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The map label for this gene is yafV [C]

Identifier: 170754289

GI number: 170754289

Start: 1943615

End: 1944451

Strand: Reverse

Name: yafV [C]

Synonym: CLD_2819

Alternate gene names: 170754289

Gene position: 1944451-1943615 (Counterclockwise)

Preceding gene: 170757424

Following gene: 170755306

Centisome position: 49.12

GC content: 30.35

Gene sequence:

>837_bases
ATGGATAAGTTAAAAATAGCTTTATGCCAAATGCAAGTTCAAAAGGAAAAGAAAAAAAATATAAAAAAAGCTATAGAAAT
GCTAACAAAAGCTAAAAAAGAAAACTGTAACATAGCAGTTCTACCGGAAATGTTCAATTGCCCCTATGAAAATAAATGTT
TTAAACCTTATGGAGAAATAATAAATGAAGAAAATGGGGGAGAAACTGTAAAAGCTATAAAAAAAGCTGCAAAAGATTTA
GAGCTTTATATTGTAGCAGGTTCTATTCCTGAAATAGAAGGGGATAAAATTTATAATACATCTATGGTATTTGACAATAA
AGGTGTTTTAATAGCTAAGCATAGAAAAGTTCACTTATTTGATATAGATGTAAAAGGGGGAGTGACCTTTAAAGAATCTG
ATACATTGACTGCTGGAAATAAAATAACACTCTTTAACACTCCCTGGGGTAAATTAGGGGTAATGATATGTTACGATATA
AGATTCCCAGAACTTTCAAGAATAATGGCTGTTAAGGGGGCTAAAATTATATTTACTCCAGCAGCTTTTAATATGACTAC
AGGGCCTGCTCATTGGGATACTTTATTTAAAAGTAGGGCATTAGATAATCAAGTCTATATGGTAGGTGTAGCACCTGCTA
GGGATGAAAATAGTAATTATGTATCTTATGGTAATTCATTAATTGCTAGCCCTTGGGGAAATATACTAGCTAAATTAGAT
GCAAAAGAAGATATACTTTTTTCAGAAATAGATTTAGACTATGAAAGTAAAATAAGAGAAGAACTACCTCTATTAAAACA
TATAAGAAAAGACATATATAGTTTAGCAGAAGTTTAA

Upstream 100 bases:

>100_bases
AATTATATTATAATCAAACTAATATTATATCTATATTATACTTTTTAATATTTTCTTAAATTAATAAGCTTGTTATAATA
ATTTAAGCTGGAGGAGTTTT

Downstream 100 bases:

>100_bases
TTTAGCAATCTAAATAATTGTATGTTAAAATTGAAATAGCCTTCAGAGAAGTTATATTCTTTGAAGGTTATTTTGAAATT
TTTACATTATATTATAAAGC

Product: carbon-nitrogen family hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 278; Mature: 278

Protein sequence:

>278_residues
MDKLKIALCQMQVQKEKKKNIKKAIEMLTKAKKENCNIAVLPEMFNCPYENKCFKPYGEIINEENGGETVKAIKKAAKDL
ELYIVAGSIPEIEGDKIYNTSMVFDNKGVLIAKHRKVHLFDIDVKGGVTFKESDTLTAGNKITLFNTPWGKLGVMICYDI
RFPELSRIMAVKGAKIIFTPAAFNMTTGPAHWDTLFKSRALDNQVYMVGVAPARDENSNYVSYGNSLIASPWGNILAKLD
AKEDILFSEIDLDYESKIREELPLLKHIRKDIYSLAEV

Sequences:

>Translated_278_residues
MDKLKIALCQMQVQKEKKKNIKKAIEMLTKAKKENCNIAVLPEMFNCPYENKCFKPYGEIINEENGGETVKAIKKAAKDL
ELYIVAGSIPEIEGDKIYNTSMVFDNKGVLIAKHRKVHLFDIDVKGGVTFKESDTLTAGNKITLFNTPWGKLGVMICYDI
RFPELSRIMAVKGAKIIFTPAAFNMTTGPAHWDTLFKSRALDNQVYMVGVAPARDENSNYVSYGNSLIASPWGNILAKLD
AKEDILFSEIDLDYESKIREELPLLKHIRKDIYSLAEV
>Mature_278_residues
MDKLKIALCQMQVQKEKKKNIKKAIEMLTKAKKENCNIAVLPEMFNCPYENKCFKPYGEIINEENGGETVKAIKKAAKDL
ELYIVAGSIPEIEGDKIYNTSMVFDNKGVLIAKHRKVHLFDIDVKGGVTFKESDTLTAGNKITLFNTPWGKLGVMICYDI
RFPELSRIMAVKGAKIIFTPAAFNMTTGPAHWDTLFKSRALDNQVYMVGVAPARDENSNYVSYGNSLIASPWGNILAKLD
AKEDILFSEIDLDYESKIREELPLLKHIRKDIYSLAEV

Specific function: Unknown

COG id: COG0388

COG function: function code R; Predicted amidohydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 CN hydrolase domain [H]

Homologues:

Organism=Homo sapiens, GI9910460, Length=275, Percent_Identity=43.6363636363636, Blast_Score=275, Evalue=4e-74,
Organism=Homo sapiens, GI5031947, Length=278, Percent_Identity=33.0935251798561, Blast_Score=191, Evalue=8e-49,
Organism=Homo sapiens, GI297632350, Length=274, Percent_Identity=32.8467153284672, Blast_Score=190, Evalue=1e-48,
Organism=Homo sapiens, GI297632348, Length=274, Percent_Identity=32.8467153284672, Blast_Score=190, Evalue=1e-48,
Organism=Homo sapiens, GI297632346, Length=198, Percent_Identity=33.3333333333333, Blast_Score=124, Evalue=1e-28,
Organism=Homo sapiens, GI7706509, Length=260, Percent_Identity=25, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17556280, Length=280, Percent_Identity=35, Blast_Score=189, Evalue=1e-48,
Organism=Caenorhabditis elegans, GI17533173, Length=303, Percent_Identity=24.4224422442244, Blast_Score=83, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6323383, Length=277, Percent_Identity=43.6823104693141, Blast_Score=251, Evalue=8e-68,
Organism=Saccharomyces cerevisiae, GI6322335, Length=301, Percent_Identity=28.9036544850498, Blast_Score=144, Evalue=2e-35,
Organism=Drosophila melanogaster, GI21355835, Length=273, Percent_Identity=43.956043956044, Blast_Score=254, Evalue=6e-68,
Organism=Drosophila melanogaster, GI17933642, Length=272, Percent_Identity=35.2941176470588, Blast_Score=176, Evalue=2e-44,
Organism=Drosophila melanogaster, GI21358471, Length=271, Percent_Identity=27.3062730627306, Blast_Score=89, Evalue=4e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003010
- InterPro:   IPR001110 [H]

Pfam domain/function: PF00795 CN_hydrolase [H]

EC number: 3.5.-.- [C]

Molecular weight: Translated: 31335; Mature: 31335

Theoretical pI: Translated: 8.43; Mature: 8.43

Prosite motif: PS50263 CN_HYDROLASE ; PS01227 UPF0012

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKLKIALCQMQVQKEKKKNIKKAIEMLTKAKKENCNIAVLPEMFNCPYENKCFKPYGEI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECHHHHCCCCCCCCCCHHHHH
INEENGGETVKAIKKAAKDLELYIVAGSIPEIEGDKIYNTSMVFDNKGVLIAKHRKVHLF
HCCCCCCHHHHHHHHHHCCEEEEEEECCCCCCCCCEEEEEEEEECCCCEEEEECCEEEEE
DIDVKGGVTFKESDTLTAGNKITLFNTPWGKLGVMICYDIRFPELSRIMAVKGAKIIFTP
EEEECCCEEECCCCCEECCCEEEEEECCCCCEEEEEEEECCCCHHHHHHHCCCCEEEEEC
AAFNMTTGPAHWDTLFKSRALDNQVYMVGVAPARDENSNYVSYGNSLIASPWGNILAKLD
CCCCCCCCCHHHHHHHHHHCCCCEEEEEEECCCCCCCCCEEECCCEEEECCHHHHHEECC
AKEDILFSEIDLDYESKIREELPLLKHIRKDIYSLAEV
CCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDKLKIALCQMQVQKEKKKNIKKAIEMLTKAKKENCNIAVLPEMFNCPYENKCFKPYGEI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECHHHHCCCCCCCCCCHHHHH
INEENGGETVKAIKKAAKDLELYIVAGSIPEIEGDKIYNTSMVFDNKGVLIAKHRKVHLF
HCCCCCCHHHHHHHHHHCCEEEEEEECCCCCCCCCEEEEEEEEECCCCEEEEECCEEEEE
DIDVKGGVTFKESDTLTAGNKITLFNTPWGKLGVMICYDIRFPELSRIMAVKGAKIIFTP
EEEECCCEEECCCCCEECCCEEEEEECCCCCEEEEEEEECCCCHHHHHHHCCCCEEEEEC
AAFNMTTGPAHWDTLFKSRALDNQVYMVGVAPARDENSNYVSYGNSLIASPWGNILAKLD
CCCCCCCCCHHHHHHHHHHCCCCEEEEEEECCCCCCCCCEEECCCEEEECCHHHHHEECC
AKEDILFSEIDLDYESKIREELPLLKHIRKDIYSLAEV
CCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]