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The map label for this gene is atoS [H]

Identifier: 170752027

GI number: 170752027

Start: 5989118

End: 5991160

Strand: Reverse

Name: atoS [H]

Synonym: Mrad2831_5659

Alternate gene names: 170752027

Gene position: 5991160-5989118 (Counterclockwise)

Preceding gene: 170752028

Following gene: 170752026

Centisome position: 98.57

GC content: 69.41

Gene sequence:

>2043_bases
ATGACGGCGCCGCGCCCGCTCGCCTCCCCGCCGGCCGCGGCAGCGCCGCCGCGCTGGTTCCGCCTGCCGCTCGCGGGGAA
GTTCGCGGTGGCCTTCGTGGGCCTCGTCAGCCTGGTGCTGCTCATCAACGGCGCCGTCGACCTGACGCTGAACTATCAGG
ACGCCAAGCGGACCGCGATCGAGACGCAGCGCACCAAGGCGCGCGCCGCCGCCGAACGCGTCGACGCCTTCCTGTCCTCG
ATCGAGAGCCAGATCGGCTGGACGACCCGGGCCGAGTGGCGGCGGGTCTCCCCCGAGCAGCAGCGCTACGACTTCATCCG
CCTGCTGCGCCAGGCACCGGCCATCACGGAGGTGGCGTACCTCGATCCGGCCGGGAAGGAGCAGCTGCGCGTCTCGCGGC
TGGAGCCCGACGCCGTCGCCAGCGGCAAGGATTTCTCGGCCTCGCCGCGCTTCACCCAGGCGCTCGCCCAGAGGACCTGG
TTCGGCCCGGTCTATTTCCGGCGCGGCTCCGAGCCGTACATGACCGTCTCGGTGGCCCATGCCGGACGCGACCCCGGCGT
GACCGTCGCGGAAGTCAATCTGAAGCTGATCTGGGACGTGGTCAGCGCGATCAATGTCGGCGAGCACGGCTACGCCTTCG
TGACCACGGCGACCGGGCGGCTGATCGCGCACCCGGATCTGAGCCTCGTCCTGCGCGACACCGACCTGTCGGGTCTGGCC
GAGGTGGCGGCGGCCCTGCCCGGCTCCCGCATGGCGGGTCAGGACTACGAGATCACCACCGGCCTCGACGGCGGCTGGGT
GCTGGCGGCCCATGCCACGATCCCGCGGGTCGACTGGATCGTCTTCGTGCAGGAATCGCTGCGCGACGCCATGGGCCCCG
CCCTCGAATCCGTGATCCAGACCACATCGCTGATGGGTCTCGGCGTGCTGCTCGCAGCGGTGGCGGGAACCTTCCTGGCG
CGGCGCATGGTCGTGCCCATCCGCGAGCTCGAGGATGGGGCGGAGCGGTTCGGCGCGGGCGACCTGTCCGAGCGAATCGT
GATCCGCACCGGCGACGAGATAGAGACCCTCGCGCACCGGTTCAACACGATGGCGAGCCGGGTTCAGGATTCCTACGAGA
CGCTCGAGGCCAAGGTGGAGGAGCGGACCCGCGACCTCAACCGCTCGCTCGACGATCTCCAGCGGGCGCAGAGCCGGCTC
GTCCAGTCCGAGAAGCTCGCCTCGCTGGGACAGCTCACCGCCGGCATCGCCCACGAGATCAAGAACCCGCTGAACTTCGT
CAACAACTTCGCGTCGCTCTCGAACGAGCTGGTGGACGAGCTTCGCGAGGTGCTCGAACCGGCGGCCCTCGATCCGGACA
CGCGCGCGGAGGTCGAGGAGCTCGCCGGCCTGCTCAAGGGCAATCTCGAGAAGGTCGTCCAGCACGGCAAGCGCGCGGAC
TCGATCGTCAAGAACATGCTGCTGCACTCGCGCACCGGATCCGGCGAGCATCGACCGGTCGAGGTCAACGGGCTGGTCGA
GGAGAGCCTGAATCTTGCCTATCACGGGGCCCGCGCGGCGAAACCGAGCTTCAACGTGACCCTCGTGCGCGATTACGATC
CGGCGTCCGGTCTCGCCGACCTCTACCCCCAGGAGATCACGCGGGTCCTTCTGAACCTGATGTCGAACGGCTTCTACGCC
ACCGAGAAGCGGGCCGCCGACGGTGATCCCGGCTACGAACCGACGCTGTCGGTCGCGACCCGGGACCGGGGCGACAGCGT
CGAGATCCGCGTGCGCGACAACGGCACCGGCATCCCCGACAGCGTCAGAGCCAAGATGTTCGACCCGTTCTTCACCACCA
AGCCGGCGGGCGAGGGAACGGGGCTCGGCCTGTCGCTGAGCCACGACATCGTGGTCAAGCAGCACGGCGGGACGGTTGAC
GTCGCCTCGGAACCGGGTGCCTTCACGGAATTCATCATCACCCTGCCGCGCCAGAGTGTTACGCCGGCCGCGCCGCCTCG
GCCGGCGACCGAGACGGCGGCCGAGACCGAGAGCCAGCCATGA

Upstream 100 bases:

>100_bases
CGCCCACGAAGTTCGACTTCATCGTGAATTTGAAGACGGCCCGCACCATGGGCGTGACCATCTCGTCGGCGCTCCTCGCC
CAGGCGGACGAGATCGTCGA

Downstream 100 bases:

>100_bases
ACGTCCTGATCCTCGTCGTCGATGACGAACCCGACGTCACAGACCTGTTCCGGCAGCAGTTCCGCCGCGAGCTGCGCGCC
GGACGCTTCGCGATGGCCTT

Product: integral membrane sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 680; Mature: 679

Protein sequence:

>680_residues
MTAPRPLASPPAAAAPPRWFRLPLAGKFAVAFVGLVSLVLLINGAVDLTLNYQDAKRTAIETQRTKARAAAERVDAFLSS
IESQIGWTTRAEWRRVSPEQQRYDFIRLLRQAPAITEVAYLDPAGKEQLRVSRLEPDAVASGKDFSASPRFTQALAQRTW
FGPVYFRRGSEPYMTVSVAHAGRDPGVTVAEVNLKLIWDVVSAINVGEHGYAFVTTATGRLIAHPDLSLVLRDTDLSGLA
EVAAALPGSRMAGQDYEITTGLDGGWVLAAHATIPRVDWIVFVQESLRDAMGPALESVIQTTSLMGLGVLLAAVAGTFLA
RRMVVPIRELEDGAERFGAGDLSERIVIRTGDEIETLAHRFNTMASRVQDSYETLEAKVEERTRDLNRSLDDLQRAQSRL
VQSEKLASLGQLTAGIAHEIKNPLNFVNNFASLSNELVDELREVLEPAALDPDTRAEVEELAGLLKGNLEKVVQHGKRAD
SIVKNMLLHSRTGSGEHRPVEVNGLVEESLNLAYHGARAAKPSFNVTLVRDYDPASGLADLYPQEITRVLLNLMSNGFYA
TEKRAADGDPGYEPTLSVATRDRGDSVEIRVRDNGTGIPDSVRAKMFDPFFTTKPAGEGTGLGLSLSHDIVVKQHGGTVD
VASEPGAFTEFIITLPRQSVTPAAPPRPATETAAETESQP

Sequences:

>Translated_680_residues
MTAPRPLASPPAAAAPPRWFRLPLAGKFAVAFVGLVSLVLLINGAVDLTLNYQDAKRTAIETQRTKARAAAERVDAFLSS
IESQIGWTTRAEWRRVSPEQQRYDFIRLLRQAPAITEVAYLDPAGKEQLRVSRLEPDAVASGKDFSASPRFTQALAQRTW
FGPVYFRRGSEPYMTVSVAHAGRDPGVTVAEVNLKLIWDVVSAINVGEHGYAFVTTATGRLIAHPDLSLVLRDTDLSGLA
EVAAALPGSRMAGQDYEITTGLDGGWVLAAHATIPRVDWIVFVQESLRDAMGPALESVIQTTSLMGLGVLLAAVAGTFLA
RRMVVPIRELEDGAERFGAGDLSERIVIRTGDEIETLAHRFNTMASRVQDSYETLEAKVEERTRDLNRSLDDLQRAQSRL
VQSEKLASLGQLTAGIAHEIKNPLNFVNNFASLSNELVDELREVLEPAALDPDTRAEVEELAGLLKGNLEKVVQHGKRAD
SIVKNMLLHSRTGSGEHRPVEVNGLVEESLNLAYHGARAAKPSFNVTLVRDYDPASGLADLYPQEITRVLLNLMSNGFYA
TEKRAADGDPGYEPTLSVATRDRGDSVEIRVRDNGTGIPDSVRAKMFDPFFTTKPAGEGTGLGLSLSHDIVVKQHGGTVD
VASEPGAFTEFIITLPRQSVTPAAPPRPATETAAETESQP
>Mature_679_residues
TAPRPLASPPAAAAPPRWFRLPLAGKFAVAFVGLVSLVLLINGAVDLTLNYQDAKRTAIETQRTKARAAAERVDAFLSSI
ESQIGWTTRAEWRRVSPEQQRYDFIRLLRQAPAITEVAYLDPAGKEQLRVSRLEPDAVASGKDFSASPRFTQALAQRTWF
GPVYFRRGSEPYMTVSVAHAGRDPGVTVAEVNLKLIWDVVSAINVGEHGYAFVTTATGRLIAHPDLSLVLRDTDLSGLAE
VAAALPGSRMAGQDYEITTGLDGGWVLAAHATIPRVDWIVFVQESLRDAMGPALESVIQTTSLMGLGVLLAAVAGTFLAR
RMVVPIRELEDGAERFGAGDLSERIVIRTGDEIETLAHRFNTMASRVQDSYETLEAKVEERTRDLNRSLDDLQRAQSRLV
QSEKLASLGQLTAGIAHEIKNPLNFVNNFASLSNELVDELREVLEPAALDPDTRAEVEELAGLLKGNLEKVVQHGKRADS
IVKNMLLHSRTGSGEHRPVEVNGLVEESLNLAYHGARAAKPSFNVTLVRDYDPASGLADLYPQEITRVLLNLMSNGFYAT
EKRAADGDPGYEPTLSVATRDRGDSVEIRVRDNGTGIPDSVRAKMFDPFFTTKPAGEGTGLGLSLSHDIVVKQHGGTVDV
ASEPGAFTEFIITLPRQSVTPAAPPRPATETAAETESQP

Specific function: Member of the two-component regulatory system AtoS/AtoC; may activate AtoC by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=264, Percent_Identity=31.8181818181818, Blast_Score=117, Evalue=3e-27,
Organism=Escherichia coli, GI1790436, Length=269, Percent_Identity=33.0855018587361, Blast_Score=109, Evalue=5e-25,
Organism=Escherichia coli, GI1789149, Length=374, Percent_Identity=21.9251336898396, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI87081816, Length=377, Percent_Identity=24.9336870026525, Blast_Score=76, Evalue=6e-15,
Organism=Escherichia coli, GI1790300, Length=312, Percent_Identity=29.4871794871795, Blast_Score=74, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 73820; Mature: 73689

Theoretical pI: Translated: 5.27; Mature: 5.27

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAPRPLASPPAAAAPPRWFRLPLAGKFAVAFVGLVSLVLLINGAVDLTLNYQDAKRTAI
CCCCCCCCCCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHH
ETQRTKARAAAERVDAFLSSIESQIGWTTRAEWRRVSPEQQRYDFIRLLRQAPAITEVAY
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCHHHHHHHHHHHHHCCCHHEEEE
LDPAGKEQLRVSRLEPDAVASGKDFSASPRFTQALAQRTWFGPVYFRRGSEPYMTVSVAH
CCCCCHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCHHEECCCCCEEEEEEEE
AGRDPGVTVAEVNLKLIWDVVSAINVGEHGYAFVTTATGRLIAHPDLSLVLRDTDLSGLA
CCCCCCCEEEEEHHHHHHHHHHHHCCCCCCEEEEEECCCCEEECCCCEEEEECCCHHHHH
EVAAALPGSRMAGQDYEITTGLDGGWVLAAHATIPRVDWIVFVQESLRDAMGPALESVIQ
HHHHHCCCCCCCCCCEEEEECCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
TTSLMGLGVLLAAVAGTFLARRMVVPIRELEDGAERFGAGDLSERIVIRTGDEIETLAHR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCHHHHHHHH
FNTMASRVQDSYETLEAKVEERTRDLNRSLDDLQRAQSRLVQSEKLASLGQLTAGIAHEI
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KNPLNFVNNFASLSNELVDELREVLEPAALDPDTRAEVEELAGLLKGNLEKVVQHGKRAD
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCHHHHHHCCCHHH
SIVKNMLLHSRTGSGEHRPVEVNGLVEESLNLAYHGARAAKPSFNVTLVRDYDPASGLAD
HHHHHHHHHCCCCCCCCCCEEECCHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCHHH
LYPQEITRVLLNLMSNGFYATEKRAADGDPGYEPTLSVATRDRGDSVEIRVRDNGTGIPD
CCHHHHHHHHHHHHHCCCEEECCCCCCCCCCCCCCEEEEECCCCCEEEEEECCCCCCCCH
SVRAKMFDPFFTTKPAGEGTGLGLSLSHDIVVKQHGGTVDVASEPGAFTEFIITLPRQSV
HHHHHHCCCCCCCCCCCCCCCCEEEECCCEEEEECCCEEEECCCCCCHHHHHEECCCCCC
TPAAPPRPATETAAETESQP
CCCCCCCCCCHHHHHCCCCC
>Mature Secondary Structure 
TAPRPLASPPAAAAPPRWFRLPLAGKFAVAFVGLVSLVLLINGAVDLTLNYQDAKRTAI
CCCCCCCCCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHH
ETQRTKARAAAERVDAFLSSIESQIGWTTRAEWRRVSPEQQRYDFIRLLRQAPAITEVAY
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCHHHHHHHHHHHHHCCCHHEEEE
LDPAGKEQLRVSRLEPDAVASGKDFSASPRFTQALAQRTWFGPVYFRRGSEPYMTVSVAH
CCCCCHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCHHEECCCCCEEEEEEEE
AGRDPGVTVAEVNLKLIWDVVSAINVGEHGYAFVTTATGRLIAHPDLSLVLRDTDLSGLA
CCCCCCCEEEEEHHHHHHHHHHHHCCCCCCEEEEEECCCCEEECCCCEEEEECCCHHHHH
EVAAALPGSRMAGQDYEITTGLDGGWVLAAHATIPRVDWIVFVQESLRDAMGPALESVIQ
HHHHHCCCCCCCCCCEEEEECCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
TTSLMGLGVLLAAVAGTFLARRMVVPIRELEDGAERFGAGDLSERIVIRTGDEIETLAHR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCHHHHHHHH
FNTMASRVQDSYETLEAKVEERTRDLNRSLDDLQRAQSRLVQSEKLASLGQLTAGIAHEI
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KNPLNFVNNFASLSNELVDELREVLEPAALDPDTRAEVEELAGLLKGNLEKVVQHGKRAD
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCHHHHHHCCCHHH
SIVKNMLLHSRTGSGEHRPVEVNGLVEESLNLAYHGARAAKPSFNVTLVRDYDPASGLAD
HHHHHHHHHCCCCCCCCCCEEECCHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCHHH
LYPQEITRVLLNLMSNGFYATEKRAADGDPGYEPTLSVATRDRGDSVEIRVRDNGTGIPD
CCHHHHHHHHHHHHHCCCEEECCCCCCCCCCCCCCEEEEECCCCCEEEEEECCCCCCCCH
SVRAKMFDPFFTTKPAGEGTGLGLSLSHDIVVKQHGGTVDVASEPGAFTEFIITLPRQSV
HHHHHHCCCCCCCCCCCCCCCCEEEECCCEEEEECCCEEEECCCCCCHHHHHEECCCCCC
TPAAPPRPATETAAETESQP
CCCCCCCCCCHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8346225; 9097040; 9278503 [H]