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The map label for this gene is crp [C]

Identifier: 170751394

GI number: 170751394

Start: 5332888

End: 5333331

Strand: Direct

Name: crp [C]

Synonym: Mrad2831_5013

Alternate gene names: 170751394

Gene position: 5332888-5333331 (Clockwise)

Preceding gene: 170751392

Following gene: 170751396

Centisome position: 87.74

GC content: 70.5

Gene sequence:

>444_bases
ATGACCCTCGACACCGAGGTTTCCTCCCTGAAGCAGGTGCCGCTCTTCCGCGAGGTGGAGCCGGCGCGCCTGAAGCTCCT
CGCCTTCACCAGCGAGCGGGTCCATTTCGAGCCGGGGCAACGCTTCTTCGCCCGCGGCGACGTGGCGGATGCGGCCTACG
TGATCCTCTCGGGCACGGCGGAGGTCAGCATCGACGGTCCCGCCGGGCCGGTGCGGCTGGCGCTCCTCGGCCAGGACGCC
CTCGTCGGTGAGATGGGCATCCTGGCCGAGCAGCCCCGCTCCGCCACCGTGACGGCGCAATCCGCGGTGACCGCCCTGCG
CATCGACCGCGGCGTGTTCCTGGAACTCCTGGCACAGTTTCCGCAGATCAGCATCGCCCTGATGCGCGTGCTGGCGCTGC
GGCTGGAGCAGACCAATCAGGCGCTGGCCGAGAGCCGGGGCTGA

Upstream 100 bases:

>100_bases
GGCAGGCGCGGGGCTGGACAAGTGCCTGACGAACCGCATGGATAAGCGCGCCCGTCCGGCCCCGCCGTCCTGGGCGTGAG
ACCCGTCGCGGAGCCCCCGA

Downstream 100 bases:

>100_bases
TCATCCCGCGTAGGTGATGAACTCCAGGAGCGAGCCGTCCGGATCCCGGAAGTAGACGCTGATCCCCGCACCCGCGGCGC
CGTGCCGCTCCACCGGGCCG

Product: cyclic nucleotide-binding protein

Products: NA

Alternate protein names: Transcriptional Regulator; Transcriptional Regulator Protein

Number of amino acids: Translated: 147; Mature: 146

Protein sequence:

>147_residues
MTLDTEVSSLKQVPLFREVEPARLKLLAFTSERVHFEPGQRFFARGDVADAAYVILSGTAEVSIDGPAGPVRLALLGQDA
LVGEMGILAEQPRSATVTAQSAVTALRIDRGVFLELLAQFPQISIALMRVLALRLEQTNQALAESRG

Sequences:

>Translated_147_residues
MTLDTEVSSLKQVPLFREVEPARLKLLAFTSERVHFEPGQRFFARGDVADAAYVILSGTAEVSIDGPAGPVRLALLGQDA
LVGEMGILAEQPRSATVTAQSAVTALRIDRGVFLELLAQFPQISIALMRVLALRLEQTNQALAESRG
>Mature_146_residues
TLDTEVSSLKQVPLFREVEPARLKLLAFTSERVHFEPGQRFFARGDVADAAYVILSGTAEVSIDGPAGPVRLALLGQDAL
VGEMGILAEQPRSATVTAQSAVTALRIDRGVFLELLAQFPQISIALMRVLALRLEQTNQALAESRG

Specific function: This Protein Complexes With Cyclic AMP And Binds To Specific DNA Sites Near The Promoter To Regulate The Transcription Of Several Catabolite-Sensitive Operons. The Protein Induces A Severe Bend In The DNA. Acts As A Negative Regulator Of Its Own Synthesi

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 15860; Mature: 15728

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: PS00889 CNMP_BINDING_2 ; PS50042 CNMP_BINDING_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLDTEVSSLKQVPLFREVEPARLKLLAFTSERVHFEPGQRFFARGDVADAAYVILSGTA
CCCCCCHHHHHCCCCCCCCCHHHEEEEEEECCCEEECCCCEEEECCCCCCEEEEEEECCE
EVSIDGPAGPVRLALLGQDALVGEMGILAEQPRSATVTAQSAVTALRIDRGVFLELLAQF
EEEECCCCCCEEEEEECCCHHHCCCCHHCCCCCCCEEEHHHHHHHHHCCCHHHHHHHHHC
PQISIALMRVLALRLEQTNQALAESRG
CCHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TLDTEVSSLKQVPLFREVEPARLKLLAFTSERVHFEPGQRFFARGDVADAAYVILSGTA
CCCCCHHHHHCCCCCCCCCHHHEEEEEEECCCEEECCCCEEEECCCCCCEEEEEEECCE
EVSIDGPAGPVRLALLGQDALVGEMGILAEQPRSATVTAQSAVTALRIDRGVFLELLAQF
EEEECCCCCCEEEEEECCCHHHCCCCHHCCCCCCCEEEHHHHHHHHHCCCHHHHHHHHHC
PQISIALMRVLALRLEQTNQALAESRG
CCHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA