFAMs:   TIGR00244

Pfam domain/function: PF03477 ATP-cone

EC number: NA

Molecular weight: Translated: 17933; Mature: 17933

Theoretical pI: Translated: 9.85; Mature: 9.85

Prosite motif: PS51161 ATP_CONE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.3 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
7.9 %Cys+Met (Translated Protein)
3.3 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
7.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKCPYCAYGESKVVDSRSTEDGSSIRRRRECLKCNRRYTTYEKIETTPILVIKKNMSREY
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHCCCCEEEEECHHHHHH
FDRNKIVNGLMKACQKRPVSRKQIEQIANEVERHISNEMLTEVNTDKIGQIIMKNLKKID
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
EVSYVRFASVYRQFKDINTFMEEIKNLMDKN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKCPYCAYGESKVVDSRSTEDGSSIRRRRECLKCNRRYTTYEKIETTPILVIKKNMSREY
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHCCCCEEEEECHHHHHH
FDRNKIVNGLMKACQKRPVSRKQIEQIANEVERHISNEMLTEVNTDKIGQIIMKNLKKID
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
EVSYVRFASVYRQFKDINTFMEEIKNLMDKN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA