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The map label for this gene is cycW [H]

Identifier: 170752136

GI number: 170752136

Start: 6076868

End: 6077536

Strand: Direct

Name: cycW [H]

Synonym: Mrad2831_5769

Alternate gene names: 170752136

Gene position: 6076868-6077536 (Clockwise)

Preceding gene: 170752135

Following gene: NA

Centisome position: 99.98

GC content: 74.14

Gene sequence:

>669_bases
GTGATTCGCGCGGTCCTCGCCCTCATCGCCCGCGACCTGCGCCTCGCCGGCCGGGTCGGCGGGTCCGGCGCCCTGTCGCT
GGTCTTCTTCCTGATGATCGTCGCGCTGGTGCCCTTCGCCCTCGGGCCCGATCTCAACCTGCTGTCGCGGATCGGCCCGG
CGATCCTGTGGCTCGCCGCCGTGCTGGCGACGCTGATCGGCCTCGACCGCCTGTTCCAGGCCGACGAGGAGGACGGCTCC
CTCGACCTGATGACCGCGGCACCGGTGCCCCTCGAACTGGTGGTGCTCGGCAAGGTCGCGGCGCACTGGCTGACAACCGG
ACTGCCGCTGGCGCTGGCCGCGCCGCTCTTCGGCCTGCTGGTGGCCCTCGACGGCACCGCCATGGGCGCGACGTCCCTGA
CGCTTCTGGCCGGCACGCCGGCCCTGAGCTTCATCGGCGCGGTGGGCGCGGCGCTCACCGCCTCGATTCGCCGGGGCGGC
CTGATCCTCGCCGTGCTGGTCCTGCCGCTGATGATCCCGACGCTGATCTTCGGCGTCTCGGCCGCGCAGGCGGCGAGCGG
CGGGACGGTGCCGTTCCTCGTGCCGCTGGCGGTGCTGGCGGCGCTGACGCTGATCGCCGCCGTGGTCGGGACGCTGGCGG
CGGCGGCGGCTCTGCGCTGGCCGGAATAG

Upstream 100 bases:

>100_bases
TCGCCGCCACCCACCAGTCCCTCGGCCTCGCCGGCGCTGCGGAACTGCGCATCGAGACCGCCGCCGCGGCACCGGTCGCG
GACCTTCTGGAGGAGTGGGC

Downstream 100 bases:

>100_bases
CCGACGCTCTCTTGCATGAAGCGGCCAGCGCTCGTCATCGTCCCGGCGATGCTGCCTCGCGCGGCCGGACGTCTTCGCTG
AAGCCTGCCGAATGCTTCCC

Product: heme exporter protein CcmB

Products: NA

Alternate protein names: Cytochrome c-type biogenesis protein CycW [H]

Number of amino acids: Translated: 222; Mature: 222

Protein sequence:

>222_residues
MIRAVLALIARDLRLAGRVGGSGALSLVFFLMIVALVPFALGPDLNLLSRIGPAILWLAAVLATLIGLDRLFQADEEDGS
LDLMTAAPVPLELVVLGKVAAHWLTTGLPLALAAPLFGLLVALDGTAMGATSLTLLAGTPALSFIGAVGAALTASIRRGG
LILAVLVLPLMIPTLIFGVSAAQAASGGTVPFLVPLAVLAALTLIAAVVGTLAAAAALRWPE

Sequences:

>Translated_222_residues
MIRAVLALIARDLRLAGRVGGSGALSLVFFLMIVALVPFALGPDLNLLSRIGPAILWLAAVLATLIGLDRLFQADEEDGS
LDLMTAAPVPLELVVLGKVAAHWLTTGLPLALAAPLFGLLVALDGTAMGATSLTLLAGTPALSFIGAVGAALTASIRRGG
LILAVLVLPLMIPTLIFGVSAAQAASGGTVPFLVPLAVLAALTLIAAVVGTLAAAAALRWPE
>Mature_222_residues
MIRAVLALIARDLRLAGRVGGSGALSLVFFLMIVALVPFALGPDLNLLSRIGPAILWLAAVLATLIGLDRLFQADEEDGS
LDLMTAAPVPLELVVLGKVAAHWLTTGLPLALAAPLFGLLVALDGTAMGATSLTLLAGTPALSFIGAVGAALTASIRRGG
LILAVLVLPLMIPTLIFGVSAAQAASGGTVPFLVPLAVLAALTLIAAVVGTLAAAAALRWPE

Specific function: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes [H]

COG id: COG2386

COG function: function code O; ABC-type transport system involved in cytochrome c biogenesis, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CcmB/CycW/HelB family [H]

Homologues:

Organism=Escherichia coli, GI1788528, Length=208, Percent_Identity=47.5961538461538, Blast_Score=125, Evalue=2e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003544 [H]

Pfam domain/function: PF03379 CcmB [H]

EC number: NA

Molecular weight: Translated: 22331; Mature: 22331

Theoretical pI: Translated: 5.80; Mature: 5.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRAVLALIARDLRLAGRVGGSGALSLVFFLMIVALVPFALGPDLNLLSRIGPAILWLAA
CHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
VLATLIGLDRLFQADEEDGSLDLMTAAPVPLELVVLGKVAAHWLTTGLPLALAAPLFGLL
HHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
VALDGTAMGATSLTLLAGTPALSFIGAVGAALTASIRRGGLILAVLVLPLMIPTLIFGVS
HHHCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
AAQAASGGTVPFLVPLAVLAALTLIAAVVGTLAAAAALRWPE
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MIRAVLALIARDLRLAGRVGGSGALSLVFFLMIVALVPFALGPDLNLLSRIGPAILWLAA
CHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
VLATLIGLDRLFQADEEDGSLDLMTAAPVPLELVVLGKVAAHWLTTGLPLALAAPLFGLL
HHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
VALDGTAMGATSLTLLAGTPALSFIGAVGAALTASIRRGGLILAVLVLPLMIPTLIFGVS
HHHCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
AAQAASGGTVPFLVPLAVLAALTLIAAVVGTLAAAAALRWPE
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1850420; 12597275 [H]