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The map label for this gene is actP [H]

Identifier: 170751964

GI number: 170751964

Start: 5923098

End: 5924780

Strand: Reverse

Name: actP [H]

Synonym: Mrad2831_5596

Alternate gene names: 170751964

Gene position: 5924780-5923098 (Counterclockwise)

Preceding gene: 170751965

Following gene: 170751963

Centisome position: 97.48

GC content: 67.74

Gene sequence:

>1683_bases
ATGAACCGCCTCCTTCTCGGCCTGACGCTCGCCACGATCGTCGCGAGCGCCGCCTACGCGGCCGGCCCGGATCTCGGCGC
CGTCGCGCAATCGGCCACGAACTGGCCGGCCATCCTGATGTTCCTGTTCTTCGTGCTGCTGACGCTCGGCATCACCTACC
GGGCCGCCAAGGGCACCAAGTCTGCCGCCGACTTCTACGCGGCGGGCGGCGGCATCTCGGCAGGGACGAACTCCCTGGCG
ATCGCCGGCGACTACATGTCGGCGGCCTCGTTCCTCGGCATCTCCGGCCTCGTCTACACCTCGGGCTTCGACGGGCTGAT
CTACTCGACGGGCTTCCTGGTCGGCTGGCCCATCGTGCTGTTCCTGATCGCGGAGCGCCTGCGCAACCTCGGCAAGTTCA
CCTTCGCCGACGTGGCGAGCTTCCGCCTCGACCAGACCGCGATCCGCATCATCTCGGCGGTGGGCACCCTGGTGGTGGTG
GCCTTCTACCTGATCGCCCAGATGGTCGGCGCGGGGAAGTTGATCCAGCTCCTGTTCGGCCTGCCCTACCTCTACGCGGT
GATCATCGTCGGCGTCCTGATGATCGTCTACGTCGCCTTCGGCGGCATGAAGGCGACCACCTGGGTGCAGGTGATCAAGG
CCTGCCTGCTGCTCGGCGGCGCGACCTTCATGGCCGGCGCGGTGCTGCTGAAGTACGGCTTCAACCCGGAAATGCTGTTC
GCCAGCGCCGTTCAGGTCCACCCGAAGGGCGACGCCATCATGGCGCCGGGAGGCCTCGTGTCGAACCCGGTCGAGGCGAT
CTCGCTCGGCGTCGGCCTGATGTTCGGCACCGCCGGCCTGCCGCACATCCTGATGCGGTTCTTCACGGTCTCGGACGCCC
AGGCCGCCCGCAAGTCGGTGTTCTACGCCACCGGCCTGATCGGCTACTTCTACATTTTGACCTTCATCATCGGCTTCGGC
GGCATCGCGCTGCTGATGTCGGACCCGGTCTACTTCAAGCTCGGTCCGGCCGGCGCGTTCGACAAGCTGAAGGACATGAT
CGGCGGCACCAACATGGTGGCGGTGAACCTCGCCAACGCGGTGGGCGGCCCGTACTTCCTGGGCTTCATCTCCGCCGTGG
CCTTCGCCACGATCCTCGCGGTCGTCGCCGGCCTGACGCTCGCCGGCGCTTCGGCGATCAGTCACGACCTCTACGCCCAG
GTGATCGCCCGCGGGCGGACCACCGAGAAGCACGAGGTCAACCTGTCGAAGATCTCGGCCGTGGTGATCGGCATCGTGGC
GATCTACCTCGGCTACGTGTTCGAGAACCAGAACGTCGCCTTCATGGTCGGCCTCGCCTTCGCGGTGGCGGCGAGCTGCA
ATTTCCCGGTGCTCGCCATGTCGATCCTGTGGCGGGGCACCACCACCTGGGGCGCGCTCGCCGGCGGCCTCGTCGGCCTG
CTCGCGGCGGTCATCATGGTGGTGCTGTCGAAGGCCGTGTGGGTGACGACGCTGGGCAACCCCGCCCCGCTCTTCCCCTA
CGACAACCCGGCGCTGTTCTCGATGCCGCTGGCCTTCGCGACGATCTGGGTCGTATCCCTCTTGGACAAGACCCGGCGCG
CGCAGCGCGAGCGGGCCGCCTTCGAGGCCCAGTACGTGCGTTCCGAGACGGGCATCGGGGCCGCCGGCGCGCACGCGCAC
TGA

Upstream 100 bases:

>100_bases
TCGTGATCCTGTTCGCCTTCGCGCTCACGGGGGTCTACGTCGCCCGGGCCAACACGCGCTTCGACGCGCTGAGCGAAGCC
CTGAAGCGGAGCGTGGCCCG

Downstream 100 bases:

>100_bases
CGACGATCCGACGGGTCTGACAGGCGGAGGGCGCGGCGCGAGCCGCGCCCTTCGTCGTTCCGGTGACAACTCGGTACGCG
CCCATGTTGATGAGGGTCTT

Product: SSS family solute/sodium (Na+) symporter

Products: NA

Alternate protein names: Acetate permease; Acetate transporter ActP [H]

Number of amino acids: Translated: 560; Mature: 560

Protein sequence:

>560_residues
MNRLLLGLTLATIVASAAYAAGPDLGAVAQSATNWPAILMFLFFVLLTLGITYRAAKGTKSAADFYAAGGGISAGTNSLA
IAGDYMSAASFLGISGLVYTSGFDGLIYSTGFLVGWPIVLFLIAERLRNLGKFTFADVASFRLDQTAIRIISAVGTLVVV
AFYLIAQMVGAGKLIQLLFGLPYLYAVIIVGVLMIVYVAFGGMKATTWVQVIKACLLLGGATFMAGAVLLKYGFNPEMLF
ASAVQVHPKGDAIMAPGGLVSNPVEAISLGVGLMFGTAGLPHILMRFFTVSDAQAARKSVFYATGLIGYFYILTFIIGFG
GIALLMSDPVYFKLGPAGAFDKLKDMIGGTNMVAVNLANAVGGPYFLGFISAVAFATILAVVAGLTLAGASAISHDLYAQ
VIARGRTTEKHEVNLSKISAVVIGIVAIYLGYVFENQNVAFMVGLAFAVAASCNFPVLAMSILWRGTTTWGALAGGLVGL
LAAVIMVVLSKAVWVTTLGNPAPLFPYDNPALFSMPLAFATIWVVSLLDKTRRAQRERAAFEAQYVRSETGIGAAGAHAH

Sequences:

>Translated_560_residues
MNRLLLGLTLATIVASAAYAAGPDLGAVAQSATNWPAILMFLFFVLLTLGITYRAAKGTKSAADFYAAGGGISAGTNSLA
IAGDYMSAASFLGISGLVYTSGFDGLIYSTGFLVGWPIVLFLIAERLRNLGKFTFADVASFRLDQTAIRIISAVGTLVVV
AFYLIAQMVGAGKLIQLLFGLPYLYAVIIVGVLMIVYVAFGGMKATTWVQVIKACLLLGGATFMAGAVLLKYGFNPEMLF
ASAVQVHPKGDAIMAPGGLVSNPVEAISLGVGLMFGTAGLPHILMRFFTVSDAQAARKSVFYATGLIGYFYILTFIIGFG
GIALLMSDPVYFKLGPAGAFDKLKDMIGGTNMVAVNLANAVGGPYFLGFISAVAFATILAVVAGLTLAGASAISHDLYAQ
VIARGRTTEKHEVNLSKISAVVIGIVAIYLGYVFENQNVAFMVGLAFAVAASCNFPVLAMSILWRGTTTWGALAGGLVGL
LAAVIMVVLSKAVWVTTLGNPAPLFPYDNPALFSMPLAFATIWVVSLLDKTRRAQRERAAFEAQYVRSETGIGAAGAHAH
>Mature_560_residues
MNRLLLGLTLATIVASAAYAAGPDLGAVAQSATNWPAILMFLFFVLLTLGITYRAAKGTKSAADFYAAGGGISAGTNSLA
IAGDYMSAASFLGISGLVYTSGFDGLIYSTGFLVGWPIVLFLIAERLRNLGKFTFADVASFRLDQTAIRIISAVGTLVVV
AFYLIAQMVGAGKLIQLLFGLPYLYAVIIVGVLMIVYVAFGGMKATTWVQVIKACLLLGGATFMAGAVLLKYGFNPEMLF
ASAVQVHPKGDAIMAPGGLVSNPVEAISLGVGLMFGTAGLPHILMRFFTVSDAQAARKSVFYATGLIGYFYILTFIIGFG
GIALLMSDPVYFKLGPAGAFDKLKDMIGGTNMVAVNLANAVGGPYFLGFISAVAFATILAVVAGLTLAGASAISHDLYAQ
VIARGRTTEKHEVNLSKISAVVIGIVAIYLGYVFENQNVAFMVGLAFAVAASCNFPVLAMSILWRGTTTWGALAGGLVGL
LAAVIMVVLSKAVWVTTLGNPAPLFPYDNPALFSMPLAFATIWVVSLLDKTRRAQRERAAFEAQYVRSETGIGAAGAHAH

Specific function: Transports acetate [H]

COG id: COG4147

COG function: function code R; Predicted symporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family [H]

Homologues:

Organism=Homo sapiens, GI310128183, Length=475, Percent_Identity=22.7368421052632, Blast_Score=91, Evalue=2e-18,
Organism=Escherichia coli, GI1790503, Length=560, Percent_Identity=63.2142857142857, Blast_Score=679, Evalue=0.0,
Organism=Escherichia coli, GI1787251, Length=464, Percent_Identity=26.0775862068966, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI87082237, Length=364, Percent_Identity=24.1758241758242, Blast_Score=69, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014083
- InterPro:   IPR001734
- InterPro:   IPR018212
- InterPro:   IPR019900 [H]

Pfam domain/function: PF00474 SSF [H]

EC number: NA

Molecular weight: Translated: 58621; Mature: 58621

Theoretical pI: Translated: 9.62; Mature: 9.62

Prosite motif: PS00456 NA_SOLUT_SYMP_1 ; PS50283 NA_SOLUT_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure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HHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA