Click here to switch to the map view.

The map label for this gene is pilR [H]

Identifier: 170752026

GI number: 170752026

Start: 5988723

End: 5989121

Strand: Reverse

Name: pilR [H]

Synonym: Mrad2831_5658

Alternate gene names: 170752026

Gene position: 5989121-5988723 (Counterclockwise)

Preceding gene: 170752027

Following gene: 170752025

Centisome position: 98.54

GC content: 68.17

Gene sequence:

>399_bases
ATGAACGTCCTGATCCTCGTCGTCGATGACGAACCCGACGTCACAGACCTGTTCCGGCAGCAGTTCCGCCGCGAGCTGCG
CGCCGGACGCTTCGCGATGGCCTTCGCGCACTCGGCGGCGGAAGCCCTGGAGCGGATCAACGGCGCCAACGAGCCGAGCC
TGATCCTGATGCTGTCGGACATCAACATGCCCGGGATGACCGGCCTCGAATTGCTGCCCCTGGTGCGCGCCGCGCGCCCC
GACGTGCCGGTGATCATGATCACAGCCTACGGCGACGCCGAGACGCGCGAGAAGGTCCGCGCCGCCGGCGCCGTGGGCCT
GATCACCAAGCCGATCGACTTCGCCGTGCTGAAGGCCGAGATCGATCGCCGGCTGTCCGCCTTCGCGGGGACCGAATGA

Upstream 100 bases:

>100_bases
CCTTCACGGAATTCATCATCACCCTGCCGCGCCAGAGTGTTACGCCGGCCGCGCCGCCTCGGCCGGCGACCGAGACGGCG
GCCGAGACCGAGAGCCAGCC

Downstream 100 bases:

>100_bases
CCCCCGGCGCCCCGAACGCCAAGATCCTGGTCGTCGACGACGAGCCGGATCTCGAGGCGCTGATCACCCAGAAATTCCGC
CGCCAGATCCGCCAGGGCCT

Product: response regulator receiver protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 132; Mature: 132

Protein sequence:

>132_residues
MNVLILVVDDEPDVTDLFRQQFRRELRAGRFAMAFAHSAAEALERINGANEPSLILMLSDINMPGMTGLELLPLVRAARP
DVPVIMITAYGDAETREKVRAAGAVGLITKPIDFAVLKAEIDRRLSAFAGTE

Sequences:

>Translated_132_residues
MNVLILVVDDEPDVTDLFRQQFRRELRAGRFAMAFAHSAAEALERINGANEPSLILMLSDINMPGMTGLELLPLVRAARP
DVPVIMITAYGDAETREKVRAAGAVGLITKPIDFAVLKAEIDRRLSAFAGTE
>Mature_132_residues
MNVLILVVDDEPDVTDLFRQQFRRELRAGRFAMAFAHSAAEALERINGANEPSLILMLSDINMPGMTGLELLPLVRAARP
DVPVIMITAYGDAETREKVRAAGAVGLITKPIDFAVLKAEIDRRLSAFAGTE

Specific function: Member of the two-component regulatory system pilS/pilR that regulates the expression of type 4 fimbriae. When activated by pilS it acts in conjunction with sigma-54 as a transcriptional activator [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1790437, Length=125, Percent_Identity=32.8, Blast_Score=66, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 14436; Mature: 14436

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVLILVVDDEPDVTDLFRQQFRRELRAGRFAMAFAHSAAEALERINGANEPSLILMLSD
CCEEEEEECCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEC
INMPGMTGLELLPLVRAARPDVPVIMITAYGDAETREKVRAAGAVGLITKPIDFAVLKAE
CCCCCCCCHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHCCCCCEEECCHHHHHHHHH
IDRRLSAFAGTE
HHHHHHHHCCCC
>Mature Secondary Structure
MNVLILVVDDEPDVTDLFRQQFRRELRAGRFAMAFAHSAAEALERINGANEPSLILMLSD
CCEEEEEECCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEC
INMPGMTGLELLPLVRAARPDVPVIMITAYGDAETREKVRAAGAVGLITKPIDFAVLKAE
CCCCCCCCHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHCCCCCEEECCHHHHHHHHH
IDRRLSAFAGTE
HHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1317379; 8097014; 7911557; 10984043 [H]