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The map label for this gene is cycK [H]

Identifier: 170751374

GI number: 170751374

Start: 5313667

End: 5315667

Strand: Direct

Name: cycK [H]

Synonym: Mrad2831_4993

Alternate gene names: 170751374

Gene position: 5313667-5315667 (Clockwise)

Preceding gene: 170751373

Following gene: 170751375

Centisome position: 87.43

GC content: 71.21

Gene sequence:

>2001_bases
ATGATCGTCGAGACCGGCCACTTCGCCCTCGCGCTCGCGCTGGCGATCTCCCTCGTCCAGGTGGTGATGCCGATCTGGGC
CGCCCGCTCGGGCGATCCGGCGCTCCGCCAGATCGCCTCGCAGGCGGCGCTCGGCGCGTTCGCCTGCGTGCTGTTCGCCT
TCGCGGCGCTGACCTACGCGCACGTCACCTCGGACTTCTCGGTCCAGAACGTCGTCGAGAACTCGCACACGCAGAAGCCG
CTGATCTACAAGATCTCGGGCGTCTGGGGGAACCACGAGGGCTCGATGCTCCTCTGGGTGCTGATCCTCACCCTGTTCGG
CGCCTGCGTGGCGGCCGCGAAGAACTCGGTGCCGCCGCGGCTGCGGGCCAGCACGCTCGGCGTGCAGGGGCTGATCACCT
TCGTGTTCGTGCTGTTCATCATCACGACCTCGAACCCGTTCACCCGGGTGATCCCGGCGCCGCTCGAGGGCAACGACCTC
AACCCGCTGTTGCAGGATCCCGGTCTCGCGATCCACCCGCCGCTCCTCTACGTCGGCTATGTCGGCTTCTCGATCAGCTT
CGCCTTCGCGGTGGCCGCGCTGATCGACGGGCGGATCGACGCCGTCTGGGCGCGGGCGGTGCGGCCCTGGACGCTGGCCG
CGTGGTGCTTCCTGACGCTCGGGATCGCGATGGGTTCCTACTGGGCCTATTACGAGCTCGGCTGGGGCGGCTGGTGGTTC
TGGGATCCGGTGGAGAACGCCTCGCTGATGCCGTGGATCGCCGGCACGGCGCTGCTGCACTCCACCGTGGTGATGGAGAA
GCGCGACGCCCTGAAGGTCTGGACGGTGCTGCTCGCCATCCTGACCTTCTCGCTCTCGCTGATCGGCACCTTCCTGGTCC
GCTCGGGCGTGATCACCTCGGTCCATTCCTTCGCCACGGACCCGACCCGCGGCGTCTTCATCCTGGCGATCCTGGTGCTG
TTCATCGGCGGCTCGCTGACGCTGTTCGCGTGGCGGGCGCCGCTGCTGCGGCAGGGCGGCCTGTTCGCGCCGATCTCTCG
CGAGGGGTCGCTCGTCCTGAACAACCTGTTCCTGGTGGCGGCCTGCGCCACCGTGCTGGTCGGCACCCTGTACCCGCTCG
TGCTGGAGATGCTGACGGGCGAGAAGATCACGGTCGGGCCGCCCTTCTTCAACTCCACCTTCGTCCCGCTGGCGATCCCG
CTCCTGCTGATCGTCCCCATGGGGCAGTCGCTCGCCTGGAAGCGCGGCGACGTGCTCGCCGCCGCCCAGCGCCTGTTCGC
CGCGCTGGCGGTCGCCCTGGTCGTCGGCTTCGGGGTGCTGGCGCTGACCTGGGGCGGGCCGGTCATGGCGCCGGTCGGGA
TCGGCCTCGGCGCCTACCTGCTGATCGGCTCCGCCCTGGAGATCGTCACCCGCGCCCGGGGCTACGGGGCGAGCCGCGCC
CGCTCCCTCGGCCAGATCGGCCGCCGCGCCGTCGGCCTGCCGCGCTCGGCCTGGGGCACCGCCATCGCTCATGCCGGGGT
CGGCGTCGTGGTGCTGGGCATCGCCGCGCAGGGCTGGGCGACCGAGGGGCTGGCGACCCTCAAGGCCGGCCAGAGCCTGG
CGACGGGACCCTACGTGGCGACCCTCGATCGCGTCGCGCCGCGCAAGGGACCGAACTACGAGGAGGCCGCCGCCTACCTG
ACCATCCGCACCCGCGGCGGCGACGAGGTCGGGCAGGTCGAGACCGGCAAGCGGTTCTACCCGAGCCGCAAGATGGCGGT
GACGGAATCGGGCCTGCTGACCGTCGGCGCCAGCCAGGTCTACGCGAGTCTCGGGGAGATCGGGCAGGACGGCGGCGTCG
GCCTGCGCCTCTACTACAAGCCGCTGGTCCTGCTGATCTGGCTCGGGGCGGTGGTGATGGCCGTGGGCGGCGGCCTGTCG
CTCACGGACCGGCGGATGCGCGTAGGCGTCCCCGCCAAGGCGAAGGCGCGGCCGCTCCCGGTCGCGGTGCCGGCCGAGTG
A

Upstream 100 bases:

>100_bases
CAGGAGGGCGGCCCGAACAGGGGCGGCCCGGCGCCGAAGCCCGCCACCGCGGCGGCGGACAGCACCCTCGGTCCCCGCAG
CGAGCGGTGAGGGAACCCGC

Downstream 100 bases:

>100_bases
TGGCGCGCCGCTCGCTCCGGCCCGCGCTGGCGGCGCTCGCCCTGCTGGCGTCGCTGCCGGCCCTCGCGGTGCAGCCCGAC
GAGGTGCTGAAGGATCCCGT

Product: cytochrome c-type biogenesis protein CcmF

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 666; Mature: 666

Protein sequence:

>666_residues
MIVETGHFALALALAISLVQVVMPIWAARSGDPALRQIASQAALGAFACVLFAFAALTYAHVTSDFSVQNVVENSHTQKP
LIYKISGVWGNHEGSMLLWVLILTLFGACVAAAKNSVPPRLRASTLGVQGLITFVFVLFIITTSNPFTRVIPAPLEGNDL
NPLLQDPGLAIHPPLLYVGYVGFSISFAFAVAALIDGRIDAVWARAVRPWTLAAWCFLTLGIAMGSYWAYYELGWGGWWF
WDPVENASLMPWIAGTALLHSTVVMEKRDALKVWTVLLAILTFSLSLIGTFLVRSGVITSVHSFATDPTRGVFILAILVL
FIGGSLTLFAWRAPLLRQGGLFAPISREGSLVLNNLFLVAACATVLVGTLYPLVLEMLTGEKITVGPPFFNSTFVPLAIP
LLLIVPMGQSLAWKRGDVLAAAQRLFAALAVALVVGFGVLALTWGGPVMAPVGIGLGAYLLIGSALEIVTRARGYGASRA
RSLGQIGRRAVGLPRSAWGTAIAHAGVGVVVLGIAAQGWATEGLATLKAGQSLATGPYVATLDRVAPRKGPNYEEAAAYL
TIRTRGGDEVGQVETGKRFYPSRKMAVTESGLLTVGASQVYASLGEIGQDGGVGLRLYYKPLVLLIWLGAVVMAVGGGLS
LTDRRMRVGVPAKAKARPLPVAVPAE

Sequences:

>Translated_666_residues
MIVETGHFALALALAISLVQVVMPIWAARSGDPALRQIASQAALGAFACVLFAFAALTYAHVTSDFSVQNVVENSHTQKP
LIYKISGVWGNHEGSMLLWVLILTLFGACVAAAKNSVPPRLRASTLGVQGLITFVFVLFIITTSNPFTRVIPAPLEGNDL
NPLLQDPGLAIHPPLLYVGYVGFSISFAFAVAALIDGRIDAVWARAVRPWTLAAWCFLTLGIAMGSYWAYYELGWGGWWF
WDPVENASLMPWIAGTALLHSTVVMEKRDALKVWTVLLAILTFSLSLIGTFLVRSGVITSVHSFATDPTRGVFILAILVL
FIGGSLTLFAWRAPLLRQGGLFAPISREGSLVLNNLFLVAACATVLVGTLYPLVLEMLTGEKITVGPPFFNSTFVPLAIP
LLLIVPMGQSLAWKRGDVLAAAQRLFAALAVALVVGFGVLALTWGGPVMAPVGIGLGAYLLIGSALEIVTRARGYGASRA
RSLGQIGRRAVGLPRSAWGTAIAHAGVGVVVLGIAAQGWATEGLATLKAGQSLATGPYVATLDRVAPRKGPNYEEAAAYL
TIRTRGGDEVGQVETGKRFYPSRKMAVTESGLLTVGASQVYASLGEIGQDGGVGLRLYYKPLVLLIWLGAVVMAVGGGLS
LTDRRMRVGVPAKAKARPLPVAVPAE
>Mature_666_residues
MIVETGHFALALALAISLVQVVMPIWAARSGDPALRQIASQAALGAFACVLFAFAALTYAHVTSDFSVQNVVENSHTQKP
LIYKISGVWGNHEGSMLLWVLILTLFGACVAAAKNSVPPRLRASTLGVQGLITFVFVLFIITTSNPFTRVIPAPLEGNDL
NPLLQDPGLAIHPPLLYVGYVGFSISFAFAVAALIDGRIDAVWARAVRPWTLAAWCFLTLGIAMGSYWAYYELGWGGWWF
WDPVENASLMPWIAGTALLHSTVVMEKRDALKVWTVLLAILTFSLSLIGTFLVRSGVITSVHSFATDPTRGVFILAILVL
FIGGSLTLFAWRAPLLRQGGLFAPISREGSLVLNNLFLVAACATVLVGTLYPLVLEMLTGEKITVGPPFFNSTFVPLAIP
LLLIVPMGQSLAWKRGDVLAAAQRLFAALAVALVVGFGVLALTWGGPVMAPVGIGLGAYLLIGSALEIVTRARGYGASRA
RSLGQIGRRAVGLPRSAWGTAIAHAGVGVVVLGIAAQGWATEGLATLKAGQSLATGPYVATLDRVAPRKGPNYEEAAAYL
TIRTRGGDEVGQVETGKRFYPSRKMAVTESGLLTVGASQVYASLGEIGQDGGVGLRLYYKPLVLLIWLGAVVMAVGGGLS
LTDRRMRVGVPAKAKARPLPVAVPAE

Specific function: Required for the biogenesis of c-type cytochromes. Possible subunit of a heme lyase [H]

COG id: COG1138

COG function: function code O; Cytochrome c biogenesis factor

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ccmF/cycK/ccl1/nrfE/ccsA family [H]

Homologues:

Organism=Escherichia coli, GI1788524, Length=658, Percent_Identity=44.8328267477204, Blast_Score=485, Evalue=1e-138,
Organism=Escherichia coli, GI1790511, Length=362, Percent_Identity=44.475138121547, Blast_Score=273, Evalue=2e-74,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002541
- InterPro:   IPR003567
- InterPro:   IPR003568 [H]

Pfam domain/function: PF01578 Cytochrom_C_asm [H]

EC number: NA

Molecular weight: Translated: 70547; Mature: 70547

Theoretical pI: Translated: 10.04; Mature: 10.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVETGHFALALALAISLVQVVMPIWAARSGDPALRQIASQAALGAFACVLFAFAALTYA
CEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HVTSDFSVQNVVENSHTQKPLIYKISGVWGNHEGSMLLWVLILTLFGACVAAAKNSVPPR
HHCCCCHHHHHHHCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCC
LRASTLGVQGLITFVFVLFIITTSNPFTRVIPAPLEGNDLNPLLQDPGLAIHPPLLYVGY
HHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCHHCCCCCEECCHHHHHHH
VGFSISFAFAVAALIDGRIDAVWARAVRPWTLAAWCFLTLGIAMGSYWAYYELGWGGWWF
HHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHCCCEEEEEECCCCEEE
WDPVENASLMPWIAGTALLHSTVVMEKRDALKVWTVLLAILTFSLSLIGTFLVRSGVITS
ECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VHSFATDPTRGVFILAILVLFIGGSLTLFAWRAPLLRQGGLFAPISREGSLVLNNLFLVA
HHHHCCCCCCHHHHHHHHHHHHCCCCEEHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHH
ACATVLVGTLYPLVLEMLTGEKITVGPPFFNSTFVPLAIPLLLIVPMGQSLAWKRGDVLA
HHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHH
AAQRLFAALAVALVVGFGVLALTWGGPVMAPVGIGLGAYLLIGSALEIVTRARGYGASRA
HHHHHHHHHHHHHHHHHHHHHEECCCCCHHHHHCCHHHHHHHHHHHHHHHHHCCCCHHHH
RSLGQIGRRAVGLPRSAWGTAIAHAGVGVVVLGIAAQGWATEGLATLKAGQSLATGPYVA
HHHHHHHHHHCCCCCHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHCCCCCCCCCHHH
TLDRVAPRKGPNYEEAAAYLTIRTRGGDEVGQVETGKRFYPSRKMAVTESGLLTVGASQV
HHHHHCCCCCCCHHHHEEEEEEEECCCCCCCCCCCCCCCCCCCCEEEECCCCEEECHHHH
YASLGEIGQDGGVGLRLYYKPLVLLIWLGAVVMAVGGGLSLTDRRMRVGVPAKAKARPLP
HHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCCCCCCCCC
VAVPAE
EECCCC
>Mature Secondary Structure
MIVETGHFALALALAISLVQVVMPIWAARSGDPALRQIASQAALGAFACVLFAFAALTYA
CEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HVTSDFSVQNVVENSHTQKPLIYKISGVWGNHEGSMLLWVLILTLFGACVAAAKNSVPPR
HHCCCCHHHHHHHCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCC
LRASTLGVQGLITFVFVLFIITTSNPFTRVIPAPLEGNDLNPLLQDPGLAIHPPLLYVGY
HHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCHHCCCCCEECCHHHHHHH
VGFSISFAFAVAALIDGRIDAVWARAVRPWTLAAWCFLTLGIAMGSYWAYYELGWGGWWF
HHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHCCCEEEEEECCCCEEE
WDPVENASLMPWIAGTALLHSTVVMEKRDALKVWTVLLAILTFSLSLIGTFLVRSGVITS
ECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VHSFATDPTRGVFILAILVLFIGGSLTLFAWRAPLLRQGGLFAPISREGSLVLNNLFLVA
HHHHCCCCCCHHHHHHHHHHHHCCCCEEHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHH
ACATVLVGTLYPLVLEMLTGEKITVGPPFFNSTFVPLAIPLLLIVPMGQSLAWKRGDVLA
HHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHH
AAQRLFAALAVALVVGFGVLALTWGGPVMAPVGIGLGAYLLIGSALEIVTRARGYGASRA
HHHHHHHHHHHHHHHHHHHHHEECCCCCHHHHHCCHHHHHHHHHHHHHHHHHCCCCHHHH
RSLGQIGRRAVGLPRSAWGTAIAHAGVGVVVLGIAAQGWATEGLATLKAGQSLATGPYVA
HHHHHHHHHHCCCCCHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHCCCCCCCCCHHH
TLDRVAPRKGPNYEEAAAYLTIRTRGGDEVGQVETGKRFYPSRKMAVTESGLLTVGASQV
HHHHHCCCCCCCHHHHEEEEEEEECCCCCCCCCCCCCCCCCCCCEEEECCCCEEECHHHH
YASLGEIGQDGGVGLRLYYKPLVLLIWLGAVVMAVGGGLSLTDRRMRVGVPAKAKARPLP
HHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCCCCCCCCC
VAVPAE
EECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7715602; 11481430 [H]