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The map label for this gene is gpmA [H]

Identifier: 170751644

GI number: 170751644

Start: 5589849

End: 5590526

Strand: Reverse

Name: gpmA [H]

Synonym: Mrad2831_5270

Alternate gene names: 170751644

Gene position: 5590526-5589849 (Counterclockwise)

Preceding gene: 170751645

Following gene: 170751643

Centisome position: 91.98

GC content: 66.67

Gene sequence:

>678_bases
ATGCGACCGACGCGAAAGTGCGTTGCCTTGGGAGACAGAGTGATTCACGATCGCAAAGCCCCAATCACGCGACGTCTCGT
GCTGGTCCGGCATGGCCAGAGCGTAGCCAACCGATCCGGTCTGTTCACGGGATTGCTGGACTCGCCCTTGACCGAGCAGG
GTCGGATAGAAGCCGTGGCAGCCGGGCGGCGTTTGGCCGAGCGCAGCTGGCGCTTTTCCGATGCCTTCACCTCGACGCTG
ACGCGGGCCGTCGTGAGCGGCCGGCTTATCCTCGATACGCTCGGGCAACCCGGATTAATCCCTCAACGCTTCGCCGCGCT
CGACGAGCGAGACTACGGCGACCTCAGCGGGCTCGACAAGACCGCCGCCGATGCGCGCTGGGGGGCGGAGCGGATCGAGA
CCTGGCGGCGCTCCTACGCCGAGGCGCCGCCGAACGGTGAGAGCCTGCGCGATACCGTCGCCCGCATCGTGCCATGCTAC
CTCCGATCCATCCTACCGGCGGTCATGGGCGGGGACGTGCTCGTCGTCGCCCACGGTAATTGCCTGCGGGCGCTCGTTAT
GGCGCTCGACGACCTCAGCCCGGCGGAGGTCGAGCACCTCGAACTCGCGACGGGCTCCGTCAGGATCTATGAGTTTGCTG
CGGACACGACGATCGAGGCCCGCTGGATCGACGGTTGA

Upstream 100 bases:

>100_bases
CTAAAGCGGACCTAGGCTGAATCGCCGTCTCCGGATGGACGGTCCAACCCATCTCAGGGTCGAAGTTCGTAAAAGCCGGA
TGCCGTTTTCATCAGAGGCG

Downstream 100 bases:

>100_bases
ATCCGCCTGTAGGCCCCCAAGAATGGGTCGCCTCACGCTTCGAAGGGATCCCCATTTGATCTAATTAAGTGATGGGAATT
ATCTAATCATTCCGTTGGAG

Product: phosphoglycerate mutase

Products: NA

Alternate protein names: BPG-dependent PGAM; PGAM; Phosphoglyceromutase; dPGM [H]

Number of amino acids: Translated: 225; Mature: 225

Protein sequence:

>225_residues
MRPTRKCVALGDRVIHDRKAPITRRLVLVRHGQSVANRSGLFTGLLDSPLTEQGRIEAVAAGRRLAERSWRFSDAFTSTL
TRAVVSGRLILDTLGQPGLIPQRFAALDERDYGDLSGLDKTAADARWGAERIETWRRSYAEAPPNGESLRDTVARIVPCY
LRSILPAVMGGDVLVVAHGNCLRALVMALDDLSPAEVEHLELATGSVRIYEFAADTTIEARWIDG

Sequences:

>Translated_225_residues
MRPTRKCVALGDRVIHDRKAPITRRLVLVRHGQSVANRSGLFTGLLDSPLTEQGRIEAVAAGRRLAERSWRFSDAFTSTL
TRAVVSGRLILDTLGQPGLIPQRFAALDERDYGDLSGLDKTAADARWGAERIETWRRSYAEAPPNGESLRDTVARIVPCY
LRSILPAVMGGDVLVVAHGNCLRALVMALDDLSPAEVEHLELATGSVRIYEFAADTTIEARWIDG
>Mature_225_residues
MRPTRKCVALGDRVIHDRKAPITRRLVLVRHGQSVANRSGLFTGLLDSPLTEQGRIEAVAAGRRLAERSWRFSDAFTSTL
TRAVVSGRLILDTLGQPGLIPQRFAALDERDYGDLSGLDKTAADARWGAERIETWRRSYAEAPPNGESLRDTVARIVPCY
LRSILPAVMGGDVLVVAHGNCLRALVMALDDLSPAEVEHLELATGSVRIYEFAADTTIEARWIDG

Specific function: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate [H]

COG id: COG0588

COG function: function code G; Phosphoglycerate mutase 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily [H]

Homologues:

Organism=Homo sapiens, GI50593010, Length=221, Percent_Identity=34.3891402714932, Blast_Score=124, Evalue=7e-29,
Organism=Homo sapiens, GI4505753, Length=216, Percent_Identity=34.2592592592593, Blast_Score=117, Evalue=7e-27,
Organism=Homo sapiens, GI4502445, Length=211, Percent_Identity=30.8056872037915, Blast_Score=108, Evalue=4e-24,
Organism=Homo sapiens, GI40353764, Length=211, Percent_Identity=30.8056872037915, Blast_Score=108, Evalue=4e-24,
Organism=Homo sapiens, GI71274132, Length=216, Percent_Identity=31.0185185185185, Blast_Score=103, Evalue=1e-22,
Organism=Homo sapiens, GI310129614, Length=166, Percent_Identity=31.9277108433735, Blast_Score=84, Evalue=1e-16,
Organism=Escherichia coli, GI1786970, Length=214, Percent_Identity=38.3177570093458, Blast_Score=143, Evalue=1e-35,
Organism=Saccharomyces cerevisiae, GI6322697, Length=214, Percent_Identity=33.1775700934579, Blast_Score=110, Evalue=1e-25,
Organism=Drosophila melanogaster, GI85725270, Length=217, Percent_Identity=35.9447004608295, Blast_Score=127, Evalue=8e-30,
Organism=Drosophila melanogaster, GI85725272, Length=217, Percent_Identity=35.9447004608295, Blast_Score=127, Evalue=8e-30,
Organism=Drosophila melanogaster, GI24650981, Length=217, Percent_Identity=35.9447004608295, Blast_Score=127, Evalue=8e-30,
Organism=Drosophila melanogaster, GI24646216, Length=217, Percent_Identity=34.1013824884793, Blast_Score=120, Evalue=7e-28,
Organism=Drosophila melanogaster, GI24648979, Length=222, Percent_Identity=30.1801801801802, Blast_Score=95, Evalue=3e-20,
Organism=Drosophila melanogaster, GI28571815, Length=222, Percent_Identity=30.1801801801802, Blast_Score=95, Evalue=4e-20,
Organism=Drosophila melanogaster, GI28571817, Length=222, Percent_Identity=30.1801801801802, Blast_Score=95, Evalue=4e-20,

Paralogues:

None

Copy number: 960 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013078
- InterPro:   IPR001345
- InterPro:   IPR005952 [H]

Pfam domain/function: PF00300 PGAM [H]

EC number: =5.4.2.1 [H]

Molecular weight: Translated: 24717; Mature: 24717

Theoretical pI: Translated: 8.08; Mature: 8.08

Prosite motif: PS00175 PG_MUTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPTRKCVALGDRVIHDRKAPITRRLVLVRHGQSVANRSGLFTGLLDSPLTEQGRIEAVA
CCCHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHCCCCHHHHCCCCCCCCCCHHHH
AGRRLAERSWRFSDAFTSTLTRAVVSGRLILDTLGQPGLIPQRFAALDERDYGDLSGLDK
HHHHHHHHHCCHHHHHHHHHHHHHHHCHHHEECCCCCCCCHHHHHHHCCCCCCCCCCCCH
TAADARWGAERIETWRRSYAEAPPNGESLRDTVARIVPCYLRSILPAVMGGDVLVVAHGN
HHHHHHCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCH
CLRALVMALDDLSPAEVEHLELATGSVRIYEFAADTTIEARWIDG
HHHHHHHHHHCCCCHHHHHHEECCCCEEEEEEECCCEEEEEECCC
>Mature Secondary Structure
MRPTRKCVALGDRVIHDRKAPITRRLVLVRHGQSVANRSGLFTGLLDSPLTEQGRIEAVA
CCCHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHCCCCHHHHCCCCCCCCCCHHHH
AGRRLAERSWRFSDAFTSTLTRAVVSGRLILDTLGQPGLIPQRFAALDERDYGDLSGLDK
HHHHHHHHHCCHHHHHHHHHHHHHHHCHHHEECCCCCCCCHHHHHHHCCCCCCCCCCCCH
TAADARWGAERIETWRRSYAEAPPNGESLRDTVARIVPCYLRSILPAVMGGDVLVVAHGN
HHHHHHCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCH
CLRALVMALDDLSPAEVEHLELATGSVRIYEFAADTTIEARWIDG
HHHHHHHHHHCCCCHHHHHHEECCCCEEEEEEECCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA